Clinical trials: Delirium, completed
Cardiac Surgery
Risk of Oxygen During Cardiac Surgery Trial
The investigators will recruit and randomize 200 elective cardiac surgery patients to receive physiologic oxygenation (normoxia) or hyper-oxygenation (hyperoxia) during surgery to test the hypothesis that intraoperative…
- Trial name
- ROCS (NCT02361944)
- Testing
- Oxygen - normoxia, Oxygen - hyperoxia
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- Vanderbilt University
Post Operative Cognitive Dysfunction
Ketamine and Postoperative Cognitive Dysfunction
Over 30 million patients require a major surgery annually in the US alone and more than half of them are performed in patients over 60 years of age.
- Trial name
- POCK (NCT02892916)
- Testing
- Ketamine
- Where
- France
- Volunteers
- 307 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Delirium
Implementation Outcome Assessments of the Emergency Department Delirium Screening and Detection Program
Delirium occurs in up to 20% of older adults presenting to the Emergency Department (ED) and is associated with poor outcomes. Failure to identify patients with ED delirium not only prevents initiation of mitigation strategies…
- Trial name
- ED-DDP (NCT05606328)
- Testing
- Emergency Department Delirium Screening and Detection Program (ED-DDP)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Immobility Syndrome, Fall
Goal-directed Mobilization of Medical Inpatients
Immobilization in general internal medicine inpatients is a major contributor to morbidity and mortality. Goal-directed mobilization (GDM) may improve mobility.
- Conditions
- Immobility Syndrome, Fall, Delirium, Sarcopenia
- Trial name
- GoMob-in (NCT04760392)
- Testing
- Goal-directed mobilization
- Where
- Switzerland
- Volunteers
- 160 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Delirium
Delirium in the Emergency Department and Its Extension Into Hospitalization
Delirium occurs in 10% of older emergency department (ED) patients, yet it remains poorly understood. To date, the predominance of delirium studies have been conducted in hospitalized patients and therefore have limited…
- Trial name
- DELINEATE (NCT01651897)
- Where
- United States
- Volunteers
- 228 people
- Sponsor
- Vanderbilt University
Recovery, Analgesia And Delirium Profiles At Laparoscopic Abdominal and Gynecologic Surgeries With Processed EEG Monitoring
Recovery, Analgesia And Delirium Profiles At Laparoscopic Abdominal and Gynecologic Surgeries With Processed EEG Monitoring
The aim of this study is to evaluate the effects of processed electroencephalogram (pEEG) monitoring on recovery and extubation times, length of stay in the post-anesthesia care unit (PACU), postoperative pain, patient comfort…
- Trial name
- TandRT (NCT07670689)
- Testing
- Bispectral index monitoring
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 136 people
- Sponsor
- Cukurova University
Delirium, Awakening, Post-Anesthesia Delayed
Validation and Reliability of the Turkish 4AT Scale for Post-Anesthesia Awakening Delirium
Background: Delirium is a common and serious condition in hospitalized patients that often leads to extended hospital stays and increased healthcare costs. Accurate and timely detection is essential for optimal patient outcome.
- Conditions
- Delirium, Awakening, Post-Anesthesia Delayed, Delirium, Postoperative, Nurse's Role
- Trial name
- NCT06187389
- Testing
- 1 Grups
- Where
- Turkey (Türkiye)
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Kilis 7 Aralik University
Delirium, Pain
Evaluation of Quality Indicators on Analgesia, Sedation and Delirium in Intensive Care Patients and Their Impact on Outcome Indicators and Economic Indicators
Retrospective cohort study to investigate the adherence to the process indicators for pain management, sedation management and management of delirium on outcome indicators and cost/revenues in individual patients and subcohorts.
- Trial name
- NCT05384613
- Where
- Germany
- Volunteers
- 20,220 people
- Sponsor
- Charite University, Berlin, Germany
Paediatric Anesthesia Emergence Delirium
Evaluation and Implementation of the "Paediatric Anesthesia Emergence Delirium Scale" (PAED) in the PACU in Children Under 14 Years of Age
The goal of this study is to determine the incidence and characteristics of Emergence Delirium (ED) in children aged 0 - 13 undergoing general anesthesia and being taken care of at the paediatric PACU of the Charité Campus…
- Trial name
- NCT02358278
- Where
- Germany
- Volunteers
- 821 people
- Sponsor
- Charite University, Berlin, Germany
Delirium
Decreasing Delirium Through Music
DDM is a study designed to Test the efficacy of personalized music therapy in reducing delirium incidence and severity among patients admitted to the Intensive Care Unit.
- Trial name
- DDM (NCT03095443)
- Testing
- Music Therapy - Personalized Playlist, Music Therapy - Standard Playlist, Attention Control
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Indiana University
Delirium, Falls
Prophylactic Environmental Management of Delirium
Delirium is a complex neuropsychiatric syndrome with an acute onset and fluctuating course which is presented in 15 to 20% of patients admitted to general wards.
- Trial name
- MAPDI (NCT01356810)
- Testing
- Environmental Intervention, Standard Care
- Where
- Chile
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Postoperative Delirium, Elderly Patients
The Effects of Subanesthetic S-ketamine on Postoperative Delirium and Cognitive Function in the Elderly Undergoing Non-cardiac Thoracic Surgery
Postoperative delirium (POD) is a common and distressing complication after thoracic surgery. S-ketamine has neuroprotective properties as a dissociative anesthetic.
- Trial name
- SKED (NCT05242692)
- Testing
- S-ketamine, Dexmedetomidine
- Where
- China
- Volunteers
- 520 people
- Sponsor
- Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Cohort Studies
The Relationship Between Preoperative Anxiety and Postoperative Delirium in Elderly Chinese Patients
This study is a retrospective analysis of a large-scale multicentre prospective cohort study that investigates the the relationship between Preoperative Anxiety and Postoperative Delirium in Elderly Chinese Patients: a…
- Trial name
- NCT06861764
- Where
- China
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Delirium, Critical Illness
Pharmacokinetics and Clinical Effects of Escalating Doses of Clonidine in ICU Patients
This study is developed for assessing the pharmacodynamic and pharmacokinetic properties of intravenous (IV) clonidine in critically ill patients on the ICU, and to estimate the optimal dosing strategy for IV clonidine.
- Trial name
- Clokin1 (NCT02466373)
- Testing
- Clonidine (Catapresan®) 0,150 mg/ml, ampoule 1 ml
- Where
- Netherlands
- Volunteers
- 32 people
- Sponsor
- Deventer Ziekenhuis
Septic Shock, Delirium
Septic Shock and Delirium Because of rSO2 Abnormalities in Intensive Care Unit Patients (The SAD BRAIN Study)
Delirium in the ICU is a prevalent problem occurring in up to 80% of ICU patients. A potential cause of delirium in ICU patients could be cerebral hypoxia. Septic shock is associated with high rates of delirium.
- Conditions
- Septic Shock, Delirium, Renal Failure
- Trial name
- NCT01836302
- Testing
- Observation
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Manitoba
Insulin Resistance, Inflammation
Effect of Oral Carbohydrate on Serum S-100β Protein and Development of Postoperative Delirium in Elderly Patients
This study is to evaluate the effects of preoperative carbohydrate intake on perioperative neuroinflammation and development of delirium.
- Conditions
- Insulin Resistance, Inflammation, Delirium
- Trial name
- NCT02706522
- Testing
- Allocated to Carbohydrated group
- Volunteers
- 3 people
- Sponsor
- Gangnam Severance Hospital
Delirium in Old Age
REPOSE Study: Reducing Delirium by Enhancing Postoperative Sleep With Suvorexant
This research study will evaluate the effectiveness of postoperative administration of a drug called suvorexant, to improve postoperative sleep and decrease the severity of delirium (serious confusion) in adults 65 years and…
- Trial name
- REPOSE (NCT05733286)
- Testing
- Suvorexant 20 mg
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Duke University
Delirium
Vitamin D Level and Emergence Delirium in Children
In our study, we aimed to evaluate the relationship between vitamin D levels and postoperative delirium in children who had undergone tonsillectomy and/or adenoidectomy.
- Trial name
- NCT05076162
- Testing
- PAED
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people
- Sponsor
- Aydin Adnan Menderes University
Tonsillectomy
Dexmedetomidine as a Rapid Bolus in Children for Emergence Agitation
To Determine The Efficacy of a Rapid Bolus Injection of Dexmedetomidine on the Incidence of Emergence Agitation in Anesthetized Children and the Cardiovascular Profile of a Rapid Bolus Injection of Dexmedetomidine.
- Trial name
- NCT01528891
- Testing
- Dexmedetomidine
- Where
- 2 sites in United States
- Volunteers
- 418 people
- Sponsor
- Peter Davis
Alcohol Withdrawal Syndrome
MAGnesium Adjunction in Alcohol Withdrawal Syndrome: a Multicenter Assessment (MAGMA)
This study examine the efficacy of oral magnesium supplementation as an adjuvant therapy for decreasing intensity of alcohol withdrawal symptoms among inpatients requiring pharmacological treatment of their AWS.
- Trial name
- MAGMA (NCT03033823)
- Testing
- Magnesium
- Where
- 11 sites in France
- Volunteers
- 105 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris