Clinical trials: Delirium Confusional State
Oral Health
A Study on the Correlation Between Oral Health and Delirium in Surgical Inpatients
Delirium is a clinical syndrome characterized by acute attention deficits, altered consciousness, and fluctuating cognitive dysfunction, typically triggered by multifactorial causes such as physical illness, medication use, or…
- Trial name
- NCT06969092
- Testing
- Oral Frailty
- Where
- China
- Volunteers
- 550 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Fraily, Abdominal Surgery
Awareness Neuraxial Versus General Anesthesia in Frail Patients Undergoing Laparoscopic or Robotic Abdominopelvic Surgery.
This is a bicentric, prospective, non-pharmacological, randomized study designed to compare the efficacy and safety of awake neuraxial anesthesia with sedation versus general anesthesia in frail patients undergoing elective major…
- Conditions
- Fraily, Abdominal Surgery, Postoperative Cognitive Dysfunction (POCD)
- Trial name
- SAFE-AWARENESS (NCT07486336)
- Testing
- Neuraxial anesthesia, General Anesthesia, avoidance of GABAergic-drugs strategy
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Ente Ospedaliero Ospedali Galliera
Preoperative Anxiety, Postoperative Delirium
Effects of Preoperative Anxiety and Preemptive Analgesia on Postoperative Delirium in Septo/Rhinoplasty Surgery
Effects of Preoperative Anxiety and Preemptive Analgesia on Postoperative Delirium in Septo/Rhinoplasty Surgery
- Trial name
- NCT07010042
- Testing
- The Beck Anxiety Inventory (BAI) of adult patients
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Zonguldak Bulent Ecevit University
Dexmedetomidine, Delirium
The Mechanism of Dexmedetomidine in Improving Delirium After Cardiac Surgery
The investigators aim to evaluate the roles of α7nAchR in the mechanisms of dexmedetomidine in improving delirium after cardiac surgery.
- Conditions
- Dexmedetomidine, Delirium, Cardiac Surgery
- Trial name
- NCT04127500
- Testing
- dexmedetomidine
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Brain Injuries, Traumatic, Confusional State
Multisensory Stimulation and Enriched Environments During Post-traumatic Amnesia
The objective of this Phase II trial is to evaluate the feasibility of this study protocol to progress to a large-scale Phase III RCT in the future.
- Conditions
- Brain Injuries, Traumatic, Confusional State, Sensory Motor System Disorder, Alteration of Cognitive Function
- Trial name
- NCT02792985
- Testing
- Multisensory stimulation protocol, Control protocol
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Institut Guttmann
Delirium
Digital Rehabilitation Environment Augmenting Medical System
D.R.E.A.M.S. will assess an immersive digital reality-augmenting system in reducing the occurrence of cognitive, behavioral, and emotional consequences of critical illness and environmental exposures that are risk factors for the…
- Trial name
- DREAMS (NCT03385993)
- Testing
- Technology based guided meditation and relaxation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Florida
General Anesthesia, Geriatric Patient
Sevoflurane and Propofol Anesthesia on Postoperative Delirium
Delirium is defined as an acute onset and fluctuating course of mental status change with inattention and an altered level of consciousness.
- Trial name
- NCT01995214
- Testing
- Propofol, Sevoflurane
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Huazhong University of Science and Technology
Delirium
Rivastigmine in the Management of Delirium
The aim of this study is to evaluate the efficacy of an anticholinesterase treatment in patients aged 75 and over, hospitalized with delirium.
- Trial name
- confuriv (NCT01487317)
- Testing
- Rivastigmine transdermal patch
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Delirium on Emergence
Post Anesthesia Emergence and Behavioral Changes in Children Undergoing MRI
Children who receive general anesthesia may become agitated (emergence delirium) in the recovery period. This occurs more often after inhalational anesthetics, particularly sevoflurane and desflurane than after propofol.
- Trial name
- NCT02111447
- Testing
- Propofol, Sevoflurane, Isoflurane
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- State University of New York at Buffalo
Coronary Artery Disease, Cognitive Impairment
Cerebral Oxygenation and Neurological Functioning After Cardiac Surgery
The overall goal of this research program is to determine quantitative predictors of quantitative long-term neurological functioning following different cardiac surgery procedures.
- Conditions
- Coronary Artery Disease, Cognitive Impairment, Delirium
- Trial name
- CONFUSE (NCT04081649)
- Where
- Canada
- Volunteers
- 95 people
- Sponsor
- Dr. Gordon Boyd
Delirium, Dementia
Delirium and Cognitive Impairment Development in Hospitalized Older Adults Under Isolation Conditions
The goal of this observational study is to examine if older patients who need to be under isolation precautions due to multidrug resistant bacteria or other reasons have an increased risk of suffering from delirium or cognitive…
- Conditions
- Delirium, Dementia, Cognitive Impairment
- Trial name
- DELiso (NCT07114458)
- Where
- Germany
- Volunteers
- 404 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Delirium, Anxiety
Patient- and Family-centred Care in the Adult Intensive Care Unit: a Feasibility Study
Background: In the intensive care unit (ICU), delirium in patients and long-term mental health challenges in both patients and their family members are highly prevalent.
- Conditions
- Delirium, Anxiety, Post Intensive Care Unit Syndrome, Post Intensive Care Unit Syndrome Family
- Trial name
- FAM-ICU (NCT06974214)
- Testing
- FAM-ICU
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Poor Quality Sleep, Sleep Deprivation
The Comparison of Dexmedetomidine and Midazolam for the Sleep in Intensive Care Unit
The investigators are going to compare the sleep quality and quantity between dexmedetomidine group and midazolam group using 24 hour polysomnography in critically ill patients.
- Conditions
- Poor Quality Sleep, Sleep Deprivation, Sleep Arousal Disorders, Delirium
- Trial name
- NCT01966315
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- Seoul National University Hospital
Postoperative Delirium, Aging Disorder
Non-pharmacological Prevention of Postoperative Delirium by Occupational Therapy Teams
In the world, 230 million surgeries are performed every year and US data indicates that more than a third of patients who undergo surgery are older than 65 years, in which between 10 and 70% develop postoperative delirium (POD).
- Trial name
- PREPODOT (NCT03704090)
- Testing
- Occupational therapy intervention, Standard non-pharmacological prevention intervention
- Where
- Chile
- Volunteers
- 160 people
- Sponsor
- University of Chile
Acute Kidney Injury, Delirium
AKI and Delirium Risk Prediction and Cost Burden Study
The goal of this study is to learn how to better predict two common health problems that can happen during a hospital stay: acute kidney injury (AKI) and delirium. AKI is a sudden decline in kidney function.
- Trial name
- HAAKID (NCT07866560)
- Testing
- It is observational trial with no intervention being evaluated
- Where
- United States
- Volunteers
- 25,000 people
- Sponsor
- University of Nebraska
Nurse's Role
Patient-related Effects of Primary Nursing
After a one-year phase of development, primary nursing (process-responsible nursing; PP) has been practically implemented on a pilot ICU since January 2022 at the Heart and Diabetes Center NRW.
- Trial name
- ENGAGE (NCT05569317)
- Testing
- primary nursing
- Where
- Germany
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Heart and Diabetes Center North-Rhine Westfalia
Confusion, Inflammation
Confusion in the Elderly After Colon Surgery
A study will be conducted to determine if there is any cognitive benefit in elderly patients having open versus minimally invasive colon cancer surgery.
- Conditions
- Confusion, Inflammation, Acute Phase Reaction, Surgery
- Trial name
- NCT01623297
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- New York Hospital Queens
Cognitive Impairment, Delirium
e-CHAMP: Enhancing Care for Hospitalized Older Adults With Memory Problems
The purpose of this study is to evaluate the effectiveness of a cognitive screening program coupled with a computerized decision support system in improving the quality of care for hospitalized older adults with cognitive…
- Trial name
- NCT00182832
- Testing
- e-CHAMP (Enhancing Care for Hospitalized Older Adults with Cognitive Impairment), Standard Care
- Where
- United States
- Volunteers
- 424 people
- Sponsor
- Indiana University
Postoperative Delirium
EPO for Postop Delirium in Elderly Patients
Postoperative delirium is a common complication after surgery. The underlying pathophysiology of this complication is unclear, however neuroinflammation and oxidative stress secondary to surgery had shown to be the cause of…
- Trial name
- NCT06178835
- Testing
- Erythropoietin, normal saline
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- Yonsei University
Postoperative Delirium, Gastrointestinal Tumors
Opioid-free Anesthesia and Postoperative Delirium
Postoperative delirium (POD) is a common acute and transient form of brain dysfunction in elderly patients following surgery that can lead to serious adverse clinical outcomes and even death.
- Trial name
- NCT07603596
- Testing
- OFA group, OBA group
- Volunteers
- 174 people
- Sponsor
- Qianfoshan Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.