Clinical trials: Delirium Treatment
Delirium in Old Age, Delirium of Mixed Origin
Music Therapy as a Treatment for Delirium in Acutely Hospitalized Older Patients
The purpose of this study is to assess feasibility and potential effectiveness of two different music interventions for managing delirium symptoms in acute geriatric patients.
- Conditions
- Delirium in Old Age, Delirium of Mixed Origin, Delirium Superimposed on Dementia, Delirium Confusional State
- Trial name
- NCT05398211
- Testing
- Preferred Recorded Music (PRM), Preferred Live Music (PLM)
- Where
- Norway
- Volunteers
- 26 people
- Sponsor
- Oslo University Hospital
Emergence Delirium, Agitation, Emergence
Mitigation of Emergence Agitation Through Implementation of Masimo Bridge Therapy
This is a randomized, prospective, double-blinded (patient and outcome-assessor) trial. Our goal is to assess efficacy of Bridge Therapy (versus sham bridge therapy) to prevent emergence agitation following general anesthesia.
- Trial name
- NCT06387953
- Testing
- Bridge Therapy
- Sponsor
- University of Washington
Premedication
Oral Dexmedetomidine vs Midazoam For Premedication
The aim of this study was to compare the effect of 2 µg/kg of oral dexmedetomidine (DEX) and 0.5 mg/kg dormicum as premedication among children undergoing dental procedures.
- Trial name
- NCT03357718
- Testing
- Precedex, Midazolam
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Emergence Delirium, Perioperative Neurocognitive Disorder
Quantitative Neurofeedback Techniques for Treating Perioperative Cognitive Disorders in Elderly Patients
The goal of this clinical trial is to learn if quantitative measurement of brain and neurofeedback intervention techniques works to prevent perioperative neurocognitive deficits in elderly oncology patients who are to undergo…
- Trial name
- NCT06752148
- Testing
- neurofeedback intervention training game
- Volunteers
- 390 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Delirium
DELIRIUM SCREENING, INCIDENCE AND MANAGEMENT OBSERVATIONAL STUDY IN 2024 - THE CZECH REPUBLIC
Delirium in intensive care unit (ICU) settings is a frequent complication with reported prevalence of 31%. Recent data has revealed the connection between delirium and increased 30days mortality after hospital release and the…
- Trial name
- DELUSION (NCT05841368)
- Testing
- CAM-ICU, pCAM-ICU
- Where
- Czechia
- Volunteers
- 2,000 people
- Sponsor
- Brno University Hospital
Postoperative Delirium, Aging Disorder
Non-pharmacological Prevention of Postoperative Delirium by Occupational Therapy Teams
In the world, 230 million surgeries are performed every year and US data indicates that more than a third of patients who undergo surgery are older than 65 years, in which between 10 and 70% develop postoperative delirium (POD).
- Trial name
- PREPODOT (NCT03704090)
- Testing
- Occupational therapy intervention, Standard non-pharmacological prevention intervention
- Where
- Chile
- Volunteers
- 160 people
- Sponsor
- University of Chile
Critical Illness, Delirium
Family Integration in Therapy Activities in the Intensive Care Unit: The FIT-ICU Feasibility Study
An ICU admission is stressful for not only patients but their families as well. Research has shown that involving family members during a loved one's ICU stay can be helpful for them, but there is not clear direction on the best…
- Trial name
- FIT-ICU (NCT06071793)
- Testing
- Family involvement
- Where
- 3 sites in Canada
- Volunteers
- 20 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Neurocognitive Impairment, Delirium
Neurocognitive Functioning in Patients With Newly Diagnosed Upper Aerodigestive Tract Cancer Receiving Treatment at Henry-Joyce Cancer Clinic
RATIONALE: Gathering information about how often problems with neurocognitive functioning occur in patients with newly diagnosed upper aerodigestive tract cancers may help doctors learn more about the disease.
- Conditions
- Neurocognitive Impairment, Delirium, Esophageal Cancer, Head and Neck Cancer
- Trial name
- NCT00533884
- Testing
- Assessment of therapy complications, Neurocognitive assessment, Quality-of-life assessment
- Where
- 4 sites in United States
- Volunteers
- 86 people
- Sponsor
- Vanderbilt University Medical Center
Delirium
Occupational Therapy Intervention on the Prevention of Delirium and Occupational Performance Status in Elderly Patients
Delirium is an acute, fluctuating, transient, and usually reversible disorder of cognition and level of consciousness, with a high incidence in critical care units, especially in the elderly.
- Trial name
- NCT06479031
- Testing
- Occupational Therapy
- Volunteers
- 114 people
- Sponsor
- Hospital Sirio-Libanes
Schizophrenia
Bifrontal and Bitemporal Electroconvulsive Therapy (ECT) in Treatment of Patients With Schizophrenia
Electroconvulsive therapy has been used in clinical practice since 1938, a number of randomized trials found significant differences favoring ECT in response rates between individuals with depression receiving real and sham ECT.
- Trial name
- ESBECT (NCT02511509)
- Testing
- Bifrontal electroconvulsive therapy, Bitemporal electroconvulsive therapy
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Lodz
Delirium
VoiceLove Digital Therapy for Delirium in the ICU
The study is a single-center, single-arm, prospective trial to evaluate the feasibility, safety, and acceptability of VoiceLOVE digital therapy for the management of delirium in surgical ICU patients.
- Trial name
- NCT07218484
- Testing
- VoiceLove therapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The Methodist Hospital Research Institute
Delirium, Agitation
Randomized Controlled Trial of Dexmedetomidine for the Treatment of Intensive Care Unit (ICU) Delirium
The purpose of the research is to see if dexmedetomidine (a drug that has a calming effect - a sedative) is effective for the treatment of acute delirium
- Trial name
- NCT00351299
- Testing
- Dexmedetomidine, Standard of Care
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Brigham and Women's Hospital
Cognitive Decline, Heart Diseases
The Effect of Intranasal Insulin Administration on Cognitive Function After Cardiac Surgery.
Decline in cognitive function after surgery occurs most commonly in older patients and patients undergoing major surgeries, such as heart surgery.
- Conditions
- Cognitive Decline, Heart Diseases, Delirium
- Trial name
- NCT03324867
- Testing
- Regular insulin, Normal Saline Flush, 0.9% Injectable Solution
- Volunteers
- 316 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Delirium
Trial Comparing Haloperidol, Quetiapine and Placebo in the Pharmacological Treatment of Delirium
Background: Delirium is an important problem in critical care. Its prevalence often reaches 75% in intensive care patients. Its occurrence is associated with numerous complications and deleterious consequences such as death…
- Trial name
- Haloquet (NCT01811459)
- Testing
- Quetiapine, Haloperidol
- Where
- Canada
- Volunteers
- 107 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Anesthesia, Thirst; Due to Deprivation of Water
Benefits of Drinking Clear Fluids Until Called to the Operating Room in Adult Surgical Patients
The purpose of this study is to show if - compared to standard practice - allowing adults undergoing surgical procedures under anaesthesia care to drink clear fluids up to a volume of 200 ml between 2 h prior to the operation and…
- Conditions
- Anesthesia, Thirst; Due to Deprivation of Water, Aspiration
- Trial name
- HYDRATE (NCT06253052)
- Testing
- Additional pre-OP-visit, Liberal fasting regime
- Where
- Germany
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Delirium
Prevention of Delirium After Bone Marrow Transplantation
The purpose of this study is to find out if using bright light sessions during bone marrow transplant can prevent people from developing confusion also known as delirium.
- Trial name
- NCT01700816
- Testing
- Bright light therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Delirium, Surgery-Complications
Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac Surgery
The investigation will establish biological plausibility and infrastructure required for a multisite clinical trial evaluating the re-purposing of fluvoxamine to mitigate postoperative delirium risk in geriatric patients…
- Trial name
- MD FluNCS (NCT06969287)
- Testing
- Fluvoxamine
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Washington University School of Medicine
Delirium
Incidence, Severity and Treatment of Delirium in Cardiac Surgery Patients: A Before-after Study
Delirium is a common yet under diagnosed condition in hospitalized patients, and the incidence have not previously been described in Danish cardiac surgery patients.
- Trial name
- NCT01774240
- Testing
- systematic screening and treatment of delirium
- Where
- Denmark
- Volunteers
- 230 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Suspected Delirium After Elective or Emergency Heart Surgery, CAM-ICU Diagnosed Delirium
Evaluation if Physostigmine Reduces Symptoms in Patients Who Has Developed a Delirium in Intensive Care After a Surgery
Evaluation if physostigmine reduces symptoms in patients who has developed a delirium in Intensive care after a surgery
- Trial name
- NCT02216266
- Testing
- Physostigmine, Sodium Chloride solution
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- PD Dr. Bertram Scheller
Anxiety, Preoperative Care
A Study of Dexmedetomidine Pharmacokinetics for Preoperative Sedation
Proper preoperative sedation can reduce patients' anxiety, enhance patients' cooperation and reduce perioperative complications.
- Conditions
- Anxiety, Preoperative Care, Pharmacokinetics, Emergence Delirium
- Trial name
- NCT03800641
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Eye & ENT Hospital of Fudan University