Clinical trials: Delivery Delayed
X-Linked Myotubular Myopathy
A Study of AT132 in Young Children With X-Linked Myotubular Myopathy (XLMTM)
X-linked myotubular myopathy (XLMTM) is a rare and serious condition present at birth where the muscles do not work properly. There are currently no therapies for this serious condition.
- Trial name
- ASPIRO (NCT03199469)
- Testing
- Resamirigene bilparvovec
- Where
- 6 sites in United States, Canada and 2 more
- Volunteers
- 27 people
- Sponsor
- Astellas Gene Therapies
Sepsis, Length of Stay
Limited Versus Extended Trophic Feeding (LET-FEED) Trial
Study Hypothesis/Question In infants born very preterm, advancing enteral feeds after 24 hours from birth (limited trophic feeds) versus after 72 hours (extended trophic feeds) reduces the risk of all-cause late onset sepsis…
- Conditions
- Sepsis, Length of Stay, Mortality, Neurodevelopmental Delay
- Trial name
- LET-FEED (NCT06893939)
- Testing
- Limited Trophic Feeds (1 day of trophic feeds), Extended Trophic Feeds (3 days of trophics)
- Where
- 6 sites in United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Washington
Female Infertility
What is the Best Moment for Performing an HSG in Women With a Unfulfilled Childwish
The aim of this study is to determine whether direct tubal flushing with oil-based contrast at HSG incorporated in the fertility work-up results in 10% more ongoing pregnancies and a shorter time to pregnancy, which will…
- Trial name
- H2Oil-timing (NCT05608590)
- Testing
- Lipiodol UltraFluid
- Where
- Netherlands
- Volunteers
- 554 people
- Sponsor
- Amsterdam UMC, location VUmc
Low Birth Weight, Perinatology
Effect of Delayed Cord Clamping on Haematological Status in Low Birth Weight Infants
Delayed cord clamping (DCC, clamping after cessation of pulsations in the cord around 2-3 min after delivery) is effective in increasing (low birth weight) infant haemoglobin and iron status until six months after birth, without…
- Conditions
- Low Birth Weight, Perinatology, Iron Status, Cord Clamping
- Trial name
- NCT01487980
- Testing
- Cord clamping
- Where
- South Africa
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Stanger Hospital
Cesarean Delivery, Delayed Separation of Umbilical Cord
Timing of Umbilical Cord Clamping in Term Cesarean Deliveries
The aim of this study is to show that delayed umbilical cord clamping or milking of the umbilical cord in pregnant women undergoing elective cesarean delivery might have better effects than early clamping, on neonatal results…
- Trial name
- NCT04812223
- Testing
- Delayed umbilical cord clamping, Early umbilical cord clamping, Milking of the umbilical cord
- Where
- Turkey (Türkiye)
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Gestational Diabetes Mellitus, Neonatal Hyperbilirubinemia
Effect of DCC on Neonatal Jaundice and Blood Gas Analysis in Infants Born to GDM Mothers
Evidence for benefited newborns following delayed cord clamping (DCC), including increasing hemoglobin and hematocrit levels, improving iron stores, and decreasing need for blood transfusion and incidence of intraventricular…
- Conditions
- Gestational Diabetes Mellitus, Neonatal Hyperbilirubinemia, Neonatal Asphyxia
- Trial name
- NCT04369313
- Testing
- delayed cord clamping, early cord clamping
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Crohn's Disease
Efficacy Study of Targeted, Local Delivery of Drugs to Treat Crohn's Disease
The study is being undertaken to evaluate whether delayed-release medications, designed to begin to open in the lower intestinal tract, the main site of Crohn's Disease, are more effective than standard systemically delivered…
- Trial name
- NCT00287170
- Testing
- Delayed Release 6MP or Calcitriol vs. Purinethol
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Teva GTC
HIV-1 Infection, Receipt of Cal-1 Modified Hematopoietic Cellular Products
Long Term Follow up for the Detection of Delayed Adverse Events in Cal-1 Recipients
Long term safety follow-up of Cal-1 recipients
- Trial name
- NCT02390297
- Testing
- Blood tests
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Calimmune, Inc.
Maternal Blood Loss, Cesarean Delivery
Delayed Cord Clamping at Term Cesarean
The purpose of this research study is to find out how delaying cutting the umbilical cord until one minute after delivery of the baby during a cesarean impacts the amount of blood the mother loses during surgery.
- Conditions
- Maternal Blood Loss, Cesarean Delivery, Delayed Cord Clamping, Neonatal Health
- Trial name
- NCT03150641
- Testing
- Umbilical cord clamping
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Columbia University
Motor Delay, Premature Birth
Effects of a Physical Therapy Intervention on Motor Delay in Infants Admitted to a Neonatal Intensive Care Unit
Study Aims Pilot study: Due to the large recruitment goal and length of the project, the study team/PIs will evaluate the first cohort of 6-10 participants to refine study procedures and study-related materials.
- Conditions
- Motor Delay, Premature Birth, Intraventricular Hemorrhage, Hypoxic-Ischemic Encephalopathy
- Trial name
- NCT05568264
- Testing
- Physical Therapy intervention
- Where
- 3 sites in United States
- Volunteers
- 222 people
- Sponsor
- Shirley Ryan AbilityLab
Deferred Umbilical Cord Clamping
Physiological Effects of Deferred Cord Clamping
This is an observational study to see if at birth, flow of blood from a placenta to the baby can be estimated non-invasively using Doppler ultrasound and/or cutaneous perfusion measured using a novel PPG sensor.
- Trial name
- DoppCord (NCT01864421)
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Nottingham
Wound Complications, Obesity
Early Versus Delayed Skin Staple Removal Following Cesarean Delivery in the Obese Patient
Whenever a person has a cesarean section there is a risk that there will be a problem with healing of the wound. The most common type of wound healing problem is separation and opening of the skin and fatty tissue just beneath…
- Trial name
- NCT01114451
- Testing
- Removal of surgical skin staples
- Where
- United States
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- Prisma Health-Upstate
Cesarean Section, Hypotension
Prevention of Post-spinal Anesthesia Hypotension in Caesarean Delivery Using Delayed Supine Positioning
Maternal hypotension is a common complication after spinal anaesthesia for caesarean delivery. Prophylaxis against post-spinal hypotension (PSH) during caesarean delivery would prevent serious maternal and fetal complications.
- Conditions
- Cesarean Section, Hypotension, Spinal Anaesthesia
- Trial name
- NCT04777123
- Testing
- sitting position
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Cairo University
Chemotherapy-induced Nausea and Vomiting (CINV)
Granisetron Transdermal Patch for Prophylaxis of Delayed CINV
Transdermal granisetron has been shown to as effective as oral/ intravenous granisetron when administered with or without dexamethasone.
- Trial name
- NCT04912271
- Testing
- Granisetron transdermal patch, Palonosetron, Aprepitant
- Volunteers
- 140 people
- Sponsor
- Fudan University
Pre-eclampsia, Pregnancy
Evaluation of the Efficacy of Citrulline Supplementation on the Delay of Delivery for Women Hospitalized for Pre-eclampsia (CITRUPE)
Pre-eclampsia (PE) complicates 2-8 % of pregnancies and is associated with high maternal and fetal morbidity and mortality. The early clinical manifestations are the occurrence of a maternal blood pressure and proteinuria.
- Trial name
- CITRUPE (NCT02801695)
- Testing
- Citrulline
- Where
- 2 sites in France
- Volunteers
- 116 people
- Sponsor
- Nantes University Hospital
Relapse
Comparison of Retention Characteristics of Immediate vs Delayed Retainer Delivery Using 3D Digital Model Analysis
Retention has been defined as "the holding of teeth following orthodontic treatment in the treated position for the period of time necessary for the maintenance of the result".
- Trial name
- NCT06292364
- Testing
- immediate orthodontic retainer delivery, delayed orthodontic retainer delivery
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Prematurity, Neurodevelopmental Disorders
Prevention of Developmental Delay and Xylitol (PDDaX) Study
The goals of this study are to: evaluate and validate the low-cost, transportable, easily-administered Malawi Developmental Assessment Tool (MDAT) for neurodevelopmental assessment of children aged 4-8 years old in Malawi, as…
- Trial name
- NCT05361122
- Testing
- Maternal Use of Xylitol Chewing Gum During Pregnancy, No Maternal Xylitol Chewing Gum Use During Pregnancy
- Where
- Malawi
- Volunteers
- 1,000 people
- Sponsor
- University of Washington
Prematurity, Developmental Delays
HEP® Delivered Via Telerehabilitation for Preterm Infants With Developmental Risks
Preterm infants are at increased risk for developmental delays, making early intervention essential for optimizing developmental outcomes.
- Trial name
- HEP-Preterm (NCT07725367)
- Testing
- Homeostasis-Enrichment-Plasticity (HEP®) Approach, Usual Care Group
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Medipol University
Labor, Premature
Routine Early vs Delayed Amniotomy for Preterm Pregnancies: A Randomized Open Label Trial
To compare the duration of preterm induction of labor in women undergoing early vs. late or no artificial rupture of membranes (AROM). Maternal and neonatal outcomes will also be compared between the two groups.
- Trial name
- Cereal (NCT03682822)
- Testing
- Early Artificial rupture of membranes, Delayed Artificial rupture of membranes
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- The University of Texas Health Science Center, Houston
Preterm Labor
A Phase 2 Study of OBE001 Versus Placebo in the Delay of Preterm Birth
The primary objective of this study is to assess the efficacy of a single dose of OBE001, an oral oxytocin antagonist, given for up to 7 days to delay preterm birth by 7 days compared to placebo.
- Trial name
- TERM (NCT02326142)
- Testing
- OBE001
- Where
- 23 sites in Belgium, Germany and 4 more
- Volunteers
- 10 people
- Sponsor
- ObsEva SA