Clinical trials: Delivery Outcomes
Cesarean Birth
The Cesarean Study: Optimizing Cesarean Sections and Improving Patient-Healthcare Provider Trust Using Evidence Informed Recommendations
Cesarean section (CS) rates have rapidly increased worldwide, with projections suggesting that by 2030, one in every three births will be by CS (1).
- Trial name
- CS (NCT07759622)
- Testing
- Cesarean Bundle
- Where
- Sweden
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Lund University
Cerclage, Cervical, Cervical Insufficiency
Long-Term Patient-Reported Maternal Outcomes Following Abdominal Cerclage for the Prevention of Preterm Birth
This study aims to explore the maternal patient reported outcomes on pelvic pain sexual health anxiety and depression bladder discomfort foreign body sensation trust in the cerclage, and how these parameters affect the general…
- Trial name
- NCT06875401
- Testing
- Abdominal cerclage (open or laparoscopic)
- Where
- Denmark
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Intact Cord Placental Delivery, Delayed Cord Clamping
Intact Cord Placental Delivery vs Delayed Cord Clamping
The management of the third stage of labour plays a critical role in neonatal transition. Uninterrupted Intact Cord Clamping (UICC), is a clinical approach where the umbilical cord remains unclamped until the placenta is…
- Conditions
- Intact Cord Placental Delivery, Delayed Cord Clamping, Standard Delayed Cord Clamping, Timing of Cord Clamping
- Trial name
- TTC (NCT07713277)
- Where
- Italy
- Volunteers
- 1,979 people, healthy volunteers welcome
- Sponsor
- Azienda ULSS 8 Berica
Preterm Infant, Umbilical Cord Milking
Effect of Intact Umbilical Cord Milking on Neonatal and First Year Neurodevelopmental Outcomes in Very Preterm Infants.
The investigators hypothesise that intact umbilical cord milking (I-UCM) will reduce neonatal morbidity and improve long term neurodevelopmental outcome in very preterm infants.
- Trial name
- Cord-milking (NCT03200301)
- Testing
- Intact Umbilical Cord Milking
- Where
- India
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jubilee Mission Medical College and Research Institute
Group B Streptococcus Carrier in Childbirth, Group B Streptococcal Infection, Late-Onset
Maternal, Neonatal and Infant Outcomes at Kawempe National Referral Hospital
Maternal immunisation is an evolving field that deserves special attention given its potential to have a significant positive impact on the health of women and children globally, and the potential safety and risk considerations…
- Conditions
- Group B Streptococcus Carrier in Childbirth, Group B Streptococcal Infection, Late-Onset, Group B Streptococcal Infection, Early-Onset, Group B Streptococcus Neonatal Sepsis
- Trial name
- PREPARE (NCT04653948)
- Where
- Uganda
- Volunteers
- 3,423 people, healthy volunteers welcome
- Sponsor
- St George's, University of London
Pregnancy, Birth
Effects of Online and App-Based Prenatal Yoga on Birth Outcomes
This randomized controlled trial evaluated the effects of a midwife-led digital prenatal yoga intervention via the MIDWIFEYOGA mobile application on birth and neonatal outcomes among 74 primiparous women.
- Conditions
- Pregnancy, Birth, Yoga
- Trial name
- NCT07880093
- Testing
- Online and App-Based Prenatal Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Vasviye Eroğlu
Breastfeeding, Skin to Skin Contact
Effect of Combined Skin-to-Skin Contact and Kangaroo Care on Breastfeeding and Bonding in Cesarean-Born Newborns
This randomized controlled study aims to evaluate the effect of consecutive skin-to-skin contact applied by the mother and father on breastfeeding parameters and parent-infant bonding in babies born by cesarean section.
- Conditions
- Breastfeeding, Skin to Skin Contact, Cesarean Birth, Kangaroo Care
- Trial name
- SSC-CS (NCT07410754)
- Testing
- Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Premature Neonate
Effect of "Kangaroo Mother Care" on Premature Infants Physiological Outcomes
This project aims at testing the effect of applying the KMC on the premature infants' physiological outcomes. The findings of this project are expected to contribute to the discipline of preterm infants' care by providing…
- Trial name
- NCT02919540
- Testing
- Kangaroo care approach
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Advanced Maternal Age Pregnancy, Premature
Pregnancies Outcomes in Advanced Maternal Age Women
Pregnancies occurring in advanced maternal age (AMA) have become more common over the last few decades for a variety of reasons.
- Conditions
- Advanced Maternal Age Pregnancy, Premature, Labor Complication, Delivery Complication
- Trial name
- POIAMA (NCT06528340)
- Testing
- spontaneous delivery
- Where
- Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Centro di Ricerca Clinica Salentino
Preterm Birth, Distress Respiratory Syndrome
Adverse Neonatal Outcomes With a Shortened Clinical Regimen of Dexamethasone.
Respiratory morbidity, including respiratory distress syndrome (RDS), is a serious complication of preterm birth and the leading cause of early neonatal mortality and disability.
- Trial name
- UNODEXA (NCT06569251)
- Testing
- Dexamethasone 12 mg QD, Dexamethasone 6 mg BID
- Where
- Honduras
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ricardo A Gutierrez Ramirez, MD, MSc, FACOG
Neonatal Death, Prematurity
Outcomes Following Early Parenteral Nutrition Use in Preterm Neonates
BACKGROUND An essential part of neonatal care is providing nutrition to ensure that babies grow and develop. Providing this can be difficult in premature babies because their intestines are underdeveloped.
- Trial name
- NCT03767634
- Testing
- Parenteral nutrition
- Where
- United Kingdom
- Volunteers
- 97,507 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Infertility, Microbiome
Frozen Embryo Transfer Pregnancy Outcomes Prediction by Microbiome
This study intends to explore the correlation between cervical microbiome, gut microbiome and pregnancy outcomes of frozen embryo transfer patients through a multicenter prospective observational study, and to explore the…
- Trial name
- NCT05521295
- Testing
- no intervention
- Where
- China
- Volunteers
- 3,600 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Infertility
Clinical Outcomes of Slow Developing Blastocysts
This study evaluates which transfer strategy will result in a higher probability of pregnancy in patients whose single best day 5 embryo resulting from an IVF cycle is classified as expansion grade <4 by Gardner and Schoolcraft…
- Trial name
- LATEBLOOM (NCT03360097)
- Testing
- Frozen Embryo Transfer
- Where
- Spain
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Fundacion Dexeus
The Aim of Our Study Was to Evaluate the Outcomes in Women Who Implemented the Enhanced Recovery After Surgery Protocol at Delivery by Cesarean Delivery
Implementation of Enhanced Recovery in Women Undergoing Cesarean Delivery
Aim: The aim of our study was to evaluate the outcomes in women who implemented the ERAS (Enhanced Recovery after Surgery) protocol at delivery by cesarean delivery(CD).
- Trial name
- ERAS (NCT05841888)
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ali Yavuzcan
Alcohol Use Disorder
Internet-delivered Therapy for Alcohol Misuse: Investigating Patient Preference for Self-guided or Guided Treatment
Internet-delivered cognitive behaviour therapy (ICBT) shows promise as a method of treating alcohol misuse. In this form of treatment, patients complete online lessons over several weeks that assist patients in developing skills…
- Trial name
- NCT04611854
- Testing
- Guidance, ICBT for alcohol misuse
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Regina
Bronchopulmonary Dysplasia (BPD), Chronic Lung Disease of Newborn
Long-Term Burden of BPD and Health-Related Quality of Life (BronQ Family)
The objective of this study is to examine the long-term impact of having a child with Bronchopulmonary Dysplasia (BPD) on the parents and caregivers from the time of diagnosis through adulthood.
- Conditions
- Bronchopulmonary Dysplasia (BPD), Chronic Lung Disease of Newborn, HRQOL (Health Related Quality Of Life)
- Trial name
- BronQ Family (NCT07134387)
- Testing
- N/A, no intervention, participation in survey
- Where
- Germany
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Global Foundation for the Care of Newborn Infants
Environmental Exposure, Fertility
JiGenerations Health Cohort Study：Parental Exposure and Intergenerational Health in China
The growing recognition of maternal health's impact on offspring necessitates large-scale prospective cohort studies spanning the maternal-child life cycle.
- Conditions
- Environmental Exposure, Fertility, Health Problems in Pregnancy, Adverse Pregnancy Outcomes
- Trial name
- NCT07514377
- Testing
- N/A (Observational Study)
- Where
- China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- National Research Institute for Family Planning, China
Sperm DNA Fragmentation, Sperm DNA Impact on ART Outcomes
Clinical Thresholds of Double-strand Breaks in Sperm's DNA in ART
The goal of this prospective observational study is to learn about the impact of double-strand sperm DNA fragmentation (dsSDF) on assisted reproductive technology (ART) outcomes and to derive clinically relevant threshold values…
- Trial name
- DSBs (NCT07621991)
- Testing
- LensHooke X12 Device
- Where
- 2 sites in India
- Volunteers
- 484 people, healthy volunteers welcome
- Sponsor
- Indira IVF Hospital Pvt Ltd
Preterm Birth, Developmental Delay
The Alkmaar MLPTI Cohort Study: Outcomes at 9 Years
Objective of the study: To examine cognition, motor function, executive functions, speech and language development, behaviour, psychosocial functioning,academic achievement, physical morbidities and growth of MLPTI at the age of…
- Conditions
- Preterm Birth, Developmental Delay, Growth Delay
- Trial name
- NCT05990582
- Testing
- CBCL, SDQ, CCC-2-NL
- Where
- Netherlands
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Noordwest Ziekenhuisgroep
Bacterial Vaginosis, Fetal Membranes, Premature Rupture
Perinatal Infections in Pakistan
There are large differences in health outcomes related to pregnancy and birth between developed and developing countries. This study will investigate how infections, medical history, health care behavior and psychosocial issues…
- Conditions
- Bacterial Vaginosis, Fetal Membranes, Premature Rupture, Chorioamnionitis, Pregnancy
- Trial name
- NCT00070746
- Where
- Pakistan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health