Clinical trials: Delivery Outcomes
Advanced Maternal Age Pregnancy, Premature
Pregnancies Outcomes in Advanced Maternal Age Women
Pregnancies occurring in advanced maternal age (AMA) have become more common over the last few decades for a variety of reasons.
- Conditions
- Advanced Maternal Age Pregnancy, Premature, Labor Complication, Delivery Complication
- Trial name
- POIAMA (NCT06528340)
- Testing
- spontaneous delivery
- Where
- Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Centro di Ricerca Clinica Salentino
Labor Pain, Anxiety
Breathing Exercises During Labor and Maternal Outcomes
This randomized controlled trial evaluated the effects of guided breathing exercises applied during labor on maternal stress, pain, anxiety, birth satisfaction, and labor outcomes.
- Conditions
- Labor Pain, Anxiety, Stress, Psychological
- Trial name
- NCT07566026
- Testing
- Guided Breathing Exercises During Labor
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Nilgun Avci
Infertility, Frozen Embryo Transfer (FET)
Platelet-Rich Plasma vs. Granulocyte Colony-Stimulating Factor vs. Placebo and Outcomes in Frozen Embryo Transfer
The goal of this clinical trial is to assess the impact of using Platelet-Rich Plasma (PRP) vs. Granulocyte Colony-Stimulating Factor (GCSF) vs.
- Trial name
- NCT03945812
- Testing
- Granulocyte Colony Stimulating Factor, Platelet Rich Plasma Arm, Saline
- Where
- Egypt
- Volunteers
- 665 people
- Sponsor
- Wael Elbanna Clinic
HIE - Hypoxic - Ischemic Encephalopathy, Perinatal Anoxic-ischemic Brain Injury
Biomarkers Study in Infants With Prior Neonatal Brain Injury
This research focuses on the long-term cognitive development of children, including healthy infants and those who had a perinatal brain injury.
- Conditions
- HIE - Hypoxic - Ischemic Encephalopathy, Perinatal Anoxic-ischemic Brain Injury, Premature Birth, Healthy Participants
- Trial name
- NCT07413900
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Infertility, Microbiome
Frozen Embryo Transfer Pregnancy Outcomes Prediction by Microbiome and Transcriptome
This study intends to explore the correlation between cervical microbiome, gut microbiome, transcriptome and pregnancy outcomes of frozen embryo transfer patients through a multicenter prospective observational study, and to…
- Trial name
- NCT05545631
- Testing
- no intervention
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shengjing Hospital
Pregnancy Related
Legacies and Futures: Measuring Roles of Resilience and Vulnerability in Pregnancy and Birth Outcomes
Pregnancy care typically assumes patients are heterosexual married women whose gender matches their assigned sex (i.e., cisgender), stigmatizing patients and creating limitations, blocking affirming care.
- Trial name
- NCT05365828
- Where
- 14 sites in United Kingdom
- Volunteers
- 945 people, healthy volunteers welcome
- Sponsor
- University College, London
Alcohol Use Disorder
Internet-delivered Therapy for Alcohol Misuse: Investigating Patient Preference for Self-guided or Guided Treatment
Internet-delivered cognitive behaviour therapy (ICBT) shows promise as a method of treating alcohol misuse. In this form of treatment, patients complete online lessons over several weeks that assist patients in developing skills…
- Trial name
- NCT04611854
- Testing
- Guidance, ICBT for alcohol misuse
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Regina
Pregnancy Outcome
The 3D Cohort Study (Design, Develop, Discover)
The 3D Cohort Study (Design, Develop, Discover) was established to help bridge knowledge gaps about the links between various adverse exposures during pregnancy with birth outcomes and later health outcomes in children.
- Trial name
- 3D (NCT03113331)
- Where
- Canada
- Volunteers
- 2,366 people
- Sponsor
- Université de Sherbrooke
Prematurity; Extreme, Prematurity
Breastfeeding Support and Promotion Program to Improve the Health of Premature Babies (PAP-LM)
This study evaluates the effectiveness of a breastfeeding support and promotion program to increase exclusive breastfeeding rates in the preterm group.
- Trial name
- PAP-LM (NCT06653595)
- Testing
- Programme to Support Breastfeeding
- Where
- 2 sites in Spain
- Volunteers
- 162 people
- Sponsor
- University of Barcelona
Severe Intra-uterine Growth Restriction, Preterm Birth
Impact of Early and Severe Fetal Growth Restriction on Neurodevelopmental Outcomes in Preterm Infants
Very early onset intra uterine growth restriction (IUGR) affects 5-10% of pregnancies and is the second leading cause of perinatal mortality.
- Conditions
- Severe Intra-uterine Growth Restriction, Preterm Birth, Neurodevelopmental Disorders, Placental Insufficiency
- Trial name
- NCT05381272
- Volunteers
- 20 people
- Sponsor
- Central Hospital, Nancy, France
Mild Birth Asphyxia, Moderate Birth Asphyxia
Olfactory Testing in Perinatal Asphyxia: Enhancing Risk Assessment
Neonatal asphyxia remains a leading cause of neurodevelopmental disabilities despite advancements in perinatal care. Hypoxic-ischemic encephalopathy (HIE), a severe outcome of asphyxia, impacts 1-3 infants per 1,000 live births…
- Trial name
- MEMOBRAIN (NCT06744244)
- Testing
- Olfactory Testing, Heart rate (HR), Heart Rate Variability (HRV), Respiratory Rate (RR), peripheral oxygen saturation (SpO2), Video-EEG
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Parma
Breast Cancer Early Stage Breast Cancer (Stage 1-3), Endocrine Therapy
Symptom Monitoring Using Patient-Report to Improve Medication Use
This is an intervention targeting patients at risk for non-adherence to endocrine therapy after primary treatments for hormone-positive breast cancer.
- Trial name
- SyMPTOM (NCT06765707)
- Testing
- Pharmacist delivered symptom monitoring and management
- Where
- 4 sites in United States
- Volunteers
- 225 people
- Sponsor
- Medical College of Wisconsin
HIV Infections, Pregnancy Complications
Trial of Vitamins Among Children of HIV-infected Women
The purpose of this study is to examine the effects of multivitamin (B, C, E) supplementation on reducing the risk of morbidity and mortality outcomes among children born to HIV positive mothers, compared to placebo…
- Trial name
- NCT00197730
- Testing
- Multivitamins - vitamins B complex, C and E
- Where
- Tanzania
- Volunteers
- 2,387 people
- Sponsor
- Harvard School of Public Health (HSPH)
Preterm Birth, Inadequate Milk Production
Milk Volume Outcomes Following Oral Nicotinamide Riboside Supplementation in Mothers of Extremely Preterm Infants
This study aims to evaluate the feasibility and effects of nicotinamide riboside (NR) supplementation in lactating mothers of infants expected to be hospitalized in the neonatal intensive care unit (NICU) for at least four weeks.
- Trial name
- MOONRISE (NCT04614714)
- Testing
- Nicotinamide Riboside (NR)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Embryo Transfer, Fertilization in Vitro
Does Sexual Intercourse Affect the Outcomes of Frozen-thawed Embryo Transfer?
The goal of this clinical trial is to test whether sexual intercourse the night after embryo transfer affects thawed embryo implantation rates.
- Conditions
- Embryo Transfer, Fertilization in Vitro, Coitus
- Trial name
- NCT06134609
- Testing
- Sexual intercourse
- Where
- Israel
- Volunteers
- 656 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Preterm Infant, Umbilical Cord Milking
Effect of Intact Umbilical Cord Milking on Neonatal and First Year Neurodevelopmental Outcomes in Very Preterm Infants.
The investigators hypothesise that intact umbilical cord milking (I-UCM) will reduce neonatal morbidity and improve long term neurodevelopmental outcome in very preterm infants.
- Trial name
- Cord-milking (NCT03200301)
- Testing
- Intact Umbilical Cord Milking
- Where
- India
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jubilee Mission Medical College and Research Institute
Genetic Predisposition
Genetic Counseling Service Delivery and Outcomes in Diverse and Underserved Populations
This 2-arm prospective, randomized, controlled clinical trial compared outcomes of telephone genetic counseling (intervention) versus in-person genetic counseling (control) in an underserved, multilingual patient population…
- Trial name
- NCT06212310
- Where
- United States
- Volunteers
- 419 people
- Sponsor
- University of Texas Southwestern Medical Center
Alcohol Misuse
Adaptive Actions and Alcohol Use Outcomes During Internet-delivered Cognitive Behaviour Therapy
This observational study investigates an Internet-delivered Cognitive Behaviour Therapy (ICBT) intervention for alcohol misuse, called the Alcohol Change Course Enhanced (ACCE).
- Trial name
- NCT07021053
- Testing
- Alcohol Change Course Enhanced
- Where
- Canada
- Volunteers
- 165 people
- Sponsor
- University of Regina
Infertility and Miscarriage
A Multicenter, Prospective, Randomized Controlled Clinical Study on the Effect of Hysteroscopic Uterine Septum Resection on IVF-ET Outcomes in Infertile Patients With Non-recurrent Miscarriage
This study aims to evaluate the impact of hysteroscopic transcervical resection of the septum (TCRS) on fertility in infertile women without recurrent miscarriage, primarily assessing its effect on subsequent IVF-ET outcomes.
- Trial name
- NCT07611656
- Testing
- Transcervical resection of septum
- Where
- China
- Volunteers
- 236 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Anterior Knee Pain Syndrome
10-year Follow-up After Tibial Tubercle Transposition
Patellofemoral pain is a common complaint especially in young adults. It can be caused by patellar maltracking. Part of this is a patella alta.
- Trial name
- TTTfollow-up (NCT05629754)
- Testing
- MRI, radiological assessment
- Where
- Netherlands
- Volunteers
- 32 people
- Sponsor
- Centre for Orthopaedic Research Alkmaar