Clinical trials: Delivery Outcomes
Premature Birth
Delayed Clamping and Milking the Umbilical Cord in Preterm Infants
This is a randomized controlled trial that will compare the effects of delayed umbilical cord clamping to umbilical cord milking in preterm infants (less than 34 weeks gestation).
- Trial name
- NCT02092103
- Testing
- Cord Milking
- Where
- United States
- Volunteers
- 282 people
- Sponsor
- TriHealth Inc.
Infertility, Donor Oocyte Assisted Reproduction
Fresh Versus Vitrified-Warmed Donor Oocytes: Embryological and Clinical Outcomes
This multicenter retrospective observational study compares embryological and clinical outcomes following treatment with fresh versus vitrified-warmed donor oocytes at Bocian Fertility Clinic centers in Poland.
- Trial name
- FRESH-FROZEN (NCT07904936)
- Testing
- Fresh Donor Oocyte ICSI, Vitrified-Warmed Donor Oocyte ICSI
- Where
- Poland
- Volunteers
- 3,000 people
- Sponsor
- Center for Reproductive Medicine Bocian
Infertility, Implantation Rate
Hyaluronan-enriched Medium and Euploid Blastocyst Transfers
It has been proposed that enriching transfer media with hyaluronan (EmbryoGlue medium) improves pregnancy outcomes compared with media containing lower concentrations of this molecule.
- Conditions
- Infertility, Implantation Rate, Clinical Pregnancy Rate, Live Birth Rate
- Trial name
- GluePloid (NCT06165367)
- Testing
- EmbryoGlue Medium
- Where
- United Arab Emirates
- Volunteers
- 783 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Childhood Disruptive Behavior Disorders, Oppositional Defiant Disorder
Child and Family Outcomes and Consumer Satisfaction for Online vs Staff-Delivered Parenting Intervention
This trial addresses a serious and all-too-frequent public health problem, namely early-onset disruptive behavior problems in young children.
- Conditions
- Childhood Disruptive Behavior Disorders, Oppositional Defiant Disorder, Conduct Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- TPAS (NCT02121431)
- Testing
- Triple P--Positive Parenting Program
- Where
- 2 sites in United States
- Volunteers
- 334 people
- Sponsor
- University of South Carolina
Pain, Postoperative, Cesarean Section
Post-operative Emesis and Pain Outcomes After Cesarean Delivery
Approximately 20% women who undergo cesarean delivery would suffer from severe post-operative pain, which may further increase their risks from developing postpartum depression.
- Conditions
- Pain, Postoperative, Cesarean Section, Nausea, Postoperative, Vomiting, Postoperative
- Trial name
- EPOC (NCT03645239)
- Testing
- Mechanical Temporal Summation assessment, Preoperative pain assessment, Questionnaires
- Where
- Singapore
- Volunteers
- 595 people
- Sponsor
- KK Women's and Children's Hospital
HIV
DSD Models at South Africa Sentinel Sites
Many countries in sub-Saharan Africa are rapidly scaling up "differentiated service delivery" (DSD) models for HIV treatment to improve the quality of care, increase access, reduce costs, and support the continued expansion and…
- Trial name
- SENTINEL 2 (NCT05886530)
- Testing
- No intervention
- Where
- South Africa
- Volunteers
- 15,520 people
- Sponsor
- Boston University
Preterm Infants, Stress
Effects of Bundled Supportive Interventions on Preterm Infants' Stress-Related Outcomes During Invasive Procedures
The proposed 2-year study has two specific aims: (1) to examine the effects of a "bundle" of supportive interventions on preterm infants' stress (salivary cortisol and dehydroepiandrosterone [DHEA] levels and physiological…
- Trial name
- NCT03010891
- Testing
- The bundle of supportive interventions, Usual NICU care
- Volunteers
- 66 people
- Sponsor
- National Defense Medical Center, Taiwan
Gastroschisis
Randomized Clinical Trial of Early Delivery in Fetal Gastroschisis vs. Routine Care
Primary objective: to test the hypothesis that elective early delivery will protect the fetal bowel from the deleterious intrauterine factors late in the pregnancy and will be associated with improved neonatal outcomes.
- Trial name
- NCT01884324
- Testing
- Early Delivery
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Baylor College of Medicine
Primary Maternal and Neonatal Outcomes; Assisted Reproductive Technology
Retrospective Comparison of Pregnancy Outcome of Infertile Patients After Fresh and Warmed Single Blastocyst Transfer From 2014 to 2018.
The investigators retrospectively analysed the maternal and neonatal outcomes following a single fresh blastocyst transfer and a single warmed blastocyst transfer from procedures performed between 2014 and 2018 in a tertiary…
- Trial name
- NCT04310761
- Testing
- one single blastocyst transfer, both fresh and warmed
- Volunteers
- 4,613 people
- Sponsor
- Istituto Clinico Humanitas
Pregnancy, Osteopathic Manipulative Treatment (OMT)
Osteopathic Manipulative Treatment in the Third Trimester of Pregnancy
Osteopathic Manipulative Therapy (OMT) is a hands-on approach to treating conditions that affect all areas of the body. Physicians trained in OMT (Doctors of Osteopathic Medicine or DO) use OMT to correct structural imbalances in…
- Trial name
- NCT06570395
- Testing
- Osteopathic Manipulative Treatment
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Corewell Health South
Infertility, Microbiome
Frozen Embryo Transfer Pregnancy Outcomes Prediction by Microbiome and Transcriptome
This study intends to explore the correlation between cervical microbiome, gut microbiome, transcriptome and pregnancy outcomes of frozen embryo transfer patients through a multicenter prospective observational study, and to…
- Trial name
- NCT05545631
- Testing
- no intervention
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shengjing Hospital
Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma
Evaluation of Barriers to Cancer Care Delivery and Outcomes for Women of Color With Metastatic Breast Cancer
This study evaluates disparities and barriers in cancer care delivery and outcomes in women of color by identifying socioeconomic variables that may be related to the inequity.
- Trial name
- NCT06206239
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Thomas Jefferson University
Weight Gain, Maternal; Diabetes Mellitus, Affecting Fetus
Tongji Maternal and Child Health Cohort
This is a population-based study to obtain data for the evaluation of current used recommendations for weight gain during pregnancy released by IOM (2007) and investigate the association between maternal diet and the health…
- Conditions
- Weight Gain, Maternal; Diabetes Mellitus, Affecting Fetus, Diet Habit, Pregnancy Complications
- Trial name
- TMCHC (NCT03099837)
- Volunteers
- 8,649 people
- Sponsor
- Huazhong University of Science and Technology
Preterm Birth
NICU-HEALTH (Hospital Exposures and Long-Term Health)
The purpose of this study is to evaluate the impact of environmental exposures during the NICU hospitalization on preterm infant development. The research team is interested in both chemical and non-chemical exposures.
- Trial name
- NCT01963065
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Twin Pregnancy, Preeclampsia
Low-dose Aspirin for Prevention of Adverse Pregnancy Outcomes in Twin Pregnancies
Twin pregnancies are associated with increased risk of perinatal adverse outcomes , including preeclampsia , fetal growth restriction , preterm premature rupture of membranes and preterm birth.
- Conditions
- Twin Pregnancy, Preeclampsia, Preterm Birth, Fetal Growth Restriction
- Trial name
- NCT04051567
- Testing
- Aspirin 100mg
- Where
- China
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Ministry of Science and Technology of the People´s Republic of China
Obstructive Sleep Apnea, Pregnancy Induced Hypertension
Sleep Quality in Pregnancy and Its Impact on Pregnancy Outcomes
Hypothesis:Sleep Disorders are very common during pregnancy but the their exact role in causation of pregnancy related disorders is yet to be determined.
- Conditions
- Obstructive Sleep Apnea, Pregnancy Induced Hypertension, High-Risk Pregnancy, Restless Leg Syndrome
- Trial name
- NCT02016638
- Testing
- Polysomnography and ambulatory blood pressure recording
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
Birth Defects
Effectiveness of Comprehensive Tertiary Interventions on Incidence and Clinical Outcomes of Birth Defects
This project is a single blind cluster randomized controlled trial with a purpose of assessing the effectiveness of a comprehensive tertiary interventions (before pregnancy, during pregnancy and after delivery) on the incidence…
- Trial name
- NCT03725878
- Testing
- Standard tertiary interventions of birth defects, Additional preconception health care, Additional health care procedures during and after pregnancy
- Where
- China
- Volunteers
- 4,808 people
- Sponsor
- Children's Hospital of Fudan University
Pregnancy Related, Umbilical Cord Issue
Association Between Blood Volume, the Interval From Delivery to Cord Clamping, and Number of Umbilical Cord Milking
Delayed umbilical cord clamping (DCC), usually 1-3 minutes, is reported to be beneficial for term and preterm infants. Nevertheless, there are reasons that urge us to reevaluate the effect of DCC.
- Conditions
- Pregnancy Related, Umbilical Cord Issue, Placental Transfusion
- Trial name
- NCT04898868
- Testing
- cord blood spontaneous drainage, Umbilical cord miking
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Maternal-Fetal Relations, Birth, First
Effects of Pelvic Exercises on Birth and Incontinence
The Effect of Pelvic Floor Exercises During Pregnancy on Obstetric Outcomes and Urinary Incontinence: A Prospective Randomized Controlled Trial
- Conditions
- Maternal-Fetal Relations, Birth, First, Incontinence, Urinary, Pelvic Floor Disorders
- Trial name
- NCT07268014
- Testing
- Pelvic Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Premature Birth
Prophylactic DR-CPAP on Late Preterm Infants Born by C-section: an RCT
A Pragmatic Randomized Controlled Pilot Trial to Evaluate the Impact of Early Prophylactic Continuous Positive Airway Pressure with or without Supplemental Oxygen in Spontaneously Breathing Late Preterm Newborn Infants Born by…
- Trial name
- PLANT (NCT05204719)
- Testing
- Prophylactic Delivery Room Continuous Positive Airway Pressure
- Where
- 5 sites in United States, Canada and 1 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma