Clinical trials: Delivery Outcomes
Endometriosis, Infertility
Endometrial Markers and Response of Endometriosis Patients to Prolonged GnRH Agonist Prior to IVF
This prospective randomized trial evaluates whether one can predict which infertile women with endometriosis who are candidates for in vitro fertilization will benefit from prolonged therapy with a GnRH agonist by the…
- Trial name
- IntegrinIVF (NCT00621179)
- Testing
- Leuprolide acetate in depot suspension, No intervention
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Colorado Center for Reproductive Medicine
Perinatal Outcomes
Can Safety Planning Improve Perinatal Outcomes Among Pregnant Women Exposed to Intimate Partner Violence?
OBJECTIVE: To investigate if, among women exposed to physical violence during pregnancy, does a targeted intervention consisting of safety planning and referral to community advocacy services decrease rates of adverse perinatal…
- Trial name
- NCT00831831
- Testing
- Safety planning
- Where
- Canada
- Sponsor
- University of British Columbia
Delivery Complication, Pregnancy Related
Cesarean Delivery Outcomes in Maternal Critical Care
Cesarean delivery in critically ill pregnant women, especially outside the operating room, is a rare but high-risk situation for both mother and fetus.
- Trial name
- CESAREA (NCT07759024)
- Volunteers
- 200 people
- Sponsor
- Société Française d'Anesthésie et de Réanimation
Low Birth Weight, Premature Birth
Comparison of Outcomes of Early Kangaroo Mother Care and Standard Method Care in Healthy Low Birth Weight Preterm Neonates at a Tertiary Care Hospital
The goal of this clinical trial is to learn whether early initiation of kangaroo mother care (KMC) can improve clinical outcomes in healthy low birth weight preterm neonates (gestational age 30-37 weeks, birth weight <2000 g).
- Conditions
- Low Birth Weight, Premature Birth, Preterm Infant
- Trial name
- NCT07259486
- Testing
- Kangaroo Mother Care, Standard Medical Care (SMC)
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- University of Health Sciences Lahore
Family Involvement/Empowerment, Family-centered Care
Effectiveness of Family-Integrated Newborn Care to Improve Outcomes for Preterm and Low-birth-weight Neonates
The goal of this quasi-experimental study is to learn if integrating family in newborn care units as a key partner can improve the outcomes of preterm and low-birth-weight neonates.
- Conditions
- Family Involvement/Empowerment, Family-centered Care, Intensive Care Units, Neonatal, Family Integrated Newborn Care
- Trial name
- FINC (NCT07364903)
- Testing
- Family Integrated Newborn Care, an intervention to integrate family in the care targeted their preterm and Low-birth weight neonates, Standard medical treatment
- Where
- 2 sites in Ethiopia
- Volunteers
- 1,020 people
- Sponsor
- Laerdal Foundation
Infertility, Assisted Reproductive Technology Outcomes
The Impact of Having a Tattoo on Fertility Treatment Outcome
Tattoos are increasingly common among women of reproductive age, yet their potential systemic inflammatory effects and impact on fertility treatment outcomes are unknown.
- Trial name
- NCT07405879
- Where
- Canada
- Volunteers
- 328 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Repeated IVF Failure
Follow-Up Of Pregnancies Established During Study NT-03 (Thrive-IVF Follow-Up)
The purpose of this study is to evaluate pregnancy, delivery, and neonatal outcomes in subjects who maintain ongoing clinical pregnancies through Week 10 of gestation in NT-03.
- Trial name
- Thrive-IVF F/U (NCT01978561)
- Testing
- Post dosing with NT100
- Volunteers
- 40 people
- Sponsor
- Nora Therapeutics, Inc.
Preterm Birth, Caffeine
Caffeine for Infants Born at 28 to 34 Weeks Receiving Respiratory Support
The goal of this pilot clinical trial is to test if it is possible to conduct a larger study on the use of caffeine in preterm infants who need help with their breathing.
- Conditions
- Preterm Birth, Caffeine, Neonatal Outcomes
- Trial name
- CARES-Pilot (NCT07456670)
- Testing
- Caffeine
- Where
- Canada
- Volunteers
- 62 people
- Sponsor
- Queen's University
Maternal Health, Infant Health
Using Advanced Data Systems to Improve Health in Early Life in Rural Nepal
The goal of this cluster randomized controlled trial is to study the effect of a mobile-phone based application used by pregnant women on maternal and newborn health indicators.
- Conditions
- Maternal Health, Infant Health, Institutional Delivery, Birth Preparedness and Complication Readiness
- Trial name
- CITH (NCT05697822)
- Testing
- Mobile Phone and Cloud-based Electronic Contact and Recording System
- Where
- Nepal
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Amit Arjyal
Infertility, Infertility, Female
GnRH Agonist at Embryo Transfer: IVF Outcomes
In ART (assisted reproductive technology) cycles, embryos are transferred to a woman's uterus after in-vitro fertilization (IVF) in a laboratory.
- Conditions
- Infertility, Infertility, Female, Infertility, Male
- Trial name
- GRAET (NCT03544073)
- Testing
- Saline Solution for Injection, Leuprolide Acetate
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maimonides Medical Center
Patent Ductus Arteriosus, Preterm Infant
Early Prediction of Spontaneous Patent Ductus Arteriosus (PDA) Closure and PDA-Associated Outcomes
Patent ductus arteriosus (PDA), very common in preterm infants, is the delayed closure of a fetal blood vessel that limits blood flow through the lungs.
- Conditions
- Patent Ductus Arteriosus, Preterm Infant, Bronchopulmonary Dysplasia, Neurodevelopmental Abnormality
- Trial name
- NCT03782610
- Where
- 4 sites in United States
- Volunteers
- 526 people
- Sponsor
- Nationwide Children's Hospital
Infertility, Aneuploidy
The Effect of Acupuncture on Pregnancy Rates in Women Undergoing in Vitro Fertilization With Preimplantation Genetic Screening
While IVF offers an effective treatment for infertility, a significant proportion of IVF cycles still result in failed implantation and early miscarriage.
- Trial name
- NCT03981120
- Testing
- Laser and Traditional Acupuncture
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Breast Neoplasm
A Guided Internet-delivered Individually-tailored ACT-influenced CBT Intervention to Improve Psychosocial Outcomes in Breast Cancer
Background: Internet-delivered interventions (IDI) can provide remarkable opportunities in addressing breast cancer (BC) survivors' unmet needs, as they present an effective strategy to improve care coordination and provide…
- Trial name
- INNOVBC (NCT03275727)
- Testing
- iACT-BC
- Volunteers
- 128 people
- Sponsor
- Linkoeping University
Pregnancy
The Effect of Birth Plans on Obstetrical Outcomes
The study design is a prospective, single institution, randomized control trial in which the introduction of a birth plan is the intervention and a comparison of the rate of Caesarean sections between participants in the control…
- Trial name
- NCT02526459
- Testing
- Birth plan
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Saskatchewan Health Authority - Regina Area
Intrapartum Fetal Distress, Neonatal Asphyxia
Oral Sildenafil Citrate to Improve Maternal and Neonatal Outcomes in Low-resource Settings
The goal of this feasibility pilot clinical trial is to determine if sildenafil citrate 50mg orally, up to three times during labor, can: 1) reduce perinatal mortality and/or bag and mask ventilation at birth in planned vaginal…
- Conditions
- Intrapartum Fetal Distress, Neonatal Asphyxia, Intrapartum Asphyxia, Instrumental Delivery; Affecting Fetus
- Trial name
- NCT06522854
- Testing
- Sildenafil 50 mg Oral Tablet
- Where
- 4 sites in Nigeria
- Sponsor
- University of Alabama at Birmingham
IVF Outcomes
Comparison of Two Protocols in Frozen Embryo Transfer
This randomized clinical trial evaluates two different endometrial preparation protocols-hormone replacement therapy (HRT) and natural cycle-for frozen embryo transfer (FET) in infertile women undergoing assisted reproductive…
- Trial name
- NCT07003373
- Testing
- hormone replacement therapy (HRT) group
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Malihe Mahmoudinia
Preterm, Sensory Disorders
Evaluation of The Effectiveness of The SAFE Early Intervention Program
In this study, it was aimed to examine the effect of SAFE, which is a sensory-based, activity-oriented early intervention approach applied in an enriched environment with family cooperation, on cognitive, language, motor and…
- Conditions
- Preterm, Sensory Disorders, Cerebral Palsy
- Trial name
- NCT06930482
- Testing
- Safe early intervention, early intervention approach based on neurodevelopmental treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Gazi University
Stroke
Berlin PRehospital Or Usual Delivery of Acute Stroke Care
Prehospital stroke care in specialized ambulances increases thrombolysis rates, reduces alarm-to-treatment times, and improves prehospital triage. Preliminary analyses suggest cost-effectiveness.
- Trial name
- B_PROUD (NCT02869386)
- Testing
- STEMO, Regular care
- Where
- Germany
- Volunteers
- 1,500 people
- Sponsor
- Charite University, Berlin, Germany
Labor and Delivery
Role of the WHO Labour Care Guide in Improving Maternal and Fetal Outcomes
The goal of this randomized controlled trial is to compare the effectiveness of WHO labour care guide (LCG) with the WHO modified partogragh in improving the maternal and fetal outcomes among primigravida and multigravida in…
- Trial name
- NCT07445373
- Testing
- Group A (Intervention Arm): Monitoring with WHO Labour Care Guide), Group B (Control Arm): Monitoring with Standard WHO Partograph)
- Where
- Pakistan
- Volunteers
- 114 people
- Sponsor
- Khyber Teaching Hospital
Hepatitis C, Medication Adherence
Intensive Models of HCV Care for Injection Drug Users
Injection drug users (IDUs) constitute 60% of the approximately 5 million people in the U.S. infected with hepatitis C virus (HCV). HCV treatment leading to sustained viral response (SVR) is associated with increased survival.
- Trial name
- NCT01857245
- Testing
- Intensive Models (mDOT and CGT) of HCV Care
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Prisma Health-Upstate