Clinical trials: Delivery Outcomes
Morbid Obesity, Cesarean Section Complications
Anesthetic and Obstetric Outcomes in Morbidly Obese Pregnancy and Cesarean Delivery
Given that morbid obesity has been strongly associated with obstetric, neonatal and anesthetic complications, and that scarce reports have evaluated anesthetic and obstetric outcomes after cesarean delivery in morbidly obese…
- Conditions
- Morbid Obesity, Cesarean Section Complications, Pregnancy Related
- Trial name
- NCT03590951
- Testing
- Retrospective chart review
- Where
- United States
- Volunteers
- 771 people
- Sponsor
- Augusta University
Overweight and Obesity
The Effect of Vitamin D Supplementation in Overweight and Obese Pregnant Women
To understand the role of vitamin D supplementation on pregnancy outcomes and metabolic status in overweight and obese pregnant women.
- Trial name
- NCT04841265
- Testing
- Vitamin D3
- Where
- Singapore
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Type 1 Diabetes
Effectiveness of Empagliflozin Added to Automated Insulin Delivery (AID) Systems in Adults With Type 1 Diabetes With Sub-optimal Glycemic Outcomes
The goal of this 26-week multicenter, randomized, parallel, placebo-controlled trial is to test the effectiveness of empagliflozin use in conjunction with automated insulin delivery (AID) to improve glucose control in individuals…
- Trial name
- NCT06021145
- Testing
- Empagliflozin
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Poor Response to Ovulation Induction, Infertility, Female
Optimal Embryonic Stage for Transfer in Poor Responders
A Prospective cohort study including couples with poor responder females who undergoing ICSI
- Trial name
- NCT04485819
- Testing
- Cleavage stage transfer, Blast stage transfer
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Ganin Fertility Center
Doula Support, Postpartum
The Goal is to Examine the Impact of Doula-delivered, Nurse-coordinated Postpartum Care Among Individuals With Preterm Births <34 Weeks' Gestation Requiring NICU Admission.
The primary objective of this research is to conduct a randomized clinical trial to examine the impact of nurse-coordinated, doula-delivered postpartum support (intervention arm) on postpartum health care utilization, health…
- Conditions
- Doula Support, Postpartum, Postpartum Depression (PPD), Postpartum Anemia
- Trial name
- NEST (NCT07787845)
- Testing
- Doula-delivered, Nurse-coordinated postpartum support
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- University of South Carolina
Infertility
The Effects of Intrauterine Infusion of hCG at the Time of Embryo Transfer
The purpose of this study is to determine whether intrauterine hCG can improve the implantation rate and clinical pregnancy rate after embryo transfer in IVF/ICSI cycle.
- Trial name
- NCT02668965
- Testing
- Intrauterine hCG (pregnyl)
- Where
- Thailand
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Peripheral Artery Disease, Critical Limb Ischemia
Temsirolimus Adventitial Delivery to Improve ANGioplasty and/or Atherectomy Revascularization Outcomes Below the Knee
A multicenter, randomized, double-blind, placebo-controlled trial to evaluate the effect of Temsirolimus Perivascular Injection 0.1 mg/mL on the incidence of ischemia-driven major amputation, clinically driven target lesion…
- Trial name
- TANGO-3 (NCT04433572)
- Testing
- Temsirolimus
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Mercator MedSystems, Inc.
IUCD Complication
Vaginal Isonicotinic Acid Hydrazide Administration Prior to Insertion Levonorgestrel-releasing Intrauterine System
To investigate whether vaginal isonicotinic acid hydrazide (INH) administered before the levonorgestrel-releasing intrauterine system(IUs) insertion reduces failed insertions, insertion-related complications, and pain in Women…
- Trial name
- NCT04500028
- Testing
- INH
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Aswan University Hospital
Hemophilia A
Phase 3 Study for Efficacy and Safety Outcomes Data in Japanese Patients With Severe Hemophilia A
This Phase III clinical study will evaluate the safety and effectiveness of valoctocogene roxaparvovec in Japanese patients with severe hemophilia A.
- Trial name
- GENEr8-JPN (NCT06224907)
- Testing
- Valoctocogene roxaparvovec
- Where
- 4 sites in Japan
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- BioMarin Pharmaceutical
Delivery Complication, Delivery Problem
Delivery Outcomes by AIDA (Artificial Intelligence Dystocia Algorithm) Analysis
Aims: Primary aim is to investigate outcomes of eutocic labor, evaluating intrapartum ultrasound parameters by AIDA method: Angle of progression (AoP), Asynclitism degree (AD), fetal head-symphysis distance (HSD), and midline…
- Conditions
- Delivery Complication, Delivery Problem, Delivery; Injury, Delivery; Injury, Maternal
- Trial name
- AIDA (NCT06664112)
- Testing
- AIDA Analysis
- Where
- 2 sites in Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Centro di Ricerca Clinica Salentino
Preterm Infant Development, Preterm Infant Feeding Outcomes
Estimation of Nutritional Needs of Preterm Neonates Fed on Parenteral Nutrition and Effects on Body Weight Gain
This randomized controlled trial included 100 preterm and small for gestational age neonates. The study aimed to determine the optimal approach for estimating nutritional needs in parenteral nutrition (PN) with the assistance of…
- Trial name
- NCT07236957
- Testing
- Intervention Group, Control group
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Panos Papandreou
Prenatal Care, Food Insecurity
Impact of Food Insecurity on Utilization of Maternal Healthcare Services and Birth Outcomes in Slums in Pune, India
The goal of this observational study is to assess household food insecurity among slum-dwelling women in India and to explore if household food insecurity is associated with utilization of maternal healthcare services, birth…
- Conditions
- Prenatal Care, Food Insecurity, Pregnancy Outcome
- Trial name
- MCH (NCT06313112)
- Testing
- Observational study
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hirabai Cowasji Jehangir Medical Research Institute
Cervical Spinal Cord Injury
Comparing Outcomes of Elbow Extension Tendon Transfers
Active elbow extension has significant functional benefits for individuals with tetraplegia. The proposed work will provide information to assess how effectively people are using their elbow extension tendon transfers, and…
- Trial name
- NCT01204736
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- VA Office of Research and Development
Morbidity;Perinatal, Pregnancy Complications
Postpartum Outcomes in BC
For every case of maternal death, many more women experience life-threatening complications during pregnancy and childbirth. Yet, severe maternal morbidity (SMM) cases are often overlooked post-delivery.
- Conditions
- Morbidity;Perinatal, Pregnancy Complications, Pregnancy Related
- Trial name
- NCT05461183
- Testing
- Retrospective database analysis
- Volunteers
- 15,000 people
- Sponsor
- University of British Columbia
Diabetes, Gestational, Dietary Modification
Dietary Management of Gestational Diabetes
eMOM is a randomized, controlled trial to compare the effects of two different dietary interventions during pregnancy. The comparison is based on tissue glucose content (using continuous glucose monitoring system) in pregnant…
- Conditions
- Diabetes, Gestational, Dietary Modification, Glucose Intolerance During Pregnancy, Body Composition
- Trial name
- eMOM (NCT03681054)
- Testing
- Carbohydrate restricted diet, Plant-protein based diet
- Where
- Finland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Pregnancy, Pregnancy Complications
Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be
Forty percent of pregnant women in the United States are women who have never given birth. As a group, they sometimes have complications with their pregnancy, but there is no information from a previous pregnancy to identify who…
- Trial name
- nuMoM2b (NCT01322529)
- Where
- 17 sites in United States
- Volunteers
- 10,038 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Psychiatric Disorder, Depression
Investigating Neural Response Variability as a Single-patient Predictor of Successful CBT in Clinical Psychiatry
Many psychiatric patients are not sufficiently improved by current interventions. Functional magnetic imaging brain imaging (fMRI) has proven to be a promising method for predicting treatment outcomes in psychiatric treatment.
- Conditions
- Psychiatric Disorder, Depression, Anxiety Disorders, Insomnia
- Trial name
- TreVar (NCT04191811)
- Testing
- Internet-delivered cognitive behavioral therapy for major depressive disorder, Internet-delivered cognitive behavioral therapy for insomnia, Internet-delivered cognitive behavioral therapy for social anxiety disorder
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Anticoagulation, Thromboembolism
Comparison of Patient Outcomes Using Different Delivery Models of Anticoagulation Care
Hypothesis: Does the time spent within the target INR range differ when patients are managed by AMD or IT models of anticoagulation care? Experimental Design: The 36-month trial enrolled 192 eligible patients currently receiving…
- Trial name
- NCT00205400
- Testing
- medical care delivery model
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- University of Wisconsin, Madison
Type 1 Diabetes
Technology-delivered Physical Activity Program for Adolescents With Type 1 Diabetes
This project is comprised of a two-arm randomized control trial (RCT) testing the feasibility, acceptability, and preliminary efficacy of a nationally scalable program, Activate, a 12-week, technology-delivered diabetes…
- Trial name
- Activate (NCT05319600)
- Testing
- Diabetes behavior change skills training, Physical activity promotion program
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Vermont
Natural Childbirth, Water Birth
Effectiveness and Safety in Maternal and Neonatal Outcomes in Water Birth.
Childbirth is a unique and non-transferable experience in the life of a woman, her partner and her family. It is a very intense process that requires accompaniment and, in the vast majority of cases, requires analgesic support in…
- Conditions
- Natural Childbirth, Water Birth, Neonatal Asphyxia, Outcome, Adverse Birth
- Trial name
- NCT06429111
- Testing
- Epidural analgesia, Immersion water
- Where
- Spain
- Volunteers
- 642 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana