Clinical trials: Delivery Outcomes
Pregnancy, Maternal Anemia
Better Birth Outcomes Through Technology, Education, and Reporting
This is a pragmatic randomized control trial to evaluate the BETTER intervention compared to standard obstetrical care (control) to determine whether it helps to reduce maternal anemia and other adverse pregnancy outcomes.
- Conditions
- Pregnancy, Maternal Anemia, Pre-Term Birth, Hypertensive Disorders
- Trial name
- BETTER (NCT06261398)
- Testing
- BETTER: motivational interviewing and text messaging, Standard of care
- Where
- 3 sites in United States
- Volunteers
- 550 people
- Sponsor
- Ohio State University
Spontaneous Labor
Impact of Medjool Date Consumption on Labor and Delivery Outcomes
The proposed Medjool date randomized trial will help inform clinical practice regarding the utility of Medjool date consumption for labor onset by comparing the incidence of spontaneous labor with the need for labor induction in…
- Trial name
- Yumi Dates (NCT07058792)
- Testing
- Medjool dates
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The Cleveland Clinic
Pregnancy Complicated by Cardiovascular Disorders as Postpartum Condition, Delivered During Previous Episode, Breathing-Related Sleep Disorder
nuMoM2b Heart Health Study
This study is looking at the relationship between experiences during pregnancy and cardiovascular health 2 to 3½ years later. The investigators are recruiting women from the approximately 10,000 women who were enrolled and…
- Trial name
- nuMoM2b-HHS (NCT02231398)
- Where
- 15 sites in United States
- Volunteers
- 4,509 people
- Sponsor
- RTI International
Perioperative Hypothermia, Maternal Hypothermia
Perioperative Forced-Air Warming During Elective Cesarean Delivery Under Spinal Anesthesia
Intraoperative hypothermia is common during cesarean delivery under spinal anesthesia and contributes to maternal discomfort, shivering, and metabolic stress.
- Trial name
- FAM (NCT07757009)
- Testing
- Forced-Air Warming
- Where
- Qatar
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Pregnancy Rates
The Effect of Vaginal Speculum Type and Retention Time on Pregnancy Outcomes During The Embryo Transfer Process
Investigators aim to investigate possible affects of a speculum material and retention strategy on IVF pregnancy results. The study is planned as a prospective, randomized control trial.
- Trial name
- Speculum (NCT06619379)
- Testing
- Retention time of speculum
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Eurofertil IVF Health Center
This Study Aims to Provide Evidence on Which Positioning Strategy Offers the Best Hemodynamic Outcomes, Maternal Hemodynamic
Comparison of Maternal Hemodynamics During Spinal Anesthesia with Different Cesarean Delivery Positioning
Cesarean delivery is a common surgical procedure, and maintaining maternal hemodynamic stability during the procedure is crucial for both maternal and fetal outcomes .
- Conditions
- This Study Aims to Provide Evidence on Which Positioning Strategy Offers the Best Hemodynamic Outcomes, Maternal Hemodynamic, Maternal Positioning During CS
- Trial name
- NCT06857162
- Testing
- Positioninng during Cs
- Where
- Egypt
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Aswan University
Pregnancy, Neonatal Hearing Function
Comparison of Different Anesthetic Techniques on Hearing Outcomes in Neonates After Cesarean Delivery
This is a single-center, prospective, single-blind randomized controlled trial. The investigators plan to recruit 144 pregnant women scheduled for cesarean delivery.
- Trial name
- ATHNCD (NCT07852624)
- Testing
- Combined spinal-epidural anesthesia, General Anesthesia (GA)
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Endometriosis
Perinatal Consequences of Endometriosis
Endometriosis is a benign gynecological disease, characterized by the presence of endometrium-like tissue outside the uterine cavity that affect up to 10-15% of women in reproductive age worldwide, with an extensive impact on…
- Trial name
- ENDOBST (NCT02498691)
- Testing
- Biological collection
- Where
- France
- Volunteers
- 1,444 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Preterm Birth
Impact of Pessary Treatment on Cervical Stiffness Measurement and Birth Outcomes in Patients at Risk for Preterm Birth
Background: A preterm birth remain a worldwide important socioeconomic burden since prematurity has been consistently implicated in a wide range of health medical problems affecting newborn child and contributed in up to more…
- Trial name
- NCT05267717
- Testing
- Non-interventional study, all patients being tested with AG Pregnolia System to assess the values of the Cervical Stiffness
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Asklepios proresearch
Diabetes Mellitus, Type 1
The Impact of Hybrid Closed-loop Insulin Delivery in Type 1 Diabetes on Glycemic Control and PROMs
Since February 2019 the first hybrid closed-loop insulin pump, the Medtronic MiniMed 670G system, has been offered to people with type 1 diabetes in Belgium.
- Trial name
- INRANGE (NCT04414280)
- Testing
- Medtronic MiniMed 670G, Medtronic MiniMed 780G, Tandem Control-IQ
- Where
- 38 sites in Belgium
- Volunteers
- 1,600 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Respiratory Syncytial Virus (RSV)
Evaluating ABRYSVO Maternal Vaccine Effectiveness Among Infants
To generate critical evidence to support vaccine policy and implementation, Pfizer will collaborate with Kaiser Permanente Northern California (KPNC) to study the vaccine effectiveness (VE) of ABRYSVO vaccination during pregnancy…
- Trial name
- NCT07249320
- Testing
- ABRYSVO
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Pfizer
Infertility
Study Comparing Outcomes Between Conventional IVF and a "Freeze-all"-Strategy in Assisted Reproductive Technology
The purpose of this study is to compare conventional fresh embryo transfer with a "freeze all and transfer later strategy" in assisted reproductive technology in terms of ongoing pregnancy rates, live birth rates as well as…
- Trial name
- NCT02746562
- Testing
- Freeze all
- Where
- 2 sites in Denmark
- Volunteers
- 424 people
- Sponsor
- Anja Bisgaard Pinborg
Liver Diseases, Alcohol Use Disorder
Coronavirus Disease 2019 (Covid-19) Impact on Alcohol-related Liver Disease Patient Outcomes, Care and Alcohol Use
The study consists of a randomized controlled trial evaluating the efficacy and feasibility of a stepped alcohol treatment using telemedicine on unhealthy alcohol use in patients with chronic liver disease receiving care in…
- Trial name
- NCT05191446
- Testing
- Stepped alcohol intervention (SAT) to reduce unhealthy alcohol use, Usual Care (UC)
- Where
- 2 sites in United States
- Volunteers
- 180 people
- Sponsor
- University of California, San Francisco
Infertility
The Clinical Outcomes Following Transfer of Blastocysts Cultured From Thawed Cleavage Stage Embryos
Recent improvements in cell culture systems have led to a shift in in vitro fertilization (IVF) practice from early cleavage stage embryo transfer (ET) to blastocyst transfer.
- Trial name
- NCT02681029
- Testing
- Blastocyte Transferring, Embryo Transferring
- Where
- Iran
- Volunteers
- 220 people
- Sponsor
- Royan Institute
Metabolic Syndrome, Pregnant Women
Progression of Metabolic Syndrome Components During Pregnancy
The goal of this cohort study is to investigate the underlying risk factors to develop metabolic syndrome (MetS) during pregnancy, and the associations of MetS and its indicators with birth outcomes in southwest Ethiopia.
- Conditions
- Metabolic Syndrome, Pregnant Women, Birth Outcomes, Dietary Habits
- Trial name
- MetS_Preg (NCT05935904)
- Testing
- Exposure, Non exposure
- Where
- Ethiopia
- Volunteers
- 526 people, healthy volunteers welcome
- Sponsor
- University Ghent
Prematurity; Extreme, Prematurity; Decision Support
Health-Related Quality-of-Life and Household Financial and Wellbeing Impacts of Prematurity and Necrotising Enterocolitis (NEC).
PREM-IMPACT is a UK-based observational study exploring how caring for a very premature baby-particularly one affected by necrotising enterocolitis (NEC)-impacts families over the first year after hospital discharge.
- Conditions
- Prematurity; Extreme, Prematurity; Decision Support, Necrotising Enterocolitis, Preterm
- Trial name
- PREM-IMPACT (NCT07192393)
- Where
- 7 sites in United Kingdom
- Volunteers
- 90 people
- Sponsor
- Imperial College London
Emergencies, Injuries
The Impact of First Aid Blended Learning Training on Learning Outcomes and Helping Behaviour of Adult Laypeople in Rwanda
The goal of this study is to assess the impact of a first aid training delivered through a blended learning approach on learning outcomes and helping behaviour in adult laypeople in Rwanda.
- Conditions
- Emergencies, Injuries, Illness Physical
- Trial name
- NCT06003504
- Testing
- First aid training with blended learning approach, First aid training with face-to-face approach
- Where
- Rwanda
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Centre for Evidence-Based Practice, Belgium
Alcohol Use Disorder
Learning and Relapse Risk in Alcohol Dependence (FP2)
The investigators will examine clinical alterations in learning and automated approach behaviour and their neurobiological correlates in alcohol-dependent patients and healthy social drinkers and assess whether they are affected…
- Trial name
- LeAD_FP2 (NCT02615977)
- Testing
- Zooming Joystick Task
- Where
- 3 sites in Germany
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma
Evaluation of Barriers to Cancer Care Delivery and Outcomes for Women of Color With Metastatic Breast Cancer
This study evaluates disparities and barriers in cancer care delivery and outcomes in women of color by identifying socioeconomic variables that may be related to the inequity.
- Trial name
- NCT06206239
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Thomas Jefferson University
Pregnancy Complications, Delivery;Abnormal;Stillbirth
Obstetric Outcomes After Transvaginal Specimen Extraction in Gynecological Laparoscopy
One of the most important downsides of endoscopic surgery is the need to remove surgical specimens of different sizes through very small incisions.
- Trial name
- OUTSET-1 (NCT03439956)
- Testing
- Transvaginal specimen extraction
- Volunteers
- 200 people
- Sponsor
- Università degli Studi dell'Insubria