Clinical trials: Delivery Uterine
Cesarean Section Complications, Postpartum Hemorrhage
The Comparison of the Effect of Different Oxytocin Administrations on the Blood Loss During Cesarean Delivery
This study compares the effect of starting intravenous oxytocin infusion early before uterine incision versus late after umbilical cord clamping on the blood loss during elective cesarean section
- Conditions
- Cesarean Section Complications, Postpartum Hemorrhage, Blood Loss, Surgical, Blood Loss, Postoperative
- Trial name
- NCT03967171
- Testing
- before uterine incision oxytocin, after clamping the umbilical cord oxytocin
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Postpartum Hemorrhage
Administration Of Calcium Gluconate for The Reduction of Blood Loss During Vaginal Delivery
Postpartum hemorrhage is one of the leading causes of maternal morbidity following childbirth. Even when excessive bleeding is not clinically recognized, some women experience a significant decrease in hemoglobin levels after…
- Trial name
- NCT07714902
- Testing
- calcium gluconate
- Where
- Israel
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Preterm Delivery, Short Cervix
PREGNANT Short Cervix Trial
The purpose of this research study is to evaluate the usefulness of progesterone vaginal gel in decreasing the preterm birth rate in a population of pregnant women with short cervical length and at high risk for preterm birth.
- Conditions
- Preterm Delivery, Short Cervix, Short Uterine Cervical Length
- Trial name
- NCT00615550
- Testing
- progesterone
- Where
- 49 sites in United States, Belarus and 8 more
- Volunteers
- 465 people, healthy volunteers welcome
- Sponsor
- Juniper Pharmaceuticals, Inc.
Postpartum Hemorrhage, Cesarean Section Complications
Tranexamic Acid in Patients for Caesarian Delivery.
This is a prospective, double-blinded, randomized placebo-controlled trial. The study will be approved by the DUHS institutional review board (IRB) and the trial will be registered at clinical trial registry.
- Conditions
- Postpartum Hemorrhage, Cesarean Section Complications, Obstetric Anesthesia Problems
- Trial name
- TXA; CD (NCT05759156)
- Testing
- Tranexamic acid injection
- Where
- Pakistan
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Cervical Insufficiency
Patient Attitudes Toward Ultrasound Measurement of Cervical Length
The investigators propose a prospective evaluation of methods to assess cervical length for uncomplicated singleton gestations between 18-28 weeks presenting to the MFM office for routine mid pregnancy ultrasound.
- Trial name
- TVUS (NCT01482039)
- Testing
- Sequential ultrasound, Transvaginal ultrasound
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Intermountain Women and Children's Research
Cesarean Section Complications
Topical Tranexamic Acid Plus Bilateral Uterine Artery Ligation During Cesarean Delivery
Placenta previa (PP) is an obstetric condition that is closely linked with massive obstetric hemorrhage with a varied incidence about once in every 200 live births.
- Trial name
- NCT03741075
- Testing
- BUA, topical tranexamic acid
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aswan University Hospital
Uterine Niche, Closure; Incomplete, Uterus
Comparison the Effect of Uterine Closure Technique Difference on Uterine Niche After Caesarean Delivery.
Caesarean section scar may have result as isthmocele or scar detachment during pregnancy which is in few years after previous delivery.
- Trial name
- NCT04799457
- Testing
- Suture technique
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Healthy Participants
Rate of Tranexamic Acid Administration on Blood Pressure (RateTXA) Study.
Tranexamic acid is a well-established treatment for post-partum hemorrhage. This study aims to examine the effect of tranexamic acid administration rates on blood pressure changes over 1 minute compared to 10 minutes in healthy…
- Trial name
- RateTXA (NCT06356948)
- Testing
- Tranexamic Acid (TXA)
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Fetal Membranes, Premature Rupture, Premature Birth
The Use of Cranberries in Women With Preterm Premature Rupture of Membranes
Cranberries have been proved to reduce the rate of urinary tract infections in a population of women with recurrent urinary tract infections in previous studies.
- Trial name
- NCT00247104
- Testing
- Cranberries - Vaccinium macrocarpon
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Hyperglycemia, Pregnancy
The Extension of HAPO Follow-up Study
The prevalence of diabetes mellitus (DM) and cardiovascular disease (CVD) escalate remarkably worldwide and obesity becomes an epidemic disease.
- Conditions
- Hyperglycemia, Pregnancy, Overnutrition, Maternal Obesity During Childbirth
- Trial name
- NCT05477511
- Where
- Hong Kong
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Intact Cord Placental Delivery, Delayed Cord Clamping
Intact Cord Placental Delivery vs Delayed Cord Clamping
The management of the third stage of labour plays a critical role in neonatal transition. Uninterrupted Intact Cord Clamping (UICC), is a clinical approach where the umbilical cord remains unclamped until the placenta is…
- Conditions
- Intact Cord Placental Delivery, Delayed Cord Clamping, Standard Delayed Cord Clamping, Timing of Cord Clamping
- Trial name
- TTC (NCT07713277)
- Where
- Italy
- Volunteers
- 1,979 people, healthy volunteers welcome
- Sponsor
- Azienda ULSS 8 Berica
Cesarean Wound Repair
Extra - Abdominal Versus Intra - Abdominal Repair of the Uterine Incision at Cesarean Section
To evaluate the effects of extra-abdominal repair of the uterine incision compared to intra-abdominal repair, and to study is there superiority of one technique over the other in terms of primary outcomes - operative( up to 4…
- Trial name
- EKAM (NCT02373501)
- Testing
- Intra-abdominal repair, Extra-abdominal repair
- Where
- Israel
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Infant, Newborn, Infant, Low Birth Weight
In Utero Magnesium Sulfate Exposure: Effects on Extremely-Low-Birth-Weight Infants
This study examined the effect of magnesium sulfate (MgSO4) exposure on adverse outcome in extremely low birth weight (ELBW) infants.
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- MgSO4 (NCT01203501)
- Where
- 15 sites in United States
- Volunteers
- 1,339 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
Postpartum Hemorrhage
Oxytocin Maintenance Infusion in Labouring Women Undergoing Cesarean Delivery: an Up-down Sequential Allocation Study
This study is designed to determine the minimal effective oxytocin maintenance infusion required in labouring women undergoing cesarean delivery to achieve the best effect.
- Trial name
- NCT05290129
- Testing
- Oxytocin
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Uterine Bleeding Profile Prediction
A Study to Learn More About How a Smartphone App Called MyIUS Predicts Future Menstrual Bleeding in Women After They Have Begun Using Intrauterine Birth Control Method (a Birth Control Device is Inserted Into a Woman's Uterus by Her Doctor)
Researchers are looking to learn more about future menstrual bleeding in women who have started using intrauterine contraception methods.
- Trial name
- MyIUS (NCT04989595)
- Testing
- MyIUS app
- Where
- 6 sites in Brazil, Denmark and 4 more
- Volunteers
- 3,045 people, healthy volunteers welcome
- Sponsor
- Bayer
Episiotomy Wound, Anemia
Use of Tranexamic Acid After Vaginal Delivery with Episiotomy a RCT Placebo Control Trail
The objective of this study is to assess the effect of TA treatment on decline in Hb levels following vaginal delivery with an episiotomy, compared to a control group not receiving TA.
- Conditions
- Episiotomy Wound, Anemia, Early Postpartum Hemorrhage, Hemoglobin
- Trial name
- NCT05448456
- Testing
- Tranexamic acid
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assuta Ashdod Hospital
Preterm Birth
Preventing Preterm Birth With a Pessary
The primary objective of this study, is to determine the effect of a Cup pessary, a device that is currently readily available in the USA and similar in design to the Arabin pessary, on the incidence of delivery prior to 37 weeks…
- Trial name
- PrePPy (NCT01380158)
- Testing
- Cup pessary (Bioteque America, Inc)
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Third Stage of Labor
Homeopathic Remedy for the Third Stage of Delivery
The homeopathic remedy consisting of Arnica and Bellis perennis have been shown in a previous pilot study (n=33) to reduce blood loss during the third stage of delivery, when compared with placebo treatment.
- Trial name
- NCT01156194
- Testing
- Homeopathy 1, Homeopathy 2
- Where
- Israel
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Post-Partum Haemorrhage
A Clinical Trial to Study the Effectiveness of a Care Bundle to Prevent Bleeding After a Woman Has Given Birth
Every six minutes a mother dies from postpartum haemorrhage (PPH) in low-resource countries, in the prime of her life and often leaving behind a young family.
- Trial name
- E-MOTIVE (NCT04341662)
- Testing
- E-MOTIVE intervention, Usual care
- Where
- 6 sites in Kenya, Nigeria and 3 more
- Volunteers
- 99,659 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Postpartum Hemorrhage
Maintenance Infusion of Oxytocin Following Elective Cesarean Deliveries
This study is designed to determine the minimal effective oxytocin maintenance dose required during cesarean delivery to achieve the best effect.
- Trial name
- NCT04946006
- Testing
- Oxytocin
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital