Clinical trials: Delivery of Health Care, active
Liver Diseases, Alcohol Use Disorder
Coronavirus Disease 2019 (Covid-19) Impact on Alcohol-related Liver Disease Patient Outcomes, Care and Alcohol Use
The study consists of a randomized controlled trial evaluating the efficacy and feasibility of a stepped alcohol treatment using telemedicine on unhealthy alcohol use in patients with chronic liver disease receiving care in…
- Trial name
- NCT05191446
- Testing
- Stepped alcohol intervention (SAT) to reduce unhealthy alcohol use, Usual Care (UC)
- Where
- 2 sites in United States
- Volunteers
- 180 people
- Sponsor
- University of California, San Francisco
Cesarean Section
Health Education to Reduce Unnecessary Cesarean Section Among Primigravida Women
This study aims to evaluate the Effectiveness of Health Educational Program for Primigravida Women in Reducing the Rate of Unnecessary Cesarean Section. Specific objectives: 1.
- Trial name
- CS (NCT07810751)
- Testing
- Health Educational Program on Modes of Delivery.
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Neurocognitive Disorders
Efficacy and Safety of Oral Midazolam Used for the Delivery of Care in Elderly Patient With Neurocognitive Disorders and Refusing Care.
The purpose of this study is to assess the effectiveness of oral midazolam on the delivery of care in elderly patients with moderat to severe neurocognitive disorders and opposing care.
- Trial name
- MIRAGE (NCT06638710)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Grenoble
Mental Health, Mental Disorders
A Patient-Partnered, Pan-Canadian, Comparative Effectiveness Evaluation of an Acute Pediatric Mental Health and Addiction Care Bundle
The investigators will determine, in an 8-site, hybrid Type 1 cluster randomized effectiveness implementation trial, if an acute mental health care bundle, compared to standard care, improves wellbeing at 30 days in children and…
- Conditions
- Mental Health, Mental Disorders, Pediatrics, Emergency Psychiatric
- Trial name
- NCT04902391
- Testing
- Health Services
- Where
- 8 sites in Canada
- Volunteers
- 6,800 people
- Sponsor
- University of Calgary
Stress Disorders, Post-Traumatic, Psychological Trauma
Postnatal Debriefing After Adverse Obstetric Events
Adverse or unexpected obstetric events can negatively affect women's psychological well-being and childbirth experience, increasing the risk of postpartum traumatic stress.
- Conditions
- Stress Disorders, Post-Traumatic, Psychological Trauma, Obstetric Labor Complications, Postpartum Period
- Trial name
- DBIRTH (NCT07579273)
- Testing
- Structured Postnatal Debriefing, Usual Care
- Volunteers
- 142 people
- Sponsor
- Parc de Salut Mar
Ischemic Stroke, Transient Ischemic Attack (TIA)
Ambulatory Stroke Unit Treatment for Elderly Patients
ARTIFICE is a prospective, multicenter, randomized, controlled, exploratory non-inferiority trial evaluating whether an ambulatory stroke unit model (aSU) is non-inferior to conventional inpatient stroke unit care (SU) in…
- Conditions
- Ischemic Stroke, Transient Ischemic Attack (TIA), Retinal Ischemia
- Trial name
- ARTIFICE (NCT07420374)
- Testing
- Ambulatory Stroke Unit Care, Conventional Stroke Unit Care
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- University Hospital Heidelberg
Behavioral Assessment of Children, Early Intervention
PaREnting ProgrAm to Enhance PREterm Infants' Health and Development (PREPARE Trial)
Preterm infants are at high risk of developmental delay or disabilities and they do benefit from early intervention programs. Many programs aiming at improving preterm infants' developmental outcome have been proposed with mixed…
- Trial name
- PREPARE (NCT04783220)
- Testing
- Comprehensive structured parent intervention
- Where
- Lebanon
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
LTC-to-hospital Transfer Decision-making
Evaluation of the STEP Intervention for Long-Term Care Residents Facing Hospital Transfer Decisions
This trial will evaluate whether the Supporting Transitions and Empowering Preferences (STEP) toolkit can improve decision-making about hospital transfers in long-term care residents and their substitute decision-makers and…
- Trial name
- STEP (NCT07153341)
- Testing
- STEP Decision Support Toolkit
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- Bruyère Health Research Institute.
Intrathecal Drug Delivery, Refractory Cancer Pain
Intrathecal Therapy Versus Standard Care for Severe Cancer Pain
Approximately 66% of patients with advanced cancer experience pain, which is often inadequately controlled and associated with a decline in health-related quality of life (HRQoL).
- Conditions
- Intrathecal Drug Delivery, Refractory Cancer Pain, Conventional Medical Management
- Trial name
- CAREGIVER (NCT07691840)
- Testing
- Intrathecal Drug Delivery, Comprehensive Medical Management
- Where
- Belgium
- Volunteers
- 72 people
- Sponsor
- Universitair Ziekenhuis Brussel
Pregnancy-Related Anxiety (PrA), Fear of Childbirth
A Midwife-Led Psychoeducational Intervention to Reduce Pregnancy-Related Anxiety in Low-Risk Pregnant Women
The goal of this clinical trial is to evaluate whether an individualized psychoeducational intervention led by an experienced midwife can reduce pregnancy-related anxiety (PrA) in pregnant women during the second and third…
- Trial name
- NCT07323459
- Testing
- A Midwife-Led Psychoeducational Intervention to Reduce Pregnancy-Related Anxiety in Low-Risk Pregnant Women
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Medical University of Gdansk
Atypical Parkinsonism, MSA - Multiple System Atrophy
Integrated Management of Atypical Parkinsonism: A Home-based Patient-Centered Healthcare Delivery Based on Telenursing (IMPACT Study)
This project aims to investigate whether an integrated model based on proactive and reactive telenursing monitoring coordinated by a parkinsonism nurse specialist (case manager) is able to improve care delivery and quality of…
- Conditions
- Atypical Parkinsonism, MSA - Multiple System Atrophy, PSP, Nurse-Patient Relations
- Trial name
- NCT05792332
- Testing
- Telemonitoring, Standard-of-care
- Where
- 4 sites in Italy
- Volunteers
- 164 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Smoking Cessation
Enhancing Smoking Cessation Via Telehealth Options in Primary Care
The purpose of this research study is to evaluate an electronic visit (e-visit) for smoking cessation. Participants will be randomly assigned to receive either the smoking cessation e-visit or not.
- Trial name
- E-STOP (NCT05493254)
- Testing
- Smoking cessation e-visit, Treatment As Usual
- Where
- United States
- Volunteers
- 672 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Infusions, Intravenous, Administration, Intravenous
Digital Transformation of Continuity of Care for Peripherally Inserted Central Catheters: SpadCare Experience
The study focuses on patients who require outpatient infusion of therapy ("Infusions, Intravenous"[Mesh]) "Administration, Intravenous"[Mesh] ("Home Infusion Therapy"[Mesh]) "Parenteral Nutrition, Home"[Mesh] via a peripherally…
- Conditions
- Infusions, Intravenous, Administration, Intravenous, Home Infusion Therapy, Parenteral Nutrition, Home
- Trial name
- SpadCare (NCT06905119)
- Testing
- Digital Transformation of Continuity of Care for Peripherally Inserted Central Catheters
- Where
- Spain
- Volunteers
- 201 people
- Sponsor
- Fundacion Miguel Servet
Heart Failure
ImpleMEntation of a Digital-first Care deLiverY Model for Heart Failure in Uganda
This is a stepped wedge, cluster-randomized study, that will implement a digital-first, multi-component strategy for Heart Failure (HF) to improve HF self-care at 6 Regional Referral Hospital (RRH) outpatient departments in…
- Trial name
- MEDLY Uganda (NCT05955937)
- Testing
- Enhanced HF Clinical Care (Core-HF), Digital health intervention (Medly Uganda) plus enhanced HF clinical care (Core-HF)
- Where
- 7 sites in Uganda
- Volunteers
- 576 people
- Sponsor
- Yale University
Severe Malaria, Severe Anaemia
Post-discharge Malaria Chemoprevention Implementation Trial in Benin
The proposed research aims to conduct implementation trials in Benin, co-designed with national stakeholders, to evaluate different delivery strategies for optimizing health system delivery of post-discharge malaria…
- Trial name
- PDMC-SL (NCT06601712)
- Testing
- Adherence support strategy A, Adherence support strategy B, Control
- Where
- 2 sites in Benin
- Volunteers
- 648 people
- Sponsor
- Institut de Recherche Clinique du Benin
Bone Loss, Hip Prosthesis Infection
Innovative Technologies for Salvage Procedures of Failed Treatments of Osteoarthritis: Biomimetics Solutions (CustomPN)
In this prospective multicenter study, a population of adult individuals consecutively treated for revision hips, requiring a custom-made acetabular implant for non-oncological reasons, will be included.
- Conditions
- Bone Loss, Hip Prosthesis Infection, Arthroplasty Complications
- Trial name
- CustomPN (NCT06527664)
- Testing
- custom-made acetabular implant
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Istituto Ortopedico Rizzoli
Acute Admitted Multimorbid Patients
Poland Integrated Medicines Management (PL-IMM) - Study Assessing the Provision of Complex Clinical Pharmacy Services to Hospitalized Patients
The aim of the study is to assess whether the involvement of a clinical pharmacist in patient care at every stage of hospitalization, from admission to discharge, will improve the quality of healthcare services provided in…
- Trial name
- PL-IMM (NCT07159932)
- Testing
- multidisciplinary treatment
- Where
- Poland
- Volunteers
- 610 people
- Sponsor
- Wroclaw Medical University
Treatment Outcome, Vascular Access
Reduction of Complications Associated With PICC Management
The present study aims to analyze different care routes of the peripheral access central venous catheter to assess which alternative allows a moderate reduction in the level of complications associated with prolonged care…
- Conditions
- Treatment Outcome, Vascular Access, Vascular Access Device, Vascular Access Complication
- Trial name
- PICC managemen (NCT06944327)
- Testing
- MANAGEMENT CARE, traditional care
- Volunteers
- 460 people
- Sponsor
- Fundacion Miguel Servet
Serious Mental Illness, Tobacco Use Disorder
Facilitation to Increase Tobacco Treatment
Smoking disproportionally impacts Veterans, and VA spends $2.7 billion annually on smoking-related health conditions. Veterans with serious mental illness (SMI) smoke tobacco products at triple the rate of Veterans without any…
- Trial name
- FITT (NCT07455526)
- Testing
- Multi-component facilitation
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- VA Office of Research and Development
Insomnia
Sleep Restriction Therapy for Insomnia in Primary Health Care
The recommended treatment for insomnia, cognitive behavioral therapy for insomnia (CBT-I), is effective. However, its long, multi-component nature makes it challenging to implement in ordinary primary care, where most people are…
- Trial name
- NCT04975776
- Testing
- Sleep restriction therapy, Sleep hygiene
- Where
- Sweden
- Volunteers
- 104 people
- Sponsor
- Region Stockholm