Clinical trials: Dementia With Behavioral Disturbance
Dementia, Vascular, Alzheimer Dementia
Accurate WiFi-Based Localization of Dementia Patients For Caregiver Support:
In this Phase II SBIR project we will enhance a wireless WiFi-based insole that was designed and successfully tested during a Phase I trial with elderly persons with dementia and their caregivers, and then investigate its…
- Conditions
- Dementia, Vascular, Alzheimer Dementia, Lewy Body Dementia With Behavioral Disturbance
- Trial name
- NCT03360019
- Testing
- Activlink insole, Activlink Phone Application
- Where
- 2 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Florida
Sleep Disturbance, Dementia
Telephone-Coached Sleep Bibliotherapy for Dementia Caregivers
Sleep disturbances are common among informal caregivers of people with dementia and can negatively affect their physical and psychological well-being.
- Trial name
- NCT07826663
- Testing
- Telephone-Coached Sleep Bibliotherapy, Educational Booklet
- Where
- Hong Kong
- Volunteers
- 120 people
- Sponsor
- The Hong Kong Polytechnic University
Lewy Body Disease, Lewy Body Variant of Alzheimer Disease
Stimulation of Cingulo-opercular Alertness Network
Fluctuations in alertness are very common in persons with Lewy body dementias and are a major source of disability. Changes in a chemical messenger molecule called acetylcholine within certain brain regions may play a role in…
- Conditions
- Lewy Body Disease, Lewy Body Variant of Alzheimer Disease, Lewy Body Dementia With Behavioral Disturbance
- Trial name
- SCAN (NCT04817891)
- Testing
- HD-tDCS
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Michigan
Dementia with Behavioral Disturbance
MEDical CANnabis for Improving Symptoms During Severe DEMentia Disorders in Long-term Care Facility in Geneva
The behavioral and psychological symptoms of dementia affect up to 80% of long-term facilities residents with severe dementia. They seriously alter the quality of life of patients, relatives, and health professionals.
- Trial name
- MedCanDem (NCT05432206)
- Testing
- Cannabis Sativa Oil
- Where
- Switzerland
- Volunteers
- 27 people
- Sponsor
- Fondation pour l'accueil et l'hébérement des personnes âgées
Adapted Garment Prototype, Elderly
Design of a Prototype Garment Adapted to Demented Elderly Subjects With Disturbing Behavioral Problems in the Management of Sphincter Disorders
Alzheimer's disease and related disorders (ADRD) are diseases whose frequency is increasing in elderly subjects. Their evolution is marked by the occurrence, in addition to cognitive disorders, of increasingly disruptive…
- Conditions
- Adapted Garment Prototype, Elderly, Problem Behavior, Dementia
- Trial name
- GERONESIE (NCT05649839)
- Testing
- garment
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Dementia, BPSD
The Role of Aromatherapy With Lavender Oil in the Long-term Care on a Patients Behavioral Problems Associated With Dementia
Testing of Lavender Oil aromatherapy effect on behavior disorders in patients with severe dementia who are hospitalized in the ward for the mentally frail.
- Trial name
- NCT03108781
- Testing
- Lavender Oil, sunflower oil
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Soroka University Medical Center
Alzheimer's Dementia With Behavioral Disturbance
Acupuncture to Reduce Anxiety in Alzheimer's Disease (AD) and AD Related Dementias
The purpose of this study is to investigate the influence of acupuncture on heart rate variability, skin conductance (sweating), and rated behavioral expression of agitation, irritability, and anxiety and mood in qualifying…
- Trial name
- NCT03814382
- Testing
- Acupuncture needle
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Sleep Disturbance, Dementia
Sleep Enhancement for Older Adults Living With Memory Loss And Their Care Partners
The purpose of this study is to determine if a 6-week videoconference intervention to teach skills to improve sleep is practical, acceptable, and helpful to persons living with memory loss, cognitive impairment, and/or dementia…
- Trial name
- SLEEPMATE (NCT06250725)
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Emory University
Alzheimer's Disease
Effects of Light-therapy in Alzheimer's Disease
Background: Management of patients with Alzheimer's disease associated with behavioral disturbances is difficult especially in those with agitation/aggression and insomnia and nighttime behaviors.
- Trial name
- ALZ-Light (NCT02686190)
- Testing
- Luxtherapy
- Where
- France
- Volunteers
- 91 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sleep Fragmentation, Behavioural and Psychiatric Symptoms of Dementia
Therapy Light Rooms for Improved Sleep in Dementia Patients
This intervention study will investigate the effect of therapy light rooms on sleep, circadian rhythms, mood, behavioural problems and function in nursing home (NH) patients with dementia.
- Conditions
- Sleep Fragmentation, Behavioural and Psychiatric Symptoms of Dementia, Dementia
- Trial name
- DEMLIGHT (NCT03357328)
- Testing
- Therapy light room, Standard light
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- University of Bergen
Dementia, Alzheimer Disease
A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Behavioral Disturbances in Patients With Dementia
The purpose of the study is to evaluate the safety and efficacy of risperidone (an antipsychotic medication) versus placebo in the treatment of behavioral disturbances associated with dementia.
- Conditions
- Dementia, Alzheimer Disease, Dementia, Vascular
- Trial name
- NCT00253123
- Testing
- risperidone
- Volunteers
- 626 people
- Sponsor
- Janssen, LP
Autism, Autism Spectrum Disorder (ASD
Cognitive-Behavioral Therapy for Irritability in Adolescents With High Functioning Autism Spectrum Disorder
In addition to the core symptoms, children and adolescents with Autism Spectrum Disorder (ASD) often exhibit disruptive behavior problems including irritability, tantrums, noncompliance, and aggression.
- Conditions
- Autism, Autism Spectrum Disorder (ASD, Asperger's Disorder, Pervasive Developmental Disorder (PDD-NOS)
- Trial name
- NCT01631851
- Testing
- Cognitive-Behavioral Therapy (CBT) for Irritability
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Yale University
Dementia, Pain
Pain in Patients With Dementia and Behavioural Disturbances
In nursing homes (NHs) 80% of the patients have dementia, between 60%-80% exhibit behavioural disturbances (BPSD), and more than 60% have pain. Both pain and BPSD is more common in those with severe dementia.
- Conditions
- Dementia, Pain, Agitation
- Trial name
- NCT01021696
- Testing
- Paracetamol, Morphine, Buprenorphine plaster
- Where
- 18 sites in Norway
- Volunteers
- 352 people
- Sponsor
- University of Bergen
Dementia, Alzheimer Disease
A Study of the Effectiveness and Safety of Risperidone in the Treatment of Behavioral Disturbances in Patients With Dementia
The purpose of the study is to compare the safety and efficacy of risperidone (an antipsychotic medication) to that of placebo in the treatment of behavioral disturbances associated with dementia.
- Conditions
- Dementia, Alzheimer Disease, Dementia, Vascular
- Trial name
- NCT00249145
- Testing
- risperidone
- Volunteers
- 349 people
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
Lewy Body Dementia, Lewy Body Dementia With Behavioral Disturbance
tDCS Effect on Psychotic Symptoms in Dementia With Lewy Bodies (DLB), and Impacts on Caregiver Burden
The goal of this pilot prospective study is to evaluate the effect of tDCS on psychotic-like symptoms in patients with Lewy Body Dementia (LBD).
- Conditions
- Lewy Body Dementia, Lewy Body Dementia With Behavioral Disturbance, Burden, Caregiver, Lewy Body Disease
- Trial name
- MCL-tDCS (NCT06785948)
- Testing
- active-tDCS
- Where
- Monaco
- Volunteers
- 21 people
- Sponsor
- Association de Recherche Bibliographique pour les Neurosciences
Effectiveness, Virtual Reality
Evaluation of the Effectiveness of Virtual Reality Headsets With Hypnotic Scenarios for Hygiene Care in Patients With Alzheimer's Disease or Related Disorders With Behavioral Disturbances
A device combining a virtual reality (VR) headset with hypnotic scenarios may represent an effective tool to reduce anxiety and opposition during hygiene care in patients with neurocognitive disorders presenting with behavioral…
- Conditions
- Effectiveness, Virtual Reality, Hypnotic Scenarios, Hygiene Care
- Trial name
- HYPNOGER 2 (NCT07264439)
- Testing
- VR headset, standard cares
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Autism, Intellectual Disability
Cognitive-Behavioral Therapy for Irritability in Children With Autism Spectrum Disorder and Intellectual Disability
In addition to the core symptoms, children and adolescents with Autism Spectrum Disorder (ASD) often exhibit disruptive behavior problems including irritability, tantrums, noncompliance, and aggression.
- Trial name
- NCT02914951
- Testing
- Cognitive-Behavioral Therapy, Functional magnetic resonance imaging (fMRI)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Yale University
Senile Dementia, Alzheimer Type, Dementia, Alzheimer Type
A Comparison of Two Standard Therapies in the Management of Dementia With Agitation
The purpose of this study is to determine whether an antipsychotic medication alone or an antipsychotic medication in combination with divalproex is the most effective and safest way to treat agitation in elderly patients with…
- Conditions
- Senile Dementia, Alzheimer Type, Dementia, Alzheimer Type, Alzheimer Disease, Dementia
- Trial name
- NCT00208819
- Testing
- risperidone, quetiapine, olanzapine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Emory University
Cognitive Impairment, Dementia With Behavioral Disturbance
The Care for America's Aging Study
Care for America's Aging is a randomized pilot study investigating whether a home health aide training intervention consisting of enhanced dementia-specific curriculum content will improve: 1) behavioral symptoms of older adult…
- Conditions
- Cognitive Impairment, Dementia With Behavioral Disturbance, Dementia, Alzheimer Disease
- Trial name
- CfAA (NCT06021704)
- Testing
- Enhanced home health aide training in dementia and dementia-related behaviors
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Massachusetts General Hospital
Cognitive Function, Sleep
The Effect of Thai Traditional Music on Cognitive Function, Psychological Health and Quality of Sleep Among Thai Older Individuals With Dementia
To determine the effect of Thai traditional music on cognitive function, psychological health and quality of sleep among Thai older individuals with dementia.
- Trial name
- NCT01123993
- Testing
- Music CD
- Where
- 2 sites in Thailand
- Volunteers
- 60 people
- Sponsor
- Phramongkutklao College of Medicine and Hospital