Clinical trials: Demineralization
Dental Caries
Research on the Characteristics and Application of Lactobacillus Rhamnosus X253 as Oral Probiotics
The aim of the study is to study the application of Lactobacillus rhamnosus X253 as oral probiotics by the way of a randomised, double blinded, parallel, placebo-controlled clinical trial, and to eto detect the changes in oral…
- Trial name
- NCT05123651
- Testing
- Lactobacillus rhamnosus X253
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Junlebao Dairy Group Co., Ltd.
Caries, Tooth Decay
Improving Oral Health With Serious Games
This study investigated if computer games can be effective at changing the way children take care of their teeth. We a museum exhibit with 3D virtual reality games called "Attack of the S.
- Conditions
- Caries, Tooth Decay, Cavities, Gingivitis
- Trial name
- AOTSM (NCT02027597)
- Testing
- Attack of the S. Mutans, Follow-up, SnowWorld
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University of Washington
Carious Teeth, Adaptation
Marginal Evaluation of Zirconia Reinforced Lithium Disilicate Partial Coverage Restoration of Egyptian Posterior Teeth.
Objective: To evaluate the marginal adaptation of the zirconia reinforced lithium disilicate (VITA AMBRIA) glass ceramic Inlay/Onlay compared with lithium disilicate(IPS emax Press) glass ceramic Inlay/Onlay in decayed posterior…
- Trial name
- NCT05281861
- Testing
- Zirconia reinforced Lithium disilicate (Vita Ambria) ceramic onlay restoration, Lithium disilicate (IPS e-max press) ceramic onlay restoration
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Attention Deficit Disorder With Hyperactivity, Dental Caries
Oral Status and Prevalence of Dental Trauma in Children Treated With Ritalin Due to Attention-Deficit Hyperactivity Disorder (ADHD)
To evaluate the dental status of children using ritalin and suffering from ADHA in comparison to healthy children.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Dental Caries, Dental Occlusion, Traumatic
- Trial name
- NCT00328224
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Dental Caries
Selective Caries Removal (SCR) Versus Pulpotomy in Preventing Pulp Necrosis and Apical Periodontitis
The study design is a randomized controlled trial and up to 120 teeth, 50 in each of the 2 groups, will be enrolled from the patients at the National University Centre for Oral Health Singapore (NUCOHS) Endodontic unit.
- Trial name
- NCT04672070
- Testing
- Selective Caries Removal, Pulpotomy
- Where
- Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Non-carious Cervical Lesions
Evaluation of the Solvent Evaporation Time of Universal Adhesives in the Quality of Cervical Lesions Restorations
The aim of this study will be to evaluate the effect of prolonging solvent evaporation time on the 6- and 12-months clinical performance of two universal adhesive systems used as selective enamel etch (SEE).
- Trial name
- NCT05945173
- Testing
- Evaporation time for 5 seconds, Evaporation time for 25 seconds, alcohol/water-based universal adhesive
- Where
- Chile
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Dental Caries
Effectiveness of Oral Health Education Programs Among School Children, Their Mothers and Teachers in Fayyum: Cohort Study
Cohort study to evaluate the effect of oral health educational program effect on oral health of school children, their mothers and teachers
- Trial name
- NCT05980273
- Testing
- Educational sessions
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries, Dental
Comparing Hall vs Conventional Technique in Placing Preformed Metal Crowns From Sudan
Preformed metal crowns (PMCs) have high success rates in restoring primary molars in children but they were not generally used by dentists, especially in developing countries due to its demand of high clinical skills with the…
- Trial name
- NCT03640013
- Testing
- Hall Technique PMC
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Khartoum Centre for Research and Medical Training
Caries,Dental
Photobiomodulation on Major Salivary Glands in Children With Caries Activity
The purpose of this trial is to evaluate the efficacy of photobiomodulation of the major salivary glands on salivary parameters in children with caries activity.
- Trial name
- NCT05546528
- Testing
- Photobiomodulation
- Where
- Uruguay
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Early Childhood Caries, Dental Caries
Great Beginnings for Healthy Native Smiles: An Early Childhood Caries Prevention Project
The purpose of this study is to determine whether a bundled best practices oral health intervention utilizing motivational interviewing versus a didactic maternal and child healthy lifestyle intervention will reduce childrens'…
- Trial name
- NCT04556175
- Testing
- Oral Health, Healthy Lifestyle
- Where
- 2 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Carious Lesion
Clinical Evaluation of SDF Combined With KI Versus SDF in Management of Class I Carious Lesions
To evaluate the clinical performance of High-Viscosity Glass Ionomer (EQUIA) versus Silver Diamine Fluoride combined with Potassium Iodide (Riva Star) and Sliver Diamine Fluoride (SDF) under High-Viscosity Glass Ionomer (EQUIA)…
- Trial name
- NCT05485272
- Testing
- Silver Diamine Fluoride combined with Potassium Iodide., Silver Diamine Fluoride., High-Viscosity Glass Ionomer.
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hydration, Dental Caries
Healthy Hydration Pilot in Elementary Schools
This study will pilot a school-based stakeholder-informed hydration intervention and examine its feasibility and preliminary efficacy.
- Conditions
- Hydration, Dental Caries, Body Mass Index
- Trial name
- NCT06132763
- Testing
- Hydration Intervention, Control - Assessments Only
- Where
- United States
- Volunteers
- 563 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Caries, Dental, Risk Reduction
Using a Mouthwash Containing Propolis, Clove Oil and Chlorhexidine to Improve the Caries Risk of High Risk Patients
This study is conducted to determine if using a mouthwash containing propolis, clove oil and chlorhexidine will improve the caries risk of high risk patients in comparison to using a mouthwash containing chlorhexidine only.
- Trial name
- NCT03553628
- Testing
- Chlorhexidine, Propolis and Clove Oil mouthwash, Chlorhexidine mouthwash
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Moataz Gamal Ali Abdul-Maksoud Konsouh
Caries,Dental
CARDEC-PEL: Comparison of Two Methods of Caries Risk Assessment in Children
The aim of the study was to compare dental caries treatment and follow-up based on an elaborate and individualized assessment of caries risk in children, to a simpler risk assessment strategy by means of a double-blind randomized…
- Trial name
- NCT03969628
- Testing
- ICCMS
- Where
- Brazil
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Dental Caries
Evaluation of a New Bioactive Material Versus a Fluoride-Releasing Hybrid Restorative Material in Cervical Lesions
This study will be conducted to evaluate and compare the clinical performance of fluoride, calcium, and phosphate-releasing new bioactive material versus a fluoride-releasing hybrid restorative material in cervical lesions for…
- Trial name
- NCT05149209
- Testing
- cervical restoration
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
HIV, Dental Caries
An Educational Intervention Program to Improve the Oral Health of HIV-Positive Children in Kano, Nigeria.
The aim of this 2- arm randomized-control study is to determine the effect of an oral hygiene self care intervention on the oral health status and oral health-related quality of life (OHRQoL) of HIV-positive children (age: 8-16…
- Conditions
- HIV, Dental Caries, Quality of Life, Oral Disease
- Trial name
- NCT05540171
- Testing
- Oral health education and instructions/training for self-oral care
- Where
- Nigeria
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Aminu Kano Teaching Hospital
Dental Caries
Remineralization Effect of Eggshell Powder on Post-orthodontic White Spot Lesions Compared to CPP-ACP
This research is conducted to compare the remineralization efficacy of eggshell powder gel and CPP-ACP (MI paste) on post-orthodontic white spot lesions.
- Trial name
- REEPP-WSC (NCT03963791)
- Testing
- Eggshell powder gel, CPP-ACP crème
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Toothbrushing, Dental Plaque
BEhavioral EConomics for Oral Health iNnovation Pilot Trial
This Phase I randomized pilot trial will assess the efficacy of a fixed incentive payment program and drawing incentive payment program versus a control program to promote early childhood caries (ECC) preventive health behaviors…
- Conditions
- Toothbrushing, Dental Plaque, Parent-Child Relations, Oral Hygiene
- Trial name
- BEECON Pilot (NCT03862443)
- Testing
- Fixed Incentive, Drawing Incentive
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dental Caries
European Study on Three Different Approaches to Managing Class 2 Cavities in Primary Teeth
The purpose of this randomized clinical trial is to compare the clinical effectiveness of three treatments involving different caries management strategies (conventional restorations, Hall technique, and Non-Restorative Caries…
- Trial name
- NCT01797458
- Testing
- Hall Technique, Non-Restorative Caries Treatment, Conventional Restoration
- Where
- 3 sites in Germany, Lithuania and 1 more
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Caries,Dental
Fluoride Caries-control Effectiveness/Feasibility in Children
The aim of this study is to compare the effectiveness and feasibility of using silver diamine fluoride solution (SDF) vs. sodium fluoride varnish (NaF) for caries management in children from Bogotá (and its suburban areas) and…
- Trial name
- NCT06690008
- Testing
- Experimental group
- Where
- 2 sites in Colombia
- Volunteers
- 814 people, healthy volunteers welcome
- Sponsor
- Universidad El Bosque, Bogotá