Clinical trials: Demodicosis
Meibomian Gland Dysfunction, Cataract
Ultrahigh-resolution Optical Coherence Tomography Imaging of the Anterior Eye Segment Structures
The development of optical coherence tomography (OCT) and its application for in vivo imaging has opened entirely new opportunities in ophthalmology.
- Conditions
- Meibomian Gland Dysfunction, Cataract, Glaucoma, Corneal Transplantation
- Trial name
- NCT03461978
- Testing
- Ultrahigh resolution Spectral Domain OCT
- Where
- Austria
- Volunteers
- 14 people
- Sponsor
- Medical University of Vienna
Demodex Infestation, Rosacea
Facial Demodicosis and Ocular Demodicosis
To understand the association between facial demodicosis and ocular demodicosis, we plan to enroll patients with facial demodicosis, ocular demodicosis, or both, in order to analyze their clinical presentations, the density of…
- Conditions
- Demodex Infestation, Rosacea, Blepharitis, Meibomian Gland Dysfunction
- Trial name
- NCT04377841
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Pandemic, COVID-19, Demodex Infestation
Could Wearing Face Mask Have Affected Demodex Parasite
This study aimed to examine whether wearing masks by healthy individuals during the Covid-19 pandemic created an environment for Demodex mites, by comparing it with the control group.
- Trial name
- NCT06185699
- Testing
- standard superficial skin biopsy (SSSB)
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Nurhan Döner Aktaş
Meibomian Gland Dysfunction, Demodex Infestation of Eyelid
Effect of an Exploratory Vehicle on Meibomian Gland Dysfunction in Patients With Demodex
The purpose of this study is to evaluate and compare the effect of two dosing regimens, BID versus TID dosing, of an Exploratory Vehicle (EV) on meibomian gland dysfunction (MGD) in patients with Demodex lid infestation.
- Conditions
- Meibomian Gland Dysfunction, Demodex Infestation of Eyelid, Blepharitis, Demodectic Blepharitis
- Trial name
- Rhea (NCT06054217)
- Testing
- Vehicle of TP-03
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Tarsus Pharmaceuticals, Inc.
The Focus of the Study is to Assess the Effectiveness of Topical Ivermectin on Eliminating Eyelash Sleeves
Treatment of Ocular Demodex Infestation With Topical Ivermectin Cream 1%
Patients with Demodex infestation of the eyelids will have the sleeves from both eyes cleaned off with microblepharoexfoliation. Afterwards, one eye will be randomly selected for treatment with topical ivermectin 1% cream.
- Trial name
- NCT05213585
- Testing
- Ivermectin 1% cream
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Helm Vision Group
Acne, Demodex Infestation
Demodex Mites in Acne Patients and Herbal Extract Susceptibility
This case-control study aims to detect the presence and density of Demodex mites in patients with acne, identify the species using molecular methods, and evaluate the in vitro survival time of live mites exposed to medicinal…
- Trial name
- NCT07845149
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Meibomian Gland Dysfunction, Blepharitis
Pilot Study Comparing the Safety and Efficacy of Two Dosing Regimens of TP-03 for the Treatment of MGD
The purpose of this study is to compare the safety and efficacy of TP-03, 0.25%, an eyedrop, BID vs TID dosing regimens for the treatment of meibomian gland dysfunction in patients with Demodex lid infestation.
- Conditions
- Meibomian Gland Dysfunction, Blepharitis, Demodex Infestation
- Trial name
- Ersa (NCT05454956)
- Testing
- TP-03, TP-03 Vehicle
- Where
- 5 sites in United States
- Volunteers
- 39 people
- Sponsor
- Tarsus Pharmaceuticals, Inc.
Demodex Infestation, Demodicosis
Evaluation of Treatment Option for Demodicosis in Patients Undergoing Cataract Surgery
Demodex blepharitis is a prevalent cause of comorbid infection among individuals undergoing cataract surgery. Several complications may arise in the postsurgical period from Staphylococcus or Streptococcus co-infections, as…
- Conditions
- Demodex Infestation, Demodicosis, Cataract
- Trial name
- NCT04204954
- Testing
- Ciprofloxacin Ophthalmic Ointment 0.3%, Blephaclean
- Where
- Mexico
- Volunteers
- 160 people
- Sponsor
- Hospital de La Luz
Demodicidosis
Association Between Biologic Therapy and Demodex Density in Psoriasis Patients: A Comparative Study
The goal of this observational study is to investigate whether the density of Demodex mites is higher in psoriasis patients treated with biologic agents compared to treatment-naive or topically treated patients.
- Trial name
- NCT05954572
- Testing
- standardized skin surface biopsy (SSSB)
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Hasan Aksoy
Mite-Borne
Treatment of Ocular Demodicosis by Cleansing the Eyelid Margins Combined With Tea Tree Oil Ointment
To investigate whether the cleaning of eyelid margins increases the effectiveness of traditional tea tree oil eyelid margins in treating mites.
- Trial name
- NCT04451122
- Testing
- cleansing the eyelid margins
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Demodicidosis
Phototherapy: Not a Cause of Demodicosis
The purpose of this study is to determine whether there is an increase in the frequency of demodicosis and the density of Demodex mites after 20 sessions of phototherapy.
- Trial name
- NCT06000189
- Testing
- Standardized skin surface biopsies (SSSB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medeniyet University
Dry Eye Syndromes
Efficiency and Changes of Cytokines Expression in Tear After Intense Pulsed Light Treating Dry Eye Disease
The aim of the current study is to investigate changes of tear cytokines levels as well as the efficacy and the reduction of demodex infestation after OPT IPL treatment in patients with meibomian gland dysfunction-Associated…
- Trial name
- NCT04165785
- Testing
- OPT IPL, MGX
- Where
- China
- Volunteers
- 64 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University