Clinical trials: Dental
Drugs, Investigational
Evaluate Analgesic Efficacy of Fast Release Aspirin
The objective of the study is to evaluate the analgesic efficacy of a single, oral dose of fast release aspirin tablets, 650 mg (2 x 325 mg) compared to regular aspirin tablets, 650 mg (2 x 325 mg) and placebo in subjects with…
- Trial name
- TAROT (NCT01122602)
- Testing
- Acetylsalicyclic acid (Fast acting Aspirin, BAY1019036), Acetylsalicyclic acid (Aspirin, BAYE4465)
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Bayer
Health, Subjective, Gastrointestinal Dysfunction
Personalized Lifestyle Intervention for Improving Functional Health Outcomes Using N-of-1 Tent-Umbrella-Bucket Design
The LIFE-HOUSE research project is designed to evaluate the impact of a personalized lifestyle intervention program on functional capacity as an approach to quantitating health, and its relationship to well understood disease…
- Conditions
- Health, Subjective, Gastrointestinal Dysfunction, Cardiovascular Risk Factor, Autoimmune Diseases
- Trial name
- LIFE-HOUSE (NCT04005456)
- Testing
- Supplements and/or medical foods, Behavioral change support program, Food plan
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Metagenics, Inc.
Dental Caries
Phase 2, Open-Label Study for Safety, Microbiology and PK of Single or Multiple Oral C16G2 Gel Doses
Part A: Open-label, multiple arm, safety, microbiology and pharmacokinetic (PK) study in healthy adult male and female subjects 18-75 years of age. All subjects will be assessed for safety and microbiology parameters.
- Trial name
- NCT02254993
- Testing
- C16G2
- Where
- 2 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Armata Pharmaceuticals, Inc.
Dental Caries
Post-Approval Clinical Study to Evaluate the Calcivis Caries Activity Imaging System
This is a prospective, multi-centre, post-approval clinical study to assess the safety and the performance of the Calcivis Caries Activity Imaging System in aiding the identification of active caries lesions on the occlusal…
- Trial name
- NCT02098304
- Testing
- Calcivis Caries Activity Imaging System
- Where
- 3 sites in United Kingdom
- Volunteers
- 42 people
- Sponsor
- Calcivis Ltd
Pain
Study Evaluating Ibuprofen 600 mg Extended Release (ER) For Dental Pain
The purpose of this study is to assess the efficacy and safety of a single dose of an ibuprofen 600 mg extended release formulation in post-operative dental pain.
- Trial name
- NCT00913627
- Testing
- ibuprofen, naproxen
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- Pfizer
Periodontitis
The Efficacy and Safety of Flurbiprofen Chip Versus Chlorhexidine Chip (Periochip®) in Therapy of Adult Chronic Periodontitis
The purpose of the study is to assess efficacy and safety of Flurbiprofen Chip versus Chlorhexidine chip (Periochip®) in therapy of adult chronic periodontitis.
- Trial name
- NCT01040286
- Testing
- Flurbiprofen, Chlorhexidine
- Where
- Israel
- Sponsor
- Dexcel Pharma Technologies Ltd.
Soft Tissue Anesthesia (Numbness)
Safety and Efficacy Study of NV-101 in Dental Patients
The purpose of this study was: to determine if NV-101 accelerates recovery from numbness compared to placebo to evaluate safety of NV-101
- Trial name
- NCT00154167
- Testing
- NV-101 (phentolamine mesylate solution)
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Novalar Pharmaceuticals, Inc.
Plaque, Dental
Dental Plaque Removal Evaluation and Comparison of Kid's Battery-Operated Toothbrush and Manual Toothbrush
To evaluate and compare the plaque removal efficacy of a children's battery-powered toothbrush and a children's manual toothbrush following a single brushing.
- Trial name
- NCT04794452
- Testing
- Battery operated toothbrush, Manual toothbrush
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Plaque, Dental
Plaque Removal Efficacy of Four Dentifrices Following a Single Brushing
The purpose of this study is to evaluate and compare plaque removal efficacy of four dentifrices following a single timed tooth brushing.
- Trial name
- NCT04794439
- Testing
- Dentifrices
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Doctor Efficiency, Dental Prosthesis Fit
Navigated Photogrammetry Compared to Standard Stereophotogrammetry
The purpose of this study is to compare the clinical outcome of Navigated Photogrammetry to standard stereophotogrammetry techniques in digital dentistry for the following two parameters: The amount of time needed to prepare the…
- Trial name
- FSTMP (NCT06506747)
- Testing
- Navigated Photogrammetry, Standard Photogrammetry
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- X-Nav Technologies, LLC
Gingival Bleeding, Plaque Induced Gingival Disease
Comparative Study of CPC+Zn Mouthwash, Dental Floss, and Essential Oils Mouthwash on Plaque and Gingivitis Reduction
Clinical study evaluating the effectiveness of an alcohol-free mouthwash containing CPC+Zn compared to dental flossing and an essential oils-containing alcohol mouthwash in reducing dental plaque and gingivitis.
- Conditions
- Gingival Bleeding, Plaque Induced Gingival Disease, Gingivitis and Periodontal Diseases
- Trial name
- PGMWI (NCT06607263)
- Testing
- Mouthwash CPC+Zn+F, Essential oils mouthrinse, Dental floss
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Colgate Palmolive
Periodontal Disease
Study of Colonization of Strains L.Plantarum and L.Brevis in the Product AB-DENTALAC Chewing Gum
Study will follow a randomized, double-blind, placebo-controlled design with two groups in parallel,N of 40 patients in 6 weeks of follow up for the evaluation of two different posology models (daily consumption of probiotic gum…
- Trial name
- AB-GUM-2016 (NCT03540498)
- Testing
- AB-DENTALAC [Probiotics (study)]
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
Migraine Disorders
TREXIMA and RELPAX Gastric Scintigraphy Inside and Outside a Migraine
An evaluation of tablet disintegration and absorption and gastric transit of sumatriptan and naproxen sodium from a TREXIMA tablet and eletriptan from a RELPAX 40mg tablet.
- Trial name
- NCT00385008
- Testing
- Combination Product (sumatriptan succinate / naproxen sodium), RELPAX(eletriptan) 40mg Tablet
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- GlaxoSmithKline
Dental Plaque, Oral Hygiene
Efficacy of Manual Toothbrushes in Removing Dental Plaque
This clinical methodology development study will evaluate the plaque removal efficacy of four marketed manual toothbrushes, with differing bristle types and brush head designs, in healthy dentate participants.
- Trial name
- NCT04025684
- Testing
- Oral B Indicator 123, Dr Best Original, Dr Best Multi Expert
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Periodontal Diseases, Periodontitis
Home Use of Dual-light Photodynamic Therapy for Chronic Periodontitis
This early-stage research is designed to determine the efficacy of the Lumoral method in chronic periodontitis patients. Improved supragingival plaque control can help to also sustain the subgingival plaque management in the long…
- Conditions
- Periodontal Diseases, Periodontitis, Plaque, Dental, Plaque Induced Gingivitis
- Trial name
- NCT05425784
- Testing
- Lumoral treatment, Standard oral hygiene self care
- Where
- 3 sites in Finland
- Volunteers
- 41 people
- Sponsor
- Koite Health Oy
Gingivitis, Plaque
ToothWave Calculus Reduction and Accumulation Prevention Study
The objective of the study is to evaluate the safety and efficacy of the home-use device ToothWave (Model H7001) for calculus reduction and the prevention of calculus accumulation.
- Conditions
- Gingivitis, Plaque, Calculus, Dental
- Trial name
- NCT04596761
- Testing
- RF-utilizing powered toothbrush
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Home Skinovations Ltd.
Dental Caries
Efficacy Of A PVP-I Fluoride Varnish
The purpose of the study is to determine the efficacy of Advantage Anti-Caries Varnish. Single-center, double-blind, controlled Phase 2 study with parallel groups of children.
- Trial name
- NCT03082196
- Testing
- Test varnish, Standard varnish
- Where
- Micronesia
- Volunteers
- 284 people
- Sponsor
- Advantage Dental Services, LLC
Extrinsic Dental Stain, Oral Hygiene
Study to Investigate the Stain Control of Two Stannous Fluoride Dentifrices
The purpose of this study is to evaluate and compare the stain build up of two stannous fluoride (SnF2) / sodium tripolyphosphate (STP) dentifrices of differing abrasivity levels, with a marketed standard fluoride dentifrice and…
- Trial name
- NCT03160703
- Testing
- Stannous fluoride (SnF2, 0.454%), Sodium tripolyphosphate (STP, 5%), 2.0% abrasive silica, Stannous fluoride (SnF2, 0.454%), Sodium tripolyphosphate (STP, 5%), abrasive silica (3.5%), Sodium Monofluorophosphate (1000 ppm fluoride ), RDA~80
- Where
- Canada
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentinal Hypersensitivity, Dental Pain
The Effects of Potassium Nitrate in Reducing Dentinal Hypersensitivity
A randomized, controlled, double blind exploratory study to explore the effects of two different potassium nitrate concentrations and water on exposed dentine in reducing dentinal hypersensitivity.
- Trial name
- NCT01587950
- Testing
- Potassium Nitrate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- GlaxoSmithKline
Teeth Loss
Controlled Pilot Study to Assess Soft Tissue Reaction at the Crestal Part of a Dental Implant With ESTA Surface
This study will investigate the effect on the soft tissue that is in contact with a dental implant with a modified surface of the neck (the part of the implant that is above the bone and in contact with the soft gum tissue).
- Trial name
- NCT02159183
- Testing
- Standard Plus ESTA STL Roxolid implant, Standard Plus STL implant
- Where
- 4 sites in Switzerland
- Volunteers
- 43 people
- Sponsor
- Institut Straumann AG