Clinical trials: Dental Alveolus
Tooth Loss, Tooth Diseases
The Cortical Shield for Facial Bone Reconstruction
To evaluate a novel technique of bone regeneration and simultaneous implant placement in severely damaged sockets.
- Conditions
- Tooth Loss, Tooth Diseases, Tooth Fracture, Tooth Injuries
- Trial name
- NCT04827693
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Verdugo, Fernando, DDS
Dental Alveolus, Oral Surgical Procedures, Preprosthetic
A Prospective Study: Alveolar Ridge Augmentation Using Tenting Screws, Acellular Dermal Matrix and Combination Particulate Grafts
When a tooth or teeth are extracted, a defect in the bony ridge often forms. This loss of bone may make it impossible to place a dental implant.
- Trial name
- NCT01572298
- Testing
- allograft alone, allograft with autograft
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Dental Implants, Single-Tooth
Differences Between Two Type Implants in Post-extraction Alveolus
One of the challenges of current implantology involves the preservation or reduction of existing bone resorption, mainly in the buccal bone plate, after tooth loss, which becomes of special importance in the anterior region of…
- Trial name
- NCT05665231
- Testing
- A - Bone defect (clinical variables), B- Bacterial plaque index (O'Leary index)(clinical variables), C- Probing depth
- Where
- Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Bilateral Complete Cleft Lip and/or Alveolus
Tympanometric Analysis in Cleft Palate
Purpose: Characterize the profile of tympanometric patients with cleft lip and palate in the post surgery period and correlate it with the time of palatoplasty.
- Trial name
- NCT01820689
- Testing
- Tympanometry measurement
- Volunteers
- 16 people
- Sponsor
- Centro de Diagnostico Auditivo de Cuiaba
Cleft Palate, Cleft Palate, Unilateral, Complete
MRI Assessment of Velopharyngeal Anatomy After Modified Furlow-Buccinator Flap in Late Primary Palate Repair
The goal of this case series study is to learn if magnetic resonance imaging (MRI) can show how well the palate and throat muscles work at rest and during speech after late cleft palate repair.
- Conditions
- Cleft Palate, Cleft Palate, Unilateral, Complete, Cleft Lip, Cleft Alveolus and Cleft Palate, Cleft Palate Repair
- Trial name
- NCT07514091
- Testing
- Modified Furlow Palatoplasty combined with buccinator myomucosal flap
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Cairo University
Cleft Lip and Cleft Palate, Cleft Lip, Cleft Alveolus and Cleft Palate
Effect of Collagen Matrix Graft on Palatal Fistula Formation After Cleft Palate Repair
Palatal fistulas are a major burden to surgeons and patients in the management of cleft palate. Their high rate of occurrence and recurrence makes them particularly challenging even to the highly skilled surgeon.
- Conditions
- Cleft Lip and Cleft Palate, Cleft Lip, Cleft Alveolus and Cleft Palate, Cleft Palate
- Trial name
- NCT05454670
- Testing
- Two-flap palatoplasty
- Where
- Nigeria
- Volunteers
- 48 people
- Sponsor
- Lagos State University
Nasoalveolar Fistula (Defect)
Clinical Assessment of Usage of Cleft Margin Flap With Anterior Palatal Closure in Closure of Naso-alveolar Defect.
During primary cleft lip repair in patients who were born with cleft lip and palate, usage of cleft margin flap with anterior palatal closure will be done in an attempt to close the Naso-alveolar fistula (defect) that usually…
- Trial name
- NCT03922438
- Testing
- usage of cleft margin flap with anterior palatal closure during primary cleft lip repair.
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Loss
mp3 vs Apatos in Post-extractive Sockets
The primary aim of the present multicenter randomized controlled trial was to evaluate and compare the shortterm clinical and histological changes of extraction sockets after ridge preservation procedures with changes of…
- Trial name
- NCT02644070
- Testing
- alveolar bone preservation with mp3, alveolar bone preservation with apatos, stabilization with membrane
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tuscan Dental Institute
Bilateral Complete Cleft Lip And/or Alveolus and Acrylic Splint, and, Maxillary Deficiency
Evaluating the Impact of Prefabricated Acrylic Splints on Premaxillary Stability in Alveolar Cleft Bone Graft Repairs: a Randomized Controlled Trial
Rationale for conducting the research: Bilateral alveolar clefts pose significant management challenges, with current treatments like autogenous bone grafting showing instability in up to 40% of cases within a year, risking graft…
- Conditions
- Bilateral Complete Cleft Lip And/or Alveolus and Acrylic Splint, and, Maxillary Deficiency, Stability
- Trial name
- RCT (NCT06807645)
- Testing
- Clinical Trial Intervention Description General Study Setup Objective: To compare the efficacy of using a custom-made prefabricated acrylic splint versus no splint in maintaining premaxillary stabilit
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cleft Lip and Palate
Progression of Grafted Bone Density in Cleft Alveolus
The patients with unilateral and bilateral cleft lip and palate received alveolar bone graft surgery. Two time points of cone beam CT were taken for all the patients: post-operative 6 months, and post-operative 2 years.
- Trial name
- CDAABG (NCT04987190)
- Testing
- alveolar bone graft
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Cleft Lip Palate
Quadratus Lumborum Block for Iliac Bone Harvest in Pediatric Cleft Alveolus Repair
This prospective, randomized, double-blinded controlled trial will investigate the effectiveness of a lateral quadratus lumborum (QL) block in 50 children aged 6-14 years undergoing iliac crest bone grafting for cleft alveolus…
- Trial name
- NCT07846761
- Testing
- Lateral quadratus lumborum block
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Intravenous Anesthesia
Opioid Based Anaesthesia vs Opioid Free Anesthesia in Cleft Lip, Palate ,Alveolus Surgery.
Peri-operative opioid administration has long been one of the three pillars of 'balanced anaesthesia',over the span of just a few years,opioids were widely used in perioperative analgesia because of pain as the fifth vital…
- Trial name
- NCT04081909
- Testing
- Fentanyl，Remifentanil, Ketamine,Dexmedetomidine
- Volunteers
- 60 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Bone Resorption
State of the Art Immediate Implant Placement in the Premaxilla
The goal of this clinical study is to learn how well immediate implant placement works in the front upper jaw (premaxilla) when using flapless guided surgery, hard and soft tissue augmentation, and immediate provisional crowns.
- Trial name
- NCT07080710
- Testing
- Immediate implant placement
- Where
- 2 sites in Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Ghent
L-PRF, Dental Implants
Evaluation of the Effect of Leucocyte Platelet-Rich Fibrin (L-PRF) Technique Applied in Post-extraction Sockets Before Placement of Dental Implants
Aim of study: The application of L-PRF membrane in post-extraction sockets outmatches the use of a) allograft covered with a collagen fleece b) allograft combined with L-PRF membrane c) natural healing, with reference to bone…
- Conditions
- L-PRF, Dental Implants, Osseointegration, Alveolar Bone Grafting
- Trial name
- NCT07387913
- Testing
- Allograft and collagen membrane, Allograft and L-PRF membrane, L-PRF
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Tooth Extraction Status Nos
Single Tooth Extraction in Damaged Alveoli and Implant Site Development:TootToo
It is unclear what is the best approach to implant site development after tooth extraction when the pathology leading to extraction has damaged the alveolus.
- Trial name
- NCT05235048
- Testing
- Tooth extraction, Tooth extraction and socket seal with connective tissue graft, Tooth extraction and socket seal with BRG and connective tissue graft and
- Volunteers
- 160 people
- Sponsor
- The European Research Group on Periodontology (ERGOPerio)
Periodontitis, Dental Caries
Comparison of Topical Analgesic With Saline Rinses in Post Extraction Healing
The aim of this study is to determine the beneficial effect of mouth rinses, both topical analgesic and saline regimens as an adjuvant therapy in the presence of standard prescription of post-operative pain killers on the…
- Conditions
- Periodontitis, Dental Caries, Hypertension
- Trial name
- NCT02921165
- Testing
- analgesic mouth rinses (dissolved Aspirin), Normal saline rinses.
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Dental Implant
Immediate Implants: to Graft or Not to Graft, That is the Question.
The aim was to compare two protocols for immediate implants with fixed provisional restoration, no grafting (trimodal approach=TA) versus grafting both osseous gap and peri-implant mucosa (trimodal approach with modification of…
- Trial name
- TAOM-TA (NCT05927181)
- Testing
- TAOM
- Where
- Spain
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Tooth Extraction
Combination Therapy Effect of Laser on Wound Healing and Bone Regeneration of Dental Sockets
The goal of this clinical trial is to learn if the laser works to improve wound healing and bone regeneration after tooth extraction.
- Trial name
- NCT06552936
- Testing
- Diode Laser 980 nm.
- Where
- 2 sites in Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Sharif Medical Research Center
Immediate Dental Implant Placement, Connective Tissue Graft
Hard and Soft Tissue Changes Following Immediate Implant Placement With Buccal Gap Management: Comparing the Use of Deproteinized Bovine Bone Mineral Socket Grafting and Sub-epithelial Connective Tissue Graft in a 6-month Pilot Study.
This study aims to assess hard and soft tissue changes after immediate implant placement, comparing the use of a deproteinized bovine bone mineral and sub-epithelial connective tissue graft in the management of the buccal gap.
- Conditions
- Immediate Dental Implant Placement, Connective Tissue Graft, Bone Substitutes
- Trial name
- NCT07518823
- Testing
- immediate implant placement + SG, Groupe 2 : CTG
- Where
- Lebanon
- Volunteers
- 8 people
- Sponsor
- Saint-Joseph University
Chronic Periodontitis Apical, Embedded Tooth
Post-extractive Alveolus Regeneration
Healing of post-extraction alveolus is a complex process that involves soft and hard tissues regeneration. Pain, swelling, difficulty of opening the mouth, delayed healing of bone tissue, alveolitis and horizontal or vertical…
- Trial name
- NCT04763187
- Testing
- Tooth extraction
- Where
- Lithuania
- Volunteers
- 43 people
- Sponsor
- Lithuanian University of Health Sciences