Clinical trials: Dental Anaesthesia
Low Cardiac Output Syndrome
Patients With Low Cardiac Output Syndrome Undergoing Local Dental Anesthesia
Patients with low cardiac output syndrome requiring surgical and periodontal dental treatment will be selected to undergo the dental procedure using local dental anesthetic: 2% lidocaine with epinephrine and 2% lidocaine without…
- Trial name
- NCT06355882
- Testing
- Anesthetic infiltration
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Sao Paulo General Hospital
Dental Anxiety
Children's Drawing as a Projective Tool to Assess Dental Anxiety
The aim in this study is to compare the results of anxiety measurement of the child using the CD:H scale with the long-used Face,Legs,Activity,Cry and Consolability scale (FLACC scale) , Frankl behaviour rating scale and pulse…
- Trial name
- NCT06369038
- Testing
- observation of level of dental anxiety in children
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Cairo University
Drug Effect, Tooth Extraction
Comparison of the Efficacy and Safety of Two Homologous Active Principles for Local Dental Anesthesia
In the complexity of the Dental care the third molar surgery is one of the most common procedures, it is indicated for multiple reasons like infections in root canal, prosthetics or even esthetical purposes.
- Trial name
- ECA (NCT04166890)
- Testing
- Articaine / EPINEPHrine Cartridge
- Where
- Colombia
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Dental Caries in Children, Dental Diseases
Gurney Journey: Virtual Reality Distraction
The aim of this study is to determine whether a software virtual reality (VR) program provided during transportation to anesthesia induction reduces anxiety before the procedure, and compliance in pediatric patients.
- Conditions
- Dental Caries in Children, Dental Diseases, Gastrointestinal Surgery, Procedures Requiring Anesthesia
- Trial name
- NCT06283108
- Testing
- Standard Child Life Preparation and Support + Meta Quest 2 VR headset with Gurney Journey (a mixed reality experience), Standard Child Life Preparation and Support
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Colorado
Pain Perception
Pain Perception Following Computer-Controlled vs. Conventional Dental Anesthesia
This single-blind two-arm randomized control trial (RCT) aims to evaluate the pain perception during and following administration of dental local anaesthesia using two different systems; i.e.
- Trial name
- NCT05192902
- Testing
- Computer-controlled Local Anaesthesia (CCLA), Conventional Local Anaesthesia
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Giessen
Endodontic Inflammation
Comparison of Osteocentral Versus Locoregional Anesthesia in Case of Mandibular Molar Pulpitis
The irreversible acute pulpitis is the most common emergency at the hospital during dental consultation. Pulpitis are characterized by intense and spontaneous oro-facial pains.
- Trial name
- COQ (NCT03802305)
- Testing
- computerized intraosseous technique (Quicksleeper™), loco-regional anesthesia (IANB technique)
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Nantes University Hospital
Anesthesia
Comparison of Intranasal Kovacaine Mist, and Placebo for Anesthetizing Maxillary Teeth in Adults
The purpose of this study is to compare the efficacy of Kovacaine Mist, and Placebo for inducing pulpal anesthesia of the maxillary teeth in adults.
- Trial name
- NCT01745380
- Testing
- Tetracaine HCl 3% and Oxymetazoline HCl 0.05%
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- St. Renatus, LLC
Rheumatic Heart Disease, Pregnancy
Dental Anesthesia in Pregnant Women With Rheumatic Heart Disease
The hemodynamic parameters of 31 pregnant women with rheumatic valve disease, undergoing restorative dentistry under local anesthesia with 2% solution of lidocaine, divided in two groups, with (Group LE) and without 1:100,000…
- Conditions
- Rheumatic Heart Disease, Pregnancy, Dental Caries
- Trial name
- NCT00482573
- Testing
- Dental local anesthesia
- Where
- Brazil
- Volunteers
- 31 people
- Sponsor
- University of Sao Paulo
Anesthesia, Local
Clinical Outcomes Mandible: Buffered 1% vs. Non-Buffered 1% Lidocaine
Assess the clinical impact of Buffered 1% lidocaine with epinephrine as compared to the Non-buffered 1% lidocaine with epinephrine in dental and oral surgical procedures.
- Trial name
- NCT03127943
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
This Study Aims to Evaluate the Effectiveness of the INJEX Device in Administering Local Anesthesia
Effectiveness of Needle-Free Infiltration Anesthesia in Reduction of Dental Pain and Anxiety During Local Anesthesia.
Local anesthesia is a common and essential procedure for the majority of dental treatments. The most frequently used method of administration is needle injection.
- Trial name
- NCT07426523
- Testing
- INJEX 30, Traditional syringe
- Where
- Syria
- Volunteers
- 52 people
- Sponsor
- Damascus University
Impacted Third Molar Tooth
Perineural and Systemic Dexamethasone Use in Dental Surgeries in Terms of Anesthesia Duration and Postop Complaints
Participants will be asked to use some medications after the tooth extraction procedure. These drugs can be used in different ways.
- Trial name
- NCT06318013
- Testing
- vitality test
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Anxiety, Dental, Behavior
The Effect of Using Camouflaged Dental Syringe
Seeing the dental syringe can be terrifying, especially for young children. Hiding the dental syringe during local anesthesia (LA) administration can sometimes be challenging for the pediatric dentist.
- Trial name
- Camouflage (NCT06116994)
- Testing
- The buccal infiltration anesthesia with a camouflaged dental syringe (Angelus ™), The buccal infiltration anesthesia with a conventional dental syringe
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Discomfort
Comparing Pain Levels With or Without Topical Anesthesia During Infiltration Injection in Patients Undergoing Tooth Extraction.
This randomized clinical trial aims to assess whether the application of 5% topical lidocaine before infiltration anesthesia reduces pain in patients undergoing tooth extraction.
- Trial name
- NCT07707557
- Testing
- 2% Lidocaine hydrochloride infiltrate injection, 5% topical Lidocaine hydrochloride preparation
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Abbasi Shaheed Hospital
Physiological Effects of Drugs, Anesthetics
Effectiveness of the Comfort-In Needle Free Injection System During Palatal Infiltrative Anesthesia
The goal of this randomized clinical trial is to compare two different injection methods in children. The main question it aims to answer is: Is the needle-free injection method more painless than the traditional dental method?…
- Trial name
- NCT06606587
- Testing
- Comfort-in Jet Injection Method, Traditional Dental Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Dental Anxiety
Effectiveness Of Magic Tricks Distraction Technique
Dental anxiety among children is a significant challenge in pediatric dentistry, often hindering effective dental care. This clinical study aims to evaluate the effectiveness of two magic tricks distraction techniques (magic rope…
- Trial name
- NCT07075458
- Testing
- Magic Rope Trick, Magic Thumb Sleeves, Tell-Show-Do (TSD)
- Where
- Egypt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Anxiety, Pain
Different Local Anesthesia Techniques for Mandibular Primary Molar Pulpectomy
This study aims to compare the effects of computer-controlled local anesthesia and conventional inferior alveolar nerve block on dental anxiety and pain in children undergoing pulpectomy of mandibular primary molars.
- Conditions
- Dental Anxiety, Pain, Pulpal Diseases
- Trial name
- NCT07714915
- Testing
- Computer-Controlled Local Anesthesia, Conventional Inferior Alveolar Nerve Block, Articaine hydrochloride with epinephrine 1:100,000
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Anesthesia
VR Sedation in Third Molar Surgery
Anaesthesia or sedation for dental surgery is Challenging. Over-sedation, leading to upper airway obstruction, desaturation and apnoea, is very common.
- Trial name
- NCT04540666
- Testing
- Propofol
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Surgical Complications From Local Anesthesia, Dental Implant Failed
Compare Subperiosteal and Loco-Regional Anesthesia in Posterior Mandible Dental Implant Installation
In patients that are going to receive a dental implant in the posterior mandible (distal from canine), does the subperiosteal anesthetic technique with Articaine 1:100.000 4 % Epinephrine compared to the loco-regional one…
- Conditions
- Surgical Complications From Local Anesthesia, Dental Implant Failed, Anesthesia Complications, Anesthesia Morbidity
- Trial name
- NCT01963754
- Testing
- Dental Implants in Posterior Mandible, Subperiosteal 1:100.000 Articaine 4% epinephrine, Loco-regional 1:100.000 Articaine 4% epinephrine
- Where
- Portugal
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Therapy Animals, Dental Anxiety
Do Therapy Dogs Improve Behavior and Reduce Anxiety in Pediatric Dental Patients?
The goal of this clinical trial is to assess whether the presence of a certified therapy dog during dental procedures that require an injection reduces anxiety and improves behavior in pediatric dental patients.
- Conditions
- Therapy Animals, Dental Anxiety, Child Behavior, Anesthesia, Local
- Trial name
- NCT06057090
- Testing
- Therapy Dog
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Dental Anxiety, Dental Fear
Comparing Augmented Reality and Virtual Reality Glasses to Help Children Feel Less Pain and Anxiety During Local Anesthesia
The goal of this clinical trial is to learn if audio-visual method of distraction is useful to control the pain and fear associated with dental treatment in children.
- Conditions
- Dental Anxiety, Dental Fear, Dental Fear and Anxiety
- Trial name
- NCT07060170
- Testing
- Augmented Reality Glasses, Virtual Reality Glasses
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riham Abbas