Clinical trials: Dental Anaesthesia
Molar Incisor Hypomineralization, Anesthesia, Local
Effect of Silver Diamine Fluoride on Local Anesthesia in Hypomineralized Molars
The purpose of this randomized, controlled clinical study is to evaluate if application of 38% SDF increases the efficacy of local anesthesia during operative dentistry on permanent molars affected by molar-incisor hypoplasia…
- Trial name
- NCT05964387
- Testing
- SDF
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Anesthesia, Dental, Pain, Postoperative
Articaine vs Lidocaine for Pediatric Dental Procedures
The purpose of this study is to compare the efficacy of two types of local anesthesia (articaine and lidocaine) for infiltration anesthesia during restorative dental procedures on lower teeth in pediatric patients.
- Trial name
- NCT03318952
- Testing
- lidocaine, articaine
- Where
- United States
- Sponsor
- Boston University
Pediatric Dental General Anesthesia, Restoration
Clinical Performance and Failure Rates of Restorations Following Pediatric Dental Rehabilitation Under General Anesthesia
Full-mouth dental rehabilitation under general anesthesia (GA) is frequently required for young children with extensive dental caries, behavioral challenges, or special healthcare needs.
- Conditions
- Pediatric Dental General Anesthesia, Restoration, Clinical Performance, Full Mouth Rehabilitation
- Trial name
- NCT07827833
- Testing
- Routine Restorative Materials and Treatment Methods
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Tanta University
Soft Tissue Anesthesia (Numbness)
Safety and Efficacy Study of NV-101 in Dental Patients
The purpose of this study was: to determine if NV-101 accelerates recovery from numbness compared to placebo to evaluate safety of NV-101
- Trial name
- NCT00154167
- Testing
- NV-101 (phentolamine mesylate solution)
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Novalar Pharmaceuticals, Inc.
Dental Anesthesia
MRI and Local Anesthesia
The purpose of this research is to investigate the utility of using dental-dedicated MRI as a measurement tool to observe and evaluate the administration of local anesthesia in dental patients.
- Trial name
- MRI and LA (NCT07602686)
- Testing
- ddMRI
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Minnesota
Dental Pain, Dental Anxiety and Child Behavior Are Assess in Response to Dental Injection
Effect of Computer-controlled vs. Conventional Injection on Pain and Anxiety in Children
This randomized controlled trial aims to compare the effectiveness of Computer-Controlled automatic injection device versus conventional injection techniques in pediatric dental patients.
- Trial name
- NCT07193342
- Testing
- computer controlled automatic injection (Star pen® system), conventional anesthetic syringe
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Future University in Egypt
Postoperative Complications
The Effect of Local Anaesthesia Technique on the Recovery After Dental Treatment in General Anaesthesia
Use of local anaesthesia during full mouth dental rehabilitation under general anaesthesia is an everyday practice. It enables better control of the post-extraction bleeding and better control of physiological responses.
- Trial name
- NCT04156334
- Testing
- Extraction of teeth in general anaesthesia using either computer-controlled intraosseous anesthesia device or carpule for local anaesthesia
- Where
- Slovenia
- Volunteers
- 120 people
- Sponsor
- University of Ljubljana
Postoperative Delirium, Postoperative Pain
Effect of Electroencephalography Guided General Anesthesia on Postoperative Delirium in Children
Participants aged 4-10 years (92 patients), who came to the Hospital Operating Room at the University Faculty of Dentistry with an indication for dental treatment under general anesthesia due to lack of cooperation, will be…
- Trial name
- NCT06400706
- Testing
- EEG guided general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Pain
Comparison Between the Dentapen and Vibraject
A split-mouth, controlled trial aimed to assess patient-reported pain levels during local anaesthesia administration to the buccal side of the maxillary posterior teeth using Vibraject-assisted injection and the Dentapen® system…
- Trial name
- NCT06790433
- Testing
- Vibraject, Dentapen
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Intubation; Difficult or Failed, Postoperative Pain
The Comparison of Direct Macintosh Laryngoscopy and HugeMed Video Laryngoscope for Nasotracheal Intubation in Children
Forty-four patients aged 4-10 years who applied to Aydın Adnan Menderes University Faculty of Dentistry for dental treatment under general anesthesia will be selected and divided into 2 groups by simple randomization.
- Trial name
- NCT05121597
- Testing
- HugeMed Videolaryngoscope
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Anesthesia, Local, Child Behavior
The Effect of Needle-free Injection System on Dental Injection Pain in Children
The aim of this study was to compare paediatric patients' pain perception and behavioural response during dental injection using needle free injection (NF) or traditional injection method (TM) over two consecutive visits.
- Conditions
- Anesthesia, Local, Child Behavior, Pain
- Trial name
- NCT06541925
- Testing
- Injection with the needle-free (NF) system, Injection with the traditional method (TM)
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Marmara University
Injection Pain, Local Anesthesia Infiltration
Sweet-Tasting Solution Versus Placebo to Reduce Pain During Local Anesthetic Injection in Children
The goal of this clinical trial is to learn whether applying a sugar-free flavored sweet solution (SFSS) before local anesthesia helps reduce injection pain in children.
- Conditions
- Injection Pain, Local Anesthesia Infiltration, Pain, Injection Pain Prevention
- Trial name
- NCT07279285
- Testing
- Sugar-free-flavored sweet tasting solution
- Where
- Jordan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Molar Incisor Hypomineralisation
Local Anesthesia With Lidocaine or Articaine for Molars Affected by MIH
Aims: Comparison of injection pain with lidocaine and articaine in children with MIH . Comparison of the efficacy of lidocaine and articaine during treatment of MIH molars.
- Trial name
- NCT05200884
- Testing
- Lidocaine 2%, Articaine 4%
- Where
- Syria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Latakia University
Complication of Anesthesia
Postoperative Complication After G.A
What are the possible postoperative complications that may occur for children following dental treatment under general anaesthesia and is there a correlation between those complications and type of dental treatment done?
- Trial name
- NCT05758974
- Testing
- dental treatment
- Volunteers
- 110 people
- Sponsor
- Cairo University
Anesthesia, Dental
Study of NV-101 for Efficacy, Pharmacodynamics, and Safety in Dental Patients Undergoing Maxillary Procedures
This Phase 3 clinical study is designed as a multicenter, randomized, blinded, controlled study to evaluate the efficacy, pharmacodynamics, and safety of NV-101 administered as a submucosal injection following completion of a…
- Trial name
- NCT00309335
- Testing
- Phentolamine Mesylate (NV-101)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Novalar Pharmaceuticals, Inc.
Dental Anxiety, Pain Management
Impact of Local Anesthesia Techniques on Children's Dental Treatment Experience
compare the effectiveness of several local anesthetic delivery systems in managing pain, anxiety, behavior, and vital signs among pediatric dental patients.
- Conditions
- Dental Anxiety, Pain Management, Pediatric Dentistry
- Trial name
- NCT07106138
- Testing
- Conventional syringe injection, Star Pen, Comfort-In
- Where
- Syria
- Volunteers
- 112 people
- Sponsor
- Latakia University
Underdosing of Local Anesthetics, Initial Encounter
Formulations of Liposomal Local Anesthetics
This blinded cross-over study aim to evaluate the efficacy of liposome-encapsulated ropivacaine formulation for dental anesthesia.
- Trial name
- NCT01307969
- Testing
- Ropivacaine
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Dental Anxiety
Modification of Blood Pressure Levels and Oxygen Saturation in Patients Undergoing Conscious Sedation
The objective is to compare the changes produced in cardiological and respiratory parameters in three groups of patients undergoing oral surgery.
- Trial name
- NCT03789942
- Testing
- Oral surgery
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Clinica Luis Ortiz
Molar Incisor Hypomineralization
Digital Intraosseous Anesthesia in MIH-Affected Permanent Molars
This multicentre, randomized clinical trial compared digital intraosseous anaesthesia with conventional local anaesthetic techniques in children aged 6-12 years receiving restorative treatment for MIH-affected permanent first…
- Trial name
- DIA-MIH (NCT07736677)
- Testing
- SleeperOne 5 Computer-Controlled Intraosseous Anaesthesia System, Conventional Maxillary Infiltration Anaesthesia, Conventional Inferior Alveolar Nerve Block Anaesthesia
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Ege University
Wisdom Tooth, Dental Impaction
Efficacy and Safety of Articaine and Lidocaine in Extraction of Wisdom Teeth of Upper and Lower Jaws
Local anesthesia drugs and anesthesia technique play an imperative role in dental treatment. The purpose of this study was to compare the efficacy and safety of different dental local anesthetics drugs and brands in clinical use…
- Trial name
- NCT05804630
- Testing
- Different dental anesthetic agents during wisdom tooth surgery (Orabloc®, Octocaine®, and Xylestesin-A®)
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital