Clinical trials: Dental Caries, pill or tablet or capsule or oral, open to volunteers
- Condition Dental Caries
- Drug or intervention pill OR tablet OR capsule OR oral
- Status Open to volunteers
Carious Lesion, Ready-made Crowns
The Relation Between Oral Hygiene and Microbial Load in the Oral Cavity After Restoring Primary Molars With Two Types of Ready-made Crowns
Following the restoration of primary molars with stainless steel and bioflex crowns, an evaluation of the current state of oral hygiene in relation to the amount of microorganisms and gingival health in the oral cavity will be…
- Trial name
- bioflex crown (NCT06767670)
- Testing
- stainless steel crown, bioflex crown
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Caries,Dental
Ozone Application Before Fissure Sealants
Decay is a multifactorial infective degenerative disease of hard dental tissues, caused by Streptococcus mutans and Lactobacillus forming the bacterial biofilm of teeth surfaces.
- Trial name
- NCT04040920
- Testing
- Ozone, Pits and fissure sealants
- Where
- Italy
- Volunteers
- 67 people
- Sponsor
- IRCCS Burlo Garofolo
Incipient Interproximal Caries
Can SAP P11-4 Affect The Appearance of Interproximal Cavities on an X-ray in a Military Population
The primary objective of the protocol is to learn about how SAP P 11-4 (produced commercially as Curodont products) can be used in a military population to treat incipient dental caries, or developing cavities that are still…
- Trial name
- NCT07829328
- Testing
- 0.05% Sodium Fluoride with Self-Assembling Peptides
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Tripler Army Medical Center
Dental Caries, White Spot Lesions
QLF and Digital Imaging for Caries Activity Assessment After Orthodontic Treatment
This prospective longitudinal observational study aims to evaluate the diagnostic performance and agreement of Smartphone photography, intraoral 3D imaging, Quantitative Light-Induced Fluorescence Digital (QLF-D), and ICDAS…
- Conditions
- Dental Caries, White Spot Lesions, Caries Lesion Activity, Post-Orthodontic Enamel Demineralization
- Trial name
- NCT07608471
- Volunteers
- 30 people
- Sponsor
- Universidad El Bosque, Bogotá
Dental Caries (Diagnosis), Dental Plaque (Diagnosis)
Intra Oral Scan and CBCT Aided Diagnosis of Dental Plaque and Caries
In this prospective controlled trial, patients will be enrolled at the University Hospital Ghent. Inclusion criteria are: age between 18 and 70 years old, presence of 20 or more teeth, and have a minimum one carious tooth…
- Trial name
- NCT06945354
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University Ghent
Dental Caries, Dental Caries in Children
Technology-enabled Anticipatory Guidance and Peer Support in Empowering Parents to Prevent Early Childhood Caries
Early Childhood Caries (ECC) is a significant clinical and public health challenge that the world and the Singapore population are facing.
- Conditions
- Dental Caries, Dental Caries in Children, Diet Habit
- Trial name
- NCT06558955
- Testing
- Technology-enabled anticipatory guidance and peer support, Conventional health education
- Where
- Singapore
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Dental Caries, Insufficient Dental Filling
A Clinical Trial to Compare the Safety and Performance of Two Different Curing Modes in the Direct Filling Therapy in Deciduous Teeth
The overall aim of this clinical investigation is to assess the clinical performance and safety of composite restorations cured with fast curing mode (5 seconds with 2000 mW/cm²) in primary molars.
- Trial name
- NCT07212660
- Testing
- Fast curing mode, Conventional curing mode
- Where
- 2 sites in Switzerland
- Volunteers
- 70 people
- Sponsor
- Ivoclar Vivadent AG
Root Caries
Evaluation of Corrective Surgery Versus Dental Implants in Compromised Upper Molars
This study seeks to assess the clinical, radiographic, and patient-reported outcomes of root amputation versus implant over a 12 months period, generating robust evidence to guide clinical decision-making and enhance patient care.
- Trial name
- NCT07608497
- Testing
- root amputation
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Caries
Zirconomer-P Versus RMGI for Proximal Restorations in Primary Molars
Clinical trial comparing two tooth-colored restorative materials for treating cavities between the teeth of primary molars in children aged 4 to 7 years.
- Trial name
- NCT07788274
- Testing
- Zirconia-fortified glass ionomer, Resin-modified glass ionomer
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Pediatric Dental General Anesthesia, Restoration
Clinical Performance and Failure Rates of Restorations Following Pediatric Dental Rehabilitation Under General Anesthesia
Full-mouth dental rehabilitation under general anesthesia (GA) is frequently required for young children with extensive dental caries, behavioral challenges, or special healthcare needs.
- Conditions
- Pediatric Dental General Anesthesia, Restoration, Clinical Performance, Full Mouth Rehabilitation
- Trial name
- NCT07827833
- Testing
- Routine Restorative Materials and Treatment Methods
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Tanta University
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth, Moringa Oleifera
Remineralization Efficacy of Moringa Oleifera Varnish Vs MI Varnish in Initial Carious Lesions Over 6 Months Follow Up: a Randomized Controlled Clinical Trial
This randomized clinical trial aimed to test the remineralization effect of laboratory prepared Moringa Oleifera based varnish compared to MI varnish (CPP-ACP) on incipient carious lesions.
- Trial name
- NCT06905379
- Testing
- Moringa Oleifera, Varnish
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Caries Risk
Validation of a Digital Caries Risk Assessment Questionnaire Against the CAMBRA Protocol in an Egyptian Adult Population
This study is designed as a cross-sectional diagnostic agreement study conducted in accordance with the Standards for Reporting Diagnostic Accuracy Studies (STARD 2015) and the Guidelines for Reporting Agreement and Precision of…
- Trial name
- NCT07716254
- Testing
- Digital Caries Risk Assessment
- Where
- Egypt
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Caries,Dental
Effect of Er,Cr:YSGG Sub-Ablative Laser Irradiation on Fissure Caries Prevention in Permanent Molars
Background: Subjecting human dental enamel to sub-ablative laser has been suggested as a novel way of caries prevention. However, further studies are needed to establish its use as a routine clinical procedure for caries…
- Trial name
- NCT06826456
- Testing
- sub-ablative Er,Cr:YSGG laser, Fluoride varnish application
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Dental Caries
Caries of First Permanent Molars and Association With Dietary and Oral Habits Among a Group of Egyptian Children
This cross-sectional study aims to assess the prevalence of dental caries in the first permanent molars of Egyptian children aged 6 to 7 years, and to examine how this caries status relates to the children's dietary habits and…
- Trial name
- NCT07725757
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Dental Caries, Dental Restoration, Permanent
Comparison of Clinical Performance of Partial Restorations Fabricated With Three-Dimensional Printer and CAD-CAM
The aim of this clinical study is to compare CAD-CAM and 3D restorations in individuals with two hard tissue losses or restorations in their mouths.
- Conditions
- Dental Caries, Dental Restoration, Permanent, Tooth Diseases
- Trial name
- NCT07031856
- Testing
- 3D printer partial crown, Treatment as usual
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Children, Dental Caries
A Comprehensive Oral Health Intervention Program for Preschool and Primary School Children in Suzhou
This study aims to evaluate the effectiveness of a comprehensive oral health intervention program among preschool and primary school children in Suzhou, China.
- Trial name
- NCT07808203
- Testing
- Comprehensive Oral Health Intervention
- Volunteers
- 2,040 people, healthy volunteers welcome
- Sponsor
- Soochow University
Dental Caries
Clinical Performance of Bioactive Bulk-Fill in Class II Restorations
This prospective split-mouth clinical study aims to compare the clinical performance of a bioactive bulk-fill composite with a conventional microhybrid composite in Class II posterior restorations.
- Trial name
- NCT07547904
- Testing
- Activa BioACTIVE Bulk Flow, Filtek Z250
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Bezmialem Vakif University
Caries,Dental, Pain
Comparative Evaluation of SMART Hall Technique Vs. Conventional SS Crown in Primary Molars: a Randomized Clinical Trial
Dental caries, particularly in primary molars, significantly affects children's oral health and overall well-being. Traditional management with stainless steel crowns (SSCs) involves significant tooth reduction and advanced…
- Conditions
- Caries,Dental, Pain, Plaque, Dental, Gingival Bleeding
- Trial name
- RCT (NCT06453005)
- Testing
- SMART Hall Technique or procedure
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- C K S Teja Institute Of Dental Sciences & Research
Dental Plaque, Dental Caries
Intraoral Scan and CBCT-Aided Diagnosis of Dental Plaque and Caries
This prospective clinical study aims to evaluate the diagnostic accuracy of intraoral scans (IOS) for the detection of dental plaque and caries.
- Trial name
- NCT07555223
- Testing
- intraoral scan
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Ghent
Oral Squamous Cell Carcinoma (OSCC), Periodontal Disease
Discovery and Validation of Biomarkers for Periodontitis, Dental Caries and Oral Squamous Cell Carcinoma
The goal of this observational study is to develop better ways to detect and predict major oral diseases, including oral cancer, gum disease, and tooth decay.
- Conditions
- Oral Squamous Cell Carcinoma (OSCC), Periodontal Disease, Dental Caries
- Trial name
- NCT07745803
- Testing
- Step 1 and 2 periodontal therapy according to the EFP clinical practice guidelines, Dental filling with or without root canal treatment, Oral cancer surgical resection including extension, dissection and reconstruction with adjunctive radiation, chemotherapy and/or biological treatments per international guidelines,
- Where
- China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University