Clinical trials: Dental Caries
Dental Caries, Dental Plaque
Comparative Effectiveness of Various Educational Approaches on Oral Hygiene
Background: Dental caries constitutes a major global public health challenge, posing substantial burdens on both oral health outcomes and healthcare systems worldwide, with far-reaching implications for prevention, treatment, and…
- Trial name
- NCT06910501
- Testing
- Traditional oral hygiene instruction, Digital slide-based education, Brush DJ mobile appliaction
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ege University
Pulpitis, Apical Periodontitis
Validation of PUFA Index in Assessing Untreated Dental Caries Among Malaysian Adult Subpopulation
PUFA Index was introduced to detect the clinical consequences of untreated dental caries. To date, there are no studies on the reliability and accuracy of the PUFA index as a screening tool.
- Trial name
- NCT04126928
- Testing
- Screening using DMFT and PUFA, orthopantomogram is taken and assessed using PAI, comprehensive clinical examination to diagnose pulpal and periapical conditions.
- Where
- Malaysia
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Dental Caries, Dental Cavities
Evaluation of Selective and Stepwise Excavation in Young Permanent Teeth With Deep Caries Lesions.
The purpose of this clinical trial is to evaluate and compare the outcomes of selective carious tissue removal versus stepwise carious tissue removal in young permanent teeth with deep carious lesions.
- Trial name
- SELECT (NCT06944028)
- Testing
- Selective excavation, Stepwise excavation
- Where
- Sweden
- Volunteers
- 666 people
- Sponsor
- Karolinska Institutet
Initial Caries, Arrested Dental Caries
Early Caries Lesion Management Observational Study
The purpose of this observational study is to assess the effectiveness of Curodont Repair Fluoride Plus (CRFP) compared to other tooth-specific treatments (silver diamine fluoride (SDF), sealants, or other FDA-approved…
- Conditions
- Initial Caries, Arrested Dental Caries, Cavitated Caries, Dental Caries
- Trial name
- ELMO (NCT04933331)
- Testing
- Curodont Repair Fluoride Plus, Silver Diamine Fluoride, Glass Ionomer Sealant
- Where
- 4 sites in United States
- Volunteers
- 744 people, healthy volunteers welcome
- Sponsor
- CareQuest Institute for Oral Health
Peri-Implantitis, Mucositis
Exploring the Relationship Among Dental Caries, Nutritional Habits and Peri-implantitis
Aim: A study was made of the prevalence, co-occurrence and association among caries, nutritional habits and peri-implant disease, with an analysis of the influence of other patient and implant factors upon peri-implant disease.
- Conditions
- Peri-Implantitis, Mucositis, Caries,Dental, Nutrition
- Trial name
- NCT04439877
- Testing
- Peri-implant disease diagnosis
- Where
- Spain
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Tooth Decay, Intellectual Disability
Probiotics in Special Needs Patients at High Risk for Tooth Decay: a Randomized Controlled Trial.
The goal of this randomized clinical trial is to test the effect orally administration of Probiotics based on Lactobacillus rhamnosus LR04 and Lactobacillus plantarum LP14 as adjuvant in caries prevention in subjects who can not…
- Conditions
- Tooth Decay, Intellectual Disability, Caries,Dental
- Trial name
- NCT06063239
- Testing
- Test Group, Positive Control, Negative Control
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- G. d'Annunzio University
Dental Caries
Caries of First Permanent Molars and Association With Dietary and Oral Habits Among a Group of Egyptian Children
This cross-sectional study aims to assess the prevalence of dental caries in the first permanent molars of Egyptian children aged 6 to 7 years, and to examine how this caries status relates to the children's dietary habits and…
- Trial name
- NCT07725757
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Dental Anxiety in Children, Dental Pain
Immersive Virtual Reality for Pain and Dental Anxiety During Pediatric Restorative Treatment
This study evaluated whether immersive virtual reality (VR) can help reduce pain and dental fear and improve behavioral cooperation in children undergoing restorative dental treatment.
- Conditions
- Dental Anxiety in Children, Dental Pain, Virtual Reality, Distraction
- Trial name
- VR-PED (NCT07781254)
- Testing
- Immersive Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- University of Gaziantep
Obesity, Dental Caries
Primary Care Beverage Study
This is a pilot randomized clinical trial of a brief educational intervention offered in primary care for Latino parents that promotes healthy beverage consumption by infants and toddlers.
- Trial name
- NCT02257203
- Testing
- Sugar Sweetened Beverage Education, Reading Education
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Caries, Dental
Effectiveness of Pit and Fissure Sealants in the Prevention of Dental Caries
This randomized clinical trial is aimed at testing the efficacy of pit and fissure sealants, in a current environmental context different from that of the seventies and eighties. It has a split mouth design.
- Trial name
- NCT00674869
- Testing
- pit and fissure sealant
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Dental Caries, Dental Caries in Children
Restoration Repairs Using Composite Resin Versus Glass Ionomer in Primary Molars: a Randomized Clinical Trial
The objective of this randomized clinical study is to evaluate the survival of repairs in restorations using composite resin (CR) or high viscosity glass ionomer cement (GIC) in primary molars.
- Trial name
- NCT04491981
- Testing
- Encapsulated Glass Ionomer Cement, Composite resin
- Where
- Brazil
- Volunteers
- 312 people
- Sponsor
- University of Sao Paulo
Dental Caries
Evaluation Of Clinical Performance of Self-adhering Flowable Composite vs Conventional Flowable Composite in Cervical Carious Lesions
This clinical trial will be conducted to compare the clinical performance of a new self-adhering flowable composite in restoring CLs compared to conventional flowable composite in geriatric patients over 12 months.
- Trial name
- NCT04475172
- Testing
- Self-Adhesive Flowable Composite
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries, Cervical
Evaluation of Low-shrinkage Giomer Versus Resin-Modified Glass Ionomer in Cervical Caries Lesions: A Clinical Trial
Management of cervical lesions presents serious problems with any restorative material. The two most common reasons for restoration failure are secondary caries at the tooth-restoration interface and loss of retention.
- Trial name
- NCT05930548
- Testing
- Low Shrinkage Giomer
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries in Children
Validation of the Arabic Version of the Caries Questionnaire
Arabic is one of the most spoken languages in the world; however, the CARIES-QC questionnaire which evaluate the effect of oral diseases and disorders on children's oral health-related quality of life has not yet been validated…
- Trial name
- NCT04882852
- Where
- Egypt
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Cairo University
Deep Dental Caries
Randomized Clinical Trial for Primary Molar Pulpotomy, Biodentine Vs Formocresol-ZOE
This is a RCT that will compare the clinical and radiographic success of pulpotomies on primary molars between the traditional technique (Formocresol/ZOE) and the new technique with Biodentine.
- Trial name
- NCT02201498
- Testing
- Pulpotomies with Formocresol/OZE and Biodentine
- Where
- Canada
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Bacterial Infections, Dental Caries
Hydrogen Peroxide Fumigation in Dental Office Environment
The study's null hypothesis posits no significant difference in bacterial levels in the dental office environment before and after implementing hydrogen peroxide (H₂O₂) fumigation.
- Conditions
- Bacterial Infections, Dental Caries, Aerosol Disease
- Trial name
- NCT06100848
- Testing
- Microbiological analysis after Caries treatment, Microbiological analysis after Caries treatment and fumigation
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Early Childhood Caries, Pediatric Disease
Clinical Performance of Composite Coronal Build -Up in Mutilated Primary Incisors: 3 Years Results
Prospective single arm study was to evaluate the clinical success and/ or failure of resin-bonded composite coronal build-up retained by macro-retentive grooves for restoring mutilated primary maxillary incisors after 36 months.
- Conditions
- Early Childhood Caries, Pediatric Disease, Dental Caries, Dental Diseases
- Trial name
- NCT04758221
- Testing
- Treatment by composite coronal build-up
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Cairo University
Dental Caries
Conventional Bite Wing Radiography Versus Stationary Intraoral Tomosynthesis, a Comparison Study
A comparison of caries detection rates between conventional intraoral bitewing radiography and a stationary intraoral digital tomosynthesis (s-IOT) using a carbon nanotube X-ray source array.
- Trial name
- NCT02873585
- Testing
- Stationary intraoral tomosynthesis, Standard conventional bitewing radiography
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Congenital Heart Defect, Dental Caries in Children
Oral Health Intervention Program for Children With Congenital Heart Defects
Background: Children with congenital heart defects (CHD) are reported to have poorer oral health compared with healthy children.
- Conditions
- Congenital Heart Defect, Dental Caries in Children, Dental Erosion, Dental Plaque
- Trial name
- NCT03311438
- Testing
- Oral health intervention program
- Volunteers
- 75 people
- Sponsor
- University of Bergen
Dental Caries, Teeth Loss
The Effect of Bitewing Radiography on Outcomes and Costs of Treating Caries in Permanent Teeth
Dentists commonly use bitewing radiographs (dental X-rays) together with a visual-tactile (clinical) examination to detect cavities between the back teeth.
- Conditions
- Dental Caries, Teeth Loss, Necrosis of Pulp, Irreversible Pulpitis
- Trial name
- BROCC (NCT07882693)
- Testing
- Visual-tactile caries examination, Visual-tactile caries examination and bilateral bitewing radiography
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jukka Leinonen
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