Clinical trials: Dental Decay
Class II Dental Caries, Dental Caries
Comparison of the Functional Properties of Two Injectable Materials in Posterior Teeth: Randomized Clinical Trial
Using two different injectable materials in class II cavities to compare functional properties
- Conditions
- Class II Dental Caries, Dental Caries, Injectable Composite
- Trial name
- NCT06894186
- Testing
- Gaenial universal injectable
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
White Spot Lesion of Tooth, Long Term Adverse Effects
Comparison of Efficacy Of Probiotic Toothpaste and Chlorhexidine Mouthwash To Reduce S.Mutans
Orthodontic appliance causes increase in plaque accumulation, especially around brackets, wires and attachments. Advances in orthodontics in recent time have led to improved quality of appliance and treatment procedures…
- Conditions
- White Spot Lesion of Tooth, Long Term Adverse Effects, Caries, Dental, Orthodontic Appliance Complication
- Trial name
- NCT03004196
- Testing
- Probiotic Toothpaste, Dr. Reddy's Clohex, Control Group
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peoples University, Bhanpur, Bhopal
Dental Caries, Periodontitis
Breaking the Cycle: Real-Time Family Oral Microbial Transmission Patterns as Intervention Targets
This study aims to understand how oral bacteria that cause tooth decay and gum disease spread among family members and whether treating multiple family members can reduce the return of these bacteria after dental treatment.
- Conditions
- Dental Caries, Periodontitis, Oral Microbiome, Bacterial Transmission
- Trial name
- NCT07674888
- Testing
- Professional Dental Plaque Disruption
- Where
- Canada
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Dental Caries, Prevention
Sealant Application by Interns After Tele-demonstration
Abstract Background: Dental caries remains a major public health issue worldwide, particularly among children. Pit and fissure sealants represent a high-quality, evidence-based preventive measure.
- Conditions
- Dental Caries, Prevention, Education
- Trial name
- TESS (NCT07232797)
- Testing
- tele-demonstration, traditional demonstration group
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Caries Class I (Disorder), Dental Caries Class II
Clinical Evaluation of Bulk-fill vs Layered Composite Resin in Class I and II Posterior Restorations
The aim of this study is to evaluate the clinical performance of Filtek Bulk Fill Posterior Restorative in Class I and Class II restorations compared to the conventional incremental technique using Filtek Z350XT over the period…
- Trial name
- NCT03306602
- Testing
- Filtek Bulk Fill Posterior Restorative, Filtek Z350 XT
- Where
- Malaysia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
Dental Caries, Child Neglect
Improving Family's Adherence to Dental Care After DGA (HECC-CAN-study)
Early childhood caries (ECC) is a common disease. Its prevalence is highest in poor, socially disadvantaged, and minority groups. Dental treatment under General Anaesthesia (DGA) is common, especially among the youngest patients.
- Trial name
- HECC-CAN (NCT04898465)
- Testing
- Social Paediatric Intervention
- Where
- Finland
- Volunteers
- 89 people
- Sponsor
- Helsinki University Central Hospital
Dental Caries
Effectiveness of Modified Class IV Atraumatic Restorative Treatment
Atraumatic Restorative Treatment (ART) has become an accepted dental restoration treatment in many developing countries. Because, ART is intended to be operated in molars, and about 10% of all carious lesion by an age of 18 years…
- Trial name
- modARTIV (NCT02234609)
- Testing
- modified ART class IV
- Where
- The Gambia
- Volunteers
- 69 people
- Sponsor
- University of Witten/Herdecke
Dental Caries in Children
Cost-effectiveness of Topical Fluoride in Preventing Deciduous Dental Caries in Preschool Children
Fluoride foam and fluoride varnish are effectiveness in prevention deciduous dental caries. However, the relative clinical efficacy and cost-effectiveness of these two interventions are uncertain.
- Trial name
- NCT05025163
- Testing
- 1.23% fluoride foam application, 2.26% fluoride varnish application
- Volunteers
- 1,083 people
- Sponsor
- National Center for Chronic and Noncommunicable Disease Control and Prevention, China CDC
Early Childhood Caries, Pediatric Disease
Clinical Performance of Composite Coronal Build -Up in Mutilated Primary Incisors: 3 Years Results
Prospective single arm study was to evaluate the clinical success and/ or failure of resin-bonded composite coronal build-up retained by macro-retentive grooves for restoring mutilated primary maxillary incisors after 36 months.
- Conditions
- Early Childhood Caries, Pediatric Disease, Dental Caries, Dental Diseases
- Trial name
- NCT04758221
- Testing
- Treatment by composite coronal build-up
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Cairo University
Dental Caries, Oral Bacterial Infection
Ecological Effect of Arginine Dentifrice on Oral Microbiota
caries-free (CF) individuals caries-active (CA) individuals (DMFT ≥ 6) will be recruited. Subjects will be instructed to brush their teeth twice daily for 3 min using Colgate® Sensitive Pro-Relief® toothpaste (containing 8%…
- Conditions
- Dental Caries, Oral Bacterial Infection, Microbiota
- Trial name
- NCT02988349
- Testing
- Colgate® Sensitive Pro-Relief® toothpaste
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sichuan University
Periodontitis, Dental Caries
Immediate Implant Placement in the Molar Regions
The purpose of this study is to look at the bonehealing when a molar has been extracted and immediately replaced by an implant leaving some defects around the implant.
- Conditions
- Periodontitis, Dental Caries, Periapical Periodontitis
- Trial name
- NCT00226148
- Testing
- Use of a membrane to cover bonedefects around implant, Use of bonechips to fill up defects around implant, Use of membrane and bonechips to manage defects
- Where
- Denmark
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Carious Teeth
Clinical Performance of One-shade Universal Dental Resin Composite as Posterior Restoration
This study is aimed to evaluate the clinical performance of new One-shade universal composite resin as posterior restoration using US Public Health Service "USPSH" criteria for color match, marginal adaptation, surface texture…
- Trial name
- NCT05500547
- Testing
- US Public Health Service "USPSH" criteria for assessment of success of resin composite restorations
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Minia University
Dental Caries, Dental Plaque
The Effect of Arginine on Biofilm Composition, Architecture and Metabolism
Arginine is an adjunct to oral health care that has the potential to modulate the composition and activity of the microbial community of dental biofilms towards a health-related status without harmful effects for the resident…
- Conditions
- Dental Caries, Dental Plaque, Microbial Colonization
- Trial name
- NCT06135792
- Testing
- Arginine
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Caries, Dental
Anterior Zirconia vs. Resin Strip Crowns
This study is comparing the effectiveness of two different dental crown fillings (resin crowns and zirconia crowns) for primary front teeth (incisors).
- Trial name
- NCT03889535
- Testing
- Resin strip crowns, Zirconia crowns
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- The Hospital for Sick Children
Dental Caries, Denture, Partial, Removable
Nobio Clinical Study - Demineralization Prevention With a New Antibacterial Restorative Composite
Nobio has developed dental restorative materials with long term antibacterial properties in order to fight recurrent decay/caries around restorations.
- Trial name
- Nobio (NCT04059250)
- Testing
- Nobio composite, traditional composite
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dental Caries
Efficacy of Two Protocols for Applying Fluorine Varnish to Deciduous Teeth
Evidence that the data flow analysis tests, there are still no studies that show the clarity of the protocols of its application, including the interval and execution factors of applications, concentration of fluoridation and…
- Trial name
- CEPECO3 (NCT03827889)
- Testing
- WMP of fluoride varnish, TWLP of fluoride varnish, DHP (educational intervention)
- Where
- Brazil
- Volunteers
- 168 people
- Sponsor
- Universidade Ibirapuera
Abrasion, Dental, Class I Dental Caries
Performance Of Class I Composite Restorations After Cavity Finishing By Air Abrasion Versus Diamond Stone
The aim of the study is to reveal the performance of the resin composite restorations after finishing the cavity walls and margins using bioactive glass air abrasion particles in comparison to the routine finishing with the…
- Trial name
- NCT06107218
- Testing
- Bioactive Glass Air Abrasion Particles., Diamond Stone.
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Probiotics That Moderate pH and Antagonize Pathogens to Promote Oral Health
This study will examine the mechanisms of action of probiotics and synbiotics for control of oral diseases, with a particular focus on exploring new strategies for caries prevention and treatment.
- Trial name
- NCT02999230
- Testing
- Caries Free 1.5% Arginine, Caries Active 1.5% Arginine
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Florida
Dental Caries
A Clinical Study to Evaluate Experimental Children's Toothpastes in an In-Situ Caries Model
An in situ model will be used to evaluate and compare enamel remineralization of human enamel specimens after single use of experimental children's toothpastes.
- Trial name
- NCT01607411
- Testing
- Fluoride
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dental Caries in Children, Early Childhood Caries
Effect of Optimized Behavioural Intervention Using The Multi-Phase Optimization Strategy (MOST).
In the current study, MOST approach is proposed, to engineer an oral health behavior modification intervention, to increase the engagement of mothers in brushing their pre-school children's teeth.
- Trial name
- NCT04923581
- Testing
- Oral Health Behavioral Interventions
- Where
- 2 sites in Egypt
- Volunteers
- 128 people
- Sponsor
- Merna Ihab