Clinical trials: Dental Developmental Disorders and Anomalies
Molar Incisor Hypomineralization, Asthma in Children
Prevalence of Molar Incisor Hypomineralization Among Children Treated With Asthmatic Drugs Early in Their Lives
The aim of this study is to assess the prevalence of molar incisor hypo mineralization among children who have been treated with asthmatic drugs during the first three years of life.
- Trial name
- NCT04103710
- Where
- Egypt
- Volunteers
- 167 people
- Sponsor
- Cairo University
Molar Incisor Hypomineralisation
Molar Incisor Hypomineralisation and Dental Anomalies
Background/study aim: Molar incisor hypomineralisation (MIH) is a common disorder of tooth development. Affected teeth have weak enamel and adult molars often require extensive treatment or even extraction.
- Trial name
- NCT05812690
- Testing
- This is a non intervention - observation only study
- Where
- United Kingdom
- Volunteers
- 1,279 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Children, Adult, Molar Incisor Hypomineralization
Effectiveness of Infiltration With Resin in Treatment of MIH Incisors in Children Showing Opacities
Enamel development defects are the result of a set of environmental, systemic and genetic causal agents that reveal a multifactorial etiology model, which in anterior teeth produces a serious aesthetic problem, converted into a…
- Conditions
- Children, Adult, Molar Incisor Hypomineralization, Dental Diseases, Opacity
- Trial name
- NCT05597956
- Testing
- white defects, yellow defects, brown defects
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- University of Valencia
Healthy Individuals
Fluoride Intake From Toothbrushig With Children's or Regular Toothpastes
There are controversial data about fluoride intake by children when tooth brushing with children's or regular toothpastes. However, a study have showed that children were exposed to a dose of 0.051 mg F/Kg/day and 0.046 mg…
- Trial name
- F (NCT01568541)
- Testing
- Regular toothpastes, Children's toothpastes
- Where
- 3 sites in Brazil
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Molar Incisor Hypomineralization
Assessment of the Remineralization Efficacy of Vitamin D in the Treatment of MIH. In Vitro Study and In Situ Randomized Double-Blind Placebo Clinical Trial.
In child patients with molar incisor hypo mineralization, Will Vitamin D mouth wash offer more success for patients with MIH as regards better MIH TNI index, decrease plaque accumulation, more gingival health and less bleeding on…
- Trial name
- NCT06515548
- Testing
- Vitamin D3 mouth wash
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Enamel Hypoplasia, Dental Caries
Evaluation Direct and Indirect Composite Restoration in Hypomineralization Molars.
The aim of this study is to evaluate the effectiveness of direct and Indirect Composite Restoration in Children With Molar Incisor Hypomineralization Patients (MIH) and following up after 3 , 6 , 12 months (Clinically): Group A …
- Trial name
- NCT05299489
- Testing
- Direct restoration, Indirect restoration
- Where
- Syria
- Volunteers
- 20 people
- Sponsor
- Damascus University
Hypomineralization of Enamel
PMCs as a Treatment of Children With HSPM Using the HT
Hypomineralised primary second molars are primary molars with a developmental disorder of the enamel. Preformed metal crowns already have good results for the treatment of caries on primary molars.
- Trial name
- NCT04265183
- Testing
- Placing preformed metal crowns using Hall technique.
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Tooth Demineralization, Tooth Sensitivity
Graphene-Reinforced CAD/CAM Restorations for MIH-Affected Molars in Adolescents: A Prospective Clinical Study
This study evaluates the clinical performance, marginal integrity, surface wear, color stability, and postoperative sensitivity of graphene-reinforced CAD/CAM indirect restorations (inlays, onlays, overlays) in molars affected by…
- Conditions
- Tooth Demineralization, Tooth Sensitivity, Enamel Mineralization Disorders, Tooth Sensitivity After Composite Restorations
- Trial name
- NCT07329244
- Testing
- Graphene-reinforced CAD/CAM polymer (G-CAM®)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universitat Internacional de Catalunya
Molar Incisor Hypomineralisation
Effect of Nano Hydroxy Apatite Varnish and Potassium Nitrate Gel on the MIH-affected Permanent Teeth
This clinical study main goal is to investigate the effectiveness of nano hydroxy apatite crystal varnish and potassium nitrate gel as a non invasive approach in managing MIH-affected teeth.
- Trial name
- NCT06896565
- Testing
- nano hydroxy apatite varnish, Potassium Nitrate Gel, Varnishes, Fluoride
- Volunteers
- 48 people
- Sponsor
- Cairo University
Amelogenesis Imperfecta, Dental Caries
Clinical Performance of Composites in Patients With Amelogenesis Imperfecta
In AI patients, adhesion still remains the first option in order to achieve an early, minimally invasive intervention, and the altered enamel still represents an acceptable substrate for bonding in some AI variants.
- Conditions
- Amelogenesis Imperfecta, Dental Caries, Dental Composite
- Trial name
- NCT04897724
- Testing
- dental composite
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Neslihan Tekçe
Molar Incisor Hypomineralisation
Etch-bleach-seal Technique in Managing Opacities Related MIH Using Icon®
Objectives: to compare aesthetic effectiveness of resin infiltration with/without using sodium hypochlorite in managing opacities of MIH on incisors, and to compare parent's satisfaction with results of both application…
- Trial name
- NCT07162077
- Testing
- Sodium hypochlorite 5.25%, ICON resin infiltration Material group in vivo
- Where
- Syria
- Volunteers
- 15 people
- Sponsor
- Latakia University
Molar Incisor Hypomineralisation, Molar Incisor Hypomineralization
Prevalence of Hypomineralized Second Primary Molars and Its Association with Molar-Incisor Hypomineralization.
The aim for thid study is to detect the prevalence of HSPM and the possible association between MIH and HSPM in a group of Egyptian children aged from 6-12 years.
- Conditions
- Molar Incisor Hypomineralisation, Molar Incisor Hypomineralization, Hypomineralization Molar Incisor, Hypomineralization of Enamel
- Trial name
- NCT06727539
- Volunteers
- 825 people
- Sponsor
- Cairo University
Molar Incisor Hypomineralization
Clinical Evaluation of Resin Infiltration Treatment of MIH-affected Teeth in Pediatric Patients
The goal of this clinical trial is to examine the clinical success of different pre-treatments in resin infiltration therapy applied to the incisors of pediatric patients with Molar Incisor Hypomineralization (MIH) and to…
- Trial name
- NCT07469124
- Testing
- Resin Infiltration, Microabrasion Followed by Resin Infiltration, Air Abrasion Followed by Resin Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Inonu University
Fluoride Varnishes, Molar Incisor Hypomineralisation
Nanohydroxyapatite Versus Sodium Fluoride Varnish in Remineralizing MIH Anterior Teeth
This randomized controlled clinical trial evaluates and compares the remineralization efficacy of a 8.6% nanohydroxyapatite (nano-HAp) varnish versus a standard 5% sodium fluoride (NaF) varnish in young permanent anterior teeth…
- Conditions
- Fluoride Varnishes, Molar Incisor Hypomineralisation, Permanent Anterior Teeth, Remineralization
- Trial name
- NCT07894510
- Testing
- Nanohydroxyapatite Varnish Application, Sodium Fluoride Varnish Application
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Tanta University
Molar-Incisor Hypomineralization (MIH)
Assessment of Peridontal Inflamatuar Markers in MIH
The goal of this observational study is to investigate periodontal inflammatory mediators in systemically healthy children aged 8-13 years with and without molar-incisor hypomineralization (MIH) who require initial periodontal…
- Trial name
- NCT07701642
- Testing
- Initial periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Marmara University
Molar Incisor Hypomineralization
Change in OHRQOL Following Minimally Invasive Treatment of Anterior Teeth in Children With MIH
MIH is a prevalent developmental defect which has a negative impact on children's OHRQoL, especially when incisor opacities are present.
- Trial name
- NCT05727475
- Testing
- Minimal invasive restorative treatment, Fluoride gel application
- Where
- Jordan
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Molar Incisor Hypomineralisation, Children
This Study Aims to Evaluate the Effect of Rinsing Off or Blot-drying Silver Fluoride on the Retention of Subsequently-applied Resin- and Glass Ionomer-based Fissure Sealants in Permanent Molars Affected by Molar-Incisor Hypomineralization.
The aim of this study is three-fold: 1. To evaluate the clinical performance of glass ionomer fissure sealants and resin fissure sealants when placed immediately after or one week following the application of silver fluoride on…
- Conditions
- Molar Incisor Hypomineralisation, Children, Dental Caries
- Trial name
- NCT06641011
- Testing
- Immediate restoration (resin- based) after blot-drying silver fluoride application, Immediate restoration (GI- based) after blot-drying silver fluoride application, Immediate restoration (Resin based) after rinsing silver fluoride application
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Hypomineralization Molar Incisor
Photobiomodulation and Glass Ionomer Sealant as Complementary Treatment for Hypersensitivity in Molars With MIH
Introduction: Photobiomodulation (PBM) shows promising results for the complementary treatment of dentin hypersensitivity; however, few studies have evaluated this treatment specifically for teeth affected by molar incisor…
- Trial name
- NCT05370417
- Testing
- Use of fluoride toothpaste, Photobiomodulation, Simulated Laser Therapy
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Molar Incisor Hypomineralization
Knowledge Regarding Diagnosis of MIH Among Dental Interns in Faculty of Dentistry Cairo University
assessment of knowledge of dental interns regarding diagnosis of MIH among Group of interns in faculty of dentistry Cairo university
- Trial name
- NCT04030936
- Volunteers
- 190 people
- Sponsor
- Cairo University
Molar Incisor Hypomineralization
Restoration Quality in Molars Affected by Molar Incisor Hypo Mineralization
Restoration quality of molars affected by MIH using two different types of restorations direct composite and preformed crowns
- Trial name
- NCT04475419
- Testing
- preformed stainless steel crowns cemented by glass ionomer luting cement(Ketac Cem, 3M Espe)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University