Clinical trials: Dental Developmental Disorders and Anomalies
Molar Incisor Hypomineralization
Knowledge Regarding Diagnosis of MIH Among Dental Interns in Faculty of Dentistry Cairo University
assessment of knowledge of dental interns regarding diagnosis of MIH among Group of interns in faculty of dentistry Cairo university
- Trial name
- NCT04030936
- Volunteers
- 190 people
- Sponsor
- Cairo University
Osteogenesis Imperfecta, Rare Bone Disorders
Morphology in Oral Rare Syndromes & Artificial Intelligence for Clinical Diagnosis
MOSAIC aims to determine whether oro-dental morphological anomalies, particularly palatal morphology, associated with rare bone and cartilage diseases can be precisely characterized using 3D digital models analysed through…
- Conditions
- Osteogenesis Imperfecta, Rare Bone Disorders, Hypophosphatemia, X-Linked
- Trial name
- MOSAIC (NCT07666269)
- Testing
- intra-oral 3D optical impression
- Where
- France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Molar-Incisor Hypomineralization
Evaluation of Different Anesthesias in Children With Molar Incisor Hypomineralization
In children with molar-incisor hypomineralization (MIH), insufficient depth of anesthesia can lead to increased anxiety and behavior management problems, which may negatively affect the quality of restorations.
- Trial name
- NCT07268157
- Testing
- Computer-controlled anesthesia device (SleeperOne), Conventional injection technique
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Canan Bayraktar Nahir
Molar Incisor Hypomineralization
Local Anesthesia in Molar Teeth With Molar Incisor Hypomineralization
To compare responses to electrical pulp test (EPT) and cold test among molar incisor hypomineralization (MIH)-effected and not MIH-effected carious teeth before and after administration of local anesthesia for caries removal.
- Trial name
- NCT04061096
- Testing
- Evaluation of cold test, Evaluation of electrical pulp test, Evaluation of pain during the treatment
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Didem Sakaryali
Molar Incisor Hypomineralization
Prevalence of MIH Among Group of Egyptians Children Aged From 8 to 12 in Damietta
Assesment of the prevalence of molar incisor hypomineralization among a group of egyptian children aged from 8 to 12 years old in Damietta governate.
- Trial name
- NCT04410172
- Testing
- Mirror and prope
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Eman Zakaria Ali Hashem
Molar-Incisor Hypomineralization
Clinical Efficacies of Different Agents in Molar-Incisor Hypomineralization
This study aims to assess the clinical effectiveness of GC Fuji Triage ® (GC America Inc., Alsip, Illinois) and BeutiSealant (Shofu, Kyoto, Japan) in children aged 8-13 with multiple molars affected by Molar-Incisor…
- Trial name
- NCT06180369
- Testing
- GC Fuji Triage ® GC America Inc., Alsip, Illinois ), BeutiSealant (Shofu, Kyoto, Japonya)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Marmara University
Sensitive Dentin, Hypomineralization Molar Incisor
BIOSILITACE AS A DESENSITIZING AGENTIN HMI
Molar-Incisor Hypomineralization (MIH) is a qualitative enamel defect caused by systemic hypomineralization that affects one to four first permanent molars, and may or may not involve incisors.
- Conditions
- Sensitive Dentin, Hypomineralization Molar Incisor, Pain
- Trial name
- BDAHMI (NCT07080645)
- Testing
- Pain Relieving, topical application
- Where
- 2 sites in Brazil
- Volunteers
- 42 people
- Sponsor
- University of Sao Paulo
Molar Incisor Hypomineralisation
Correlation Between Colour and Hypersensitivity of First Permanent Molars With Molar Incisor Hypomineralisation (MIH)
Cheese molars (MIH: molar incisor hypomineralisation) can be recognized not only by their colour abnormalities but also by their hypersensitivity.
- Trial name
- NCT07727044
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Basel
Hypomineralization of Enamel
PMCs as a Treatment of Children With HSPM Using the HT
Hypomineralised primary second molars are primary molars with a developmental disorder of the enamel. Preformed metal crowns already have good results for the treatment of caries on primary molars.
- Trial name
- NCT04265183
- Testing
- Placing preformed metal crowns using Hall technique.
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Molar Hypomineralization, Dental Restoration Failure of Marginal Integrity
CAD-CAM or Adhesive Approaches for MIH Treatment
Aim: This randomized controlled clinical study aimed to compare direct composite resin restorations and Computer Aided Design-Computer Aided Manufacturing (CAD-CAM) supported inlay or onlay restorations in young permanent molar…
- Trial name
- NCT06456619
- Testing
- Tooth restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Baskent University
Molar Incisor Hypomineralisation
Intraosseous Anesthesia in MIH-Affected Teeth
Managing MIH-affected teeth is challenging due to inflammation, sensitivity, rapid caries development, and difficulty achieving anesthesia.
- Trial name
- IO-MIH (NCT07457450)
- Testing
- Intraosseous anesthesia., Local infiltration anesthesia
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- University of Zagreb
Molar Incisor Hypomineralization
Prevalence And Severity Of Molar Incisor Hypomineralization Among A Group Of Children With Type I Diabetes Milletus.
Determine the prevalence of molar incisor hypomineralization among a group of children with type I diabetes millutes, its severity and treatment need via clinical examination of children with type I diabetes millutes .
- Trial name
- NCT06342089
- Testing
- Type I diabetes milletus
- Volunteers
- 238 people
- Sponsor
- Cairo University
Dental Fluorosis
Systemic Fluoride Bioavailability From Toothpastes Containing Calcium Carbonate or Silica as Abrasives
The risk of dental fluorosis development is related to the systemic exposure to fluoride during enamel formation. Currently, diet and fluoride toothpastes are the main sources of fluoride to children at the age-risk for fluorosis…
- Trial name
- NCT01571050
- Testing
- Purified water, Fresh MFP/CaCO3 toothpaste, Fresh NaF/SiO2 toothpaste
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Hypomineralization Molar Incisor
Photobiomodulation and Glass Ionomer Sealant as Complementary Treatment for Hypersensitivity in Molars With MIH
Introduction: Photobiomodulation (PBM) shows promising results for the complementary treatment of dentin hypersensitivity; however, few studies have evaluated this treatment specifically for teeth affected by molar incisor…
- Trial name
- NCT05370417
- Testing
- Use of fluoride toothpaste, Photobiomodulation, Simulated Laser Therapy
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Osteogenesis Imperfecta
Dental Malocclusion and Craniofacial Development in OI
Osteogenesis imperfecta (OI) is a rare inherited disorder that causes bones to break easily. Individuals with osteogenesis imperfecta break bones often and may have other problems, including hearing loss and pain and difficulty…
- Trial name
- NCT02934451
- Where
- 3 sites in United States, Canada
- Volunteers
- 75 people
- Sponsor
- Baylor College of Medicine
Molar Incisor Hypomineralization
Computer-aided Design/Computer-aided Manufacturing for Mild to Moderate Molar Incisor Hypomineralization Treatment
Molar Incisor Hypomineralization (MIH) is a disease causing a structural defect in the enamel of permanent teeth. The treatment of these teeth consists of the removal of the affected part of the tooth and its reconstitution.
- Trial name
- MIhCFAO (NCT04922177)
- Testing
- Indirect ceramic restoration, Direct restoration
- Where
- France
- Volunteers
- 68 people
- Sponsor
- University Hospital, Toulouse
Dental Fluorosis, Dental Caries
Effect of pH and Fluoride Concentration of Dentifrices on Caries Control
This study aims to assess the overall effect of pH and fluoride concentration of liquid dentifrices in the control of children dental caries of a fluoridated area, through visual inspection and the quantitative light-induced…
- Trial name
- EPHFCDCC (NCT01049503)
- Testing
- Low fluoride and conventional dentifrices with different pH
- Where
- Brazil
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
White Spot Lesion, Enamel Hypomineralization
Evaluation of CPP-ACP Prophylactic Effect on Enamel Surface During Orthodontic Treatment
This study is aiming in preventing the formation of WSL associated with orthodontic treatment which occurs to more than 50% of orthodontically treated patients through applying CPP-ACP on the enamel surface once every 2 weeks for…
- Trial name
- NCT03187548
- Testing
- Casein Phosphopeptide-Amorphous Calcium Phosphate Dental Paste
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Molar Incisor Hypomineralization
Comparative Evaluation of Giomer Varnish vs Fluoride Varnish as Desensitizing Agents in Teeth With MIH
this clinical trial's aim is to compare two desensitizing agents available in the market to prove which one is more efficient in children with molar incisor hypomineralization complaining from hypersensitivity
- Trial name
- NCT05542667
- Testing
- Giomer varnish, Fluoride varnish
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Molar Incisor Hypomineralization
Zirconia Versus Lithium Di-silicate Overlays for Restoring Hypomineralized Molars Affected With MIH
the study evaluate the clinical outcome of zirconia versus lithium disilicate overlays restorations for restoring vital young permanent first molar teeth affected with moderate form of molar Incisor hypomineralization: randomized…
- Trial name
- NCT05529329
- Testing
- overlay
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Al-Azhar University