Clinical trials: Dental Disease
Post-surgical Dental Pain
Post-operative Dental Pain Study Comparing Two Different Dosage of Analgesic Efficacy
GlaxoSmithKline will be conducting this trial to compare analgesic efficacy of paracetamol 1000 mg vs 650 mg. The post-surgical dental pain model will be used to evaluate the analgesic efficacy of paracetamol.
- Trial name
- NCT01075243
- Testing
- Paracetamol 1000 mg, Paracetamol 650 mg
- Where
- United States
- Volunteers
- 401 people
- Sponsor
- GlaxoSmithKline
Pulp Disease, Dental
Evaluation of Success Rate of Partial Pulpotomy Versus Complete Pulpotomy in Primary Molars Using NeoPUTTY MTA
Evaluating the clinical and radiographic success of partial pulpotomy compared to complete pulpotomy in vital primary second molars with reversible pulpitis using NeoPUTTY™ (MTA).
- Trial name
- NCT06524076
- Testing
- Partial Pulpotomy, Complete pulpotomy
- Volunteers
- 60 people
- Sponsor
- Cairo University
Periodontitis, Gingivitis
Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose Control
The goal of this study is to learn if dental infection control treatment delivered to older adult nursing home residents at their place of residence will result in : improved dental health reduced risk of pneumonia better glucose…
- Conditions
- Periodontitis, Gingivitis, Periodontal Disease, Periodontal Infections
- Trial name
- NHOralHealth (NCT06890676)
- Testing
- Comprehensive Oral Evaluation, Intraoral Complete Radiographic Series, • Teledentistry-synchronous and asynchronous
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Missouri Department of Health and Senior Services
Alveolar Bone Loss, Alveolar Ridge Pathology | Gingiva | Dental
Comparative Study of Gene-activated Bone Substitute and Xenogenic Bone Matrix in Alveolar Ridge Augmentation
The study aim is to compare the effectiveness of two bone substitutes, the gene-activated bone substitute based on octacalcium phosphate and plasmid DNA encoding VEGFA gene and xemogenic deproteinized bone matrix, mixed with…
- Trial name
- NCT04511689
- Testing
- gene-activated bone substitute mixed with autobone
- Where
- Russia
- Volunteers
- 24 people
- Sponsor
- Histograft Co., Ltd.
Nitrous Oxide, Dentistry
Demand-Driven Method for Gas Delivery in a Dental Setting
This study compares two methods of gas delivery in a dental setting: 1) demand-driven (DD) and 2) free-flow (FF). Nitrous oxide and oxygen sedation (NOS) is a common form of minimal sedation for adult and paediatric patients…
- Conditions
- Nitrous Oxide, Dentistry, Drug Delivery System, Comfort
- Trial name
- NCT04305990
- Testing
- Demand-driven delivery method, Free-flow delivery method
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Pulpitis, Caries Active
Hydraulic Cements in Partial Pulpotomy
This study is a randomized clinical trial that compares two types of hydraulic cements used in partial pulpotomy procedures for permanent teeth affected by deep decay and pulp inflammation.
- Trial name
- NCT06881615
- Testing
- MTA PLACEMENT FOR PP, PUTTY PLACEMENT FOR PP
- Where
- Spain
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Dental Caries
Retention and Caries Prevention of Giomer Sealant With or Without Diode Laser Pre-treatment: A Randomized Controlled Trial
This randomized controlled trial evaluates the effect of diode laser pre-treatment on the retention and caries prevention of giomer-based fissure sealants in young adults aged 17-22 years.
- Trial name
- NCT07612540
- Testing
- phosphoric acid pretreatment
- Where
- 3 sites in Egypt
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Sequential PVP-I and FV
This prospective cohort study in children will determine if: topical povidone iodine 10% followed by topical fluoride varnish is superior to placebo iodine followed two different varnishes alone to prevent tooth decay (dental…
- Trial name
- NCT07683910
- Testing
- fluoride varnish, 2.5%, topical fluoride, 2.1%, Povidone Iodine Topical
- Volunteers
- 393 people, healthy volunteers welcome
- Sponsor
- Advantage Silver Dental Arrest, LLC
Dental Caries, Insufficient Dental Filling
A Clinical Trial to Compare the Safety and Performance of Two Different Curing Modes in the Direct Filling Therapy in Deciduous Teeth
The overall aim of this clinical investigation is to assess the clinical performance and safety of composite restorations cured with fast curing mode (5 seconds with 2000 mW/cm²) in primary molars.
- Trial name
- NCT07212660
- Testing
- Fast curing mode, Conventional curing mode
- Where
- 2 sites in Switzerland
- Volunteers
- 70 people
- Sponsor
- Ivoclar Vivadent AG
Dentin Sensitivity
Clinical Evaluation of Polycation-based New Dental Desensitizer on Dentin Hypersensitivity
Evaluate the safety and clinical efficacy of new dental desensitizers in the treatment of dentin sensitivity, including the relief of sensitivity symptoms and the duration of efficacy.
- Trial name
- NCT06378255
- Testing
- Polycation-based new dentinal desensitizer, GLUMA desensitizer
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University Hospital of Stomatology
Pulpal Necrosis
Evaluation of Chitosan as Irrigating Solution for Pulpectomy in Non-Vital Primary Teeth
45 teeth will be sub-divided at random with a computerized method, according to the type irrigant and duration of its application into 3 groups (15 teeth in each group): Group1(control group): The teeth will be irrigated by 2 ml…
- Trial name
- NCT06506526
- Testing
- Sodium hypochlorite irrigating solution, one minute NaOCL+Chitosan, Three minute NaOCL+Chitosan
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Suez Canal University
PERIODONTAL DISEASE
Dental Engagement Study Behavior Modification
This is a pilot study to determine whether knowledge gained by an individual of genetic risk for severe periodontitis changes the patient's health behavior as measured by an increased frequency of their preventive dental office…
- Trial name
- NCT02749318
- Testing
- IL-1 genetic test for risk of severe periodontitis
- Sponsor
- Interleukin Genetics, Inc.
Gingivitis, Dental Plaque
"Safeguard Your Smile" an Oral Health Literacy Intervention Promoting Positive Oral Hygiene Self-care Behavior
The purpose of the investigators' study is to assess effectiveness of community based oral health literacy intervention promoting positive oral hygiene self-care behavior among Montreal's Punjabi immigrants.
- Trial name
- NCT02521155
- Testing
- Safeguard Your Smile an oral health literacy intervention
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Dental Caries, Dental Plaque
Study of the Composition of Dental Plaque
This study will examine the composition of dental plaque-a naturally occurring substance that sticks to the teeth and can cause tooth decay and gum disease.
- Conditions
- Dental Caries, Dental Plaque, Periodontal Disease
- Trial name
- NCT00001726
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Gingivitis
Comparing the Inter-dental Brush to Dental Floss
The study's purpose is to find an easy and effective alternative to dental floss for those persons who cannot or choose not to dental floss so that they can maintain and/or achieve optimal oral health.
- Trial name
- NCT00743548
- Testing
- IB = Interdental brush, the intervention, DF = Dental floss, the positive control
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Obesity, Water; Lack of
Preventing Early Childhood Obesity, Part 1: Family Spirit Nurture, 3-9 Months
This study aims to assess the impact of a brief home-visiting module, called "Family Spirit Nurture" (FSN), on American Indian (AI) parent feeding practices associated with increased risk for early childhood obesity, with a…
- Conditions
- Obesity, Water; Lack of, Breast Feeding, Tooth Erosion
- Trial name
- NCT03101943
- Testing
- Family Spirit Nurture (FSN), Control Program, Water Delivery
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Dental Caries
Consumption Effect of Probiotic Products on Salivary Cariogenic Bacterial Counts in Preschool Children.
The purpose of this study is to evaluate the efficacy of probiotic products on caries-associated salivary bacterial counts (Streptococcus mutans and Lactobacillus) and its effect on dental plaque accumulation in a group of…
- Trial name
- NCT02692625
- Testing
- (L. reuteri Prodentis®).
- Where
- Saudi Arabia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Jaw, Edentulous
Accuracy of Computer Guided Implant Surgery
The investigators' aim is to evaluate the accuracy of the stereolitographic template comparing the final implant insertion to the planned implant position at coronal and apical level.
- Trial name
- STIMPLANTSRG (NCT02418117)
- Testing
- Stereolitographic template
- Where
- Romania
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Concordia Dent Srl
Dental Caries, Tooth Discoloration
Color Stability of Darkly Discolored Arrested Caries Lesions Following Bleaching Treatment
This observational study evaluated the color stability of darkly discolored arrested caries lesions (DDACL) on anterior teeth following in-office bleaching with 40% hydrogen peroxide, in comparison with healthy teeth.
- Trial name
- NCT07886255
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Dental Caries
Association Between Primary School Children's Speaking Attitudes and Oral Health Indicators
his cross-sectional study aims to evaluate the relationship between primary school children's speaking attitudes and oral health indicators, including dental caries, malocclusion, and tooth loss.
- Trial name
- NCT07271810
- Testing
- Observational Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Ezgi Turkyilmaz