Clinical trials: Dental Diseases
Dental Caries
Effect of Photodynamic Therapy With Low-level Laser on Infected Dentin in Primary Teeth: A Controlled Clinical Trial
The aim of the proposed study is to assess the clinical effect of photodynamic therapy (PDT) on dentin with carious lesions in primary teeth.
- Trial name
- NCT02734420
- Testing
- PapacarieMBlue and PDT, Toluidine Blue O and PDT, Laser
- Where
- Brazil
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Pulpitis
Evaluation of Pulpotomy Using Two Different Agents in Mature Anterior Teeth With Pulpitis
the study will evaluate the clinical and radiological success of mature permanent anterior teeth pulpotomy in children and adolescents with signs of pulpitis using two different Biomimetic materials (NeoPutty® and Biodentine™) as…
- Trial name
- NCT06468085
- Testing
- premixed Bioceramic NeoPUTTY®, Biodentine™, Root canal treatment
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Necrotic Pulp
Efficacy of Guedes-Pinto Paste and CTZ Paste in the Non-instrumental Endodontic Treatment of Primary Teeth
The maintenance of the deciduous tooth until its physiological exfoliation occurs is one of the main objectives of pediatric dentistry.
- Trial name
- NCT04587089
- Testing
- Irrigation, Filling with Guedes-Pinto Paste, Filling with CTZ Paste
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Residual Bone Height, Marginal Bone Loss
Influence of Residual Bone Height on Marginal Bone Loss Around Implants Following Lateral Sinus Floor Augmentation With Deproteinized Bovine Bone Mineral
Data collection will be done on all patients who underwent a lateral maxillary sinus floor augmentation in the Faculty of Dental Medicine, both in the Periodontology Department and in the Oral Surgery Department.
- Conditions
- Residual Bone Height, Marginal Bone Loss, Implant Type, Smoking
- Trial name
- NCT07550491
- Testing
- sinus lift using DBBM
- Where
- Lebanon
- Volunteers
- 142 people
- Sponsor
- Saint-Joseph University
Fluorosis, Dental, Enamel Discoloration
The Effectiveness of Antivet Versus Opalustre® for the Management of Enamel Fluorosis/Discolored Enamel and Its Impact on Aesthetic Outcomes.
Dental fluorosis is a developmental enamel defect characterized by discoloration and altered enamel appearance, which may negatively affect dental esthetics and patient satisfaction.
- Trial name
- NCT07707349
- Testing
- Antivet, Opalusture
- Where
- Egypt
- Volunteers
- 59 people
- Sponsor
- October University for Modern Sciences and Arts
Irreversible Pulpitis, Endodontic Inflammation
A Clinical and Radiographic Evaluation of Low-Level Diode Laser Full Pulpotomy in Vital Permanent Teeth
In this study, patients with symptoms of irreversible pulpitis in mature permanent molars were treated with two pulpotomies techniques after random allocation in either 2 groups: Diode laser pulpotomy and traditional pulpotomy…
- Trial name
- NCT06176378
- Testing
- traditional pulpotomy, diode laser pulpotomy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Plaque
Efficacy of Three Experimental Toothpastes to Remove Plaque
The Dose response of three experimental toothpastes (test product 1, test product 2 and test product 3) to remove plaque after a single brushing, compared to a positive control and negative control dentifrice will be evaluated.
- Trial name
- NCT02992691
- Testing
- 20% w/w sodium bicarbonate, 35% w/w sodium bicarbonate, 50% w/w sodium bicarbonate
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Peri-implant Mucositis, Peri-Implantitis
Distance Between Dental Implants as a Risk Indicator for Peri-implant Disease.
The aim of this study is to analyse contiguous dental implants and its peri-implant status depending on different inter-implant distances.
- Trial name
- NCT06364982
- Testing
- Two contiguous dental implants placed with less ≤ 3mm from each other., Two contiguous dental implants placed with > 3mm from each other.
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Tooth Loss
Influence of Soft Tissue Thickness on the Bone Level Around Implants
Healthy soft tissue around the implant are considered as a biological seal to prevent inflammatory periimplant diseases and ensure healthy, stable and long-term survival of a dental implant.
- Trial name
- NCT04243460
- Testing
- Xenogeneic collagen matrix (XCM) graft augmentation, Connective tissue graft augmentation (CTG)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Medical Innovation Center Wroclaw
Dental Plaque, Gingivitis
Essential Oil+ELA, Plaque and Gingivitis
A commercially available mouth rinse with ethyl lauroyl arginate and essential oils claims to have enhanced antimicrobial properties as compared to the traditional essential oil products.
- Trial name
- NCT02884817
- Testing
- Experimental: essential oils and ELA, Water
- Where
- Norway
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Pulp Disease, Dental
Potassium Nitrate in Polycarboxylate as a Direct Pulp Capping
The study aimed to compare potassium nitrate in polycarboxylate cement to mineral trioxide aggregate as a direct pulp capping material of young permanent teeth in patients from 7 to 10 ears
- Trial name
- NCT05912907
- Testing
- potassium nitrate in polycarboxilate cement
- Where
- Egypt
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Minia University
Gingivitis
Evaluation of Air Polishing With Ultrasonic Debridement in the Treatment of Initial Periodontal Pockets
Clinical evaluation of using erythritol powder as air polishing with ultrasonic scaling and root planing in the treatment of initial periodontal pockets.
- Trial name
- NCT03863093
- Testing
- Electro Medical Systems AIRFLOW®, Electro Medical Systems Piezo
- Where
- Syria
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Syrian Private University
Pulp Necrosis, Regeneration
Regeneration of Pulp-Dentin Development in Teeth With Necrotic Pulps and Immature Roots
This multi-center exploratory clinical trial is a randomized trial designed to test whether a regenerative endodontic procedure using tissue engineering principles (REGENDO), or a revascularization (REVASC) endodontic procedure…
- Trial name
- NCT01976065
- Testing
- Triple Antibiotic Paste, Standard Treatment
- Where
- 4 sites in United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Kenneth Hargreaves
Dental Implant Surgical Techniques, Diabetes Mellitus
Effect of Diabetes on Short İmplants in One- and Two-Stage Surgeries
The goal of this clinical trial is to compare one- and two-stage techniques for short implant surgery in diabetes. The main questions it aims to answer are: Is one-stage short implant surgery at risk of implant osseointegration…
- Conditions
- Dental Implant Surgical Techniques, Diabetes Mellitus, Short Dental Implants
- Trial name
- NCT06243276
- Testing
- One stage implant surgery, Two stage implant surgery
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Erzincan University
Gum Disease, Diabetes
Effectiveness of Personalized Oral Hygiene Advice Delivered by Artificial Intelligence or Dental Professionals Versus Standard Oral Hygiene Advice on Oral and Systemic Health in Community-based Type II Diabetes Patients
Diabetes is a systemic condition characterized by elevated blood glucose levels and is associated with multiple long-term complications.
- Trial name
- NCT07841717
- Testing
- AI OHI group, Human-OHI group, Control group
- Volunteers
- 105 people
- Sponsor
- The University of Hong Kong
Root Canal Infection, Bisphosphonate-Associated Osteonecrosis
Root Canal Treatment Outcome in Patients Under Bisphosphonate Therapy
The aim of this study was to evaluate the survival rate and healing time of compromised teeth and seriously compromised teeth that were endodontically treated in patients which received bisphosphonate therapy .
- Conditions
- Root Canal Infection, Bisphosphonate-Associated Osteonecrosis, Periapical Abscess, Endodontically Treated Teeth
- Trial name
- NCT04399720
- Testing
- Root canal treatment
- Volunteers
- 111 people
- Sponsor
- University of Bologna
Dental Plaque, Calculus, Dental
Electric Toothbrush Efficacy in Preventing Dental Plaque Development
The present study will be the first to compared dental plaque quantitation between an oscillating-rotating electric toothbrush and a manual toothbrush with a new QLF technology.
- Trial name
- E-TOOTH (NCT06358482)
- Testing
- oscillating toothbrush, standard manual toothbrush
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Riccardo Polosa
Dental Caries on Pit and Fissure Surface
A Clinical Trial Comparing Isolite® vs. Cotton Roll Isolation in the Placement of Dental Sealants
The purpose of this split-mouth, randomized, controlled trial is to evaluate the retention rates of sealants placed under Isolite vs. cotton roll isolation.
- Trial name
- NCT02668874
- Testing
- Isolite System, Cotton Roll Technique
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Edentulous Alveolar Ridge
Narrow Dental Implants in Multiple Fixed Prosthesis: A Controlled Clinical Trial
The objective of this study is to evaluate the survival of narrow dental implants (≤ 3,5 mm) in multiple fixed prostheses in comparison with standard diameter dental implants (≥ 3,75 mm) after 5 years of follow-up.
- Trial name
- NCT04006782
- Testing
- Narrow dental implants
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Fundación Eduardo Anitua
Dental Caries, Endodontically Treated Teeth
Clinical Evaluation of Posterior Indirect Adhesive Restorations
Clinical performance of indirect adhesive restorations - onlays, overlays- luted with light-cured composite resin will be evaluated over three years.
- Conditions
- Dental Caries, Endodontically Treated Teeth, Dental Restoration Failure of Marginal Integrity, Wear, Occlusal
- Trial name
- NCT04293770
- Testing
- Indirect adhesive restoration of posterior teeth
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Okan University