Clinical trials: Dental Extraction
Tooth Extraction, Alveolar Bone Loss
Autogenous Dentin Graft for Alveolar Ridge Preservatio
When a tooth is extracted, the bone around the empty socket naturally shrinks over time, which can make it difficult to place a dental implant later without additional bone-building procedures.
- Trial name
- ARF-PRF (NCT07789262)
- Testing
- Autogenous Dentin Graft, Platelet-Rich Fibrin (PRF), Freeze-Dried Bone Allograft (FDBA)
- Where
- Turkey (Türkiye)
- Volunteers
- 9 people
- Sponsor
- Ankara Yildirim Beyazıt University
Tooth Extraction
Safety, Tolerability and Efficacy Study of TT-173 in Healthy Volunteers After Tooth Extraction
The purpose of this study is to evaluate the safety, tolerability and efficacy of TT-173 in healthy volunteers after tooth extraction.
- Trial name
- NCT01595360
- Testing
- TT-173
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Thrombotargets Europe S.L
Tooth Extraction Site Healing
Efficacy of Albumin Platelet Rich Fibrin on Complications After Mandibular Third Molar Extraction.
Sixteen patients with bilateral impacted lower third molars seeking treatment will be recruited from the out-patient clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry at Mansoura University.
- Trial name
- NCT07153133
- Testing
- Alb-PRF Autologous Albumin Gel, Surgical extraction of impacted third molar
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Mansoura University
Oral Hygiene
Clinical Study to Investigate the Tooth Stain Removal Efficacy of Two Experimental Toothpastes Compared to a Standard Toothpaste When Used Twice Daily for 8 Weeks
The aim of this study is to investigate the stain removal efficacy of 2 experimental anti-dentin hypersensitivity (DH) dentifrices with four and eight weeks twice daily use.
- Trial name
- NCT05459558
- Testing
- Experimental Dentifrice 1, Experimental Dentifrice 2, Reference Dentifrice
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- HALEON
Endodontic Disease
Effect of Three Mechanical Systems on Removal of Endotoxins From Necrotic Teeth
The patients will be randomly assigned into two equal groups Group : OneShape Group: ProtaperNext Endodontics procedure steps: Patient will be anesthetized by using infiltration local anesthesia or nerve block according to the…
- Trial name
- RCT2019 (NCT04200638)
- Testing
- ProTaper Next
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Alveolar Ridge Preservation, Dental Implants
Ridge Preservation With Moldable Beta-tricalcium Phosphate Bone Substitute on Non-containable Non-Molar Extraction Sites
Purpose of the single arm study is to clinically and histologically evaluate alloplastic in-situ hardening, moldable beta-tricalcium phosphate(TCP) bone graft material and polylactide membrane in alveolar ridge preservation…
- Trial name
- NCT03215667
- Testing
- easy-graft CLASSIC (beta-Tricalcium Phosphate)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Sunstar Americas
Dental Extraction
Human Placenta Extract Use in Socket Preservation
This split-mouth pilot study evaluates the effectiveness of flowable decellularized Human Placental Connective Tissue Matrix (HPCTM) in alveolar ridge preservation following tooth extraction.
- Trial name
- NCT06915675
- Testing
- Placental Extract, Allograft
- Where
- Lebanon
- Volunteers
- 10 people
- Sponsor
- Saint-Joseph University
Missing Tooth, Osseointegration Failure of Dental Implant
X-space Implants in Post-extraction Sites.
Several recent systematic reviews have highlighted how the macrodesign of dental implants can influence stress distribution and biomechanical and biological behavior in implants immediately inserted in post-extraction sites.
- Trial name
- NCT04492111
- Testing
- post-extraction dental implant
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Bari
Dental Implants, Alveolar Ridge Preservation
Assessment of Ridge Preservation Using Moldable Beta-tricalcium Phosphate Bone Grafting System
Randomized Controlled study to compare the effectiveness of two different treatment approaches using a new moldable beta-tricalcium phosphate(TCP) bone graft material in ridge preservation of an atraumatic extraction socket site…
- Trial name
- NCT02702609
- Testing
- easy-graft CLASSIC, FDBA with collagen plug
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- Sunstar Americas
Gingival and Periodontal Disease, Caries, Dental
Clinical Evaluation of the Antibacterial Activity of Thioglycosides Extracted from White Mustard - Bamberka in Oral Hygiene. Evaluation of Periodontal Parameters and Oral Microbiota in Patients.
Brief Summary The goal of this randomized clinical trial is to evaluate the clinical and antibacterial effects of a herbal toothpaste containing white mustard (Sinapis alba) extract in patients diagnosed with gingivitis.
- Trial name
- NCT06908265
- Testing
- Toothpaste including mustard extract
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Periodontitis Complex
Periodontal Regeneration Versus Tooth Extraction and Replacement Denture in Teeth With Periodontal Hopeless Prognosis
Periodontal regeneration can change tooth prognosis and represents an alternative to extraction in teeth compromised by severe intrabony defects.
- Trial name
- NCT04227964
- Testing
- Enamel matrix derivative, bone replacement graft, barrier membrane, Tooth extraction and replacement
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The European Research Group on Periodontology (ERGOPerio)
Endodontic Disease
Effect of Different Root Canal Instruments on Removal of Endotoxins From Necrotic Root Canals
Grouping: The patients will be randomly assigned into two equal groups Group : OneShape Group: ProtaperNext Endodontics procedure steps: 1.
- Trial name
- NCT03641612
- Testing
- one shape, protaper next
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Heba Elasfouri
Alveolar Ridge Preservation Post-Extraction Bone Healing Dental Implant Site Development Tooth Loss
Early Dental Implant Installation in Regeneration Sites: a Prof of Concept Prospective Case Study
This study will evaluate bone healing after tooth extraction and alveolar ridge preservation, a common procedure used to maintain the bone volume needed for future dental implant placement.
- Trial name
- NCT07766057
- Testing
- Alveolar Ridge preservation and early implant placement
- Where
- Chile
- Volunteers
- 10 people
- Sponsor
- Franco Cavalla
Dental Caries
The Study Aims to Compare the Effectiveness of Mesoporous Bioactive Glass-containing Adhesives vs Conventional Universal Adhesives on the Clinical Performance Composite Restorations Through Promoting Dentin Remineralization After Selective Caries Removal Over a Two-year Follow-up
a two-year, double-blind, randomized controlled trial evaluates the effectiveness of a bioactive glass adhesive (Hi-Bond Universal) versus a conventional adhesive (OptiBond Universal) in Class II carious lesions.
- Trial name
- NCT06990945
- Testing
- Hi-Bond Universal Adhesive, OptiBond Universal Adhesive
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Alveolar Bone Grafting, Bone Regeneration Following Wisdom Teeth Extraction
Autogenous Tooth Bone Graft for Alveolar Socket Preservation
The purpose of this clinical experiment is to assess how well autogenous tooth bone grafting preserves the alveolar socket after surgical tooth extraction.
- Conditions
- Alveolar Bone Grafting, Bone Regeneration Following Wisdom Teeth Extraction, Tooth Extraction Site Healing
- Trial name
- ATBG (NCT07267637)
- Testing
- "Autogenous Tooth Bone Graft"
- Where
- Yemen
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Haifaa Mohammed Al-hussini
Deep Caries Lesion of Pemanent Teeth
Outcome of Selective Caries Removal Performed by Undergraduate Students
Deep tooth decay can sometimes reach very close to the nerve of a tooth. Traditionally, dentists may remove all of the decayed tooth tissue, but removing too much tissue can increase the risk of exposing or damaging the nerve.
- Trial name
- NCT07765810
- Testing
- Selective caries removal to soft dentine, Selective Caries Removal to Firm/Leathery Dentine
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Impacted Third Molar Tooth
Clinical Efficacy of a New Piezoelectric Technique for Wisdom Teeth Extraction
the aim of this randomized controlled clinical study is to evaluate the efficacy of a new piezoelectric technique for wisdom teeth extraction without using manual tools versus the conventional one.Patients referred to the…
- Trial name
- NCT03619460
- Testing
- piezoelectric extraction, conventional extraction
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera di Bolzano
Dental Caries, Primary Teeth
Carie Care, Chemomechanical Caries Removal Technique in Primary Teeth
Chemomechanical caries removal systems have emerged as a possible valuable alternative to conventional rotary caries removal techniques in pediatric patients.
- Trial name
- NCT05538559
- Testing
- Chemomechanical caries removal by Carie-Care, Mechanical caries removal by Atraumatic Restorative Technique
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Hams Hamed Abdelrahman
Tooth Impaction, Tooth Diseases
Effects of Chlorhexidine Toothpaste on Wound Healing After Impacted Tooth Extraction
In this study, the postoperative clinical and microbiologic effects of chlorhexidine toothpaste and chlorhexidine-free toothpaste with the same content were compared after bilateral mandibular impacted third molar surgery.
- Trial name
- NCT06067542
- Testing
- Surgery of impacted mandibular wisdom teeth
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Tooth Extraction Status Nos, Bone Augmentation
Using Of Chitosan in Alveolar Ridge Preservation
The goal of this clinical trial is to assess the efficacy of chitosan as a socket preservation material after tooth extraction in compare to the standard treatment.
- Trial name
- NCT06140277
- Testing
- extraction with chitosan particles as a replacement for bone graft with collagen membrane, extraction with placing of allograft particles with collagen membrane, tooth extraction only
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Prince Sattam Bin Abdulaziz University