Clinical trials: Dental Impaction, active
Postoperative Pain, Facial Swelling
Aescin-Based Herbal Extract (Reparil) for Postoperative Sequelae After Mandibular Third Molar Surgery
This randomized, single-blind, controlled clinical trial aims to evaluate the efficacy and safety of Aescin-based herbal extract (Reparil®) compared with Ibuprofen in managing postoperative sequelae following surgical removal of…
- Conditions
- Postoperative Pain, Facial Swelling, Trismus
- Trial name
- Reparil (NCT07244029)
- Testing
- Escin, Ibuprofen 400 mg
- Where
- Oman
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oman Medical Speciality Board
Impacted Fetal Head, Full Dilatation Caesarean Section
Lifting the Impacted Fetal Head; the Fetal Pillow and Tydeman Tube Trial
A single centre prospective observational comparison trial to compare the Tydeman Tube and Fetal Pillow, to aid delivery of the impacted fetal head at full dilatation caesarean section, and to evaluate the use of the Tydeman Tube…
- Trial name
- LIFT (NCT07372768)
- Testing
- Fetal Pillow, Tydeman Tube
- Volunteers
- 80 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Wound Heal, Surgical Wound
Chlorhexidine Plus Hyaluronic Acid Mouthwash in Surgical Wound Healing Following Third Molar Surgery
Evaluation of the response of gingival tissues to the use of mouthwash with chlorhexidine and chlorhexidine + hyaluronic acid in terms of healing of the surgical wound following third molar surgery.
- Conditions
- Wound Heal, Surgical Wound, Impacted Third Molar Tooth
- Trial name
- CLOR_4 (NCT05414253)
- Testing
- Parallel Assignment
- Where
- Italy
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Pisa
TMJ, Apical Periodontitis
Application of a Dental-dedicated MRI in the Diagnosis of Temporomandibular Joint Disorders, Tissue Alterations Related to Third Molars, Periapical and Periodontal Inflammatory Diseases, and Implant Treatment Planning
The aim of the present study is to show that the use of 0.55T MRI combined with a "dental" coil produces images of sufficient diagnostic value to assess areas of interest in dentistry, and to compare MR images to traditional…
- Conditions
- TMJ, Apical Periodontitis, Periodontal Inflammation, Retained Tooth
- Trial name
- NCT05439330
- Testing
- MRI of teeth and surrounding structures
- Where
- Denmark
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Opioid-Related Disorders, Substance-Related Disorders
Pre-Pilot (R61) WINGS+++: mHealth to Improve MOUD Uptake in Women Experiencing Intimate Partner Violence and PTSD
The goal of this pre-pilot for the clinical trial is to develop a mobile health (mHealth) program called WINGS+++ can help women with opioid use disorder or other substance use disorders who have experienced intimate partner…
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders, Intimate Partner Violence (IPV), Stress Disorders, Post-Traumatic
- Trial name
- NCT07665502
- Testing
- Pre-Pilot WINGS++++
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- Dawn A. Goddard-Eckrich
Oral Health
Effect of Hypochlorous Acid-containing Mouthwash on Healing After Impacted Wisdom Tooth Surgery
INTRODUCTION: Local chemotherapeutic agents are used to reduce inflammation after impacted tooth extraction and to minimize possible complications, as well as to increase patient comfort.
- Trial name
- Mouthwash (NCT06920485)
- Testing
- Third molar surgery, Pain Medicine, Wound healing
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Third Molar Impaction, Surgical Extraction of Impacted Third Molars
The Effect of Platelet Rich Fibrin On Sensitivity and Periodontal Pockets Distal to Second Molar After Surgical Extraction of Impacted Third Molar
Surgical extraction of impacted third molar is the most common surgical procedure performed in oral and maxillofacial surgery. The immediate post operative complications after 3rd molar surgery are pain, swelling and trismus…
- Trial name
- NCT07351279
- Testing
- Platelet rich fibrin
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- University of Health Sciences Lahore
Type II Diabetes Mellitus
Study to Evaluate if Exposure to Drug is Impacted in Participants With Renal Insufficiency
This is an open-label, single-dose, Phase 1 clinical study designed to evaluate the effect of renal impairment on the pharmacokinetics (PK) of GL0034, a long-acting GLP-1 receptor agonist.
- Trial name
- NCT07385547
- Testing
- GL0034
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries Limited
Impacted Third Molar Tooth
Lidocaine Patch and Lower Third Molar
Completed medical and dental history will take for all patients and the position of the impacted teeth will evaluate by panoramic films.
- Trial name
- NCT07330726
- Testing
- Lidocaine patch
- Volunteers
- 21 people
- Sponsor
- Fayoum University
Alveolar Bone Loss
Demineralized Dentin Allograft Versus Demineralized Dentin Autograft for Socket Preservation
This study is designed to evaluate and compare clinically and radiographically the effectiveness of Demineralized Dentin Allograft (DDA) versus Demineralized Dentin Autograft (Auto-DD) for preservation of alveolar ridge…
- Trial name
- NCT06457373
- Testing
- Demineralized Dentin Allograft, Demineralized Dentin Autograft
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Horus University
Survivorship, Prostate Cancer
Linking In With Advice and Supports for Men Impacted by Metastatic Cancer
To evaluate the feasibility of introducing a men's cancer survivorship programme into routine follow up care in patients with advanced genitourinary malignancies.
- Conditions
- Survivorship, Prostate Cancer, Kidney Cancer, Urothelial Tract/Bladder Cancer, Nos
- Trial name
- LIAM Mc (NCT05946993)
- Testing
- Physiotherapy, Dietitian Support, Nursing and Psychosocial
- Where
- Ireland
- Volunteers
- 72 people
- Sponsor
- University College Cork
Deep Sedation, Non-invasive Ventilation Support
Comparison of Nasal Continuous Positive Airway Pressure (CPAP) Mask and Nasal Airway in Molar Tooth Extraction Under Deep Sedation
In patients with high levels of fear and anxiety, it is recommended to perform dental procedures under sedation or general anesthesia depending on the nature of the procedure.
- Conditions
- Deep Sedation, Non-invasive Ventilation Support, Nasal Airway, Nasal CPAP Mask
- Trial name
- NCT06436638
- Testing
- Non-invasive ventilation support equipment
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gözde Nur Erkan
Environmental Exposure
Assessing and Addressing Community Exposures to Environmental Contaminants
The purpose of this study is to build on our equitable, eight-year Tribal-academic partnership with the Ramapough Nation of northern NJ to advance tradition-centered farming practices and management strategies supporting…
- Trial name
- NCT06315140
- Testing
- Nutrition
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Oral Health Care
The Effect of Supplementary Foods Containing Trypsin, Chymotrypsin and Serratia Peptidase on Healing After Impacted Wisdom Tooth Surgery
Introduction: The aim of this study was to determine the effects of a dietary supplement containing trypsin, chymotrypsin, and serratia peptidase (Tripser Forte N30, Incir Pharma, Turkey) on postoperative healing and to determine…
- Trial name
- Trypsin (NCT07269171)
- Testing
- Pain Assessment, Number of Analgesics Needed, Edema Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Swelling/ Edema, Trismus
The Effect of Dexamethasone Submucosal Injection After Surgical Extraction of Lower Impacted Third Molars on Trismus and Edema
This clinical trial aims to investigate whether dexamethasone decreases edema and trismus in adults undergoing lower third molar surgical extraction.
- Trial name
- NCT06953440
- Testing
- Dexamethasone Sodium Phosphate Injection
- Where
- Saudi Arabia
- Volunteers
- 66 people
- Sponsor
- King Abdulaziz University
Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar
Comparison of PRF and Corticosteroids in Impacted Third Molar Surgery
This prospective, randomized interventional study aims to compare the postoperative effects of standard treatment (control), platelet-rich fibrin (PRF), and PRF combined with corticosteroid treatment in patients undergoing…
- Conditions
- Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar, Impacted Wisdom Tooth
- Trial name
- NCT07742826
- Testing
- Platelet-rich fibrin (PRF), Dexamethasone, Amoxicillin/Clavulanic Acid
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Final International University
Postoperative Pain, Postoperative Complications
Evaluation of the Effect of Tea Tree and Chlorhexidine Mouthwashes on Healing After Third Molar Extraction
The purpose of this clinical study is to compare the effects of mouthwashes containing Chlorhexidine and tea tree oil on edema, pain, and trismus after the extraction of impacted third molars.
- Conditions
- Postoperative Pain, Postoperative Complications, Trismus, Periodontal Health
- Trial name
- NCT07180498
- Testing
- Chlorhexidine Gluconate 0.12% Mouthwash, Tea Tree Oil mouthwash
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Harran University
Mandibular Diseases, Guided Surgery
Computer Guided Split Thickness Versus Full Thickness Flap Buccal Bone Lid Approach in Hard Mandibular Pathosis
Full thickness Buccal bone lid approach is well known and well reported technique with a superiority on preserving bone volume and better bone healing especially when done using piezoelectrical devices when compared to…
- Conditions
- Mandibular Diseases, Guided Surgery, Guided Surgery Accuracy
- Trial name
- NCT07338136
- Testing
- computer guided split thickness flap for buccal bone lid approuch
- Volunteers
- 26 people
- Sponsor
- Cairo University
Impacted Tooth
Application of Surgical Templates in the Surgical Exposure of Impacted Canines
The first choice therapy in case of palatally impacted canines is their exposure and orthodontic eruption to improve facial esthetics and prevent pathologies associated with impacted teeth and Temporomandibular Joint Disorders.
- Trial name
- NCT05909254
- Testing
- Palatally impacted canine exposure using a surgical guide, Palatally impacted canine exposure using the conventional free.hand method
- Where
- Hungary
- Volunteers
- 40 people
- Sponsor
- Semmelweis University
Impacted Mandibular Third Molar, Postoperative Morbidity
The Effect of Different Flap Closure Techniques on Postoperative Morbidity in Impacted Third Molar Surgery
1. ABSTRACT This study is a randomized controlled trial comparing the clinical efficacy and safety of four different flap closure techniques in reducing postoperative morbidity (pain, swelling, trismus, wound healing) and…
- Conditions
- Impacted Mandibular Third Molar, Postoperative Morbidity, Oral Surgery
- Trial name
- GMC02 (NCT07198282)
- Testing
- Conventional Suturing, Sutureless Technique, Surgical Drain
- Where
- Turkey (Türkiye)
- Volunteers
- 148 people
- Sponsor
- Recep Tayyip Erdogan University