Clinical trials: Dental Occlusion
Atrial Fibrillation
Left Atrial Appendage Occlusion With The Amplatzer Amulet Device: The Southeast Asia Observational Study
This is a prospective and retrospective, multicenter observational study where the study is being performed to explore on the short-term and long-term safety and efficacy of LAA occlusion with Amplatzer Amulet Device in Southeast…
- Trial name
- NCT05687591
- Testing
- Amplatzer Amulet Left Atrial Appendage Occlusion Device
- Where
- Malaysia
- Volunteers
- 104 people
- Sponsor
- Sarawak Heart Centre
Bone Loss, Occlusion
Comparative Clinical and Radiographical Evaluation of Treatment of Angular Bone Defect Related to Over Erupted Tooth Using GTR Followed by Orthodontic Intrusion Versus Orthodontic Intrusion Followed by GTR
Occlusal prematurity leading to loss of vertical stopping points between teeth can lead to teeth over eruption creating abnormal contact area which favors food accumulation and plaque retention.
- Trial name
- NCT05371418
- Testing
- surgical (guided tissue regeneration), orthodontic intrusion followed by guided tissue regeneration GTR
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Tanta University
Occlusion
Effects of Clear Aligners Versus Fixed Appliances on Occlusion After Treatment of Mild Anterior Crowding
The aim of this study is to evaluate effects of clear aligners versus fixed appliances on occlusion after treatment of mild anterior crowding a T-scan study.
- Trial name
- NCT05737290
- Testing
- Clear aligners, Fixed appliances
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Chronic Total Occlusion
A Single Center Study to Evaluate the Safety of the NovaCross Microcatheter in Crossing Chronic Total Occlusions
This is an open label, single-center, prospective, pivotal study in which the investigational device, NovaCross™ micro-catheter, will be tested in up to 15 patients scheduled to undergo CTO-PCI using an anterograde approach.
- Trial name
- NCT04862559
- Testing
- NovaCross
- Where
- Poland
- Volunteers
- 15 people
- Sponsor
- Nitiloop Ltd.
Atherosclerosis, Peripheral Arterial Disease
Stella Supera Siberia
Endovascular treatment with stenting is currently used in the treatment of femoro-popliteal lesions. This technique tends to extend to lesions for which the gold standard remains until now the open surgery treatment (lesions TASC…
- Conditions
- Atherosclerosis, Peripheral Arterial Disease, Superficial Femoral Artery Occlusion
- Trial name
- NCT03951727
- Testing
- Endovascular treatment for PAD
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Myocardial Injury After Noncardiac Surgery (MINS), Postoperative Complications
Prediction Model for MINS After Major Hepatobiliary Surgery
This multi-center, prospective observational study aims to develop and validate an interpretable prediction model for Myocardial Injury After Noncardiac Surgery (MINS) in patients undergoing major hepatobiliary surgery.
- Conditions
- Myocardial Injury After Noncardiac Surgery (MINS), Postoperative Complications, Liver Neoplasm, Hepatobiliary Diseases
- Trial name
- NCT07335042
- Testing
- Major Hepatobiliary Surgery
- Where
- 6 sites in China
- Volunteers
- 1,800 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Ischemic Optic Neuropathy, Branch Retinal Artery Occlusion
New Non-invasive Modalities for Assessing Retinal Structure and Function
This study investigates a new technology to assess the structure and function inside the eye. Retinal imaging of subjects with inner and outer retinal defects to detect areas of abnormal structure and function compared to other…
- Conditions
- Ischemic Optic Neuropathy, Branch Retinal Artery Occlusion, Hemianopia, Leber Hereditary Optic Neuropathy
- Trial name
- NCT03475173
- Testing
- LSFG-NAVI
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Randy Kardon
Cardiopulmonary Arrest
REBOA in Nontraumatic OHCA
The investigators propose a multicenter randomized controlled trial in South Korea and Taiwan to observe the clinical effects of REBOA on nontraumatic out-of-hospital-cardiac-arrest (OHCA) patients.
- Trial name
- REBOA (NCT06031623)
- Testing
- REBOA
- Where
- South Korea
- Volunteers
- 234 people
- Sponsor
- Seoul National University Hospital
Chronic Total Occlusions of Coronary Arteries, Stress Echocardiography (SE)
Predicting Functional Recovery After Coronary Chronic Total Occlusion Revascularization
Chronic total occlusion (CTO) is defined as complete coronary occlusion with TIMI flow grade 0 persisting for more than three months, identified in 15-25% of patients undergoing coronary angiography.¹,² CTO is associated with…
- Conditions
- Chronic Total Occlusions of Coronary Arteries, Stress Echocardiography (SE), Inflammation Biomarkers
- Trial name
- StressECHOCTO (NCT07879573)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Childhood Cancer, Central Venous Catheters
Identification and Treatment of Clinically Silent Catheter-Related Deep Vein Thrombosis in Children With Cancer
The primary hypothesis of this study is that occult catheter-related DVT in children with cancer is common and directly contributes to development of serious catheter complications, specifically bacteremia/fungemia and/or…
- Conditions
- Childhood Cancer, Central Venous Catheters, Deep Vein Thrombosis, Catheter-related Infection
- Trial name
- DVT (NCT00633061)
- Testing
- Enoxaparin
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- University of Texas Southwestern Medical Center
Amblyopia
Electronic Recording of Compliance With Occlusion Therapy for Amblyopia
The purpose of this study was to determine whether compliance with occlusion therapy for amblyopia could be improved and, secondly, if risk factors for non-compliance could be identified.
- Trial name
- NCT00131729
- Testing
- Educational programme
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 200 people
- Sponsor
- Erasmus Medical Center
Peripheral Artery Disease, Femoropoliteal Stenosis/Occlusion
Registry of Cutting Balloon and DCB Intervention in Femoropopliteal Stenosis/Occlusion.
Observational registry including patients with peripheral artery disease due to femoro-popliteal stenosis or occlusion treated with cutting ballon- and subsequent drug-coated-ballon-percutaneous-transluminal-angioplasty (PTA).
- Conditions
- Peripheral Artery Disease, Femoropoliteal Stenosis/Occlusion, Cutting-balloon, Drug-coated-balloon
- Trial name
- DEBTRAK (NCT02198105)
- Testing
- Cutting-Balloon-PTA (VascuTrak) and Drug Coated Ballon PTA
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Caritasklinik St. Theresia
Branch Retinal Vein Occlusion
Proof of Concept Study of Re-treatment in BRVO With Ranibizumab Guided by OCT
The aim of the trial is to evaluate the efficacy and safety of intravitreal injections of ranibizumab for the treatment of macular edema due to BRVO if the re-treatment regimen is guided by morphological macular changes detected…
- Trial name
- RabOCT (NCT01968239)
- Testing
- Ranibizumab
- Where
- Germany
- Volunteers
- 27 people
- Sponsor
- University of Leipzig
Coronary Artery Ischemia
Remote Myocardial Ischemic Preconditioning in Humans
Ischemic preconditioning (IP) has been shown in animal studies to increase the myocardial tolerance to subsequent ischemia. Our primary hypothesis is that remote IP reduces myocardial ischemic injury during PCI.
- Trial name
- RemoteMIPH (NCT00588042)
- Testing
- Blood pressure cuff
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Mayo Clinic
Malocclusion, Dementia
Oral Health for Healthy Cognitive Aging
Oral health is a critical factor of systemic health, although usually forgotten. A potential relation between cognitive deficits and oral diseases has been suggested.
- Trial name
- SOECS (NCT02986386)
- Testing
- Dental occlusion restoration, Orthodontic treatment of malocclusion
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Universidad de Granada
Acute Ischemic Stroke, Intracranial Atherosclerosis ICAS
Effect of Balloon Angioplasty vs Stenting Following Residual Stenosis After Endovascular Treatment of Intracranial Atherosclerotic Acute Ischemic Stroke
The ANGEL-ICAS trial is a multicenter, prospective, randomized, open-label, blinded-endpoint study designed to determine whether rescue balloon angioplasty is noninferior to rescue stenting in patients with intracranial…
- Trial name
- ANGEL-ICAS (NCT07026331)
- Testing
- balloon angioplasty, Stent
- Where
- China
- Volunteers
- 486 people
- Sponsor
- Beijing Anzhen Hospital
Age-Related Macular Degeneration, Retinal Vein Occlusion
Extension Study to Gather Data on Effect of Macugen on the Corneal Endothelium
This study was conducted because the FDA requested clinical information on potential effects of intravitreal injections of Macugen (pegaptanib sodium injection) on the corneal endothelium from a 1-year (minimum) post-approval…
- Conditions
- Age-Related Macular Degeneration, Retinal Vein Occlusion, Diabetic Macular Edema
- Trial name
- NCT01573572
- Testing
- pegaptanib sodium injection
- Where
- 4 sites in United States
- Volunteers
- 131 people
- Sponsor
- Bausch & Lomb Incorporated
Stroke, Acute Ischemic
Early Endovascular Treatment in Isolated Internal Carotid Artery Occlusion
The primary hypothesis being tested in this trial is that acute ischemic stroke with isolated internal carotid artery occlusion will have improved clinical outcomes when given early endovascular treatment compared with that of…
- Trial name
- EVT-iICAO (NCT07016854)
- Testing
- Endovascular treatment, The best medical treatment
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Sir Run Run Shaw Hospital
Femoral Artery Stenosis, Femoral Artery Occlusion
A Single Arm Trial Evaluating the BARD Lutonix Drug-Coated Balloon (LTX DCB) for Treatment of Femoropopliteal Arteries
To assess the safety and efficacy of the BARD LTX DCB for treatment of stenosis or occlusion of the superficial femoral and popliteal arteries.
- Conditions
- Femoral Artery Stenosis, Femoral Artery Occlusion, Stenosis of Popliteal Arteries, Occlusion of Popliteal Arteries
- Trial name
- NCT02720003
- Testing
- LTX DCB
- Where
- 14 sites in China
- Volunteers
- 148 people
- Sponsor
- C. R. Bard
Dental Caries
Effectiveness of the Intraligamentary Anesthesia and Inferior Alveolar Nerve Block on Pain During Dental Treatment
Objective: To compare the effectiveness and complications of intraligamentary anesthesia (ILA) with conventional inferior alveolar nerve block (IANB) during injection and dental treatment of mandibular posterior teeth.
- Trial name
- NCT04563351
- Testing
- local anaesthetic techniques
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
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