Clinical trials: Dental Occlusion
Ophthalmopathy
Injection of Ranibizumab Versus Combination of Ranibizumab and Triamcinolone Acetate for (CRVO)
To compare the clinical effectiveness of ranibizumab and combination of ranibizumab and triamcinolone for the treatment of macular oedema secondary to CRVO
- Trial name
- NCT04460001
- Testing
- Ranibizumab, triamcinolone acetate
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Dry Eye
Partial Lacrimal Punctual Occlusion
The purpose of this study is to describe a case series of patients with chronic dry eye submitted to partial punctual occlusion.
- Trial name
- PLPO (NCT00802399)
- Testing
- Partial Lacrimal Punctual Occlusion
- Where
- Brazil
- Volunteers
- 37 people
- Sponsor
- University of Sao Paulo General Hospital
Infertility
In Vitro Maturation With in Vitro Fertilization (IVF) Compared to Mild in Vitro Fertilization
Methods of infertility treatment may involve in vitro fertilization or IVF. Though effective, IVF is complex and expensive. Methods using no gonadotropin hormone stimulation of the ovaries are being compared to mild stimulation…
- Trial name
- IVM vs IVF (NCT00867763)
- Testing
- In vitro maturation and in vitro fertilization, Low doses of gonadotropin stimulation.
- Where
- 2 sites in United States
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- Batzofin Fertility Services
Chronic Total Occlusion, Atherosclerosis
Registry Study to Evaluate the Performance and Safety of Roxwood Medical Catheters in Arteries of Participants With a Stenotic Lesion or Chronic Total Occlusion (CTO)
The purpose of this registry study is to gather real world standard of care (SOC) data on the safety and performance on the Roxwood Medical catheter devices in the treatment of stenotic lesions and CTO.
- Conditions
- Chronic Total Occlusion, Atherosclerosis, Coronary Artery Disease, Peripheral Artery Disease
- Trial name
- NCT04059536
- Testing
- Roxwood Anchoring Catheters, Acetylsalicylic Acid, Heparin
- Where
- 11 sites in United States
- Sponsor
- Boston Scientific Corporation
Acute Ischemic Stroke, Basilar Artery Occlusion
Efficacy and Safety of Endovascular Recanalization for Acute Basilar Artery Occlusion With Extended Time Window (ANGEL-BAO)
The aim of this study is to assess the efficacy and safety of endovascular treatment versus medical management in patients with acute basilar artery occlusion with extended time window of 24-72 hours from onset.
- Trial name
- ANGEL-BAO (NCT06101667)
- Testing
- Best medical management, Endovascular treatment
- Where
- China
- Volunteers
- 224 people
- Sponsor
- Beijing Tiantan Hospital
Endodontic Disease
Time Efficiency and Obturation Quality of Rotary Versus Manual in Primary Teeth
The aim of this study is to evaluate the quality of obturation and the time efficiency of rotary versus manual instrumentation in roots of deciduous molars clinically where the: Primary objective Is to evaluate the time…
- Trial name
- NCT04102293
- Testing
- NSK Endo motor Endomate, manual K-files
- Where
- Egypt
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Reem Mahmoud Abdelkader Awad
Edentulous Alveolar Ridge In Mandible, Complete Edentulism
Using Two Different Attachments (Equator Vs Ball and Sockets) Retaining Mandibular Implant Overdenture in Order to See Bone Changes and Occlusal Force Distribution
Alveolar ridge resorption is an unavoidable consequence in complete denture wearers due to limited retention and stability. Implant-retained overdentures enhance retention, stability, and masticatory performance while reducing…
- Conditions
- Edentulous Alveolar Ridge In Mandible, Complete Edentulism, Dental Implant, Attachments
- Trial name
- NCT07241481
- Testing
- Ball & Socket Attachment, Equator Attachment
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries
Decision Aids for the Management of Suspicious Occlusal Caries Lesions
The study will determine whether clinicians who use a diagnostic device treat suspicious occlusal carious lesions (SOCL) surgically more often, with the same frequency, or less frequently, than dentists not relying on a…
- Trial name
- SOCL (NCT02340767)
- Testing
- Spectra Device, DIAGNOdent
- Where
- 6 sites in United States
- Volunteers
- 3,085 people, healthy volunteers welcome
- Sponsor
- The National Dental Practice-Based Research Network
Greater Palatine Nerve Block, Inferior Alveolar Nerve Block
Evaluation of Use of Ultrasound for Greater Palatine Nerve Block and Inferior Alveolar Nerve Blocks: An Open Label Feasibility Study
Dental anesthesia is routinely performed based on anatomical landmarks which can be variable leading to repeated injections and failure.
- Trial name
- NCT01870232
- Testing
- US guided block
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
no Obvious Abnormalities, Diabetic Retinopathy (DR)
Retinal Clinical Assessment With AI-derived Quantitative Information
This randomized controlled trial evaluates whether providing clinicians with AI-derived quantitative retinal information improves the quality and efficiency of retinal clinical assessment.
- Conditions
- no Obvious Abnormalities, Diabetic Retinopathy (DR), AMD, Cup-to-disc Ratio Bigger Than 0.5
- Trial name
- NCT07291960
- Testing
- AI-derived retinal quantitative information-assisted reporting
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Retinal Vein Occlusion
Extension Study to Compare Long-term Efficacy and Safety of Ranibizumab Intravitreal Injections Versus Dexamethasone Intravitreal Implant in Patients With RVO
The study is intended to characterize the clinical benefit regarding safety and efficacy of a long term treatment with Lucentis in comparison with Ozurdex over an additional 6 months and a 3-month follow-up period, following the…
- Trial name
- NCT01580020
- Testing
- RFB002, Dexamethasone
- Where
- 37 sites in Germany
- Volunteers
- 175 people
- Sponsor
- Novartis Pharmaceuticals
Atrial Fibrillation New Onset, Embolic Stroke of Undetermined Source
PFO Occlusion and Atrial Fibrillation
Interventional closure of patent foramen ovale (PFO) associates with reduced risk of stroke recurrence in patients with cryptogenic ischemic stroke as reported in the recent CLOSE and REDUCE trials.
- Conditions
- Atrial Fibrillation New Onset, Embolic Stroke of Undetermined Source, Patent Foramen Ovale
- Trial name
- NCT04898361
- Testing
- PFO closure
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University Hospital, Saarland
Retinal Vein Occlusion With Macular Edema
Efficacy and Safety Evaluation of SMO1 in Patients With Retinal Vein Occlusive Macular Edema
This is a multicenter, randomized, double-masked, parallel-group, active-controlled Phase 3 clinical trial designed to evaluate the efficacy and safety of SMO1 (Dexamethasone 700μg intravitreal implant) compared with the…
- Trial name
- NCT07708142
- Testing
- Reference Drug, SMO1
- Where
- South Korea
- Volunteers
- 312 people
- Sponsor
- SANGMYUNG innovation
Knee Osteoarthritis, Knee Pain Chronic
Genicular Artery Embolization (GAE) for Osteoarthritic Knee Pain
The objective of this investigation is to evaluate the safety of the geniculate artery embolization (GAE) procedure with HydroPearl® Microspheres in 30 patients with knee pain caused by osteoarthritis with 24 months follow-up.
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Pain Swelling, Knee Arthritis
- Trial name
- NCT04472091
- Testing
- Genicular artery embolization (GAE)
- Where
- United States
- Sponsor
- Andrew Picel
Common Femoral Artery Occlusive Disease
A Prospective, Multicenter, Observational Study on the Treatment of Chronic Common Femoral Artery Bifurcation Occlusion
This study is a prospective, multicenter real-world observational study to understand the safety and efficacy of endoluminal therapy and traditional endometristomy in the real world for patients with severe stenosis and occlusion…
- Trial name
- EAST-CFA (NCT05603546)
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Qingdao Hiser Medical Group
Coronary Disease, Coronary Artery Disease
PROSPECT: An Imaging Study in Patients With Unstable Atherosclerotic Lesions
PROSPECT is a multi-center prospective registry of Acute Coronary Syndromes (ACS) patients with single or double vessel coronary artery disease.
- Conditions
- Coronary Disease, Coronary Artery Disease, Coronary Restenosis
- Trial name
- NCT00180466
- Where
- 40 sites in United States, Belgium and 10 more
- Volunteers
- 697 people
- Sponsor
- Abbott Medical Devices
Osteoarthritis
Vascular Occlusion in Patients With Osteoarthritis
Resistance exercise plus vascular occlusion may induce greater improvements in strength and muscle mass than resistance training alone.
- Trial name
- NCT01483131
- Testing
- Exercise training, Resistance training with vascular occlusion
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Caries
Occlusal Compensation After the Hall Technique
The Hall Technique preformed metal crown (HTPMC) is used to treat decayed primary molars. The correct size is chosen and pushed over the tooth with no tissue removal.
- Trial name
- CHAT (NCT04001153)
- Testing
- Dental impressions
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Dundee
Dental Caries
Cost-efficacy of Sealing Moderate Caries Lesions in Occlusal Surfaces of Primary Molars
This protocol aims to assess the cost-efficacy and applicability of the treatment of lesions moderate caries using sealants as an alternative to the restorations on occlusal surfaces of deciduous teeth.
- Trial name
- NCT03005405
- Testing
- Ionomer Restoration (control), Ionomer Sealant (test), Oral hygiene orientation and professional fluoride application
- Where
- Brazil
- Volunteers
- 96 people
- Sponsor
- University of Sao Paulo
Chronic Total Occlusion (CTO), Coronary Artery Disease
Turkish Chronic Total Occlusion Percutaneous Coronary Intervention Registry
The TURK CTO Registry is a prospective, multicenter, observational registry designed to evaluate the contemporary management and outcomes of percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) in Türkiye.
- Trial name
- TURK_CTO (NCT07761624)
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 70,000 people
- Sponsor
- Ahmet Seyfeddin Gürbüz
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.