Clinical trials: Dental Occlusion
Dental Pulp Necrosis, Periapical Periodontitis
Measurement of Bite Force in Humans
This protocol is for a clinical trial to evaluate the reliability of the bite fork as a diagnostic instrument in subjects with pulpal necrosis and apical periodontitis.
- Trial name
- NCT00223327
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Ischemic Stroke
Total Posterior-circulation Infarct Volume in Basilar Artery Stroke
Preprocedural predictors of outcome in patients with acute basilar artery occlusion (ABAO) who underwent endovascular treatment (EVT) remain controversial.
- Trial name
- TPCIV-ABAO (NCT04650022)
- Testing
- Mechanical thrombectomy
- Where
- France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Montpellier
Study Vasodilatory Effects of C21
Effect of C21 on Forearm Blood Flow
The purpose of this study is to assess the effect of C21 on forearm blood flow by use of strain-gauge venous occlusion plethysmography.
- Trial name
- NCT05277922
- Testing
- C21, Sodium Nitroprusside
- Where
- Sweden
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Vicore Pharma AB
Chronic Total Occlusion (CTO)
FAPI Imaging Assessment of Chronic Total Occlusion
This registry will include consecutive patients presenting with at least one chronic total coronary occlusion (CTO) identified via coronary angiography or cardiac computed tomography angiography (CCTA) at our center.
- Trial name
- FACT (NCT06655922)
- Testing
- FAPI Imaging
- Where
- 2 sites in China
- Volunteers
- 167 people
- Sponsor
- Lin Zhao
Age-Related Macular Degeneration, Retinal Vein Occlusion
Extension Study to Gather Data on Effect of Macugen on the Corneal Endothelium
This study was conducted because the FDA requested clinical information on potential effects of intravitreal injections of Macugen (pegaptanib sodium injection) on the corneal endothelium from a 1-year (minimum) post-approval…
- Conditions
- Age-Related Macular Degeneration, Retinal Vein Occlusion, Diabetic Macular Edema
- Trial name
- NCT01573572
- Testing
- pegaptanib sodium injection
- Where
- 4 sites in United States
- Volunteers
- 131 people
- Sponsor
- Bausch & Lomb Incorporated
Liver Transplant
Hepato-duodenal Ligament Occlusion and Classic Technique in Liver Transplant
Liver transplantation was historically associated with massive blood loss. Many factors have contributed to the decline in bleeding and transfusion in the past two decades including refinement of surgical techniques, anesthetics…
- Trial name
- NCT04265157
- Testing
- Surgical technique surgical occlusion
- Volunteers
- 50 people
- Sponsor
- Assiut University
Portal Vein Occlusion, Cholangiocarcinoma, Perihilar
Portal Vein Embolization Using Coils Plus TAGM vs Multiple Coils for Patients With Perihilar Cholangiocarcinoma or Hepatocellular Carcinoma
The aim of this study is to investigate the differences of safety and liver hypertrophy between portal vein embolization (PVE) using coils plus tris-acryl gelatin microspheres (TAGM) and multiple coils in patients with perihilar…
- Conditions
- Portal Vein Occlusion, Cholangiocarcinoma, Perihilar, Hepatocellular Carcinoma, Liver; Hypertrophy, Acute
- Trial name
- NCT04386772
- Testing
- PVE with coils plus TAGM, PVE with multiple coils
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Eastern Hepatobiliary Surgery Hospital
Coronary Angiography, Radial Artery Occlusion
The Prevalence of Radial Artery Occlusion in Diagnostic Cardiac Catheterization and Percutaneous Intervention
The purpose of this study is to establish the rate of radial artery occlusion post transradial cardiac catheterization through different modalities.
- Trial name
- NCT01996553
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Jesse Brown VA Medical Center
Chronic Total Occlusion of Coronary Artery
Evaluation of Effectiveness and Safety of Antegrade and Retrograde Approach of Percutaneous Coronary Intervention for Chronic Total Occlusions
Objective of this study is to 1) analyze the clinical, anatomical and periprocedural differences of patients who underwent a procedure related to coronary CTO through the antergrade approach and retrograde approach; 2) analyze…
- Trial name
- STRIKE-CTO (NCT03667196)
- Testing
- antegrade and retrograde approach
- Where
- 32 sites in South Korea
- Volunteers
- 4,000 people
- Sponsor
- Seung-Whan Lee, M.D., Ph.D.
Coronary Disease, Coronary Artery Ectasia
Outcomes After PCI of the Aneurysmatic Right Coronary Artery
This study aims to evaluate procedural and clinical outcomes of acute coronay syndrome (ACS) patients with aneurysmatic culprit right coronary artery (RCA).
- Conditions
- Coronary Disease, Coronary Artery Ectasia, Right Coronary Artery Occlusion, Right Coronary Artery Stenosis
- Trial name
- RIGHT-MARE (NCT05713201)
- Testing
- Percutaneous Coronary Intervention
- Where
- 8 sites in Italy, Spain
- Volunteers
- 90 people
- Sponsor
- San Luigi Gonzaga Hospital
Amblyopia
Electronic Recording of Compliance With Occlusion Therapy for Amblyopia
The purpose of this study was to determine whether compliance with occlusion therapy for amblyopia could be improved and, secondly, if risk factors for non-compliance could be identified.
- Trial name
- NCT00131729
- Testing
- Educational programme
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 200 people
- Sponsor
- Erasmus Medical Center
Retinal Vein Occlusion
Vitreous Level Of Tumor Necrosis Factor Alpha In Patients With Retinal Vein Occlusion
To assess the levels of TNF- α in vitreous samples of patients with retinal vein occlusion prior to administration of intravitreal anti-VEGF and compare them to levels in vitreous samples of normal subjects so as to investigate…
- Trial name
- NCT05532475
- Testing
- measurement of vitreous level of tumor necrosis factor alpha
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kasr El Aini Hospital
Stroke, Ischemic, Large Vessel Occlusion
Biomarkers algOrithm for strOke diagnoSis and Treatment Resistance Prediction
Triage of acute ischemic stroke (AIS) patients is critical, to decrease time to treatment, and improve functional outcome. The therapeutic standard of care for AIS consecutive to large vessel occlusion (LVO) is the association of…
- Trial name
- BOOST (NCT04726839)
- Testing
- Standard of care for stroke management and evaluation of functionnal outcome at 3 months
- Where
- 4 sites in France
- Volunteers
- 3,880 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke, Acute Ischemic Stroke
The MRI-based Evaluation of Safety and Efficacy of EVT and SMT: A Retrospective, Multicenter Study
Acute Basilar Artery Occlusion (ABAO), a condition with a high risk of mortality or disability (up to 80%). The safety and efficacy of endovascular thrombectomy (EVT) in ABAO remains uncertain due to inconsistent evidence from…
- Conditions
- Stroke, Acute Ischemic Stroke, Ischemic Stroke
- Trial name
- NCT06236828
- Testing
- Mechanical Thrombectomy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Retinal Vasculitis
Incidence of Retinal Vasculitis Among Patients Receiving Aflibercept: A US Real-World Evidence Study
This study will describe and estimate the incidence of Retinal Vasculitis (RV) events among patients and patient eyes receiving aflibercept intravitreal (IVT) (Eylea®, aflibercept 2mg) therapy in US clinical practice.
- Trial name
- NCT07105228
- Testing
- aflibercept 2mg
- Where
- United States
- Volunteers
- 290,000 people
- Sponsor
- Regeneron Pharmaceuticals
Contraception
FemBloc® Permanent Contraception - Early Pivotal Trial
Prospective, multi-center, international, non-randomized, two-arm study of subjects undergoing either FemBloc or laparoscopic bilateral tubal sterilization (Control).
- Trial name
- BLOC (NCT03433911)
- Testing
- FemBloc, Laparoscopic bilateral tubal sterilization
- Where
- 12 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Femasys Inc.
Patent Ductus Arteriosus
Post Marketing Clinical Follow Up Study to Evaluate Efficacy and Safety of the Occlutech PDA Occluder in Patients With Patent Ductus Arteriosus Defects
This retrospective and prospective, multicenter, international post marketing follow up study evaluates the safety and efficacy of the Occlutech® PDA Occluder, delivered using the Occlutech Occlusions Pusher (OOP), in subjects…
- Trial name
- NCT05264753
- Testing
- Occlutech® PDA Occluder
- Where
- 15 sites in Canada, France and 7 more
- Volunteers
- 255 people
- Sponsor
- Occlutech International AB
Bifurcation, Percutaneous Coronary Intervention
Plaque mOrphology iMpact on Side Branch Occlusion at oPtical Coherence Tomography Evaluation in Percutaneous Coronary Interventions
Despite recent advances in interventional cardiology, bifurcation coronary artery stenoses (which account for 15-20% of all coronary lesions treated by PCI), remain a challenge for PCI operators with higher rates of failure…
- Trial name
- POMPEI (NCT04501549)
- Testing
- percutaneous coronary intervention
- Where
- Singapore
- Volunteers
- 27 people
- Sponsor
- National Heart Centre Singapore
Dental Occlusion, Traumatic, Edentulous Alveolar Ridge
T-Scan Study of Occlusion in Case of Implant Retained Overdenture
Materials and methods: fourteen patients were selected according to the inclusion criteria, the participants were stratified equally into two groups, patients were assigned to receive either monoplane or lingualized occlusal…
- Trial name
- NCT03887975
- Testing
- Monoplane Occlusion, Lingualized occlusion
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Chronic Total Occlusion of Coronary Artery, Diabetes Mellitus, Type 2
COronary CoLLateralization in Type 2 diabEtic Patients With Chronic Total Occlusion
A severe coronary artery obstruction is a prerequisite for spontaneous collateral recruitment. The formation of coronary collateral circulation(CCC) is significantly impaired in type 2 diabetic patients with chronic total…
- Trial name
- COLLECT (NCT06054126)
- Testing
- Echocardiography
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Ruijin Hospital
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