Clinical trials: Dental Occlusion
Embolism and Thrombosis of the Radial Artery
Radial Artery Occlusion After Endovascular Procedure
Observational cohort registry: prospective, multicenter independent evaluation of patients who undergo coronary angiography and/or PCI via radial artery.
- Trial name
- NCT02762344
- Testing
- heparin
- Where
- Italy
- Volunteers
- 2,168 people
- Sponsor
- Azienda Sanitaria ULSS 13 Dolo, Mirano
Coronary Occlusion
Guidewire for Chronic Total Occlusion
Under the circumstances that appropriate first-choice guidewires for percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) have yet to be established, the objective of this study is to determine appropriate…
- Trial name
- G-FORCE (NCT00987610)
- Testing
- Percutaneous coronary intervention (PCI)
- Where
- 25 sites in Japan
- Volunteers
- 260 people
- Sponsor
- Tokai University
Retinal Vein Occlusion With Macular Edema
Comparison of Therapeutic Effects Between Intravitreal Injection of Bevacizumab With Intravitreal Injection of Bevacizumab and Targeted Laser Photocoagulation of Non Perfused Areas of Retina in Patients With Acute Retinal Vein Occlusion
Patients with new onset retinal vein occlusion in less than 3 month whom has visual acuity less than 20/40 and central macular thickness more than 250micrometer and non perfused areas of retina more than 10 DD are included in…
- Trial name
- bevacizumab (NCT03353324)
- Testing
- intravitreal injection of bevacizumab, intravitreal injection of bevacizumab+ targeted laser
- Where
- Iran
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
DME, Retinal Vein Occlusion (RVO)
AI vs. Physician for Anti-VEGF Decision-Making: An RCT
We developed an artificial intelligence system, called QiLin, which was designed to assist anti-VEGF treatment decisions in retinal diseases.
- Conditions
- DME, Retinal Vein Occlusion (RVO), Neovascular (Wet) Age-Related Macular Degeneration
- Trial name
- NCT07328776
- Testing
- QiLin-assisted, physician only, without QiLin assisted
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Stroke, Occlusion Carotid
Endovascular Revascularization of Symptomatic Chronically Occluded Internal Carotid Artery
This is a phase 2 randomized single-center open label clinical trial with randomization of 1:1 to either best medical management vs. best medical management and endovascular revascularization of chronically occluded ICA (COICA).
- Trial name
- NCT03176420
- Testing
- angioplasty and stenting of occluded cervical ICA
- Sponsor
- University of Iowa
Peripheral Arterial Disease, Peripheral Vascular Disease
Safety and Efficacy of the SurVeil™ Drug-Coated Balloon
To demonstrate the safety and efficacy of the SurVeil Drug-Coated Balloon (DCB) for treatment of subjects with symptomatic peripheral artery disease (PAD) due to stenosis of the femoral and/or popliteal arteries.
- Conditions
- Peripheral Arterial Disease, Peripheral Vascular Disease, Artery Disease, Peripheral, Femoropopliteal Artery Occlusion
- Trial name
- TRANSCEND (NCT03241459)
- Testing
- Surmodics SurVeil DCB, Medtronic IN.PACT Admiral DCB
- Where
- 63 sites in United States, Australia and 7 more
- Volunteers
- 446 people
- Sponsor
- SurModics, Inc.
Ischemic Stroke, Covid 19
Endovascular Thrombectomy in COVID-19 Infected Patients
About 5% of COVID-19 patients may present symptoms related to acute ischemic stroke (AIS). Treatment-management and outcomes related to mechanical thrombectomy (MT) for COVID-19 infected patients harboring large vessel occlusion…
- Trial name
- ET-COVID-19 (NCT04406090)
- Testing
- Mechanical Trombectomy
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Thrombosis, Venous Thrombosis
Safety and Efficacy Study of Alfimeprase in Subjects With Occluded Central Catheters
The purpose of the study is to compare the safety and effectiveness of alfimeprase to a placebo in restoring function of occluded central catheters.
- Trial name
- NCT00346424
- Testing
- Alfimeprase
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- ARCA Biopharma, Inc.
Atrial Fibrillation
Left Atrial Appendage Occlusion Registry (LAAO Registry)
The Left Atrial Appendage Occlusion Registry (LAAO Registry™) is designed to assess the prevalence, demographics, management, and outcomes of patients undergoing percutaneous and epicardial based left atrial appendage occlusion…
- Trial name
- NCT02699957
- Testing
- Left Atrial Appendage Occlusion
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- American College of Cardiology
Coronary Bypass Graft Occlusion
Diagnostic and Prognostic Value of Cardiac Biomarkers for Early Coronary Bypass Occlusion in Patients Undergoing Coronary Revascularization
This study is to evaluate the correlation between hs-cTn level as cardiac biomarker for ischemia and early graft occlusion as assessed by CCT in patients undergoing coronary bypass surgery.
- Trial name
- NCT04595630
- Testing
- data collection from the hospital records
- Where
- 3 sites in Croatia, Poland and 1 more
- Volunteers
- 480 people
- Sponsor
- University Hospital, Basel, Switzerland
Coronary Heart Disease, Diabetes
OPtimized Stenting Using Intravascular Ultrasound(IVUS) in Long lEsion: Rationale for Simplified criteriA
Rationale IVUS has shown to be efficient for bare metal stent deployment, but has not been specifically studied for Drug Eluting Stents.
- Conditions
- Coronary Heart Disease, Diabetes, Vascular Lesions, Chronic Total Occlusion of Coronary Artery
- Trial name
- OPERA (NCT01861860)
- Testing
- TAXUS™ Element long stent
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Acute Ischemic Stroke
Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial
The primary objective is to establish the efficacy of intra-arterial (IA) mechanical thrombectomy (MT) with extracranial proximal carotid artery acute stenting versus non-stenting approaches in patients with acute ischemic stroke…
- Trial name
- PICASSO (NCT05611242)
- Testing
- MT+CAS with IV-AP, MT+CAS with PO-AP, MT+CAT with PO-AP
- Where
- 60 sites in United States
- Volunteers
- 404 people
- Sponsor
- Mercy Health Ohio
Chronic Total Occlusion (CTO), Frontal QRS-T Angle
Relationship Between Frontal QRS-T Angle and Collateral Circulation in Coronary Artery Chronic Total Occlusion
Aim of the work: To examine the relationship between collateral circulation and the frontal QRS-T angle in patients with chronic total occlusion (CTO)
- Trial name
- NCT07743437
- Testing
- 12-lead Electrocardiogram (ECG) and Coronary Angiography
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Temporomandibular Joint Disorders, Occlusion
Relationships Between Anterior and Condylar Guidance - Comparison by CBCT and Electronic Axiography
The aim of the following study was to investigate the existence of a statistically significant correlation between the incisal features (incisal guidance angle, interincisal angle, overbite, overjet), temporomandibular joint…
- Trial name
- NCT05637372
- Testing
- CBCT
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Medical University of Gdansk
Acute Stroke, Mechanical Thrombectomy
BraiN20® Monitoring in Acute Stroke Undergoing Thrombectomy
N20 somatosensory evoked potential (SEP) response shows high predictive accuracy of functional recovery in patients with acute ischemic stroke (AIS) undergoing endovascular thrombectomy (EVT).
- Trial name
- PROMISE20 (NCT06149754)
- Testing
- BraiN20(R) monitoring of N20 somatosensory evoked potential
- Where
- 3 sites in Spain
- Volunteers
- 65 people
- Sponsor
- Fundació Institut Germans Trias i Pujol
Patellofemoral Pain Syndrome, Vascular Occlusion
Muscle Training With and Without Vascular Occlusion of Women With Patellofemoral Pain Syndrome: A Random Clinical Trial
Introduction: The treatment of Patellofemoral Pain Syndrome (PFPS) uses the strengthening of the knee and hip muscles. Studies propose the use of partial vascular occlusion (OVP) of the quadriceps muscle to increase muscle…
- Trial name
- NCT04478422
- Testing
- Muscle strengthening with vascular occlusion, Conventional muscle strengthening
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Christiane Macedo
Central Retinal Vein Occlusion, Branch Retinal Vein Occlusion
Retrospective Study of the Effectiveness and Safety of Niacin and Steroid Eye Drops for Retinal Vein Occlusions
The aim of this study is to develop a less risky, yet effective and more sustainable treatment for retinal vein occlusions than the current commonly used approach of repeated intravitreal triamcinolone acetonide (Kenalog)…
- Trial name
- NCT00500045
- Testing
- nicotinic acid
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Palo Alto Medical Foundation
Retinal Vein Occlusion, Macular Edema
Study of Squalamine Lactate for the Treatment of Macular Edema Related to Retinal Vein Occlusion
This was a prospective, single center, open label, randomized study evaluating the biological effect of squalamine lactate ophthalmic solution, 0.2% combined with intravitreous ranibizumab in patients with macular edema secondary…
- Trial name
- NCT02614937
- Testing
- ranibizumab, Squalamine Lactate Ophthalmic Solution, 0.2%
- Volunteers
- 20 people
- Sponsor
- Ohr Pharmaceutical Inc.
Contraception
Prospective Multi-Center Trial for FemBloc Permanent Birth Control
Prospective, multi-center, international, unblinded, single-arm trial of subjects undergoing FemBloc followed by ultrasound confirmation test.
- Trial name
- FINALE (NCT05977751)
- Testing
- FemBloc
- Where
- 12 sites in United States
- Volunteers
- 573 people, healthy volunteers welcome
- Sponsor
- Femasys Inc.
Exanguination, Polytrauma
Abdominal Aortic Junction Tourniquet (AAJT-S) for Non-compressible Torso Haemorrhage in the Prehospital and Emergency Room Setting
This study seeks to evaluate the feasibility of a Abdominal Aortic Balloon Occlusion of the Aorta (AAJT-S) in exanguinating trauma patients with non-compressible truncal haemorrhage in the emergency room and the pre-hospital…
- Conditions
- Exanguination, Polytrauma, NCTH
- Trial name
- NCT07274150
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Graz
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