Clinical trials: Dental Occlusion
Stroke, Acute Ischemic, Endovascular Procedures
Triage of Patients With Acute Ischemic Stroke Due to Large Vessel Occlusions-2
The objective of this study is to create a comprehensive, real-world, multi-center observational registry of consecutive patients admitted to hospitals with acute ischemic stroke (AIS) caused by large vessel occlusions (LVO), who…
- Conditions
- Stroke, Acute Ischemic, Endovascular Procedures, Large Vessel Occlusion
- Trial name
- TRACK-LVO-2 (NCT05659160)
- Testing
- Endovascular Therapy
- Where
- 4 sites in China
- Volunteers
- 5,000 people
- Sponsor
- Tianjin Huanhu Hospital
Critically Ill Patients, Hemodynamic Instability
Sigh35 and End-expiratory Occlusion Test (EEOT) for Assessing flUid Responsiveness in Critically Ill Patients Undergoing Pressure Support Ventilation
The application of a brief SIGH of 4 seconds at 35 cmH20 has shown to reliably predict fluid responsiveness in critically ill patients undergoing pressure support ventilation.
- Conditions
- Critically Ill Patients, Hemodynamic Instability, Mechanical Ventilation Pressure High
- Trial name
- SETUP (NCT04924920)
- Testing
- SIGH, EEOT, Fluid challenge
- Where
- 2 sites in Italy
- Volunteers
- 60 people
- Sponsor
- Humanitas Clinical and Research Center
Coronary Stent Occlusion
CT-FFR for Coronary In-stent Stenosis Based on ISR-Net Algorithm
CT-FFR(CT-derived flow reserve fraction) usually could not been measured accurately for in-stent lesions due to the serious interference with the metal structs.
- Trial name
- NCT05131191
- Testing
- CT-FFR measurement, invasive FFR
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Beijing Hospital
Cardiovascular Diseases
Endothelial Effects of VEGF Inhibition In Vivo in Man
Recent developments in chemotherapy, particularly VEGF-inhibitor (VEGFI) drugs, have markedly improved the prognosis of patients with cancer.
- Trial name
- ENDEAVOUR (NCT03557190)
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Diabetic Macular Edema, Macular Edema Due to Diabetes Mellitus
OCT and OCT-Angiography Biomarkers of Treatment Response to Dexamethasone Implant in Macular Edema Due to Retinal Vascular Diseases - DME and RVO
The purpose of this pilot study is to evaluate different imaging parameters in patients with previously treatment-naive DME and ME due to RVO before and after treatment with dexamethasone implant, in order to find specific…
- Conditions
- Diabetic Macular Edema, Macular Edema Due to Diabetes Mellitus, Retinal Vein Occlusion
- Trial name
- NCT06332690
- Testing
- dexamethasone implant
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Multimedica
Acute Ischemic Stroke, Large Vessel Occlusion
Sivelestat Sodium as an Adjunct to Endovascular Thrombectomy for Acute Anterior Circulation Large-Vessel Occlusion
Stroke remains a major global health burden, with acute ischemic stroke (AIS) accounting for more than 65% of all cases. Endovascular thrombectomy (EVT) has been established as a standard treatment for large vessel occlusion…
- Conditions
- Acute Ischemic Stroke, Large Vessel Occlusion, Thrombectomy, Neutrophil Extracellular Trap Formation
- Trial name
- NCT07552610
- Testing
- Sivelestat sodium, Endovascular Thrombectomy
- Where
- 2 sites in China
- Volunteers
- 868 people
- Sponsor
- Xuanwu Hospital, Beijing
Coronary Artery Disease, Coronary Artery Chronic Total Occlusion
CrossBoss and Stingray Catheter and Entera Guidewire Chronic Total Occlusion (CTO) Study
This study is to determine if the BridgePoint Medical System (CrossBoss Catheter, Stingray Catheter, Entera Guidewire) can facilitate safe and effective placement of a guidewire in the true lumen of coronary vessels distal to a…
- Trial name
- NCT00801710
- Testing
- BridgePoint Medical System (CrossBoss Catheter, Stingray Catheter, Entera Guidewire)
- Where
- 4 sites in Germany
- Volunteers
- 42 people
- Sponsor
- Boston Scientific Corporation
Disorder of Maxillary and Mandibular Dental Arch Relationship
Impact of Complete Removable Prosthetic Rehabilitations Performed by an Innovative DDTENS Protocol, on the Quality of Masticatory Function and the Management of Completely Edentulous Patients
Total edentulism is a profound physical, psychic and social handicap, which affects 5 million people in France. The most frequent complaint of edentulous patients rehabilitated by conventional Complete Removable Prostheses (CRP)…
- Trial name
- DD-TENS (NCT05096624)
- Testing
- DD-TENS system, Gold Standard, Digital Denture system
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Aortoiliac Occlusive Disease, Stent Complication
BS-CERAB TECHNIQUE
The covered endovascular reconstruction of aortic bifurcation (CERAB) technique was described l in 2013 to reconstruct the aortic bifurcation in a more anatomical and physiological way.
- Conditions
- Aortoiliac Occlusive Disease, Stent Complication, Vascular Device Occlusion, Iliac Artery Stenosis
- Trial name
- BS-CERAB (NCT06012123)
- Testing
- Aortoiliac angioplasty and stenting
- Where
- Spain
- Volunteers
- 21 people
- Sponsor
- Vascular Investigation Network Spanish Society for Angiology and Vascular Surgery
Macular Edema, Retinal Vein Occlusion
A Study of the Safety and Efficacy of a New Treatment for Macular Edema Resulting From Retinal Vein Occlusion
This study will evaluate the safety and efficacy of an intravitreal implant of dexamethasone for the treatment of macular edema associated with retinal vein occlusion.
- Trial name
- NCT00168298
- Testing
- 700 µg Dexamethasone, 350 µg Dexamethasone
- Where
- 13 sites in United States, Brazil and 11 more
- Volunteers
- 668 people
- Sponsor
- Allergan
Dental Caries
Evaluation of Reliability of CarieScan PRO Compared With Digital Radiograph and ICDAS-II in Detection of Carious Lesions
The aim of this study is to evaluate the Clinical performance of alternating current impedance spectroscopy (CarieScan PRO) in comparison with digital radiograph and ICDAS-II in detection of occlusal carious lesions.
- Trial name
- NCT04438252
- Testing
- ICDAS II, CariScan Pro, Digital Radiograpgy
- Where
- Egypt
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cerebral Atherosclerosis
Study on Prevention and Treatment of Atherosclerotic Cerebral Occlusive Disease With Remote Ischemic Conditioning
The primary objective of the study will be to determine whether remote limb ischemic conditioning (RLIC) together with conventional medication therapy compared with only medication therapy reduces the 3-month risk of composite…
- Trial name
- NCT04470492
- Testing
- Doctormate®+Medical Management, Medical Management
- Volunteers
- 700 people
- Sponsor
- Ji Xunming,MD,PhD
Cerebrovascular Disorders, Acute Cerebrovascular Disease
Inhaled Nitric Oxide in Acute Ischemic Stroke Patients Undergoing Mechanical Thrombectomy
The purpose of this study is to determine the safety and feasibility of using inhaled nitric oxide (iNO) in patients undergoing intra-arterial mechanical thrombectomy (blood clot extraction or IAMT) for treatment of acute…
- Trial name
- iNO (NCT05871606)
- Testing
- iNO
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Wake Forest University Health Sciences
Coronary Artery Disease, Chronic Total Occlusion of Coronary Artery
DYNAMX Bioadaptor ImplanTation for the trEatment of Complex Coronary Lesions
The aim of the DYNAMITE study is to investigate the (a) acute procedural and (b) 9-month follow-up performance of DynamX Drug-Eluting Coronary Bioadaptor System implantation in complex coronary lesions.
- Conditions
- Coronary Artery Disease, Chronic Total Occlusion of Coronary Artery, Bifurcation of Coronary Artery, Multi Vessel Coronary Artery Disease
- Trial name
- DYNAMITE (NCT05464147)
- Testing
- DynamX Drug-Eluting Coronary Bioadaptor System
- Where
- Italy
- Volunteers
- 55 people
- Sponsor
- Elixir Medical Corporation
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III Hungary Satellite Registry
This registry is a clinical post-market evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES)
- Trial name
- NCT01892917
- Where
- 13 sites in Hungary
- Volunteers
- 2,000 people
- Sponsor
- Biotronik Hungária Kft.
CVD
Argatroban for Preventing Occlusion and Restenosis After Extracranial Vertebral Artery Stenting
Argatroban is a selective thrombin inhibitor, and previous study had suggested that argatroban use post percutaneous coronary intervention could potentially prevent reocclusion.
- Trial name
- NCT01980316
- Testing
- Argatroban, non-argatroban treated group
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Xinfeng Liu
Ischemic Stroke
Cerebellar Infarct Volume in Basilar Artery Stroke
Preprocedural predictors of outcome in patients with acute basilar artery occlusion (ABAO) who underwent endovascular treatment (EVT) remain controversial.
- Trial name
- CIV-ABAO (NCT04611178)
- Testing
- Mechanical thrombectomy
- Where
- France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Montpellier
Anisometropic Amblyopia, Strabismic Amblyopia
3D Movie Viewing vs Occlusion for Treating Amblyopia in Children
Amblyopia is a common childhood visual disorder that affects vision in one eye and can also impair depth perception (stereopsis).
- Trial name
- VISTA3D (NCT07563946)
- Testing
- 3D Movie Viewing, Occlusion Therapy
- Volunteers
- 56 people
- Sponsor
- Universitat Politècnica de Catalunya
Crowding, Tooth
The Effectiveness of Clear Aligner and Traditional Fixed Appliances in Achieving Good Occlusion in Complex Orthodontic Cases
Patients who have severe crowding that requires four premolars extraction will be treated in this study. The efficacy and effectiveness of in-house clear aligners therapy compared with vestibular fixed appliances in the treatment…
- Trial name
- NCT05500456
- Testing
- Clear aligners, Fixed appliances
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Retinal Vein Occlusion With Macular Edema
Efficacy and Safety Evaluation of SMO1 in Patients With Retinal Vein Occlusive Macular Edema
This is a multicenter, randomized, double-masked, parallel-group, active-controlled Phase 3 clinical trial designed to evaluate the efficacy and safety of SMO1 (Dexamethasone 700μg intravitreal implant) compared with the…
- Trial name
- NCT07708142
- Testing
- Reference Drug, SMO1
- Where
- South Korea
- Volunteers
- 312 people
- Sponsor
- SANGMYUNG innovation
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