Clinical trials: Dental Plaque Accumulation
Dental Plaque
Effect of Enzymes on Dental Biofilm Accumulation in Healthy Individuals
The purpose of the study is to assess the effect of enzyme containing lozenges on dental plaque accumulation in healthy adults.
- Trial name
- NCT05082103
- Testing
- Enzyme lozenge 1, Enzyme lozenge 2
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Novozymes A/S
Dental Plaque, Gingivitis
A Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste With a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation
The aim of this study is to assess the ability of a marketed Cetylpyridinium Chloride (CPC) mouthwash alongside a marketed Stannous Fluoride (SnF2) toothpaste in improving gingival health and reducing plaque accumulation…
- Trial name
- NCT06660069
- Testing
- Stannous Fluoride Toothpaste (Parodontax Complete Protection Toothpaste), CPC Mouthwash (Parodontax Active Gum Health Mouthwash), Regular Fluoride Toothpaste (Crest Cavity Protection)
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- HALEON
Dental Plaque Accumulation, Oral Hygiene in Orthodontic Patients
Comparison of Plaque Removal Efficacy of Different Toothbrushes in Clear Aligner Patients
This study aims to compare the effectiveness of manual and powered toothbrushes in removing dental plaque in patients undergoing clear aligner orthodontic treatment.
- Conditions
- Dental Plaque Accumulation, Oral Hygiene in Orthodontic Patients, Clear Aligner Therapy
- Trial name
- NCT07383636
- Testing
- Manual Toothbrush, Powered Toothbrush
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Mersin University
Dental Caries, Dental Plaque Accumulation
Miswak (Salvadora Persica) Versus a Toothbrush in Plaque Removal
The study investigates the effectiveness of a 45°-cut miswak for plaque removal compared to a toothbrush in children and assesses their preferences for these tools.
- Trial name
- NCT07409610
- Testing
- Miswak, Toothbrush
- Where
- Saudi Arabia
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Gingival Inflammation, Dental Plaque Accumulation
Evaluation of the Anti-plaque Effect of a Bioflavonoid-based Antiseptic Mouthwash
This study evaluates the antiplaque efficacy of a bioflavonoid-based mouthwash compared to a positive control (0.12% chlorhexidine mouthwash).
- Trial name
- NCT07824388
- Testing
- Bioflavonoid mouthwash, Chlorhexidine 0.12% mouthwash
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Plaque Induced Gingival Disease, Oral Health
Effect of Benzydamine Hydrochloride Mouthrinse on Plaque Accumulation in Periodontally Healthy Female Subjects
The goal of this clinical trial is to evaluate the effect of a mouthrinse containing an active ingredient benzydamine hydrochloride in the absence of daily oral hygiene.
- Trial name
- BHCl-PLAQUE (NCT07565766)
- Testing
- Benzydamine hydrochloride mouthrinse
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Dental Plaque Accumulation
In Situ Evaluation of Plaque Accumulation on Innovative Nanostructured Metal Implant Surfaces
Participants will get a customized maxillary tray carrying 2 pairs of metal disks with a nanostructured surface. They will wear the trays continuously for 72 hours except when eating, drinking or brushing their teeth.
- Trial name
- INDIS (NCT07784803)
- Testing
- Maxillary tray
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Malmö University
Dental Plaque Induced Gingivitis, Dental Plaque
A Comparative Study of Electric Toothbrushes for the Efficacy Plaque Removal and the Effect on Plaque Accumulation and Gingivitis.
It is well accepted that the greatest contributor to the health of the periodontium and dentition is regular and thorough dental plaque removal, typically by means of adequate toothbrushing.
- Trial name
- NCT03416985
- Testing
- Oral B Healthy Clean Manual Toothbrush, BURST Sonic Oral Care, Philipps Sonicare DiamondClean 300 Series
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Gingival Hyperplasia, Dental Plaque
Clinical Efficacy of Chlorhexidine Varnish in Reducing Gingival Hyperplasia, Plaque Accumulation, and White Spot Lesions in Orthodontic Patients
This study investigates whether applying a chlorohexidine varnish (a dental coating) reduces gum overgrowth, plaque buildup, and early tooth decay (white spots) in patients with braces.
- Conditions
- Gingival Hyperplasia, Dental Plaque, Tooth Demineralization
- Trial name
- NCT07115784
- Testing
- Chlorhexidine Varnish
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Dental Plaque, Gingival Bleeding
Comparison Between Interdental Brush and Water Floss on Plaque Accumulation and Gingival Inflammation in Patients Undergoing Fixed Orthodontic Treatment.
The goal of this clinical trial is to test the ability of water flosser to remove plaque and reduce gingival inflammation in patients undergoing fixed orthodontic treatment.
- Trial name
- NCT07240428
- Testing
- Interdental brush, Water floss
- Where
- Jordan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Dental Plaque, Gingivitis
A Clinical Study to Evaluate the Effectiveness of an Experimental Toothpaste in Improving Gum Health and Reducing Plaque Accumulation
The aim of this 24-week clinical study is to evaluate the ability of an experimental dentifrice containing 0.454 percent (%) weight by weight (w/w) Stannous fluoride (SnF2); to improve gingival health, plaque reduction and…
- Trial name
- NCT07255040
- Testing
- Test Dentifrice, Parodontax Complete Protection, Colgate Cavity Protection
- Where
- United States
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- HALEON
Dental Plaque Accumulation, Oral Hygiene Education
Mosque-based Oral Health Intervention Using Solomon Design
This quasi-experimental study evaluates a mosque-based oral health education intervention ("Smile With Prophet", SWP) among adult male mosque attendees in Dhaka, Bangladesh, using a Solomon four-group design.
- Trial name
- NCT07584512
- Testing
- Smile With Prophet (SWP)
- Where
- 2 sites in Bangladesh
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Gingival Bleeding, Dental Plaque Accumulation
Adjunctive Oral Hygiene Aids in Reducing Oral Hygiene Parameters Among Orthodontic Patients
Adult orthodontic patients aged 18-30 were included in a randomised, singleblind clinical research using a split-mouth design at a dental clinic.
- Trial name
- D-F-H-17-Dec (NCT06779279)
- Testing
- Water flosser and super flosser, Orthodontic brush
- Where
- United Arab Emirates
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- sudhir rama varma
Periodontal Health, Dental Plaque Accumulation
Effects of Probiotics on Oral Health
Some probiotics have been shown to have preventive effects on infectious diseases and allergies. Because their long-term enhancement of the immune responses of children, they have been recommended for infants in some countries.
- Trial name
- NCT02444182
- Testing
- Probiotics
- Where
- Kuwait
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Kuwait University
Gingivitis, Dental Plaque Accumulation
Study of an Essential Oil and a Delmopinol Mouthrinse Effect on Dental Plaque Accumulation Index, Gingivitis Index and on Streptococcus Mutans, Lactobacillus, Aerobic and Anaerobic Oral Bacteria Colony Counts.
The use of mouthrinses may be of relevance as a complement to daily dental hygiene procedures, especially for patients who do not comply with a proper mechanical removal of dental plaque.
- Trial name
- NCT01236950
- Testing
- Essential oils mouthrinse, Delmopinol mouthrinse
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Gingivitis, Plaque
ToothWave Calculus Reduction and Accumulation Prevention Study
The objective of the study is to evaluate the safety and efficacy of the home-use device ToothWave (Model H7001) for calculus reduction and the prevention of calculus accumulation.
- Conditions
- Gingivitis, Plaque, Calculus, Dental
- Trial name
- NCT04596761
- Testing
- RF-utilizing powered toothbrush
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Home Skinovations Ltd.
Dental Plaque, Gingivitis
Effect of an Enzyme-containing Lozenge on Dental Biofilm in Healthy Individuals.
The purpose of the study is to assess the effect of an enzyme containing lozenge on dental plaque accumulation in healthy adults.
- Conditions
- Dental Plaque, Gingivitis, Microbial Colonization
- Trial name
- NCT05070507
- Testing
- Enzyme containing lozenge
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Novozymes A/S
Gingivitis, Dental Plaque Accumulation
6-month Clinical Investigation Assessing the Efficacy of an Antimicrobial Mouthrinse in Reducing Established Plaque and Improving Gum Health
The goal of this clinical trial is to evaluate the clinical efficacy of an antimicrobial mouthrinse, with a particular focus on its effect on established plaque and the improvement of gum health.
- Trial name
- NCT07414173
- Testing
- Test Mouthrinse, Control Mouthrinse
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Plaque, Dental Plaque Accumulation
Effect of Different Products to Support Plaque Control During Daytime
The goal of this clinical trial is to test if the additional use of different commercially available products for a better breath and plaque reduction, taken during daytime between morning and evening tooth brushing, can reduce…
- Conditions
- Dental Plaque, Dental Plaque Accumulation, Mouthwashes, Chewing Gum
- Trial name
- NCT07382310
- Testing
- Oral B Pro-Health Multi-Protection Mouth Rinse refreshing mint without alcohol (0.07% CPC), Listerine Total Care mouth rinse without alcohol, Colgate total advanced pro-shield mouth rinse without alcohol (0.075% CPC)
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Pocket Depth, Plaque Accumulation
Microbial and Periodontal Changes Associated With Conventional Versus Self Ligating Brackets
Microbial and periodontal changes associated with conventional versus self ligating brackets. The aim of this study will be to compare microbial and periodontal changes associated with conventional versus self ligating brackets.
- Conditions
- Pocket Depth, Plaque Accumulation, Gigival Bleeding
- Trial name
- NCT02436525
- Testing
- conventional stainless steel orthodontic brackets ligated with stainless steel ligature (Oromco - USA), passive self-ligating stainless steel orthodontic brackets (Oromco - USA), active self-ligating stainless steel orthodontic brackets (Oromco - USA)
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University