Clinical trials: Dental Prophylaxis
Caries,Dental, Tooth Decay
KAP of Dental Practitioners Regarding CRA
The aim of the study is to evaluate the knowledge, attitude, and practice of a group of dental practitioners from Cairo and Riyadh regarding caries risk assessment and management.
- Conditions
- Caries,Dental, Tooth Decay, Tooth Diseases
- Trial name
- NCT05792215
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Early Childhood Caries Prevention: Effectiveness of Mother-Child Oral Health Care Programme (BASIS)
The goal of this two-arm, parallel-group cluster randomized controlled trial was to assess the effectiveness of the mother-child initiated oral health care program, termed BASIS, in preventing early childhood caries (ECC).
- Trial name
- NCT06944977
- Testing
- Anticipatory guidance and postnatal home visits, Anticipatory guidance
- Where
- Malaysia
- Volunteers
- 154 people
- Sponsor
- NORKHAFIZAH SADDKI
Dental Care
Improving Show Rates in Dental Care Settings Serving Underserved Populations
The goal of this study is to compare different no-show interventions in dental clinics serving underserved populations. The main question it seeks to answer is How do different no-show intervention methods compare in reducing…
- Trial name
- NCT06581250
- Testing
- Reminder Messages, Walk-in Visits, Motivation-enhanced Communication
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Dental Caries Extending Into Dentin, Root Caries
Root Caries Excavation with Air Water/powder Prophylaxis Device for ART Restorations
The main objective of this RCT is to compare the efficacy of a powder/water jet prophylaxis device and conventional hand excavation in excavating root surface caries, with regard to restoration survival/success in older adults.
- Trial name
- ART-AIRFLOW (NCT04822246)
- Testing
- Control: Hand instrumentation for caries excavation, Intervention 1: EMS Airflow device for caries excavation, Intervention 2: Hand excavation + EMS Airflow device for caries excavation
- Where
- Switzerland
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Murali Srinivasan, Dr. med. dent., BDS, MDS, MBA, MAS
Infective Endocarditis (IE), Heart Valve Disease
The Study Tests if Preoperative Dental Screening is Superior to no Preoperative Dental Screening in Improving the Outcome of Patients Undergoing Surgical Cardiac Valve Replacement or Transcatheter Cardiac Valve Implantation.
This randomized, multicenter, open-label trial evaluates whether preoperative dental screening improves outcomes in patients undergoing surgical or transcatheter cardiac valve intervention.
- Trial name
- SMILE (NCT07511673)
- Testing
- Preoperative dental screening, No preoperative dental screening
- Where
- 5 sites in Sweden
- Volunteers
- 1,300 people
- Sponsor
- Region Skane
Dental Caries
Glass Ionomer Sealant and Fluoride Varnish Study to Prevent Early Childhood Caries
The goal of this project is to conduct a community-based randomized clinical trial to compare the caries prevention efficacy of fluoride varnish applied every six months vs.
- Trial name
- GIFVT (NCT01129440)
- Testing
- Fluoride Varnish, Glass Ionomer Sealant
- Where
- United States
- Volunteers
- 597 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Preterm Birth, Periodontal Disease
Saving Lives at Birth: Primary Prevention of Periodontal Disease in Relation to Preterm Birth in Malawi
The hypothesis of the investigators' project is that comprehensive primary preterm birth prevention, inclusive of maternal oral health with xylitol chewing gum (the intervention), will reduce the rate of periodontal disease and…
- Conditions
- Preterm Birth, Periodontal Disease, Caries, Dental
- Trial name
- PPaX (NCT02333227)
- Testing
- Xylitol gum
- Where
- United States
- Volunteers
- 10,069 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Mouthguard Use Orofacial Injuries Prevention 3D Printed Mouthguard Traditional Custom-made Mouthguard Occlusal Thickness Changes
Comparative Assessment of Thickness Changes in 3D-Printed vs. Custom-Made Mouth Guards for Children in Contact Sports
This study aims to compare changes in the thickness of traditional and 3D-printed custom mouth guards in pediatric athletes who participate in contact sports.
- Trial name
- NCT07000435
- Testing
- 3D printed custom-made mouth guards, Traditional custom-made mouth guards
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries
Fluoride Concentration in Inter-proximal Fluid From Dental Sealants
The hypothesis of this study is that the concentration of fluoride in oral interproximal fluids would increase more after using high-viscosity GIC as pit and fissure sealant, compared to Resin-Based sealants containing fluoride…
- Trial name
- NCT01588210
- Testing
- Sealant application
- Where
- 2 sites in Italy
- Volunteers
- 2,776 people
- Sponsor
- Università degli Studi di Sassari
Dental Plaque
Evaluate Dental Plaque Benefit of a Preventive Treatment Gel
The objective of the study is to evaluate anti-plaque efficacy of a preventive treatment gel in a modified 4-day plaque model.
- Trial name
- NCT03546491
- Testing
- Preventive Gel, Marketed Control
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Injection Pain, Local Anesthesia Infiltration
Sweet-Tasting Solution Versus Placebo to Reduce Pain During Local Anesthetic Injection in Children
The goal of this clinical trial is to learn whether applying a sugar-free flavored sweet solution (SFSS) before local anesthesia helps reduce injection pain in children.
- Conditions
- Injection Pain, Local Anesthesia Infiltration, Pain, Injection Pain Prevention
- Trial name
- NCT07279285
- Testing
- Sugar-free-flavored sweet tasting solution
- Where
- Jordan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Dental Caries in Children
The Effectiveness of Dental Health Home Visits on Caries Prevention in Young Children
Tooth decay affects 75% of Malaysian preschool children, most of which remain untreated. Untreated decay can cause pain, and impair nutritional status and physical growth.
- Trial name
- NCT04885348
- Testing
- Intervention Group (Dental Home Visits + Dental Home Education Leaflets), Control Group (Dental Home Education Leaflets)
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Ministry of Education, Malaysia
Liver Cirrhosis, Coagulopathy
Prevention of Bleeding in Patient With Cirrhosis Undergoing Dental Extraction
The purpose of this study is to investigate how effective and cost saving 1-deamino-8-D-arginine vasopressin (desmopressin, DDAVP) is as opposed to the transfusion of blood products in preventing bleeding after teeth extraction…
- Trial name
- NCT00816127
- Testing
- Desmopressin, blood transfusion
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Dental Caries, Oral Health Behavior Change
Assessing the Impact of a Social Media-Based Educational Intervention Using WhatsApp Video Messages on Dental Caries Prevention Knowledge, Oral Hygiene Practices, and Attitudes Toward Dental Health Among Primary School Children Aged 10-12 Years in Public Schools in Cairo Governorate, Egypt: A Quasi-
The goal of this study is to learn if educational videos sent through WhatsApp can improve dental health knowledge, healthy habits, and attitudes in primary school children aged 10 to 12 years in Cairo, Egypt.
- Conditions
- Dental Caries, Oral Health Behavior Change, Oral Hygiene, Oral Health, Knowledge, Attitudes, Practice
- Trial name
- NCT07363317
- Testing
- WhatsApp-Based Dental Health Education for Children
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Rana Mohamed Ahmed Farghal
Dental Caries
Personalized Caries Management Versus Standard of Care for Preventing Incidence of Caries in Young Egyptian Adults
Basic standard of care emphasis only tooth brushing and flossing without addressing individual pathological factors. For this reason, randomized controlled clinical trials on personalized caries management are needed to be able…
- Trial name
- NCT03731780
- Testing
- Personalized Treatment, Chlorhexidine and Remineralization, Control
- Where
- Egypt
- Volunteers
- 81 people
- Sponsor
- Cairo University
Dental Caries in Children
Effect of Sugar-Free Chewing Gum Containing Tulsi Extract on Salivary Streptococcus Mutans in a Group of Children
The goal of this clinical trial was to explore how adding Tulsi extract, a natural plant substance, to chewing gum affects the levels of Streptococcus mutans, type of bacteria that cause dental caries, in the saliva of children…
- Trial name
- NCT06174194
- Testing
- Tulsi Gum
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Faculty of Dental Medicine for Girls
Caries,Dental, Head and Neck Cancer
Prevention of Caries in Head and Neck Cancer Survivors Who Underwent Radiotherapy
One of the long-term side effects of head and neck radiotherapy (RT) is radiation-induced tooth decay. Hyposalivation, associated with radiation therapy, further increases caries susceptibility and caries progression, due to the…
- Conditions
- Caries,Dental, Head and Neck Cancer, Radiotherapy; Complications
- Trial name
- RADIOCARIES (NCT06308796)
- Testing
- Application of CaP dental mousse
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Milan
Dental Caries
Effective Fluoride Concentration In Toothpaste For Dental Caries Prevention
to identify the Effective Fluoride Concentration In Toothpaste For Dental Caries Prevention after 18 months of randomized controlled trial.
- Trial name
- DMFT (NCT02016001)
- Testing
- toothpaste 1 with maximum fluoride concentration, toothpaste 2 with 1000 ppm of fluoride
- Where
- Pakistan
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
X-linked Hypophosphatemia (XLH)
Prevention of Spontaneous Dental Abscesses in Children With X-linked Hypophosphatemia : a RCT
This study is a prospective, randomized, single-blind, split-mouth, national multicenter trial, comparing the efficacy of a self-etch adhesive system combined (SAM) with a flowable composite to that of a fluoride varnish for the…
- Trial name
- PRADEX (NCT04872907)
- Testing
- adhesive system, fluoride varnish, flowable composite
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dental Plaque
A Four-Week Study to Measure the Effectiveness of an Experimental Mouthwash Used After Teeth Cleaning
This study will test the idea that using an experimental mouth rinse after each time you brush your teeth will result in a healthier mouth than using the regular mouth rinse.
- Trial name
- NCT01462110
- Testing
- 19416-154-1, W002194-0221P
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide