Clinical trials: Dental Treatment
Healthy Adults, Plaque, Dental
Photodynamic Treatment in the Management of Residual Biofilm - a Crossover Study
This research introduces a home-use dual-light antibacterial medical device and its possible added value as part of traditional dental self-care.
- Trial name
- NCT06860321
- Testing
- Adjunct antibacterial home-use dual-light medical device, Regular oral self care
- Where
- Finland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Koite Health Oy
Moderate Pain, Severe Pain
Efficacy and Safety of DIT112 in the Treatment of Moderate to Severe Pain After Dental Surgery for the Extraction of Impacted Third Molars
The purpose of this study is to evaluate the efficacy and safety of DIT112 in adolescents and adults with acute pain after dental surgery for the extraction of impacted third molars.
- Trial name
- ALIV (NCT06237231)
- Testing
- DIT112, DIPYRONE, TRAMADOL
- Volunteers
- 252 people
- Sponsor
- EMS
Dental Implant, Hydroxyapatite
Clinical Study of Implants With Modified Surface Treatment
The observed medical device in this study were SGS P7D Dental implant. The device replaces the lost tooth root, and provides support for the dental bridges and crowns, or overdenture replacements.
- Trial name
- NCT06034171
- Testing
- dental implant
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- SmileDent Kft.
Pain, Postoperative Pain
Dose-Response Study of MR-107A-01 in The Treatment of Post-Surgical Dental Pain
MR-107A-01 is being studied to investigate its efficacy, safety, and dose-response after dental surgery.
- Conditions
- Pain, Postoperative Pain, Pain, Acute
- Trial name
- NCT04571515
- Testing
- MR-107A-01
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Mylan Inc.
Dental Cares Under Kalinox's Inhalation
Interest of Re-oxygenation After Inhalation of 50% Nitrous Oxide / 50% Oxygen Premix in Dental Cares
The usefulness of re-oxygenation after inhalation of 50% nitrous oxide and 50% oxygen premix (Kalinox 170 bar) during dental care is studied and the pollution resulting from administration of Kalinox is also investigated.
- Trial name
- NCT00643786
- Testing
- Oxygène, Air Médical
- Where
- France
- Volunteers
- 128 people
- Sponsor
- Air Liquide Santé International
Anesthesia
Comparison of Intranasal Kovacaine Mist, and Placebo for Anesthetizing Maxillary Teeth in Pediatric Patients
The purpose of this study is to compare the efficacy of Kovacaine Mist, and Placebo for inducing pulpal anesthesia of the maxillary teeth in pediatric patients.
- Trial name
- NCT01844830
- Testing
- Tetracaine HCl 3% and Oxymetazoline HCl 0.05%
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- St. Renatus, LLC
Dental Research, Orthodontics
Treatment of the Mandibular Dental Crowding With and Without Corticotomy Surgery
The use of corticotomy surgery in addition to orthodontic standard treatment could accelerate the treatment. Corticotomy involves vertical interdental incisions of the gingiva and the bone with a very low thickness.
- Conditions
- Dental Research, Orthodontics, Surgery, Oral, Maxillofacial Surgery
- Trial name
- CORTICO (NCT03967002)
- Testing
- Test group with corticotomy surgery
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ardentis Cliniques Dentaires
Dental Caries
Oral-Spray Bacillus Spore Probiotic in Preventing and Supporting Treatment of Dental Caries in Children
Despite advances in oral health care, cavities remain highly prevalent worldwide, especially among children. Conventional treatment methods focus on removing damaged tooth tissue but fail to completely eliminate or control…
- Trial name
- NCT07241052
- Testing
- oral-spray 0.9% NaCl physiological saline solution, Smile Care
- Where
- Vietnam
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Anabio R&D
Partial Edentulism, Tooth Disease
Assessment of the Effect of a Novel Surface Roughness Treatment on Dental Implants on Integration Success
A study where dental implants with different roughened surfaces will be evaluated for the ability to resist countertorque forces.
- Trial name
- Luna (NCT01529801)
- Testing
- Osseotite Certain Tapered Group A, Osseotite Certain Tapered Group B, Osseotite Certain Tapered Group C
- Where
- Chile
- Volunteers
- 80 people
- Sponsor
- ZimVie
Post-surgical Oral Wounds, Oral Cavity Surgery
Evaluation of the Performance and Safety of a Linear Hyaluronic Acid-Based Medical Device in the Treatment of Surgical Wounds in the Oral Cavity.
The PR-DENT study is an interventional, single-center, controlled clinical investigation aimed at evaluating the clinical performance and safety of a Class III medical device based on linear hyaluronic acid for the treatment of…
- Conditions
- Post-surgical Oral Wounds, Oral Cavity Surgery, Wound Healing/Regeneration, Dental Extraction Sites
- Trial name
- PR-DENT (NCT07421934)
- Testing
- Intervention: Linear Hyaluronic Acid (Gumblast), Control: Standard Surgical Procedure
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- The Wave Innovation Group s.r.l.
Teeth, Endodontically-Treated
Safety and Efficacy of Using the Endodontic Self Adjusting File - SAF for Root Canal Treatment
The study's primary goal is to assess the safety of the SAF (Self Adjusting File) device for root canal treatments. The study's secondary goal is to evaluate the effectiveness of the SAF device for root canal treatments
- Trial name
- NCT00497042
- Testing
- Self Adjusting File
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ReDent Nova
Anesthesia
Dose-Ranging Study of Intranasal Kovacaine Mist in Pediatric Subjects
The purpose of this study is to assess the efficacy and safety of intranasally administered Kovacaine Mist for anesthetizing maxillary teeth in pediatric subjects.
- Trial name
- NCT01701505
- Testing
- 400uL of Kovacaine Mist, 200uL of Kovacaine Mist, 120uL of Kovacaine Mist
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- St. Renatus, LLC
Huntington Disease
Dose-response Evaluation of the Cellavita HD Product in Patients With Huntington's Disease
Cellavita HD is a stem-cell therapy for Huntington's Disease. This is a prospective, phase II, single-center, randomized (2:2:1), triple-blind, placebo controlled study, with two test doses of Cellavita HD product.
- Trial name
- ADORE-DH (NCT03252535)
- Testing
- Cellavita HD lower dose, Cellavita HD higher dose
- Where
- Brazil
- Volunteers
- 49 people
- Sponsor
- Azidus Brasil
Chronic Periodontitis
Efficacy and Safety of a Commercially Available Injectable Hyaluronic Acid Dental Filler for Periodontal Pockets
This is a controlled, randomized, single-blinded, multicenter, prospective clinical study. In addition to the standard periodontal treatment procedure on all teeth that need to be treated, the 4 teeth with the deepest pockets…
- Trial name
- NCT02391974
- Testing
- PERIOSYAL FILL
- Where
- 3 sites in Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Pain
A Study of Ibuprofen (IBU) 250mg/APAP 500mg In The Treatment Of Post-Surgical Dental Pain
This study is being conducted to determine the overall analgesic efficacy and safety of a fixed-dose ibuprofen 250 mg / acetaminophen 500 mg formulation compared to placebo in subjects who are experiencing post operative pain…
- Trial name
- NCT02837952
- Testing
- FDC IBU/APAP 250 mg/500 mg
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Pfizer