Clinical trials: Dental Treatment
Tooth Extraction
Tranexamic Acid To Reduce Bleeding in Patients Treated With New Oral Anticoagulants Undergoing Dental Extraction
In patients treated with direct oral anticoagulants, bleeding events during or after tooth extraction can lead to unscheduled interruption of the antithrombotic treatment and a potential increased risk of thrombo-embolic events.
- Trial name
- EXTRACT-NOAC (NCT03413891)
- Testing
- Tranexamic Acid
- Where
- Belgium
- Volunteers
- 222 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
One-Piece Dental Implant, Bone-Level Implant
Inflammatory Biomarkers, Microbial Findings, and Clinical Characteristics Before and After Treatment of Peri-Implant Mucositis Around One-Piece and Two-Piece Dental Implants
The goal of this clinical study was to learn whether the design of a dental implant affects how the gums around it respond to treatment of peri-implant mucositis, an early and reversible inflammation of the soft tissue around a…
- Conditions
- One-Piece Dental Implant, Bone-Level Implant, Two-Piece Dental Implant, Nonsurgical Mechanical Debridement
- Trial name
- 1PvsBL (NCT07892313)
- Testing
- Nonsurgical Mechanical Debridement With 1% Chlorhexidine Gel
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Cuneyt Asim Aral
Dental Caries
Retention Rate And Caries Prevention Of Giomer Based Sealant With And Without Pre-Treatment With Bioactive Glass Air Abrasion In Young Adults
Prevention of oral diseases is preferable to treatment and is the key method of achieving cost effectiveness for oral health improvement programs.
- Trial name
- NCT06003452
- Testing
- surface treatment with Bioactive Glass Air Abrasion
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Anxiety
Midazolam Sedation in Dentally Anxious Patients
Use lay language. To compare patient level of cooperation during dental care under conscious sedation with midazolam according to the administration route
- Trial name
- NCT01874717
- Testing
- Conscious sedation for dental care, midazolam
- Where
- France
- Volunteers
- 131 people
- Sponsor
- University Hospital, Clermont-Ferrand
Single Posterior Crowns, Badly Decayed Teeth, Teeth Restored With Large Filling Restorations or Endodontically Treated Teeth
One Year Clinical Evaluation of Milled BioHPP Polyetheretherketone (PEEK)-Based Versus Metal Ceramic Single Crowns
Although the metal-ceramic system is still widely used to fabricate crowns and fixed partial dentures and is considered as the standard treatment in dentistry, aesthetic concerns have stimulated the development of new dental…
- Conditions
- Single Posterior Crowns, Badly Decayed Teeth, Teeth Restored With Large Filling Restorations or Endodontically Treated Teeth, Malformed Teeth, Malposed Teeth (Tilted, Over-erupted, Rotated, Etc.) or Spacing Between Posterior Teeth
- Trial name
- NCT03685513
- Testing
- BioHPP PEEK-based single posterior crowns, Metal ceramic single posterior crowns
- Volunteers
- 46 people
- Sponsor
- Cairo University
Root Caries
Evaluation of Corrective Surgery Versus Dental Implants in Compromised Upper Molars
This study seeks to assess the clinical, radiographic, and patient-reported outcomes of root amputation versus implant over a 12 months period, generating robust evidence to guide clinical decision-making and enhance patient care.
- Trial name
- NCT07608497
- Testing
- root amputation
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Tooth Loss
Bone Tissue Engineering Using Autologous Bone Repair Cell (BRC) Therapy for Sinus Floor Bone Augmentation
The purpose of this research is to determine if one's own bone marrow tissue can help regenerate (grow) bone in the area of the jaw where an implant will be placed.
- Trial name
- NCT00980278
- Testing
- Sinus lift augmentation and dental implant, Aastrom BRCs
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Michigan
Artificial Intelligence (AI) in Diagnosis, Artificial Intelligence Supported Image Reviewing
The Impact of Artificial Intelligence on Dentists' Decision-Making Process During Caries Detection
This study aims to evaluate the influence of artificial intelligence (AI) on the decision-making process for intervention after caries lesion detection.
- Trial name
- DECIDE-AI (NCT07027189)
- Testing
- Artificial intelligence in diagnosis
- Where
- Netherlands
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Dental Root Sensitivity
Propolis as a Treatment for Cervical Dentin Hypersensitivity
Fluoridated desensitizers the frequently used for the treatment of dentin hypersensitivity (DH) with Iontophoresis. This study aimed to evaluate and compare the immediate and long-term effects of 10% Propolis with 2% sodium…
- Trial name
- NCT05588518
- Testing
- desensitizing agents -10% Propolis
- Where
- Saudi Arabia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- King Khalid University
Child Autism
Effect of Modified Dental Visual Aids on Behavior Management During Dental Treatment in Children With Autism Spectrum Disorder
There is a need to find an approach that is appropriate for managing children with Autism Spectrum Disorder in the dental clinic, to manage their behaviour and decrease their anxiety in this research we will apply our modified…
- Trial name
- NCT04576559
- Testing
- Modified dental visual aids, Regular dental visual aids
- Where
- Saudi Arabia
- Volunteers
- 64 people
- Sponsor
- King Abdulaziz University
Obstructive Sleep Apnea, Adverse Effects
Comparison of Nasal Positive End Expiratory Pressure Valve to Dental Device as an Alternative Treatment for Obstructive Sleep Apnea
Determine the clinical efficacy in terms of Apnea Hypopnea Index (AHI), excessive daytime sleepiness (EDS), nocturnal oxygenation of a nasal Positive end-expiratory pressure (PEEP) valve "Provent" in obstructive sleep apnea.
- Trial name
- NCT01553383
- Testing
- nasal peep valve "Provent"
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- Chinese University of Hong Kong
Dental Research, Orthodontics
Treatment of the Mandibular Dental Crowding With and Without Corticotomy Surgery
The use of corticotomy surgery in addition to orthodontic standard treatment could accelerate the treatment. Corticotomy involves vertical interdental incisions of the gingiva and the bone with a very low thickness.
- Conditions
- Dental Research, Orthodontics, Surgery, Oral, Maxillofacial Surgery
- Trial name
- CORTICO (NCT03967002)
- Testing
- Test group with corticotomy surgery
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ardentis Cliniques Dentaires
Edentulous Mouth, Edentulous Jaw
Simplified vs. Conventional Methods for Complete Denture Fabrication
BACKGROUND: The fabrication of complete dentures traditionally involves a series of complex technical procedures. Those procedures include two impressions for each jaw, the registration of the relationship between the upper teeth…
- Trial name
- NCT01230320
- Testing
- Denture fabrication technique
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Medication Related Osteonecrosis of the Jaw
Comparing Implant Retention Versus Removal for MRONJ at Implant Sites
Medication-related osteonecrosis of the jaw (MRONJ) is a condition that can occur in patients who take medications such as antiresorptive drugs for osteoporosis and other bone-related systemic diseases.
- Trial name
- NCT07435259
- Testing
- Implant Retention Surgery, Implant Removal Sugery
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Kyunghee University Dental Hospital
Endodontically Treated Teeth
Postoperative Pain After İntracanal Procedures
Aim: The aim of this study is to investigate the effects of different irrigation activation systems on pain after endodontic treatment in molar teeth with irreversible pulpitis.Post-operative pain values of the participants will…
- Trial name
- NCT04892355
- Testing
- Root canal irrigation
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Diabetes Mellitus Type 2 With Periodontal Disease
Using AR Dental Care Training System in HE on Periodontal Status, Blood Sugar Control and QoL in Patients With T2DM
The aim of this study was to evaluate the long-term effectiveness of an AR dental care training in health education on periodontal status, blood sugar control and quality of life in patients with poorly controlled type 2…
- Trial name
- NCT05941468
- Testing
- AR Dental Care Training System
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Dental Implants, Surface Treatment
Surface Treatment of the Dental Implant on the Osseointegration
Dental implants have become a widely accepted treatment modality for the replacement of missing single or multiple teeth in the recent years.
- Trial name
- NCT05194813
- Testing
- Aqua alvim CM, neodent implant (Test), Neoporous alvim CM, neodent implant (Control)
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Hams Hamed Abdelrahman
Periapical Periodontitis
Encapsulated Mesenchymal Stem Cells for Dental Pulp Regeneration.
To compare the dental survival in a period of one year of mature permanent teeth with apical lesion following the administration of encapsulated Mesenchymal Stem Cells under a regenerative endodontic procedure and a conventional…
- Trial name
- RanoKure (NCT03102879)
- Testing
- Regenerative Endodontic Procedure, Conventional Root Canal Treatment
- Where
- Chile
- Volunteers
- 36 people
- Sponsor
- Universidad de los Andes, Chile
Dental Infection, Clindamycin
Evaluation of an Educational Intervention on Antibiotics in Dental Care
The goal of this randomized trial is to estimate the impact of personalized prescribing portraits and educational materials on prescribing of antibiotic medications by dentists in British Columbia, Canada.
- Conditions
- Dental Infection, Clindamycin, Antibiotics
- Trial name
- NCT07016217
- Testing
- Early Plain Portrait and Letter, Early Complete Portrait and Letter, No intervention
- Where
- Canada
- Volunteers
- 3,498 people
- Sponsor
- University of British Columbia
Child Dental Anxiety
Dentapen® vs. Traditional Syringes for Child Dental Anxiety
This study aims to compare two different methods of giving local anesthesia (numbing medicine) to children during dental treatment.
- Trial name
- NCT07557160
- Testing
- Dentapen®, Traditional Dental Syringe
- Volunteers
- 42 people
- Sponsor
- Cairo University