Clinical trials: Dental Treatment
Obesity, Dental Erosion
Salivary Function and Dental Changes During GLP-1 Therapy
People who use glucagon-like peptide-1 (GLP-1) receptor agonists, such as semaglutide and tirzepatide, may experience changes in their oral health.
- Conditions
- Obesity, Dental Erosion, Saliva Collection, Saliva Altered
- Trial name
- NCT07720466
- Testing
- Unstimulated Whole Saliva Collection, Salivary Analysis, Oral Examination and BEWE Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bilecik Seyh Edebali Universitesi
Calculi
A Randomised Controlled Clinical Trial on the Use of a Dental Aerosol Box to Prevent Microbial Transmission During Dental Procedure
The study compares the use of a dental aerosol box in preventing microbial transmission during dental procedure. Subjects requiring scaling treatment (BPE 2) will be recruited.
- Trial name
- NCT05034705
- Testing
- Conventional suction system, Dental aerosol box with modified high volume evacuation system
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Pulp Necrosis, Apical Periodontitis
Comparing Amla (Emblica Officinalis) and 3% Sodium Hypochlorite Against Enterococcus Faecalis in Root Canal Treatment.
Bacteria inside the root canal are a major cause of tooth infections. If they are not completely removed, the infection may continue even after root canal treatment.
- Trial name
- NCT07688005
- Testing
- Sodium Hypochlorite 3% Solution, Emblica officinalis Solution
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Postgraduate Medical Institute, Lahore
Behavior, Child
Technological Contributions to Behavior Guidance Techniques
This study aims to evaluate the effects of three different behavior guidance methods on children's dental anxiety and pain perception.
- Conditions
- Behavior, Child, Dental Anxiety, Mobile Applications
- Trial name
- Pediatrics (NCT06912789)
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Edentulous Alveolar Ridge In Mandible, Complete Edentulism
Evaluation of Bone Changes Around Implants in Patients Treated With All on Four
The Goal of the clinical trail is to evaluate the Bone height changes around two axially placed anterior implants and two distally inclined 30-degree angle posterior implants in comparison to two axially placed anterior implants…
- Conditions
- Edentulous Alveolar Ridge In Mandible, Complete Edentulism, All on Four Technique, Dental Implant
- Trial name
- NCT06723678
- Testing
- Two distally inclined 45-degree angle posterior implants, Two distally inclined 30-degree angle posterior implants
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries
Performance of Glass-ionomer Cements: 2-year Follow-up
The purpose of this randomized clinical trial was evaluate the performance of two conventional glass-ionomer cements in the pit and fissure sealing and atraumatic restorative treatment in high caries risk children.
- Trial name
- NCT02659917
- Testing
- Glass ionomer, Glass ionomer cement, -Glass ionomer-
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Fernanda Miori Pascon
Gingivitis, Dental Plaque
Comparison Of Clinical Effects Of Listerine And Chlorhexidine Mouth Wash In Patients Undergoing Fixed Orthodontic Treatment
This randomized clinical trial aims to compare the effectiveness of Listerine and Chlorhexidine mouthwashes in improving periodontal health in patients undergoing fixed orthodontic treatment.
- Trial name
- NCT07119840
- Testing
- Listerine Mouthwash Product, Chlorhexidine mouthwash
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Phobic Disorders, Dental Anxiety
Smartphone-Based Exposure Treatment for Dental Anxiety
Exposure therapy, including its self-directed forms, is effective for treatment of specific phobias. Nevertheless, there are issues with patient adherence in the use of exposure therapy, including its self-directed formats.
- Conditions
- Phobic Disorders, Dental Anxiety, Treatment Outcome
- Trial name
- NCT03461016
- Testing
- Exposure Therapy
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Elective Primary THA or TKA
Is Routine Dental Clearance or Antibiotic Prophylaxis Before Dental Procedures Necessary in Total Joint Arthroplasty? A Randomized Controlled Noninferiority Trial
This study is a prospective, randomized, controlled, noninferiority trial with parallel assignment that will afford simultaneous assessment of the omission of dental clearance and the omission of post-operative antibiotics for…
- Trial name
- NCT07917533
- Testing
- Dental Clearance and Routine Antibiotic Prophylaxis
- Volunteers
- 3,048 people
- Sponsor
- Creighton University
Respiratory Function, Pediatric Anesthesia
Effects of Different Inspiratory:Expiratory Ratios on Respiratory and Recovery Outcomes During Dental Procedures Under General Anesthesia in Pediatric Patients
This observational study aims to evaluate the effects of different inspiratory to expiratory (I:E) ratios (1:2 vs. 1:3) during mechanical ventilation in pediatric patients undergoing dental procedures under general anesthesia.
- Conditions
- Respiratory Function, Pediatric Anesthesia, General Anesthesia
- Trial name
- NCT07323420
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Decayed Teeth
Laser Activation in Reducing Pain During and After Root Canal Treatment for Painful Lower Molar Teeth.
Effectiveness of lasers in reducing pain during and after root canal treatment for mandibular molar teeth affected with acute irreversible pulpitis.
- Trial name
- NCT04735120
- Testing
- iLASE DIODE LASERS
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CSI College of Dental Sciences and Research, Madurai
Carotid Stenosis, Mild Cognitive Impairment
Dental Carotid Cognitive Study
Periodontal Disease (PD) is present in 60+% of adults >65 years and is associated with tobacco smoking, diabetes, and atherosclerosis that worsen inflammation, comorbidities common in older people with mild to moderate cognitive…
- Conditions
- Carotid Stenosis, Mild Cognitive Impairment, Periodontitis
- Trial name
- NCT03755362
- Testing
- Standard Treatment, Intensive Treatment
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Maryland, Baltimore
Effectiveness of Microscope During Apical Surgery in Endodontic Treated Teeth.
RCT: Effectiveness of a Microscope During Dental Root Apical Surgery
An endodontic treatment is the standard therapy for teeth with periapical periodontitis. The overall success rate for this treatment is high; 97% of the treated teeth are retained in the oral cavity after 8 years (Salehrabi \&…
- Trial name
- NCT01759069
- Testing
- Surgical treatment with microscope
- Where
- Netherlands
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Tooth Extraction, Molar, Third
Efficacy of Artificial Intelligence-Generated Music Therapy in Reducing Dental Anxiety Among Adults Undergoing Impacted Third Molar Extraction
Music therapy is widely used in dentistry as it helps patients remain distracted during procedures, particularly during implant placement or third molar extraction.
- Trial name
- NCT06998979
- Testing
- Music therapy
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Coimbra
Dental Pain
Single Dose Study of N1539 in the Treatment of Pain Secondary to Dental Impaction Surgery
To evaluate the safety and efficacy of single IV doses of N1539 after dental impaction surgery.
- Trial name
- NCT00945763
- Testing
- N1539, Motrin
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Alkermes, Inc.
Dental Malocclusion
The Accuracy of Computer Software Prediction of Soft Tissue Profile for Patients Undergoing Fixed Orthodontic Treatment
A clinical study to evaluate the accuracy of computer software in predicting soft tissue profile changes in patients undergoing fixed orthodontic treatment
- Trial name
- NCT05978856
- Testing
- Accuracy of computer software in predicting soft tissue profile changes
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Focal Infection, Dental
AUGMENTIN™ in Dental Infections
In clinical practice, amoxicillin + clavulanic acid is widely used in the treatment of odontogenic infection. Therefore, this study is designed to generate data to support its use by demonstrating efficacy, safety and…
- Trial name
- AUGDENT (NCT02141217)
- Testing
- Amoxicillin/clavulanate, Clindamycin
- Where
- 15 sites in Malaysia, Philippines and 2 more
- Volunteers
- 472 people
- Sponsor
- GlaxoSmithKline
Dental Sedation, Passive Smoking
The Effects of Passive Smoking on Vital Signs, Anxiety, and Recovery Times in Children Undergoing Primary Tooth Extraction Treatment Under Sedation
The aim of this clinical study is to evaluate the effects of passive smoking on the vital parameters of children undergoing primary tooth extraction under sedation and to assess their anxiety levels throughout the process until…
- Trial name
- NCT06780189
- Testing
- Tooth Extraction and Post-Procedure Monitoring Under Sedation in Children Exposed to Passive Smoking, Tooth Extraction and Post-Procedure Monitoring Under Sedation in Children Not Exposed to Passive Smoking
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Endodontically Treated Teeth, Nonvital Teeth
Clinical Comparison of Lithium Disilicate and 3D-Printed Resin Endocrowns
This randomized controlled clinical trial aims to compare the clinical performance of CAD/CAM lithium disilicate (IPS e.max CAD) and 3D-printed resin (BEGO VarseoSmile TriniQ) endocrown restorations in endodontically treated…
- Conditions
- Endodontically Treated Teeth, Nonvital Teeth, Restoration of Endodontically Treated Posterior Teeth
- Trial name
- NCT07874906
- Testing
- IPS e.max CAD Lithium Disilicate Endocrown, BEGO VarseoSmile TriniQ Resin Endocrown
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medipol University
Endodontically Treated Teeth, Post Operative Pain
The Effect of Instrumentation and Obturation on Postoperative Pain in Retreatment
Objectives: The aim of this study was to assess postoperative pain in prospective randomized clinical trial comparing Reciproc or hand instrument and also different obturation techniques in one visit of endodontic retreatment.
- Trial name
- NCT04789343
- Testing
- Root canal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Marmara University
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