Clinical trials: Dental Treatment
Dental Caries, White Spot Lesions
QLF and Digital Imaging for Caries Activity Assessment After Orthodontic Treatment
This prospective longitudinal observational study aims to evaluate the diagnostic performance and agreement of Smartphone photography, intraoral 3D imaging, Quantitative Light-Induced Fluorescence Digital (QLF-D), and ICDAS…
- Conditions
- Dental Caries, White Spot Lesions, Caries Lesion Activity, Post-Orthodontic Enamel Demineralization
- Trial name
- NCT07608471
- Volunteers
- 30 people
- Sponsor
- Universidad El Bosque, Bogotá
Depression
Clinical Study on the Safety and Efficacy of Dental Pulp Mesenchymal Cells in the Treatment of Depression
This is a single center phase I / II clinical trial. Randomized, blind and positive drug parallel control were used to evaluate the safety and effectiveness of dental pulp mesenchymal cell injection in the treatment of depression…
- Trial name
- NCT05127369
- Testing
- Dental pulp mesenchymal cell injection, Dental pulp mesenchymal cell vehicle, fluoxetine hydrochloride capsule
- Volunteers
- 48 people
- Sponsor
- CAR-T (Shanghai) Biotechnology Co., Ltd.
Anaesthesia, Anxiety
Impact of AR Glasses on Children's Behavior During Dental Nerve Blocks
The aim of this study is to evaluate the effectiveness of augmented reality glasses in managing pain, anxiety, and behavior in pediatric patients during inferior alveolar nerve block Group A (Control group): inferior alveolar…
- Trial name
- NCT06724341
- Testing
- Distraction
- Where
- Syria
- Volunteers
- 108 people
- Sponsor
- Damascus University
Utilization of Dental Care
Measurement of Dental Health Care Utilization
measurement of utilization of dental services in pediatric department in faculty of dentistry in Cairo University within 18 month starting from January 2023 till June 2024 depending on recorded data.
- Trial name
- NCT07161362
- Where
- Egypt
- Volunteers
- 1,059 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentin Sensitivity
CPP-ACPF and Laser's Effect on Dentin Hypersensitivity
The aim of this study was to evaluate the effect of casein phosphopeptide amorphous calcium phosphate fluoride paste (CPP-ACPF) associated with low level laser therapy (LLLT) in the symptomatology and on the quality of life of…
- Trial name
- NCT03750851
- Testing
- CPPACPF, Laser, LaserCPPACPF
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Dental Fluorosis
Clinical Evaluation of Dental Fluororsis Treatment Modalities
Background: Various treatment modalities are available to improve esthetics of fluorosed teeth based on its severity. Aim: evaluate the clinical performance of different minimal invasive treatment protocols on mild to moderate…
- Trial name
- NCT05204277
- Testing
- Opalescence™ boost™ PF 40%, Opalustre™, MI-Paste Plus®
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Dental Caries, Dental Caries in Children
Atraumatic Versus Silver-Modified Atraumatic Restorative Treatment in Primary Molars
The goal of this clinical trial is to evaluate and compare the short-term effectiveness of two minimally invasive treatments-Atraumatic Restorative Treatment (ART) and Silver-Modified Atraumatic Restorative Treatment (SMART)-in…
- Trial name
- NCT07023939
- Testing
- ART: Atraumatic restorative treatment, SMART: Silver-Modified Atraumatic Restorative Treatment
- Where
- Lebanon
- Volunteers
- 34 people
- Sponsor
- Beirut Arab University
Root Canal Treated Posterior Teeth, Endodontically-Treated Teeth
Conservative Versus Conventional Restorative Approach for Endodontically Treated Posterior Teeth
This study compares two methods of restoring posterior teeth after root canal treatment. Traditionally, dentists use fiber posts and full coverage crowns, but this requires removing more tooth structure, which can weaken teeth…
- Trial name
- NCT07836920
- Testing
- Fiber reinforced composite core and an overlay, Fiber post with composite core build up and lithium disilicate full coverage crown
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Moataz Mostafa Anwar
Primary Teeth, Pulp Necrosis
Success of Lesion Sterilization and Tissue Repair Therapy
This study aimed to assess the clinical and radiographic success of lesion sterilization and tissue repair (LSTR) therapy with different antibiotic combinations, focusing on evaluating whether the alternative combination of…
- Conditions
- Primary Teeth, Pulp Necrosis, Pulpitis - Irreversible
- Trial name
- NCT06818578
- Testing
- Lesion Sterilization and Tissue Repair Therapy, Different Antibiotic Combinations
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Inonu University
Emotional Anxiety and Stress During Pediatric Dental Treatment, Dental Anesthesia
Melissa Officinalis Aromatherapy for Dental Anxiety in Children
This clinical study will look at whether a plant-based essential oil called "Melissa officinalis" (lemon balm) can help reduce fear and stress in children during dental treatment.
- Trial name
- No acronym (NCT07592130)
- Testing
- Aromatherapy with Melissa officinalis essential oil - Brand A, Aromatherapy with Melissa officinalis essential oil - Brand B, Standard behavioral management
- Volunteers
- 45 people
- Sponsor
- Universidad Autonoma de San Luis Potosí
Pulp Necrosis, Apical Periodontitis
PRP-Assisted Regenerative Endodontics Versus Conventional Root Canal Treatment in Mature Necrotic Teeth
This clinical trial will compare platelet-rich plasma (PRP)-assisted regenerative endodontic treatment with conventional root canal treatment in mature permanent teeth with pulp necrosis and apical periodontitis.
- Trial name
- NCT07918664
- Testing
- PRP-Assisted Regenerative Endodontic Treatment, Conventional Root Canal Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- TC Erciyes University
Anxiety, Behavior Management
Therapeutic Play and Music Therapy in Dental Anxiety
This study aims to evaluate the effects of therapeutic play and music therapy on dental anxiety and pain levels in pediatric patients undergoing tooth extraction.
- Conditions
- Anxiety, Behavior Management, Music Therapy
- Trial name
- NCT07112092
- Testing
- Tell-Show-Do, Music Therapy, Therapeutic Play Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Osteoporosis
Osteoporosis and Dental Implant
The purpose of this study is to evaluate the influence of alendronate therapy on the wound healing after dental implants in patients with osteoporosis.
- Trial name
- OPOZAHN (NCT00727493)
- Testing
- alendronate once weekly 70mg
- Where
- Germany
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Dental Anxiety
Anxiety Levels of Patients Subjected to Endodontic and Restorative Treatment
This study aimed to compare the stress levels induced in patients at the beginning and at the end of endodontic and restorative treatments and access relationship between dental anxiety levels and cortisol levels.
- Trial name
- NCT06764758
- Testing
- Endodontic treatment, Restorative treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Baskent University
Autism, Autism Disorders and Maternal Stress
Adapting the Sensory Environment to Reduce Stress in Children With Autism During Dental Visits
This study aims to evaluate the impact of a sensory-adapted dental environment (SADE) on the stress levels and behavioral responses of children with autism spectrum disorder (ASD) during dental visits.
- Conditions
- Autism, Autism Disorders and Maternal Stress, Sensory Integration Disorder, Stress Biomarkers
- Trial name
- SMILED (NCT07887243)
- Testing
- Sensory-Adapted Dental Environment
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Jagiellonian University
Comparison of the Effects of Propofol and Nasal Dexmedetomidine
Propofol vs. Nasal Dexmedetomidine in Pediatric Agitation and Delirium
Dental pain and anxiety are quite common in pediatric patients. However, due to children's inability to express their fears and lack of knowledge about the procedures to be performed, these symptoms have often been misunderstood…
- Trial name
- NCT06466915
- Testing
- Dexmedetomidine, Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Baskent University Ankara Hospital
Pulp Disease, Dental
Evaluation of Success Rate of Partial Pulpotomy Versus Complete Pulpotomy in Primary Molars Using NeoPUTTY MTA
Evaluating the clinical and radiographic success of partial pulpotomy compared to complete pulpotomy in vital primary second molars with reversible pulpitis using NeoPUTTY™ (MTA).
- Trial name
- NCT06524076
- Testing
- Partial Pulpotomy, Complete pulpotomy
- Volunteers
- 60 people
- Sponsor
- Cairo University
Pulpotomies Primary Teeth, Dental Pulp Disease
Comparative Evaluation of Three Different Pulpotomy Agents in Primary Molars
Comparative Evaluation of Mineral Trioxide Aggregate (MTA), Ferric Sulfate, and Chitosan Hydrogel for Primary Molar Pulpotomy: An 18-Month Randomized Controlled Trial Why is this study being done? When a child's tooth has a deep…
- Conditions
- Pulpotomies Primary Teeth, Dental Pulp Disease, Primary Teeth
- Trial name
- MTA (NCT07541976)
- Testing
- 2% Chitosan Hydrogel, MTA, Ferric Sulfate
- Where
- Iraq
- Volunteers
- 165 people
- Sponsor
- Al-Mustansiriyah University
Head and Neck Squamous Cell Carcinoma
Prospective Pilot Study Evaluating Dental Side Effects of Radiotherapy on Subjects Treated for Head and Neck Cancer
Multi-centric, one arm phase II study. The first phase of the study will consist of an evaluation of the initial dental state of each subject based on a stomatological examination, an orthopantomogram, two bitewing radiographs…
- Trial name
- StomRay (NCT04452032)
- Testing
- Dental avulsion, Radiotherapy
- Where
- 3 sites in Belgium
- Volunteers
- 40 people
- Sponsor
- Jules Bordet Institute
Dental Caries
Effect of aPDT on Deep Caries in Permanent Tooth
The aim of this study is to assess the clinical effect of aPDT on deep caries in permanent teeth. Half of the deep caries will receive aPDT disinfect in restorative treatment procedure, while the other half will receive sodium…
- Trial name
- NCT02929914
- Testing
- Local anesthesia and rubber dam isolation, Incomplete caries removal and microbiological samples collection, Dentin washed with sodium 0.9% saline
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Fujian Medical University
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