Clinical trials: Dentin Sensitivity
Medicaments Substances in Therapeutic Use
Potassium Oxalate and Potassium Nitrate and Post-bleaching Sensitivity
Objectives: This study will determine the effectiveness of the use of desensitivity gels prior in office bleaching on risk and intensity of tooth sensitivity caused by in-office bleaching using 35% hydrogen peroxide.
- Trial name
- NCT02941653
- Testing
- Potassium nitrate 2% gel, Potassium oxalate 5% gel
- Where
- Brazil
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Dentin Sensitivity
A Clinical Study to Evaluate the Anti-Sensitivity Efficacy of a Stannous Fluoride Toothpaste in a Population of Dentin Hypersensitivity Sufferers
The aim of this study is to confirm the clinical Dentin Hypersensitivity (DH) efficacy of a 0.454 percent (%) Stannous Fluoride (SnF2) toothpaste.
- Trial name
- NCT06354270
- Testing
- Stannous fluoride toothpaste, Regular fluoride toothpaste (Crest Cavity Protection)
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentine Hypersensitivity
Investigating the Efficacy of a Dentifrice in Providing Long Term Relief From Dentinal Hypersensitivity
Clinical studies have demonstrated long term relief from dentine hypersensitivity with twice daily brushing of a toothpaste containing stannous fluoride in comparison to marketed (negative) controls.
- Trial name
- NCT01827670
- Testing
- Stannous fluoride, Sodium monofluorophosphate
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentine Hypersensitivity
Single Application of Desensitizing Pastes as Dentin Sensitivity Treatment
The aim of this study was to evaluate the efficacy of three desensitizing toothpastes for immediate and intermediate-term relief of CDH, when compared with a control toothpaste.
- Trial name
- NCT02018783
- Testing
- Colgate, Sensodyne, Nano P
- Where
- Brazil
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Dentin Sensitivity
To Investigate the Efficacy of an Occluding Dentifrice in Dentinal Hypersensitivity (DH)
This single centre study will be used to investigate the efficacy of an experimental stannous fluoride containing dentifrice in relieving dentinal hypersensitivity (DH) after short term use compared with a standard fluoride…
- Trial name
- NCT02923895
- Testing
- Stannous fluoride, Sodium monofluorophosphate
- Where
- Canada
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity
Investigating the Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity
This single center, comparative design study will be used to investigate the efficacy of an experimental stannous fluoride containing dentifrice in relieving dentinal hypersensitivity (DH) after short term use compared with a…
- Trial name
- NCT02832375
- Testing
- stannous fluoride, sodium monofluorophosphate
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Hypersensitivity
Effect of Chemical and Light Bleaching Techniques on Color Change, Dentin Hypersensitivity and Patient Satisfaction
Aim of The Study This study aims is to evaluate color change, dentin hypersensitivity and patient satisfaction after different bleaching techniques at different time intervals.
- Trial name
- NCT07669324
- Testing
- Light activated bleaching, Chemically activated bleaching
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nahda University
Dentin Sensitivity
Effectiveness of Two Water-Based Potassium Oxalate Desensitizers
This study will compare the safety and effectiveness of two water-based potassium oxalate desensitizers on existing dentinal hypersensitivity.
- Trial name
- NCT02192307
- Testing
- Potassium oxalate
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Tooth Sensitivity
Evaluation of Sensitivity and Color Change of Different Protocols of In-office Dental Bleaching
Clinical randomized single-blind trial, used to measure the level of tooth sensitivity (TS) after in-office dental bleaching sessions, on volunteers using a modified visual analog scale (VAS).
- Trial name
- NCT07597044
- Testing
- Standard in-office tooth bleaching, Alternative in-office tooth bleaching
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Dentin Sensitivity
Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Dentinal Hypersensitivity
This study will investigate the longitudinal efficacy of two experimental oral rinses containing 1.5% weight/weight (w/w) dipotassium oxalate monohydride (KOX), formulated at pH 4.5 and pH 7 respectively, for the relief of…
- Trial name
- NCT02542943
- Testing
- Experimental Oral Rinse 1, Experimental Oral Rinse 2, Standard fluoride toothpaste
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Tooth Discoloration
Clinical Efficacy of In-office Bleaching With Different Concentrations of Hydrogen Peroxide
Objective: The study evaluated the longevity, effectiveness, sensitivity and impact on the oral health-related quality of life of in-office dental bleaching using low, medium, and high concentrate hydrogen peroxide.
- Trial name
- NCT06700434
- Testing
- Bleaching treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gazi University
Dentin Hypersensitivity
Effectiveness of Calcium Silicate and Sodium Fluoride Nanoparticles in The Management of Dentin Hypersensitivity
This study will be performed to assess the effect of inert prepared tooth paste loaded with Calcium Silicate Nanoparticles (CSNPs) and compare it to another one containing Sodium Fluoride Nanoparticles in the management of…
- Trial name
- NCT06557980
- Testing
- toothpaste
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Tooth Discoloration, Dentin Sensitivity
Efficacy and Safety Assessment of Experimental Bleaching Agents
Tooth bleaching is widely used to treat the colors of teeth. This study compares the efficiency of two experimental bleaching gels, with and without nanoparticles, and with and without light activation versus two commercial…
- Conditions
- Tooth Discoloration, Dentin Sensitivity, Patient Satisfaction
- Trial name
- NCT06802614
- Testing
- BLEACHING GEL A, 5% NF_TiO2, BLEACHING GEL B
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Dentin Sensitivity
A Clinical Study Assessing the Effects of a Marketed Dentifrice on Tooth Sensitivity While Undergoing Tooth Bleaching
The aim of this study is to investigate the efficacy of a marketed dentifrice containing 5 percent (%) NovaMin (Calcium Sodium Phosphosilicate) to reduce tooth sensitivity during and post tooth bleaching compared to a marketed…
- Trial name
- NCT06608368
- Testing
- Test Dentifrice (Sensodyne Repair and Protect Original Mint), Positive Control Dentifrice (Sensodyne Fresh Mint), Reference Dentifrice (Crest Cavity Protection Regular)
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Sensitivity, Hypersensitivity
A Clinical Trial to Compare Lasotronix Alone or in Combination With CPP-ACP to Treat DH
Dentin hypersensitivity (DH) is defined as sharp pain of a shorter duration arise from exposed dentin in response to several chemicals and thermal or tactile stimuli that cannot be ascribed to other dental defects".
- Conditions
- Dentin Sensitivity, Hypersensitivity, Cervical Lesion
- Trial name
- NCT06463938
- Testing
- Active comparator, Experimental group, Combination of laser and paste
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Sensitivity, Tooth
Dentinal Hypersensitivity Reduction Efficacy Study
Assess the clinical efficacy of CSPR Toothpaste containing 8% arginine to provide dentinal hypersensitivity relief
- Trial name
- NCT06960148
- Testing
- CSPR Toothpaste, Colgate Dental Cream Toothpaste
- Where
- China
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dentin Sensitivity
A Study to Evaluate the Safety and Efficacy of an Oxalate Strip on Adjacent Teeth With Dentinal Hypersensitivity
This study will compare the safety and effectiveness of a potassium oxalate desensitizer on adjacent teeth with dentinal hypersensitivity.
- Trial name
- NCT02293044
- Testing
- Crest® Sensi-Stop™ Strips
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Dentine Hypersensitivity
Neurological Responses in Patients with Dentine Hypersensitivity
Dentine hypersensitivity (also known as sensitive teeth) is a common dental condition in which the dentine, a layer of sensitive hard tissue under the enamel of the teeth, becomes exposed making the teeth sensitive to stimuli…
- Trial name
- NCT06633627
- Testing
- Recording of brain activity using electroencephalography (EEG)
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Dentin Sensitivity
Effects of an Oxalate Containing Product on Dentinal Hypersensitivity With Dental Prophylaxis
This study will assess sensitivity during a dental prophylaxis with or without the use of a potassium oxalate salt solution.
- Trial name
- NCT02481557
- Testing
- Oxalate Salt Solution
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Dentin Sensitivity
A Study to Investigate Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Pain Derived From Exposed Dentine in Response to Chemical, Thermal, Tactile, or Osmotic Stimuli.
This will be a single center, eight week, randomized, double blind, three treatment arm, parallel design, stratified (by mean baseline Schiff Sensitivity Score of the two selected test teeth) study in healthy participants.
- Trial name
- NCT02651467
- Testing
- Experimental Oral Rinse 1 (1.5% w/w KOX, 0ppm F, pH 7.0), Experimental Oral Rinse 2 (2.0% w/w KOX, 45ppm F, pH 4.5)
- Where
- United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline