Clinical trials: Dentine Hypersensitivity
Dentine Hypersensitivity
The Efficacy of a Dentifrice in Providing Relief From the Pain of Dentinal Hypersensitivity
A study to compare the efficacy of a test dentifrice against a control dentifrice in reducing dentinal hypersensitivity over an eight week treatment period.
- Trial name
- NCT01592864
- Testing
- Stannous Fluoride, Sodium Monofluorophosphate
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity
A Test on a New Experimental Mouth Rinse for Relieving Tooth Sensitivity
This study is for people with sensitive teeth and involves going to the dentist for 4 visits over 6 weeks. At each visit the dentist will look at the mouth, teeth, tongue and gums of subjects, and check for sensitive teeth.
- Trial name
- NCT01727258
- Testing
- Mouth Rinse, Fluoride Toothpaste, Potassium Nitrate Toothpaste
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Dentine Hypersensitivity
The Efficacy of a Dentifrice in Providing Relief From Immediate and Short Term Relief From Dentinal Hypersensitivity
A randomised, examiner blind, two treatment arm, stratified, parallel design, single-site study in subjects with at least two sensitive teeth to compare the efficacy of a test dentifrice against that of a control dentifrice in…
- Trial name
- NCT03072719
- Testing
- Stannous Fluoride, Sodium Monofluorophosphate
- Where
- Ireland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity
Clinical Study to Evaluate the Anti-sensitivity Efficacy of a Stannous Fluoride Toothpaste in a Population of Dentin Hypersensitivity Sufferers
The aim of this study is to confirm the clinical Dentin Hypersensitivity (DH) efficacy of a 0.454 percent (%) Stannous Fluoride (SnF2) toothpaste.
- Trial name
- NCT06359028
- Testing
- Stannous fluoride toothpaste, Crest cavity protection toothpaste
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentine Hypersensitivity
Instant and Lasting Relief Effects of Strontium Chloride/Potassium Nitrate Dentifrice on Dentin Hypersensitivity
The objective of the present study was to compare the effects of a commercially available dentifrice containing 2% strontium chloride and 5% potassium nitrate in a silica base, versus a control dentifrice, containing exactly the…
- Trial name
- NCT01426360
- Testing
- control dentifrice, strontium chloride/potassium nitrate dentifrice
- Where
- China
- Volunteers
- 79 people
- Sponsor
- Sun Yat-sen University
Dentin Sensitivity
A Study in Dentinal Hypersensitivity (DH) Participants to Assess the Efficacy of an Occluding Dentifrice.
This study will investigate the longitudinal efficacy of two experimental oral rinses, one containing 1.5% weight/weight (w/w) dipotassium oxalate monohydride (KOX) /0 Parts per Million (ppm fluoride) and the other 2.0% w/w KOX…
- Trial name
- NCT02753075
- Testing
- Experimental Oral Rinse 1, Experimental Oral Rinse 2, Fluoride toothpaste
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity
Test on a New Experimental Mouth Rinse for Relieving Tooth Sensitivity
This study is for people with sensitive teeth and involves going to the dentist for 4 visits over 6 weeks. At each visit the dentist will look at the mouth, teeth, tongue and gums of participants, and check for sensitive teeth.
- Trial name
- NCT02113579
- Testing
- Experimental Mouth Rinse 12027-033
- Where
- 2 sites in United States
- Volunteers
- 375 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Dentin Sensitivity
Assessment of the Efficacy of an Experimental Occlusion Technology Dentifrice in Dentinal Hypersensitivity
This study will evaluate the effectiveness of an experimental dentifrice containing stannous fluoride, an established dentine tubule occlusion technology, at reducing dentine hypersensitivity (DH) compared to a negative control…
- Trial name
- NCT02861664
- Testing
- Stannous fluoride (SnF2), Sodium monofluorophosphate (SMFP)
- Where
- China
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Tooth Hypersensitivity
NUPRO Sensodyne Prophylaxis Paste With NovaMin Sensitivity Relief Study
The study is intended to verify through clinical measurement that the NUPRO Sensodyne Prophylaxis Paste with Novamin provides immediate sensitivity relief as well as extended relief up to 28 days.
- Trial name
- NCT01669785
- Testing
- Group C, Group A, Group B
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Dentsply International
Dentin Sensitivity
A Clinical Study to Evaluate the Anti-Sensitivity Effect of a Calcium Sodium Phosphosilicate Toothpaste in a Population of Dentin Hypersensitivity Sufferers
The aim of this study is to confirm the clinical dentin hypersensitivity (DH) efficacy of a 5 percent (%) calcium sodium phosphosilicate (CSPS) toothpaste.
- Trial name
- NCT06378008
- Testing
- CSPS toothpaste, Regular fluoride toothpaste (Crest Cavity Protection)
- Where
- Canada
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Sensitivity
Impact of Long Term Management of Dentine Hypersensitivity (DH) With a Daily Use Anti-sensitivity Toothpaste on the Quality of Life Related to Oral Health
This multicentre, non-comparative design study will monitor the impact of long term management of DH with daily use of a sensitivity toothpaste on the quality of life of a population of sensitivity sufferers.
- Trial name
- NCT02752958
- Testing
- stannous fluoride
- Where
- 2 sites in United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity
A Study to Assess Efficacy of an Experimental Oral Rinse in Providing Long Term Relief From Dentinal Hypersensitivity
To investigate the efficacy of an experimental oral rinse, containing 1.5% potassium oxalate (KOX) and 0 parts per million (ppm) fluoride in relieving dentine hypersensitivity (DH) after 8 weeks use compared with a placebo oral…
- Trial name
- NCT03238352
- Testing
- Potassium oxalate, Sodium fluoride
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity
The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity(DH)
This single centre, comparative design study will be used to investigate the efficacy of an experimental stannous fluoride containing dentifrice in relieving dentinal hypersensitivity (DH) after short term use compared with a…
- Trial name
- NCT02751450
- Testing
- Stannous Fluoride dentifice, Sodium Monofluorophosphate dentifrice
- Where
- United Kingdom
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity
A Pilot Clinical Study to Evaluate the Safety and Efficacy of Marketed Oxalate Strips Compared to a Marketed Safety Pen
This pilot study will evaluate the safety and effectiveness of a marketed sensitivity strip on existing dentinal hypersensitivity compared to a marketed sensitivity pen.
- Trial name
- NCT02384044
- Testing
- Crest® Sensi-Stop™ Strips, Colgate® Sensitivity Relief Pen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Dentin Sensitivity
A Study to Evaluate the Safety and Efficacy of an Oxalate Strip on Adjacent Teeth With Dentinal Hypersensitivity
This study will compare the safety and effectiveness of a potassium oxalate desensitizer on adjacent teeth with dentinal hypersensitivity.
- Trial name
- NCT02293044
- Testing
- Crest® Sensi-Stop™ Strips
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Dentin Sensitivity
Trial of Nano-hydroxyapatite-Containing Toothpastes for Relief of Dentin Hypersensitivity
Subjects will be enrolled into 3 balanced groups each using a different strength toothpaste. Dental hypersensitivity (DHS) will be assessed at study start, midway and study end.
- Trial name
- NCT04590040
- Testing
- 15% nano-HAP toothpaste, 5% KNO3 toothpaste
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Dentine Hypersensitivity, Dental Pain
Dose Response of a Tubule Occlusion Agent
To evaluate the efficacy of two different concentrations of a tubule occlusion agent - calcium sodium phosphosilicate in treatment of dentine hypersensitivity
- Trial name
- NCT01075256
- Testing
- 5% calcium sodium phosphosilicate toothpaste, 7.5% calcium sodium phosphosilicate toothpaste
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- GlaxoSmithKline
Dentin Hypersensitivity
Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH
This will be multi-centered, triple blinded, randomized, four parallel treatments assigned study to compare clinical efficacy of commercially available dentifrices with placebo for immediate and sustained relief from Dentin…
- Trial name
- NCT04249336
- Testing
- Fluoro-Calcium-Phospho-Silicate based dentifrices, 8% Arginine based dentifrices, 8% Strontium Acetate
- Where
- Pakistan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Dentin Sensitivity
A Clinical Study to Evaluate the Efficacy of a Stannous Fluoride Dentifrice in the Relief of Dentinal Hypersensitivity in a Chinese Population
The purpose of this study is to support long-term dentinal hypersensitivity (DH) relief claims of 0.454 percent (%) stannous fluoride (SnF2) containing toothpastes in China.
- Trial name
- NCT04950465
- Testing
- Sensodyne Sensitivity & Gum, Crest Cavity Protection Fresh Lime, Sensodyne Repair and Protect
- Where
- China
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Sensitivity
Effectiveness of Two Water-Based Potassium Oxalate Desensitizers on Dental Hypersensitivity
This study will compare the safety and effectiveness of two water-based potassium oxalate desensitizers on existing dentinal hypersensitivity.
- Trial name
- NCT02152826
- Testing
- Potassium oxalate
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble