Clinical trials: Dentofacial Deformities
Dentofacial Deformity
Orthognathic Surgery and Postoperative Antibiotic Use
Currently there is debate in the literature as to the recommended length of postoperative antibiotics in patients undergoing orthognathic surgery.
- Trial name
- NCT01823523
- Testing
- Cefazolin, Cephalexin, Clindamycin
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Atlantic Center for Oral and Maxillofacial Surgery
Dentofacial Deformities, Regional Anesthesia Morbidity
Ultrasound-guided Bilateral Suprazygomatic Maxillary Nerve Block and Bimaxillary Osteotomy
Bimaxillary osteotomy is a surgery procedure of the orthognathic surgery field with the aim to correct dental and facial abnormalities, for both functional and aesthetic cases.
- Trial name
- NCT03913429
- Testing
- Infiltration, Maxillary nerve blockade
- Where
- Spain
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Servei Central d'Anestesiologia
Dentofacial Deformities
Evaluating the Relationship Between Hard and Soft Tissue Advancement in Orthognathic Surgery
This study aims to evaluate the relationship between hard and soft tissue advancement during orthognathic surgery. The use of typical pre and post operative imaging consisting of con-beam computed tomography will be used, in…
- Trial name
- NCT03652155
- Testing
- Orthognathic surgery
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Nova Scotia Health Authority
Orthognathic Surgery, Dentofacial Deformities
Development and Validation of an Automated Three-dimensional Cephalometry Method
This study is aimed to develop and assess the validity of an algorithm for automated three-dimensional cephalometry.
- Trial name
- AutoCEPH-3D (NCT04464252)
- Where
- France
- Volunteers
- 453 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dentofacial Deformities
Skeletal Stability of Le Fort I Osteotomy Using Patient-specific Osteosynthesis Compared to Mini-plate Fixation for Patients With Dentofacial Disharmony
The aim of the study is to evaluate the Skeletal stability of Le Fort I osteotomy using patient-specific osteosynthesis compared to Mini-plate fixation for patients with skeletal class III malocclusion.
- Trial name
- NCT05340036
- Testing
- Bimaxillary orthognathic surgery using conventional plates, Bimaxillary orthognathic surgery using patient specific plates
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Hassan Fahmy Hassan Alnimr
Head and Neck Cancer, Radiotherapy Side Effect
DENTOFACIAL-PBT Stage 2 - Feasibility Study
What is the health problem? Proton beam therapy (PBT), a type of radiotherapy treatment, can be especially beneficial to children and teenagers with cancer.
- Conditions
- Head and Neck Cancer, Radiotherapy Side Effect, Adverse Effect of Radiation Therapy, Childhood Cancer
- Trial name
- NCT07057284
- Testing
- Orthopantomogram (or a set of Lateral Oblique Radiographs)
- Where
- 2 sites in United Kingdom
- Volunteers
- 255 people
- Sponsor
- Manchester University NHS Foundation Trust
Mandibular Neoplasms, Maxillary Neoplasms
Three-Dimensional Printing of Patient-Specific Titanium Plates in Jaw Surgery: A Pilot Study
Medical titanium plates are routinely used in fixing mobilized bone segments in jaw surgeries. Generally these plates are commercialized with standard construction specifications.
- Conditions
- Mandibular Neoplasms, Maxillary Neoplasms, Dentofacial Deformities, Maxillofacial Injuries
- Trial name
- 3DJP16 (NCT03057223)
- Testing
- 3D-printed patient-specific titanium plates
- Where
- Hong Kong
- Volunteers
- 96 people
- Sponsor
- The University of Hong Kong
Maxillary Anomaly, Asymmetric Maxillary Arch (Disorder)
Effects of Asymmetric Rapid Maxillary Expansion on Dentoskeletal Structures in Mixed Dentition
The aim of this clinical trial was to determine the efficacy of a locked modified bonded acrylic rapid maxillary expansion appliance, also known as an asymmetric rapid maxillary expansion appliance (ARME), in patients with a true…
- Conditions
- Maxillary Anomaly, Asymmetric Maxillary Arch (Disorder), Cross Bite
- Trial name
- ARME (NCT06486324)
- Testing
- A locked modified acrylic bonded rapid maxillary expansion appliance (ARME)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Celal Irgin
Skeletal Class II Malocclusion, Skeletal Class III Malocclusion
Clinical and Radiographic Evaluation of Low Sagittal Medial Ramus Osteotomy for Treatment of Skeletal Class II and Class III Malocclusion
This prospective clinical trial aims to evaluate the clinical and radiographic outcomes of the low sagittal medial ramus osteotomy-a technical modification of the conventional sagittal split osteotomy (SSO)-for treating patients…
- Conditions
- Skeletal Class II Malocclusion, Skeletal Class III Malocclusion, Dentofacial Deformities
- Trial name
- NCT07746700
- Testing
- Low Sagittal Medial Ramus Osteotomy
- Volunteers
- 11 people
- Sponsor
- Al-Azhar University
Dentofacial Deformities
Full-3D Computer-Assisted Workflow for the Diagnosis and Correction of Deformities? Dentofacial
"Dentofacial deformity refers to deviations from the norm of facial proportions and tooth ratios of such magnitude as to represent a disability." [1] These conditions afflicted two aspects of the patient's health: the first…
- Trial name
- NCT06806605
- Testing
- 3d analisys
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Dentofacial Deformities, Orthognathic Surgery
Quantitative Evaluation of Attention to Faces After Orthognathic Surgery With Eye-tracking
Dentofacial deformities refer to morphological anomalies of the jaws. Their development during growth determines the shape of the lower third of the face and the type of dental occlusion.
- Conditions
- Dentofacial Deformities, Orthognathic Surgery, Social Perception, Eye Tracking
- Trial name
- OCHIRO (NCT06494709)
- Testing
- photographs
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Maxillary Deficiency
Comparative Results of Maxillary Deficiency Treatment by Tongue Plate and Facemask in Growing Patients
A new appliance will be used to transfer the tongue force during its physiological activity to advance the nasomaxillary complex; this method will be compared with the traditional method which uses a Facemask appliance.
- Trial name
- NCT00519415
- Testing
- Tongue plate, Facemask
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Orthognathic Surgery, Malocclusions
Evaluation of Emotional Responses Using the I-Motions System and Self-assessment Questionnaires, and Assessment of Postoperative Anatomical and Structural Units (TMJ and Masticatory Muscles) in Orthognathic Surgery Patients
Orthognathic surgery is a surgical procedure involving one or both jaws to correct skeletal discrepancies, restore proper occlusion, and improve facial aesthetics.
- Conditions
- Orthognathic Surgery, Malocclusions, Jaw Abnormalities, Dentofacial Deformities
- Trial name
- NCT07477873
- Testing
- Observational Assessment
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Lithuanian University of Health Sciences
Mandibular Neoplasms, Maxillary Neoplasms
3D-Printed Patient-Specific Surgical Plates Versus Conventional Surgical Plates in Jaw Reconstruction
Objectives: The aim of this randomised controlled clinical trial is to evaluate surgical accuracy and efficiency of computer-assisted jaw reconstruction using 3D-printed patient-specific titanium surgical plates versus…
- Conditions
- Mandibular Neoplasms, Maxillary Neoplasms, Dentofacial Deformities
- Trial name
- NCT04635865
- Testing
- 3D-printed patient-specific plate, Conventional commercial reconstruction plate
- Where
- Hong Kong
- Volunteers
- 92 people
- Sponsor
- The University of Hong Kong
Dentofacial Deformities, Dentofacial Anomalies [Including Malocclusion] and Other Disorders of Jaw (M26-M27)
Effect of Proximal Segment Positioning on Postoperative Condylar Remodeling in Bimaxillary Orthognathic Surgery
Bimaxillary orthognathic surgery is a surgical procedure that involves simultaneous corrections to both the maxilla (upper jaw) and mandible (lower jaw).
- Trial name
- NCT06897787
- Testing
- manuel positioning group, mandibular basis osteotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Dentofacial Deformities
3D Photogrammetry Versus Commercial Scanners for Accurate Repositioning of the Maxilla for Correction of the Dentofacial Deformity.
Current advances in the three-dimensional virtual surgical planning (3D-VSP) of the orthognathic surgery have brought newer insights, enormous benefits and have become an indispensable aid for diagnosis, treatment planning and…
- Trial name
- NCT05755022
- Testing
- Maxillary Segment Repositioning
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentofacial Deformities, Malocclusions
Changes in Depression and Esthetic Perception After Orthognathic Surgery
This study aims to evaluate changes in depressive symptoms and subjective esthetic perception before and after bimaxillary orthognathic surgery in patients with different types of malocclusion.
- Conditions
- Dentofacial Deformities, Malocclusions, Orthognathic Surgery
- Trial name
- NCT07702448
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Kırıkkale University
Dentofacial Deformities, Edema
Lymphatic Drainage Massage and Melatonin in Post-Orthognathic Surgery Pain and Edema
Lymphatic drainage massage is one of the most essential techniques for reducing edema. It is a very gentle, monotonous, slow, rhythmic massage applied to the skin's surface.
- Conditions
- Dentofacial Deformities, Edema, Pain
- Trial name
- NCT07062757
- Testing
- no intervention, lymphatic drainage massage, oral melatonin tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Dentofacial Deformities
Effects of Oral Melatonin on Neurosensory Recovery Following Facial Osteotomies
Orthognathic surgery is commonly performed for the treatment of dentofacial deformities. Yet, one of the most prevalent and long-term complication encountered is neurosensory disturbance thus impairing sensation to parts of the…
- Trial name
- NCT02889432
- Testing
- Oral Melatonin 10mg
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Dentofacial Deformities
Preoperative Anxiety and Its Impact on Intraoperative Hemodynamics and Postoperative Pain, Edema, and Trismus in Orthognathic Surgery
This study aims to investigate the relationship between preoperative anxiety and intraoperative hemodynamic changes, as well as postoperative pain and facial edema, in patients undergoing orthognathic surgery.
- Trial name
- NCT07439679
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul Medipol University Hospital