Clinical trials: Dentofacial Deformity, open to volunteers
Obstructive Sleep Apnea, Sleep Apnea, Obstructive
Orthognathic Surgery and Obstructive Sleep Apnea Assessed by Mandibular Jaw Movement Monitoring (SUNRISE-ORTHO)
Orthognathic surgery changes the skeletal framework of the upper airway, but its functional effect on sleep-disordered breathing remains poorly documented, particularly with respect to respiratory effort.
- Conditions
- Obstructive Sleep Apnea, Sleep Apnea, Obstructive, Dentofacial Deformities
- Trial name
- SUNRISE-ORTHO (NCT07910461)
- Testing
- Orthognathic surgery (BSSO with or without Le Fort I osteotomy), Sunrise mandibular jaw movement monitoring, Facial multidetector CT in natural head position
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- CHR Sambre et Meuse Site Meuse
Prognathism, Retrognathism
Natural History of Craniofacial Anomalies and Developmental Growth Variants
Background: Some head and facial abnormalities are rare and present at birth. Others are more common, and may not show up until puberty. These conditions have different causes and characteristics.
- Conditions
- Prognathism, Retrognathism, Dentofacial Deformities
- Trial name
- NCT02639312
- Where
- United States
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Malocclusion, Angle Class II, Malocclusion, Angle Class III
Comparing 3D-Printed and Milled Titanium Plates in Jaw Surgery (Le Fort I): Accuracy and Operative Time
The purpose of this study is to find out if 3D printed patient-specific titanium plates improve surgical accuracy and decrease operative time compared to milled patient-specific titanium plates in patients having Le Fort I…
- Conditions
- Malocclusion, Angle Class II, Malocclusion, Angle Class III, Dentofacial Deformities, Osteotomy, Le Fort I
- Trial name
- TiPlateRCT (NCT07841067)
- Testing
- 3D-Printed Patient-Specific Titanium Plates, Milled Patient-Specific Titanium Plates
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Future University in Egypt
Dentofacial Deformities, Orthognathic Surgery
Quantitative Evaluation of Attention to Faces After Orthognathic Surgery With Eye-tracking
Dentofacial deformities refer to morphological anomalies of the jaws. Their development during growth determines the shape of the lower third of the face and the type of dental occlusion.
- Conditions
- Dentofacial Deformities, Orthognathic Surgery, Social Perception, Eye Tracking
- Trial name
- OCHIRO (NCT06494709)
- Testing
- photographs
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Skeletal Class II Malocclusion, Skeletal Class III Malocclusion
Clinical and Radiographic Evaluation of Low Sagittal Medial Ramus Osteotomy for Treatment of Skeletal Class II and Class III Malocclusion
This prospective clinical trial aims to evaluate the clinical and radiographic outcomes of the low sagittal medial ramus osteotomy-a technical modification of the conventional sagittal split osteotomy (SSO)-for treating patients…
- Conditions
- Skeletal Class II Malocclusion, Skeletal Class III Malocclusion, Dentofacial Deformities
- Trial name
- NCT07746700
- Testing
- Low Sagittal Medial Ramus Osteotomy
- Volunteers
- 11 people
- Sponsor
- Al-Azhar University
Dentofacial Deformities, Malocclusions
Changes in Depression and Esthetic Perception After Orthognathic Surgery
This study aims to evaluate changes in depressive symptoms and subjective esthetic perception before and after bimaxillary orthognathic surgery in patients with different types of malocclusion.
- Conditions
- Dentofacial Deformities, Malocclusions, Orthognathic Surgery
- Trial name
- NCT07702448
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Kırıkkale University
Dentofacial Abnormalities, Dentofacial Deformities
Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses
The investigators are studying how speech is effected by jaw and tooth position in jaw surgery patients. Eighty percent of our jaw surgery patients have speech pathologies, compared to five percent of the general population, but…
- Conditions
- Dentofacial Abnormalities, Dentofacial Deformities, Dentofacial Anomalies, Including Malocclusion, Malocclusion
- Trial name
- OSP (NCT04117360)
- Testing
- Orthognathic surgery and Orthodontics
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of North Carolina, Chapel Hill
Malocclusion, Craniofacial Morphology
Research on Deep Learning-Based Intelligent Diagnosis and Treatment
This study aims to develop and evaluate deep learning-based artificial intelligence models for craniomaxillofacial multi-modal imaging analysis and clinical decision support.
- Conditions
- Malocclusion, Craniofacial Morphology, Dentofacial Deformities
- Trial name
- NCT07551622
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Xi'an Jiaotong University
Orthognathic Surgery, Malocclusions
Evaluation of Emotional Responses Using the I-Motions System and Self-assessment Questionnaires, and Assessment of Postoperative Anatomical and Structural Units (TMJ and Masticatory Muscles) in Orthognathic Surgery Patients
Orthognathic surgery is a surgical procedure involving one or both jaws to correct skeletal discrepancies, restore proper occlusion, and improve facial aesthetics.
- Conditions
- Orthognathic Surgery, Malocclusions, Jaw Abnormalities, Dentofacial Deformities
- Trial name
- NCT07477873
- Testing
- Observational Assessment
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Lithuanian University of Health Sciences
Dentofacial Deformities
Preoperative Anxiety and Its Impact on Intraoperative Hemodynamics and Postoperative Pain, Edema, and Trismus in Orthognathic Surgery
This study aims to investigate the relationship between preoperative anxiety and intraoperative hemodynamic changes, as well as postoperative pain and facial edema, in patients undergoing orthognathic surgery.
- Trial name
- NCT07439679
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul Medipol University Hospital
Dentofacial Deformities
Patient-Specific vs. Conventional Positioning in Sagittal Split Ramus Osteotomy
This study aims to evaluate the clinical efficacy and positioning accuracy of a custom-made proximal segment positioning appliance designed for use in sagittal split ramus osteotomy (SSRO).
- Trial name
- NCT07125963
- Testing
- Custom-made positioning appliance-assisted mandibular segment repositioning, Conventional Manual Positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Sümer Münevveroğlu
Dentofacial Deformities, Edema
Lymphatic Drainage Massage and Melatonin in Post-Orthognathic Surgery Pain and Edema
Lymphatic drainage massage is one of the most essential techniques for reducing edema. It is a very gentle, monotonous, slow, rhythmic massage applied to the skin's surface.
- Conditions
- Dentofacial Deformities, Edema, Pain
- Trial name
- NCT07062757
- Testing
- no intervention, lymphatic drainage massage, oral melatonin tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Dentofacial Deformities, Dentofacial Anomalies [Including Malocclusion] and Other Disorders of Jaw (M26-M27)
Effect of Proximal Segment Positioning on Postoperative Condylar Remodeling in Bimaxillary Orthognathic Surgery
Bimaxillary orthognathic surgery is a surgical procedure that involves simultaneous corrections to both the maxilla (upper jaw) and mandible (lower jaw).
- Trial name
- NCT06897787
- Testing
- manuel positioning group, mandibular basis osteotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Dentofacial Deformities
Full-3D Computer-Assisted Workflow for the Diagnosis and Correction of Deformities? Dentofacial
"Dentofacial deformity refers to deviations from the norm of facial proportions and tooth ratios of such magnitude as to represent a disability." [1] These conditions afflicted two aspects of the patient's health: the first…
- Trial name
- NCT06806605
- Testing
- 3d analisys
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna