Clinical trials: Depressed
Depression
Magnesium Sulfate Versus 5% Dextrose With Treatment Resistant Depression
The proposed study is a 1-week, randomized, double-blind, placebo-controlled, trial to evaluate the efficacy of an IV infusion of magnesium sulfate on symptoms of treatment resistant mild and moderate depression in 20 males and…
- Trial name
- NCT01597167
- Testing
- Magnesium sulfate
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Miami
Menopause, Insomnia
The Treatment of Insomnia in Symptomatic Peri- and Postmenopausal Women
To examine the change in sleep patterns and mood symptoms in response to eszopiclone (Lunesta) using a double-blind placebo-controlled cross-over study design in perimenopausal and postmenopausal women who experience insomnia…
- Trial name
- NCT00374192
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Major Depressive Disorder
A Comparison of Cognitive and Dynamic Therapy for Depression in Community Settings
The goal of this study is to compare supportive-expressive therapy, a type of psychodynamic psychotherapy, with cognitive therapy for the treatment of depression in community mental health consumers.
- Trial name
- NCT01207271
- Testing
- Cognitive Therapy, Supportive-Expressive Psychodynamic Therapy
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- University of Pennsylvania
Schizophrenia, Major Depression
Procedures for Sample Acquisition and Distribution for The Human Brain Collection Core
Background: The Human Brain Collection Core (HBCC) collects brain and other tissues. They get these from deceased people who may or may not have had psychiatric disorders.
- Conditions
- Schizophrenia, Major Depression, Bipolar Disorder, PTSD
- Trial name
- NCT03092687
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- National Institute of Mental Health (NIMH)
Depression
Personalized Depression Treatment Supported by Mobile Sensor Analytics
The current best practice guidelines for treating depression call for close monitoring of patients, and periodically adjusting treatment as needed.
- Trial name
- DepWatch (NCT06292221)
- Testing
- A mobile Health (mHealth) tool called 'DepWatch'
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- UConn Health
Sleep Deprivation, Gut Microbiota
Microbiota Profiles in Newly Married Couples: Potential Effects on Vision, Sleep and Psychometric Parameters
Oral, fecal and conjunctival samples will be collected from participants and will be stored (at - 20 and - 80 ◦C) until further processing.
- Conditions
- Sleep Deprivation, Gut Microbiota, Optometry Examinations, Oral Microbiota
- Trial name
- NCT06638606
- Testing
- Sleep improvement techniques
- Where
- Iran
- Volunteers
- 1,740 people, healthy volunteers welcome
- Sponsor
- Reza Rastmanesh
Depression, Treatment Resistant Depression
Mindfulness Engaged Neurostimulation for Depression (MEND II)
Repetitive Transcranial Magnetic stimulation (rTMS) is an FDA-approved therapy for treatment resistant depression (TRD) that involves brief magnetic stimulation pulses on the dorsolateral prefrontal cortex (DLPFC) brain region.
- Conditions
- Depression, Treatment Resistant Depression, Major Depressive Disorder, Depressive Disorder
- Trial name
- NCT07512284
- Testing
- Medi-TBS
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, San Diego
Depression, Neurofeedback
Neurofeedback In Treatment Resistant Depression
The investigators evaluate the effects of neurofeedback as an augmentation treatment on depressive symptoms and functional recovery in patients with treatment-resistant depression (TRD).
- Trial name
- NCT04078438
- Testing
- neurofeedback augmentation, treatment as usual
- Where
- South Korea
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Yeungnam University Hospital
Anxiety, Depression - Major Depressive Disorder
Integrative Group Psychotherapy (Terebenin's Method) in Adults With Subclinical and Mild/Moderate Anxiety and Depression
Title Pilot Randomized Controlled Trial of an Integrative Group Psychotherapy (Terebenin's Method) in Adults with Subclinical and Mild/Moderate Anxiety and Depression Summary and Detailed Description (Single Text Block) Anxiety…
- Trial name
- NCT06863948
- Testing
- Teribenin method, Control Interventions
- Where
- Russia
- Volunteers
- 66 people
- Sponsor
- S.LAB (SOLOWAYS)
Depression, Postpartum, Anxiety
eMBC for Perinatal Depression and Anxiety
Depression and anxiety that occur around the time of pregnancy can adversely impact a person's health and well-being, and their child's health and development.
- Trial name
- eMBC (NCT04836585)
- Testing
- eMBC Intervention
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Women's College Hospital
Psychological Resilience Among Midwives Working in Delivery Rooms
Mandala Coloring and Resilience in Midwives
Midwives working in delivery rooms are exposed to occupational and psychological stressors associated with high workloads, shift work, time pressure, obstetric emergencies, and traumatic perinatal events.
- Trial name
- MCR-Midwives (NCT07788508)
- Testing
- Mandala Coloring
- Where
- 8 sites in Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Burnout, Professional, Anxiety
Storytelling Through Music to Improve Well-being Among Homeless Service Providers
Homelessness is a complex social issue and requires a dedicated workforce of helping professionals, including nurses and social workers.
- Conditions
- Burnout, Professional, Anxiety, Depression, Secondary Trauma
- Trial name
- NCT06536387
- Testing
- Storytelling Through Music
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Depression, Bipolar Affective Disorder
The Efficacy of a Transdiagnostic Sleep and Circadian Intervention for Patients With Mental Disorders and Sleep Problems
The aim of this study is to examine the effect of a non-pharmacological transdiagnostic sleep intervention as add on to standard treatment for bipolar disorder, depression and attention deficit disorder.
- Conditions
- Depression, Bipolar Affective Disorder, Attention Deficit Disorder
- Trial name
- NCT05406414
- Testing
- Transdiagnostic sleep and circadian treatment, Active waitlist control group
- Where
- Denmark
- Volunteers
- 88 people
- Sponsor
- University of Aarhus
Suicidal Ideation, Suicide, Attempted
The Group Risk Reduction Intervention Therapy (GRRIT) Project
Investigators will evaluate a group format adaptation of Brief Cognitive-Behavioral Therapy for Suicide (i.e., G-BCBT) on suicide ideation (Aim 1), ability to use coping strategies (Aim 2), and overall mental health (exploratory…
- Conditions
- Suicidal Ideation, Suicide, Attempted, Coping Skills, Depression
- Trial name
- ProjectGRRIT (NCT05401838)
- Testing
- Group Brief Cognitive-Behavioral Therapy (G-BCBT), Dialectical Behavior Therapy (DBT) Skills Group
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- University of North Carolina, Charlotte
HIV Infections, Pregnancy Related
Adaptation of an Intervention Addressing Barriers to PrEP Use Among Pregnant Women in Zimbabwe
The purpose of this study is to develop a multi-level PrEP adherence and persistence intervention as an adaptation of the TENDAI ('grateful' in Shona) program, a problem-solving approach to reduce depression and increase HIV…
- Conditions
- HIV Infections, Pregnancy Related, Depression, Anxiety
- Trial name
- TENDAI4PrEP (NCT06226155)
- Testing
- TENDAI4PrEP, Enhanced treatment as usual
- Where
- Zimbabwe
- Volunteers
- 165 people
- Sponsor
- Massachusetts General Hospital
Opioid Induced Respiratory Depression
Critical Respiratory Events in Children Requiring Naloxone: Naloxone Use as Opioid Safety Measure
Opioids are the mainstay of analgesia in hospitalized children but opioid therapy is associated with life-threatening respiratory depression requiring antagonism with naloxone.
- Trial name
- NCT01860885
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Depression, Postpartum
Multimodal Biomarkers and Precision TMS for Postpartum Depression
The purpose of this study is to identify multimodal biological markers associated with postpartum depression (PPD) and to evaluate the effectiveness of precision brain stimulation treatment.
- Trial name
- MOTHER-TMS (NCT07757815)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- 2 sites in Macau
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- University of Macau
COVID-19 Pandemic, Yoga
Effect of Yoga-based Exercises of Healthcare Workers During COVID-19 Pandemic: Prospective Clinical Trial
To investigate the effect of yoga-based exercises therapy on functional capacity, dyspnea, quality of life, depression, anxiety, and sleep quality in healthcare professionals following COVID-19.
- Conditions
- COVID-19 Pandemic, Yoga, Exercise Therapy, Mind-Body Therapies
- Trial name
- NCT05279443
- Testing
- yoga-based exercises therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Ankara City Hospital Bilkent
Alzheimer Disease, Major Depressive Disorder
Aβ Dynamics in LLMD
This study will examine the biological factors that may modulate the relationship between depression and the development of Alzheimer's disease (AD).
- Trial name
- NCT05004987
- Testing
- Escitalopram Oxalate
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Anxiety, Depression
Ginger.io Behavioral Health Study
This Study will evaluate the impact of a smartphone-based platform on a range of outcomes for medically-underserved patients with mood disorders (e.g.
- Conditions
- Anxiety, Depression, Bipolar I Disorder, Bipolar II Disorder
- Trial name
- NCT02491307
- Testing
- Ginger.io Smartphone Application
- Where
- 4 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Community Health Center, Inc.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.