Clinical trials: Depressed
Major Depressive Disorder, Persistent Depressive Disorder
Personalized Indications for CBT and Antidepressants in Treating Depression
Depression currently affects close to 2 million Canadians and is the leading cause of disability worldwide. Pharmacological treatments (antidepressant medication) and psychological treatments such as cognitive-behavioural therapy…
- Trial name
- CANBIND6 (NCT02752542)
- Testing
- Cognitive Behavioral Therapy, Pharmacotherapy
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Nova Scotia Health Authority
Depression
To Demonstrate the Relative Bioavailability of Desipramine Hydrochloride Tablets
To demonstrate the relative bioavailability of Desipramine Hydrochloride tablets.
- Trial name
- NCT00913822
- Testing
- Desipramine Hydrochloride 100 mg Tablets (Cord Laboratories), Norpramin 100 mg Tablets (Merrell Dow Pharmaceuticals, Inc.)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sandoz
Post-Traumatic Stress Disorder, Depression
Long Term Health Outcomes of Women Veterans' Service During the Vietnam Era
Little is known about the long-term health and mental health status of women Vietnam veterans. For many of these women, the effects of this war are still present in their daily lives.
- Conditions
- Post-Traumatic Stress Disorder, Depression, Diabetes, Cardiovascular Disease
- Trial name
- Health ViEWS (NCT00958061)
- Where
- United States
- Volunteers
- 4,219 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Breast Cancer
Psychosocial Adjustment of Patients and Their Partners Following Breast Cancer Diagnosis
The purpose of this study is to describe psychosocial adjustment in patients with breast cancer and their cohabiting partners/spouses throughout the cancer trajectory, to study mutual influences of the partner on the patient and…
- Trial name
- NCT01392066
- Testing
- questionnaire
- Where
- Denmark
- Volunteers
- 1,584 people
- Sponsor
- University of Southern Denmark
Mild Cognitive Impairment, Older People
Effects of Cognitive Stimulation in Older People With Mild Cognitive Impairment
Mild cognitive impairment is becoming one of the most common cynical manifestations that affect older people. That is why there is a need to investigate non-pharmacological interventions that help to improve or maintain this…
- Trial name
- NCT04663256
- Testing
- Cognitive stimulation group
- Where
- Spain
- Volunteers
- 85 people
- Sponsor
- University of Jaén
Maternal Depression, Parenting Behavior
Healthy Moms-Healthy Kids: Reducing Maternal Depression for Better Outcomes in Head Start Children
Maternal depression is a pervasive problem that disproportionately affects low-income mothers. The effects of depression on mothers and their parenting result in many negative outcomes for children, particularly in terms of…
- Conditions
- Maternal Depression, Parenting Behavior, Health, Interpersonal Relationships
- Trial name
- NCT02145273
- Testing
- Interpersonal Psychotherapy for Depression -Group
- Where
- 2 sites in United States
- Volunteers
- 208 people
- Sponsor
- University of Southern California
Cognitive Impairment, Mild, Depressive Symptoms
Brain Stimulation and Enhancing Cognition in Older Adults
The aim of the current research is to evaluate the efficacy of a combination of Mindfulness-Based Stress Reduction (MBSR) and transcranial direct current stimulation (tDCS) to improve cognitive function in individuals with…
- Conditions
- Cognitive Impairment, Mild, Depressive Symptoms, Anxiety
- Trial name
- NCT03653351
- Testing
- Active Transcranial Direct Current Stimulation (tDCS)
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Washington University School of Medicine
Depression, Anxiety
IntelliCare Study: Artificial Intelligence in a Mobile (AIM) Intervention for Depression
This study will evaluate and compare a smartphone intervention for depression and anxiety that uses machine learning to tailor treatment for participants with the same intervention without the machine learning component.
- Trial name
- AIM (NCT02801877)
- Testing
- IntelliCare, Hub App with the Recommender System, Coaching
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- Northwestern University
Depression in Adolescence, Antidepressant Activity in Healthy Volunteers
Fluoxetine and Understanding Social Experiences
Adolescence is a critical developmental period marked by significant social, cognitive, and emotional changes. Unfortunately, it is also a time when the risk of depression and anxiety rises dramatically.
- Conditions
- Depression in Adolescence, Antidepressant Activity in Healthy Volunteers, Healthy Adult Participants
- Trial name
- FUSE (NCT07456501)
- Testing
- Fluoxetine
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Type2 Diabetes, Type 2 Diabetes Mellitus
Depression & Insulin Sensitivity in Adolescents
There has been a rise in type 2 diabetes (T2D) rates in adolescents, disproportionately in girls from disadvantaged racial/ethnic groups.
- Conditions
- Type2 Diabetes, Type 2 Diabetes Mellitus, Insulin Sensitivity, Insulin Resistance
- Trial name
- NCT03263351
- Testing
- Cognitive-behavioral therapy group, Health education group
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- Colorado State University
Inflammatory Bowel Disease, Anxiety
Managing Stress With Inflammatory Bowel Disease
This study will recruit persons with Inflammatory Bowel Disease. The investigators will contact people in an ongoing study (called IMAGINE) to recruit persons with high levels of stress, anxiety, or depression who are interested…
- Conditions
- Inflammatory Bowel Disease, Anxiety, Depression
- Trial name
- NCT03852745
- Testing
- Cognitive Behavioral Therapy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Mental Health Wellness 1
Resilience and Quality of Life Among Cancer Survivors
The main aim of this study is to evaluate the impact of head \& neck cancer and brain tumors on lives of patients in Pakistan. To the best of the investigators knowledge this will be the first in-depth study to evaluate…
- Trial name
- NCT03466762
- Testing
- Non applicable
- Where
- Pakistan
- Volunteers
- 500 people
- Sponsor
- Aga Khan University
Specific Learning Disorder, Intellectual Disability, Mild to Moderate
SWELE Program: An Unstructured Outdoor Play With Mindfulness-based Interventions to Promote Mental Health Among Students With Special Education Needs
This is an observational study with the aim of SWELE Programme is to raise mental health knowledge and awareness by implementing a play-based approach on Supporting Wellness in E-Child Learning Environments (SWELE) programme…
- Conditions
- Specific Learning Disorder, Intellectual Disability, Mild to Moderate, Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- SEN (NCT06112483)
- Testing
- SWELE Programme
- Volunteers
- 1,064 people
- Sponsor
- Chinese University of Hong Kong
Depressive Symptoms, Emotional Depression
Parenting-STAIR Modular for Military Fathers and OCONUS Families
The goal of this clinical trial is to learn if a family-based treatment called Parenting-STAIR-Modular (PSTAIR-M) can help military parents recover from trauma, strengthen emotion regulation skills, and improve parent-child…
- Conditions
- Depressive Symptoms, Emotional Depression, Depression, Parent Child Relationship
- Trial name
- NCT07843654
- Testing
- Parenting-STAIR Modular (PSTAIR-M), Treatment as Usual (TAU)
- Where
- 6 sites in United States, South Korea
- Volunteers
- 243 people
- Sponsor
- New York University
Anxiety, Anxiety Disorders
Transdiagnostic, Cognitive and Behavioral Intervention for in School-aged Children With Emotional and Behavioral Disturbances
Background Impairing emotional and behavioural problems are common in children and adolescents and mark a three-fold increased risk of mental disorder in young adulthood.
- Conditions
- Anxiety, Anxiety Disorders, Depressive Symptoms, Depressive Disorders
- Trial name
- MindMyMind RCT (NCT03535805)
- Testing
- Mind My Mind (MMM), Treatment as Usual (TAU)
- Where
- Denmark
- Volunteers
- 396 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Emotion Regulation, Stress
Optimization of a Mobile Transdiagnostic Emotion Regulation Intervention for University Students
This study will explore the functioning of a mobile transdiagnostic emotion regulation intervention designed for university students to optimize the uptake and the effectiveness of the intervention.
- Conditions
- Emotion Regulation, Stress, Depressive Symptoms, Anxiety
- Trial name
- NCT05576883
- Testing
- Transdiagnostic emotion regulation intervention
- Where
- Netherlands
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Erasmus University Rotterdam
Postpartum Depression, Postpartum Anxiety
Mother-infant Bonding in the Brain: a Mindfulness-based Intervention
The study investigates the effectiveness of the mindfulness-based intervention "Mindful with your Baby" in women with babies between 5-9 months postpartum who experience heightened levels of postpartum depression, anxiety and/or…
- Conditions
- Postpartum Depression, Postpartum Anxiety, Parental Stress
- Trial name
- NCT05830266
- Testing
- "Mindful with your Baby" group-based therapist-guided intervention, "Mindful with your baby" self-guided online intervention
- Where
- Netherlands
- Volunteers
- 64 people
- Sponsor
- Tilburg University
Aging, Elderly
Successful Aging and Age-related Decline
Recent studies have shown promising cognitive and physical interventions aimed at slowing down ageing-related declines in quality of life, but they lack strong ecological validity (brief durations, unrealistic goals, no…
- Conditions
- Aging, Elderly, Cognitive Decline, Physical Decline
- Trial name
- MyAgeWell (NCT06376656)
- Testing
- Cognitive stimulation, Physical activity
- Where
- Malaysia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Sunway University
Depression, Anxiety
Meru Health Program for Cancer Patients With Depression and Anxiety
The primary objective of this study is to evaluate clinical outcomes among people with cancer who participate in a 12-week therapist-supported digital mental health intervention (DMHI) called the Meru Health Program (MHP).
- Trial name
- NCT05588622
- Testing
- Meru Health Program
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Meru Health, Inc.
DGBI, Depression/Anxiety
Feasibility and Acceptability of an Online ACT Intervention for Disorders of Gut-Brain Interaction
The goal of this clinical trial is to assess the acceptability, feasibility, and usability of the iACTforDGBI intervention among patients with Disorders of Gut-Brain Interaction (DGBI).
- Trial name
- iACTforDGBI (NCT06887751)
- Testing
- Acceptance and Commitment Therapy (ACT), Psychoeducation
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Örebro University, Sweden
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