Clinical trials: Depressed
Pulmonary Disease, Chronic Obstructive
Pulmonary Rehabilitation in Functional Outcomes and Its Relationship With Morbidity and Mortality in Patients With COPD
Background: The pulmonary rehabilitation effects on various outcomes of COPD are well known. However, they may be lost over time due to poor adherence to therapy with absence of regular exercise maintenance in long term, disease…
- Trial name
- NCT03692793
- Testing
- Pulmonary rehabilitation
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of the State of Santa Catarina
Schizophrenia Disorders, Major Depression
Non-Coding RNAs Gene Expression in Psychiatric Disorders
This study aims to investigate whether specific non-coding RNAs, molecules involved in the regulation of gene expression, are altered in individuals with psychiatric disorders such as schizophrenia, bipolar disorder, major…
- Conditions
- Schizophrenia Disorders, Major Depression, Bipolar Affective Disorders, Obsessive Compulsive Disorder (OCD)
- Trial name
- PsiRNA26 (NCT07649993)
- Testing
- Reverse Transcription Quantitative Polymerase Chain Reaction
- Where
- 5 sites in Italy
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Carmen Concerto
Bipolar Disorder, Anxiety Disorders
Double-Blind Placebo-Controlled Trial of Riluzole in Pediatric Bipolar Disorder
Pediatric Bipolar Disorder (BD) is uncommon in children. Its symptoms include periods of manic behavior (being overly happy or giddy, feeling grandiose, feeling a decreased need for sleep, having too much energy, moving more than…
- Conditions
- Bipolar Disorder, Anxiety Disorders, Bipolar Affective Disorder, Bipolar Depression
- Trial name
- NCT00805493
- Testing
- Riluzole
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- National Institute of Mental Health (NIMH)
Depression, Dementia
Home-delivered Intervention for Depressed, Cognitively Impaired Elders
Among older adults the combination of depression, cognitive impairment (memory problems), and disability contribute to a worsening of physical and mental health and to poor treatment outcomes.
- Conditions
- Depression, Dementia, Geriatrics
- Trial name
- NCT01350349
- Testing
- Problem Adaptation Therapy (PATH), Supportive Therapy
- Where
- 2 sites in United States
- Volunteers
- 134 people
- Sponsor
- Weill Medical College of Cornell University
Depression, Anxiety
Creatine for Depressed Male and Female Methamphetamine Users
Assess the antidepressant/anxiolytic effect of creatine in male and female methamphetamine users Assess creatine's effect on methamphetamine use Assess the safety of creatine in male methamphetamine users with depression
- Conditions
- Depression, Anxiety, Methamphetamine Dependence
- Trial name
- NCT02568878
- Testing
- Creatine monohydrate
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Montana State University
Anxiety, Depression
Internet-delivered Cognitive Behaviour Therapy (ICBT) for Post-secondary Students
Post-secondary students are at an elevated risk for anxiety and depression, with approximately one in three students experiencing clinical levels of symptoms at some point during their academic career.
- Trial name
- NCT04264585
- Testing
- Internet-delivered cognitive behaviour therapy, Motivational Interviewing, Booster Session
- Where
- Canada
- Volunteers
- 308 people
- Sponsor
- University of Regina
Post Traumatic Stress Disorder, Depression
Randomized Control Trial on Trauma Focused CBT in Zambia
The purpose of this study is to study the effectiveness of Trauma Focused Cognitive Behavioral Therapy in subset of children who are affected by trauma with significant mental health symptomatology in order to 1) examine the…
- Conditions
- Post Traumatic Stress Disorder, Depression, Risk Behaviors
- Trial name
- NCT01624298
- Testing
- Trauma Focused Cognitive Behavioral Therapy
- Where
- Zambia
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Postpartum Depression
Interpersonal Therapy-Based Treatment to Prevent Postpartum Depression in Adolescent Mothers
The Specific Aim of this study is to conduct a randomized controlled trial to evaluate whether Project REACH (an interpersonal psychotherapy-based intervention) compared with a didactic attention-control program reduces the risk…
- Trial name
- REACH 2 (NCT01482832)
- Testing
- Interpersonal therapy-based treatment
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Depression, Anxiety
Group Cognitive Behavioral Therapy (CBT) Intervention for Women With Mild to Moderate Depression
The purpose of this study is to develop a structured CBT group intervention for women with depression of mild or moderate severity and to pilot a randomized controlled trial to compare this intervention with usual care in…
- Trial name
- BackonTrack (NCT00663078)
- Testing
- Brief CBT Group therapy
- Where
- 2 sites in United Kingdom
- Volunteers
- 75 people
- Sponsor
- University of Bristol
Mild Depression
Using a Smartphone App to Reduce Cognitive Vulnerability and Mild Depressive Symptoms
Depression is one of the major challenges worldwide, with significant increasing personal, economic, and societal costs. Although empirically supported treatments have been developed, they are not always available for patients in…
- Trial name
- NCT02783118
- Testing
- Self administered online CBT
- Where
- Romania
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Posttraumatic Stress Disorders, Multiple Sclerosis
The Efficacy of EMDR in Patients With PTSD in Multiple Sclerosis
Multiple Sclerosis (MS) can be associated to many psychological symptoms. One of the most relevant is the experience of distress related to the disease, that can lead to the development of Post Traumatic Stress Disorder (PTSD).
- Trial name
- NCT01743664
- Testing
- EMDR, Relaxation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- San Luigi Gonzaga Hospital
Post Menopausal
Effects of Progressive Resistance Training Vasomotor Symptoms in Post Menopausal Women
The study will be a randomized clinical trial and will be conducted in Civil Hospital and Kalsoom Hospital Samundry. This study will be completed in time duration of 10 months after the approval of synopsis.
- Trial name
- NCT06166264
- Testing
- Progressive resistance training, Control group
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Epilepsy, Anxiety
Phenotypic Exploration During Sensory Stimulation in an Acoustic Chamber
An observational behavioural and neurophysiological study of the effects of controlled sensory stimulation (such as music, for example) on brain function
- Conditions
- Epilepsy, Anxiety, Depression Anxiety Disorder
- Trial name
- EMO-INTRA (NCT07544563)
- Where
- France
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Traumatic Brain Injury
ACTIVE: Activity Therapy to Increase Veteran Engagement
Depression is common after traumatic brain injury (TBI) and may have wide-ranging consequences. Post-TBI depression may impede reintegration into the family and community and lead to lower quality of life and heightened suicide…
- Trial name
- ACTIVE (NCT04976621)
- Testing
- Behavioral Activation, Treatment as Usual
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- VA Office of Research and Development
Depression, Anxiety
AWARE Intervention: Feasibility and Efficacy Trial at Three University Health Services Centers
The goal of this study is to test the efficacy and the feasibility of the Asian Women's Action for Resilience and Empowerment (AWARE) intervention, in the real world setting -- student health service centers at Boston University…
- Conditions
- Depression, Anxiety, PTSD, Suicidal Ideation
- Trial name
- NCT03961633
- Testing
- AWARE intervention
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Boston University Charles River Campus
Post-Traumatic Stress Disorder, Depression
Efficacy of EMDR Versus CBT for Post-Traumatic Stress Disorder in Pakistan
This randomized controlled trial compares Eye Movement Desensitization and Reprocessing (EMDR) therapy with Cognitive Behavioral Therapy (CBT) for the treatment of post-traumatic stress disorder (PTSD) in Pakistan.
- Conditions
- Post-Traumatic Stress Disorder, Depression, Anxiety
- Trial name
- NCT06435052
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR) Therapy, Cognitive Behavioral Therapy (CBT)
- Where
- 3 sites in Pakistan
- Volunteers
- 80 people
- Sponsor
- Khushal Khan Khattak Univeristy, Karak, Pakistan
Depression, History of Suicide Attempt
Behavioral Adaptation to Negative Social Cues in Depressed Patients According to Personal History of Suicide Attempt- COMPASS
Social interactions are part of daily life. To decide to interact with someone or not is a routine for humans. To ensure the quality of interpersonal relationships, emotional cues must be taken into account to adapt optimally the…
- Trial name
- COMPASS (NCT03898648)
- Testing
- Waiting room task
- Where
- France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Montpellier
Depressive Symptoms, Aging
Twelve Weeks of Resistance Training is Equally As Effective At Improving Cardiovascular Risk Factors in Older Women with and Without Depression: a Non-randomized Cross-over Trial
Background: the purporse was to evaluate and compare the effects of 12 weeks of resistance training (RT) on cardiovascular disease (CVD) risk factors in older women with and without depressive disorders Methods: We included 79…
- Conditions
- Depressive Symptoms, Aging, Resistance Training, Cardiovascular Risk Factor
- Trial name
- NCT06591325
- Testing
- exercise, Control
- Where
- Brazil
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Major Depressive Disorder
Neutralizing Interleukin (IL)-6
The proposed study aims to establish the feasibility and safety of subcutaneous tocilizumab, a monoclonal antibody (mAb) against interleukin (IL)-6 receptor, in adults with Major Depressive Disorder (MDD) and evidence of…
- Trial name
- NCT07493317
- Testing
- Tocilizumab
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Premenstrual Syndrome, Depression
Combined Hormone Replacement in Menstrually-Related Mood Disorders
This study investigates the effects on symptoms of combined treatment with estrogen and progesterone in women with severe premenstrual syndrome (PMDD).
- Trial name
- NCT00005011
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- National Institute of Mental Health (NIMH)
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