Clinical trials: Depression, Anxiety, PTSD
Depression, Anxiety
Physical Exercise for Treatment of Depression and Anxiety - RCT
In a 12 week randomly controlled open trial 102 participants with symptoms of depression and/or anxiety will be exposed to either aerobic high intensity training (HIT) or relaxation therapy.
- Trial name
- FYPO (NCT04714528)
- Testing
- Physical Exercise, Relaxation Therapy
- Where
- Sweden
- Volunteers
- 87 people
- Sponsor
- Region Örebro County
Anxiety, Depression
Stanford RAD-AT Study (Research on Anxiety and Depression - Anhedonia Treatment)
This research study is aimed at understanding behaviors and brain circuits that relate to anxiety and depression. Our goal is to learn which circuits of the brain are involved in anxiety and how these circuits might affect daily…
- Trial name
- NCT02220309
- Testing
- Pramipexole Oral Tablet
- Where
- 3 sites in United States
- Volunteers
- 167 people
- Sponsor
- Stanford University
Mental Health Disorder, Depression
Mobile Phone Based Intervention to Protect Mental Health in Healthcare Workers at Frontline Against COVID19
This study aims at evaluating the effectiveness of a mobile phone based intervention to prevent and manage mental health problems in healthcare workers at the frontline against COVID-19 in Spain.
- Conditions
- Mental Health Disorder, Depression, Posttraumatic Stress Disorder, Burnout
- Trial name
- PsyCovid_App (NCT04393818)
- Testing
- Intervention App
- Where
- Spain
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Post Traumatic Stress Disorder, Smoking
Computerized Tailored Intervention for Behavioral Sequelae of PTSD in Veterans
This project assesses the usability and feasibility of a multi-behavioral computerized, tailored intervention (CTI) or expert system delivered via the Internet for veterans with Post-Traumatic Stress symptoms.
- Conditions
- Post Traumatic Stress Disorder, Smoking, Anxiety, Depression
- Trial name
- CTI-PTSD (NCT01510834)
- Testing
- Multibehavioral, Computerized Tailored Intervention STR2IVE
- Where
- 3 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- VA Pacific Islands Health Care System
Mental Health Disorder, Post-Traumatic Stress Disorder in Adolescence
Promoting Asylum-seeking and Refugee Children's Coping With Trauma
A short term trauma-focused cognitive- behavioral program to reduce trauma-related mental health problems among asylum-seeking and refugee children.
- Conditions
- Mental Health Disorder, Post-Traumatic Stress Disorder in Adolescence, Depression, Social Anxiety
- Trial name
- NCT03822598
- Testing
- Teaching Recovery Techniques, TRT
- Where
- 16 sites in Norway
- Volunteers
- 170 people
- Sponsor
- Norwegian Institute of Public Health
Fibromyalgia, Psychological Trauma
Augmentation of EMDR With tDCS in the Treatment of Fibromyalgia
Fibromyalgia (FM) is a generalized, widespread chronic pain disorder and has an estimated prevalence of 2%-4% in the general population.
- Conditions
- Fibromyalgia, Psychological Trauma, Depressive Symptoms, Anxiety
- Trial name
- NCT04084795
- Testing
- Eye Movement Desensitization and Reprocessing therapy, transcranial Direct Current Stimulation
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Parc de Salut Mar
Depression, Anxiety
Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors
Conditions treated in intensive care units (ICUs) such as the acute respiratory distress syndrome (ARDS), congestive heart failure, COVID pneumonia, and sepsis are common.
- Conditions
- Depression, Anxiety, Post-traumatic Stress Disorder, Stress
- Trial name
- Blueprint 2 (NCT06538246)
- Testing
- Blueprint, Education program
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Duke University
Posttraumatic Stress Disorders, Depression
Telemedicine for Improved Delivery of Psychosocial Treatments for Post Traumatic Stress Disorder
The objective of the proposed study is to conduct a systematic comparison of post traumatic stress disorder (PTSD) outcomes for veterans receiving exposure therapy via telemedicine versus in-person care.
- Conditions
- Posttraumatic Stress Disorders, Depression, Anxiety
- Trial name
- NCT01158001
- Testing
- Prolonged exposure therapy
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- Veterans Medical Research Foundation
Critical Illness
Integrated Supportive and Palliative Care for Older Adults in the ICU
The National Academy of Medicine and the National Institutes of Health have called for urgent action to improve the care delivered to the nearly 1,000,000 older Americans who die in intensive care units (ICUs) annually, or…
- Trial name
- ProPACC (NCT04921631)
- Testing
- Early Integration of Specialty Palliative Care with Critical Care
- Where
- United States
- Volunteers
- 1,091 people
- Sponsor
- University of Pittsburgh
Mental Disorder, Substance Use Disorders
Supported Employment in Patient Aligned Care Teams
In response to the Rehabilitation Research and Development (RR\&D) Deployment Health Research, this study addresses the delivery of an evidenced-based vocational rehabilitation, specifically Individual Placement and Support…
- Conditions
- Mental Disorder, Substance Use Disorders, Posttraumatic Stress Disorder, Major Depressive Disorder
- Trial name
- NCT02400736
- Testing
- Individual Placement and Support (IPS), Treatment as Usual Vocational Rehabilitation/Transitional Work (TUA-VR)
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- VA Office of Research and Development
PTSD, Stress, Psychological
The Efficacy of a Physical Activity Counselling Intervention on Mental Health in Firefighters
Objectives: The aim of this project will be to evaluate the efficacy of a lifestyle PA counselling program for physically inactive first responders with at least mild symptoms of either anxiety, depression or stress and their…
- Conditions
- PTSD, Stress, Psychological, Depressive Symptoms, Anxiety Disorders and Symptoms
- Trial name
- NCT05061225
- Testing
- Physical activity counselling
- Volunteers
- 60 people
- Sponsor
- KU Leuven
Myasthenia Gravis
Myasthenia Gravis and Psyche
The purpose of the study is to systematically capture and characterize mental comorbidities for patients with myasthenia gravis.
- Trial name
- NCT03205306
- Where
- Germany
- Volunteers
- 1,399 people
- Sponsor
- Charite University, Berlin, Germany
Post Traumatic Stress Disorder, Rape Sexual Assault
Early Psychological Intervention After Rape
Rape is a common cause of post-traumatic stress disorder (PTSD) among women, as around 30-50% will develop PTSD in the aftermath of rape.
- Conditions
- Post Traumatic Stress Disorder, Rape Sexual Assault, Sexual Dysfunctions, Psychological, Pelvic Floor Myalgia
- Trial name
- EIR (NCT05489133)
- Testing
- Modified prolonged exposure
- Where
- 4 sites in Norway
- Volunteers
- 166 people
- Sponsor
- St. Olavs Hospital
Delirium, Cognitive Impairment
Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy
The purpose of this study is to investigate the effectiveness of a preventative low-dose of Haloperidol to prevent delirium in patients undergoing a esophagectomy, pneumonectomy or thoracotomy.
- Conditions
- Delirium, Cognitive Impairment, Post-traumatic Stress Disorder, Depression
- Trial name
- PE-POD (NCT02213900)
- Testing
- Haloperidol
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Indiana University
Post-operative Delirium
EEG Guidance of Anesthesia (ENGAGES-CANADA)
This study examines the potential link between deep levels of anesthesia and delirium.
- Trial name
- ENGAGES (NCT02692300)
- Testing
- EEG-Guided Group
- Where
- Canada
- Volunteers
- 1,225 people
- Sponsor
- University of Manitoba
Intimate Partner Violence, Depression
Feasibility Study for Abused Chinese Immigrant Women
Intimate partner violence (IPV) is a serious social and public health issue. In the U.S., more than 1 in 3 women experience physical or sexual violence, and/or stalking by an intimate partner during their lifetime.
- Conditions
- Intimate Partner Violence, Depression, Anxiety, PTSD
- Trial name
- NCT05011552
- Testing
- Self-Compassion, Health, and Empowerment (SHE), The Control Condition
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Depression, Anxiety
Microcurrent Neurofeedback as an Adjunct to Standard Care for Substance Use Disorders
The goal of this clinical trial is to learn whether adding Microcurrent Neurofeedback (MCN) to standard residential treatment helps adults with substance use disorder more than standard treatment alone.
- Conditions
- Depression, Anxiety, Substance Use Disorder (SUD), Post Traumatic Stress Disorder
- Trial name
- NCT07737652
- Testing
- Microcurrent Neurofeedback (MCN), Standard Care for Substance Use Disorder
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Alabama, Tuscaloosa
PTSD, Alcohol Use Disorder
Peer Delivered, Emotion Regulation-Focused Mental Health Prevention Training for Fire Fighter Trainees
The goal of this clinical trial is to determine if a peer-delivered emotion regulation training (Brief-Unified Protocol) workshop is effective for preventing posttraumatic stress and other psychological health symptoms in…
- Conditions
- PTSD, Alcohol Use Disorder, Depression, Anxiety
- Trial name
- PEER UP (NCT06290778)
- Testing
- Brief Unified Protocol, Psychoeducation
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Post Traumatic Stress Disorder, Depression
Does an Occupational Therapy Program Enhance Mental Health Outcomes for Veterans Who Scuba Dive
The purpose of the study is to investigate whether an occupational therapy program could enhance mental health outcomes for veterans who SCUBA dive.
- Conditions
- Post Traumatic Stress Disorder, Depression, Anxiety, Stress, Psychological
- Trial name
- NCT03928392
- Testing
- SCUBA with Occupational Therapy (OT), Self-Contained Underwater Breathing Apparatus (SCUBA) without OT
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Loma Linda University
Depression, Anxiety, Post Traumatic Stress Disorder
Effects of a Digital Diary on the Psychological Well-being of Former ICU Patients.
Previous research on the impact of a diary on mental symptoms of PICS, PICS-F, and quality of life in former ICU patients and their relatives has focused specifically on a paper diary.
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Quality of Life
- Trial name
- DIPIC (NCT06237699)
- Testing
- Digital ICU diary
- Where
- 4 sites in Netherlands
- Volunteers
- 400 people
- Sponsor
- Erasmus Medical Center