Clinical trials: Depression, Anxiety, PTSD
Dysthymic Disorder
Desvenlafaxine Monotherapy in Dysthymia
This multi-centred study will be conducted at two centres. The design will be an open label, flexible-dose study. This investigation will evaluate the efficacy of Desvenlafaxine monotherapy for patients who meet diagnostic…
- Trial name
- NCT01948895
- Testing
- Desvenlafaxine
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Centre for Addiction and Mental Health
Post Traumatic Stress Disorder, Depression
Does an Occupational Therapy Program Enhance Mental Health Outcomes for Veterans Who Scuba Dive
The purpose of the study is to investigate whether an occupational therapy program could enhance mental health outcomes for veterans who SCUBA dive.
- Conditions
- Post Traumatic Stress Disorder, Depression, Anxiety, Stress, Psychological
- Trial name
- NCT03928392
- Testing
- SCUBA with Occupational Therapy (OT), Self-Contained Underwater Breathing Apparatus (SCUBA) without OT
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Loma Linda University
Major Depressive Disorder, Dysthymic Disorder
Quetiapine in Co-Morbid Depressive and Anxiety Disorders
This multi-centred study will be conducted at three centres. The design will be a randomized, placebo-controlled, parallel-group one.
- Conditions
- Major Depressive Disorder, Dysthymic Disorder, Anxiety Disorders, Generalized Anxiety Disorder
- Trial name
- NCT00688818
- Testing
- Quetiapine
- Where
- 4 sites in Canada
- Volunteers
- 108 people
- Sponsor
- Centre for Addiction and Mental Health
Posttraumatic Stress Disorders, Depression
Telemedicine for Improved Delivery of Psychosocial Treatments for Post Traumatic Stress Disorder
The objective of the proposed study is to conduct a systematic comparison of post traumatic stress disorder (PTSD) outcomes for veterans receiving exposure therapy via telemedicine versus in-person care.
- Conditions
- Posttraumatic Stress Disorders, Depression, Anxiety
- Trial name
- NCT01158001
- Testing
- Prolonged exposure therapy
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- Veterans Medical Research Foundation
Depression, Anxiety
A Retrospective Effectiveness Trial of Ketamine-Assisted Psychotherapy in Adult Patients Coping With Mental Health
Ketamine-Assisted Psychotherapy (KAP) is a relatively new approach for the treatment of mental health issues, which involves the combination of ketamine, a dissociative anaesthetic with psychedelic properties, and psychotherapy…
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder
- Trial name
- NCT05604794
- Testing
- Ketamine-Assisted Psychotherapy (KAP)
- Where
- 11 sites in United States, Canada
- Volunteers
- 1,806 people
- Sponsor
- Field Trip Health
Post-operative Delirium
EEG Guidance of Anesthesia (ENGAGES-CANADA)
This study examines the potential link between deep levels of anesthesia and delirium.
- Trial name
- ENGAGES (NCT02692300)
- Testing
- EEG-Guided Group
- Where
- Canada
- Volunteers
- 1,225 people
- Sponsor
- University of Manitoba
PTSD, Autism Spectrum Disorder High-Functioning
Psychiatric Orders in Psychoanalytic Treatment of ASD
Autism Spectrum Disorder (ASD) is often accompanied by a variety of other symptoms, such as bipolar disorder, Attention Deficit Hyperactivity Disorder (ADHD), Social Anxiety Disorder (SAD), Avoidant Personality Disorder (AvPD)…
- Conditions
- PTSD, Autism Spectrum Disorder High-Functioning, OCD, Agoraphobia With Panic Attacks
- Trial name
- NCT05930912
- Testing
- Psychoanalysis, sertraline 50mg, Duloxetine 20 MG
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Yang I. Pachankis, PhD
PTSD, Depressive Symptoms
Studying the Effectiveness and Implementation of Sudarshan Kriya Yoga for Canadian Veterans With PTSD
We plan to study the reach, effectiveness, adoption, implementation, and maintenance of the virtually-delivered Sudarshan Kriya Yoga (v-SKY) intervention.
- Conditions
- PTSD, Depressive Symptoms, Anxiety, Pain
- Trial name
- NCT05235828
- Testing
- Sudarshan Kriya Yoga (SKY)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Mount Sinai Hospital, Canada
Posttraumatic Stress Disorder, Somatization
Intervention Through EMDR and CBT With Women Victim of Childhood Sexual Abuse. A Randomized Controlled Trial.
This study evaluates the effectiveness of two types of therapy for the treatment of sexual abuse psychological impact on a sample of Spanish women.
- Conditions
- Posttraumatic Stress Disorder, Somatization, Obsessive-Compulsive Disorder, Depression
- Trial name
- NCT04813224
- Testing
- TRAUMA CENTERED EMDR-BASED TREATMENT and TRAUMA-FOCUSED CBT-BASED TREATMENT
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Internacional de Valencia
Critical Illness Recovery, Behavioral Health Concerns
Behavioral Health Collaborative Care Model in Post-ICU Clinic Family Pilot
This pilot study evaluates the feasibility and acceptability of implementing a Behavioral Health Collaborative Care Model (BH CoCM) for family members of ICU survivors.
- Conditions
- Critical Illness Recovery, Behavioral Health Concerns, Anxiety, Depression - Major Depressive Disorder
- Trial name
- NCT07390786
- Testing
- Behavioral Treatment
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Medical University of South Carolina
Intimate Partner Violence, Depression
Psychosocial Intervention With Community Worker Support for Survivors of Intimate Partner Violence
Female survivors of domestic violence (DV) may exhibit various mental health problems. A variety of psychotherapies are available to improve their mental health, however there is uncertainty on which is the best.
- Conditions
- Intimate Partner Violence, Depression, Anxiety, Post-traumatic Stress Disorder
- Trial name
- IPCCOS (NCT03333798)
- Testing
- Cognitive-Behavioral Intervention, Standard psychosocial care
- Volunteers
- 200 people
- Sponsor
- Universidad del Valle, Colombia
Transplantation, Lung, Depression, Anxiety
Prevention of ICU-Related Anxiety in Lung Transplantation by Virtual Reality Therapy - PIRAT Study
ICU patients frequently face complicated recovery processes, including long-term anxiety disorders. Lung transplantation (LTx) offers people with terminal respiratory conditions both the hope of prolonged survival and a better…
- Conditions
- Transplantation, Lung, Depression, Anxiety, PTSD
- Trial name
- PIRAT (NCT05125406)
- Testing
- Exposure therapy with Virtual Reality.
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Convulsion, Non-Epileptic, Conversion Disorder
Treatments for Psychogenic Nonepileptic Seizures (NES)
The investigators propose that treatment of the comorbid disorders (depression, anxiety, and impulsivity) with sertraline in patients with lone psychogenic nonepileptic seizures (NES), will result in a decreased number of NES.
- Conditions
- Convulsion, Non-Epileptic, Conversion Disorder, Depression, Stress Disorders, Post-Traumatic
- Trial name
- NES (NCT00159965)
- Testing
- sertraline
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Rhode Island Hospital
Posttraumatic Stress Disorder, Stress
An Early Intervention to Increase Maternal Self-efficacy After Preterm Birth
This study aims to investigate the effects of an early intervention (joint observation and video feedback) on maternal parenting self-efficacy following a premature birth.
- Conditions
- Posttraumatic Stress Disorder, Stress, Anxiety, Depression
- Trial name
- JOIN (NCT02736136)
- Testing
- joint observation and video feedback
- Where
- Switzerland
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Depression, Anxiety
Physical Exercise for Treatment of Depression and Anxiety - RCT
In a 12 week randomly controlled open trial 102 participants with symptoms of depression and/or anxiety will be exposed to either aerobic high intensity training (HIT) or relaxation therapy.
- Trial name
- FYPO (NCT04714528)
- Testing
- Physical Exercise, Relaxation Therapy
- Where
- Sweden
- Volunteers
- 87 people
- Sponsor
- Region Örebro County
PTSD Symptoms, Violence Prevention
IPV Prevention Among FDP
Forcibly displaced women and their male partners experience compounding social and structural vulnerabilities to intimate partner violence (IPV) and mental health challenges, yet rigorous studies or examples of evidence-based…
- Conditions
- PTSD Symptoms, Violence Prevention, Depression and Anxiety Symptoms
- Trial name
- NCT07775677
- Testing
- EA$E-US, ongoing standard of care
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- George Mason University
Post-traumatic Stress Disorder (PTSD)
A Trial to Assess the Effects of Prazosin or Propranolol on Blood Pressure in the Presence of Brexpiprazole/Sertraline
A Trial to Assess the Effects of Prazosin or Propranolol on Blood Pressure in the Presence of Brexpiprazole/Sertraline
- Trial name
- NCT05189977
- Testing
- Propranolol, Prazosin
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Sexual Assault and Rape, Suicidal Thoughts
BEAR for Women Who Have Experienced Sexual Assault and Have Suicidal Thoughts
The goal of this clinical study is to learn if the BEAR intervention effects outcome in women who have experienced sexual assault (broadly defined) and who have suicidal thinking.
- Trial name
- BEAR-SI (NCT07902050)
- Testing
- BEAR Therapeutic Group
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Stanford University
Borderline Personality Disorder, Depressive Disorder
Systematic Use of Telepsychiatry for Outpatients
Implementation and evaluation of video consultation in psychiatric outpatient treatment. The study will focus on patients' experiences regarding the use of VC.
- Conditions
- Borderline Personality Disorder, Depressive Disorder, Ptsd, Anxiety Disorders
- Trial name
- NCT05516238
- Testing
- Case management
- Where
- Denmark
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Psychiatric Research Unit, Region Zealand, Denmark
Anxiety Disorders, Depression
Hot Water Immersion Therapy for Mental Health
In 2016, it was estimated that nearly 1 billion people worldwide were affected by a mental or addictive disorder, and were associated with considerable excess mortality. Acute heat therapy sessions (e.g.
- Conditions
- Anxiety Disorders, Depression, Post-traumatic Stress Disorder, Heat
- Trial name
- WITHME (NCT04793542)
- Testing
- lower-limb hot water immersion
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Lakehead University