Clinical trials: Depression, Anxiety, PTSD
Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder
HBOT Effects on First Responders' Cognition and Well-Being
The goal of this study is to examine changes in cognitive functioning and post-concussive symptoms following hyperbaric oxygen therapy (HBOT) in current and former first responders with a history of traumatic brain injury.
- Conditions
- Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder, Anxiety, Depression
- Trial name
- NCT07852728
- Testing
- Hyperbaric Oxygen Therapy (HBOT)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Summit Hyperbarics and Wellness
Lung Diseases, Medication Compliance
Uncontrolled Lower Respiratory Symptoms in the WTC Survivor Program
The purpose of this study is to understand why patients in the World Trade Center program have continuing breathing problems. This study will improve investigators understanding of breathing problems among individuals with World…
- Trial name
- NCT02024204
- Testing
- Fluticasone propionate 230mcg for 3 Months, Current Treatment or no treatment, Salmeterol 21mcg for 3 Months
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Psychiatric Disorders, Depression - Major Depressive Disorder
Implementing Action-Based Cognitive Remediation for Transdiagnostic Cognitive Difficulties in a Tertiary Mental Health Hospital
Psychiatric conditions are each defined by different set of symptoms, however, they often share common characteristics such as impairments in cognitive and social functioning.
- Conditions
- Psychiatric Disorders, Depression - Major Depressive Disorder, Schizophrenia and Other Psychotic Disorders, Anxiety and Mood Disorders
- Trial name
- NCT07506070
- Testing
- Action-Based Cognitive Remediation
- Volunteers
- 160 people
- Sponsor
- The Royal Ottawa Mental Health Centre
Stress, Psychological, Sleep Disturbance
The Effect of a Combined Nature-based and Virtual Mindfulness Intervention on Perceived Stress in Healthcare Workers
Rationale: Healthcare workers that care for patients with COVID-19 are at increased risk for stress-related symptoms. When these symptoms are chronic, they can result in burnout and other mental health conditions that can…
- Conditions
- Stress, Psychological, Sleep Disturbance, Burnout, Caregiver, Posttraumatic Stress Disorder
- Trial name
- NCT04846790
- Testing
- Nature Only, Nature+Mindfulness
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Depression, Physical Inactivity
Physical Exercise as Adjunctive Therapy for Affective Disorder and Anxiety
"Braining" is a clinical method for physical exercise as adjunctive therapy in psychiatric care. The core components are personnel-led group training sessions and motivating contact with psychiatric staff, as well as measurement…
- Conditions
- Depression, Physical Inactivity, Bipolar Disorder, Anxiety Disorders
- Trial name
- NCT05157386
- Testing
- Braining
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Stockholm
Mental Illness
Validation of French PHQ-4 and PC-PTSD-5 Screening Scales
Mental illness is a major public health issue. It affects one in five people, represents the largest expense for health insurance (14%), is the leading cause of years lived with disability, and suicide is the main cause of death…
- Trial name
- DEPSYSTAGE (NCT07396623)
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post Traumatic Stress Disorder (PTSD), Depression
Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans
The VA wants to understand what type of integrative and whole health approaches are helpful for Veterans. The study is comparing two primary care based mental health treatments, a mindfulness class that teaches mindfulness…
- Conditions
- Post Traumatic Stress Disorder (PTSD), Depression, Anxiety
- Trial name
- NCT06162741
- Testing
- Primary Care Brief Mindfulness Training (PCBMT), Moving Forward (MF)
- Where
- 4 sites in United States
- Volunteers
- 300 people
- Sponsor
- VA Office of Research and Development
Depression, Posttraumatic Stress Disorder
Evaluation of Outcomes Following Surf Therapy
The current study evaluates psychological and physical health outcomes for active-duty service members following participation in an established surf therapy program.
- Trial name
- NCT02857751
- Testing
- Surf therapy
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Depression, Anxiety, PTSD
A Scalable Model for Promoting Functioning and Well-Being Among Veterans With a History of Mental Health Challenges Via Meaningful Social Interactions: Project V-SPEAK!
The goal of this study is to refine and test a strategy for engaging veterans with symptoms of depression and/or anxiety as volunteers to help English language learners (ELLs) improve their speaking skills via structured…
- Trial name
- V-SPEAK! (NCT05506839)
- Testing
- Intervention (videoconferencing)
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Major Depressive Disorder, Depression
Testing a Transdiagnostic TMS Treatment Target
The goal of this clinical trial is to test a new brain stimulation treatment target for individuals with depression plus at least one additional psychiatric disorder.
- Conditions
- Major Depressive Disorder, Depression, Psychiatric Disorder, Mood Disorders
- Trial name
- T5 (NCT06282146)
- Testing
- transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Brigham and Women's Hospital
PTSD, Anxiety
Exploring Medically Perceived Benefits, Use and Interest in Psychedelics and Cannabinoids
The primary objective of this study is to collect insights from first responders and military personnel on their need for, use of, and interest in physical and/or mental health medical marijuana or psychedelic-assisted therapy…
- Conditions
- PTSD, Anxiety, Anxiety Disorders, Depression
- Trial name
- EMPOWER (NCT04965740)
- Testing
- Cannabis
- Where
- Canada
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Empower Research Inc
Anxiety, Anxiety Disorders
The Impact of a School-Based, Trauma-Informed CBT Intervention for Young Women
The purpose of this study is: 1. To conduct a randomized controlled trial to evaluate the impact of Working on Womanhood (WOW), a school-based, trauma-informed counseling and clinical mentoring program for young women in Chicago…
- Conditions
- Anxiety, Anxiety Disorders, Behavioral Symptoms, Depression
- Trial name
- NCT03376633
- Testing
- Working on Womanhood (WOW)
- Where
- United States
- Volunteers
- 5,106 people
- Sponsor
- University of Chicago
Chronic Pain, Chronic Pain Syndrome
Outcomes Mandate National Integration With Cannabis as Medicine
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- OMNI-Can (NCT03944447)
- Testing
- Cannabis, Medical, RYAH-Medtech Inhaler
- Where
- 17 sites in United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- OMNI Medical Services, LLC
Anxiety, PTSD
Evaluation of the H.O.O.V.E.S. Healing Intensives Program
The aim of this study is to measure the impact of these H.O.O.V.E.S. healing intensives on Veteran participants using several psychological instruments.
- Conditions
- Anxiety, PTSD, Depression
- Trial name
- NCT06300255
- Testing
- H.O.O.V.E.S. Healing Intensives
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- VA Salt Lake City Health Care System
PTSD, Depression, Anxiety
Physical Activity Intervention for Trauma Afflicted Refugees
This study evaluates the effects of a 10-session physical activity intervention for trauma afflicted refugees. Half of participants will receive this 10-session physical activity intervention and half of the participants will be…
- Conditions
- PTSD, Depression, Anxiety, Physical Activity
- Trial name
- NCT04065126
- Testing
- Physical activity intervention, Brief psycho-education
- Where
- Sweden
- Volunteers
- 183 people
- Sponsor
- Swedish Red Cross University College
Depression, Postpartum, Anxiety
Preventing Postpartum Depression With Intranasal Oxytocin
The purpose of this study is to test a new treatment for preventing childbirth-related mental illness in postpartum mothers. The treatment is aimed at enhancing maternal bonding, reducing postpartum depression (PPD) and anxiety…
- Trial name
- IN-OXT (NCT02505984)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Massachusetts General Hospital
Bone Marrow Transplant Complications
Virtual Reality Intervention for Patients Undergoing BMT
The goal of this research study is to test the feasibility and preliminary efficacy of using a virtual reality (VR) psychosocial intervention for improving quality of life and psychological distress in patients hospitalized for…
- Trial name
- NCT05629676
- Testing
- BMT-VR
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
Anxiety, Depression
Depression and Anxiety Reduction Treatment for Suicide
The purpose of this study is to test the effectiveness and usability of multiple computer-based treatments for mood and anxiety relevant risk factors.
- Conditions
- Anxiety, Depression, Suicide
- Trial name
- DARTS (NCT01941862)
- Testing
- Psychoeducation and Cognitive Bias Modification
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Florida State University
COVID-19, Pregnancy Complications
Health and Wellbeing of Pregnant and Post-Partum Women During the COVID-19 Pandemic
The purpose of this study is to assess the health and wellbeing of pregnant and recently pregnant women during the COVID-19 pandemic using an online survey.
- Conditions
- COVID-19, Pregnancy Complications, Mental Health Wellness 1, Anxiety
- Trial name
- NCT04385238
- Testing
- This is an online survey with no intervention.
- Where
- United States
- Volunteers
- 6,894 people
- Sponsor
- Pregistry
Anxiety, Acute Stress Disorder
Intervention to Decrease Anxiety in Parents of Infants in the Neonatal Intensive Care Unit (NICU)
Infants born premature face numerous medical problems, causing significant anxiety for their parents. Parents experience a range of negative emotions including concern for the health and well being of their fragile infant, guilt…
- Conditions
- Anxiety, Acute Stress Disorder, Posttraumatic Stress Disorder, Depression
- Trial name
- NCT00186472
- Testing
- Brief Cognitive Behavioral Treatment
- Where
- United States
- Sponsor
- Stanford University