Clinical trials: Depression, Anxiety, PTSD
PTSD (Childbirth-Related), Severe Maternal Morbidity
Debriefing Consult for Psychiatric Symptoms After Severe Maternal Morbidity
The primary objective of this study is to determine if a maternal fetal medicine (MFM) debriefing consult six to eight weeks postpartum reduces self-reported post-traumatic stress, depression, and anxiety symptoms following a…
- Conditions
- PTSD (Childbirth-Related), Severe Maternal Morbidity, Depression - Major Depressive Disorder, Anxiety
- Trial name
- NCT07684521
- Testing
- Virtual maternal fetal medicine debriefing consult
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Cedars-Sinai Medical Center
Post-Traumatic Stress Disorder, Depression
Efficacy of EMDR Versus CBT for Post-Traumatic Stress Disorder in Pakistan
This randomized controlled trial compares Eye Movement Desensitization and Reprocessing (EMDR) therapy with Cognitive Behavioral Therapy (CBT) for the treatment of post-traumatic stress disorder (PTSD) in Pakistan.
- Conditions
- Post-Traumatic Stress Disorder, Depression, Anxiety
- Trial name
- NCT06435052
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR) Therapy, Cognitive Behavioral Therapy (CBT)
- Where
- 3 sites in Pakistan
- Volunteers
- 80 people
- Sponsor
- Khushal Khan Khattak Univeristy, Karak, Pakistan
Posttraumatic Stress, Depression
Internet-Delivered Cognitive Behaviour Therapy for PTSD Among Public Safety Personnel
This study evaluates two Internet-delivered cognitive behavioural therapy (ICBT) interventions: one for symptoms of posttraumatic stress disorder (PTSD) and one for symptoms of anxiety, depression, and PTSD.
- Conditions
- Posttraumatic Stress, Depression, Anxiety
- Trial name
- NCT04335487
- Testing
- PSP PTSD Course, PSP Wellbeing Course
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- University of Regina
Mental Health Disorder, PTSD
Psychosocial and Economic Impacts of Narrative Exposure Therapy for Violence Survivors in Eastern DRC
The objective of the study is to evaluate the impact of Narrative Exposure Therapy (NET) delivered by local counselors, on the mental health and socio-economic empowerment of survivors of Sexual and Gender Based Violence (SGBV)…
- Conditions
- Mental Health Disorder, PTSD, Depression Anxiety Disorder, Gender-based Violence
- Trial name
- NCT04841031
- Testing
- NET Treatment, Alternative Intervention
- Where
- 2 sites in Democratic Republic of the Congo
- Volunteers
- 1,053 people
- Sponsor
- World Bank
Post Traumatic Stress Disorder, Depression
Acceptance and Commitment Group Therapy for Unaccompanied Minors
Unaccompanied minors (UM) are considered to be a highly vulnerable refugee subgroup. Research has indicated that UM experience traumatic events and consequently develop high levels of psychopathology.
- Conditions
- Post Traumatic Stress Disorder, Depression, Anxiety Disorders
- Trial name
- NCT05218031
- Testing
- Acceptance and Commitment Therapy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Cyprus
Domestic Violence, Depression
Cortisol Evaluation in Abuse Survivors
This study looks at the biological effect of domestic violence and abuse (DVA) on women's mental health. The mechanisms through which DVA causes mental disorders are very poorly understood.
- Conditions
- Domestic Violence, Depression, Anxiety, Panic Disorder
- Trial name
- CEASE (NCT01632553)
- Where
- 2 sites in United Kingdom
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Bristol
Postintensive Care Syndrome, Anxiety Disorder
Is Invasive ICU-treatment Associated With Mental Illness?
Understanding long-term complications after intensive care is important to be able to offer prophylactic and therapeutic measures to post-intensive care unit (ICU) patients.
- Conditions
- Postintensive Care Syndrome, Anxiety Disorder, Depression, PTSD
- Trial name
- NCT05137977
- Testing
- Intensive Care
- Volunteers
- 1,048,576 people
- Sponsor
- Uppsala University
Anxiety, PTSD
Chaplain Family Project Trial
Our research team has designed a chaplain delivered intervention focused on surrogate decision makers for hospitalized adults in the ICU.
- Conditions
- Anxiety, PTSD, Depression, Communication
- Trial name
- CFP-RCT (NCT03702634)
- Testing
- Spiritual Care Assessment and Intervention (SCAI) framework
- Where
- 2 sites in United States
- Volunteers
- 192 people
- Sponsor
- Indiana University
Post Intensive Care Syndrome, Narrative Medicine
Effect of Pediatric Intensive Care Unit Diaries on PICS-p
When children become very sick and need to stay in a Pediatric Intensive Care Unit (PICU), it can have a big impact on their recovery and their family's well-being.
- Conditions
- Post Intensive Care Syndrome, Narrative Medicine, Post Traumatic Stress Disorder, Anxiety
- Trial name
- PICS-p (NCT06310109)
- Testing
- PICU diary
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- Bambino Gesù Children's Hospital IRCCS
Sexual Assault and Rape, Suicidal Thoughts
BEAR for Women Who Have Experienced Sexual Assault and Have Suicidal Thoughts
The goal of this clinical study is to learn if the BEAR intervention effects outcome in women who have experienced sexual assault (broadly defined) and who have suicidal thinking.
- Trial name
- BEAR-SI (NCT07902050)
- Testing
- BEAR Therapeutic Group
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Stanford University
Psychological Distress, Depression
Mobile Mindfulness to Improve Psychological Distress After Critical Illness
Many survivors of the intensive care unit (ICU) suffer from persistent symptoms of depression, anxiety, and post-traumatic stress disorder (PTSD).
- Conditions
- Psychological Distress, Depression, Anxiety, Post-traumatic Stress Disorder
- Trial name
- NCT02701361
- Testing
- mobile mindfulness, standard mindfulness, education
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Duke University
Stress, Emotional, Stress-related Mental Disorders
School-Based Intervention to Enhance Resilience and Stress Coping in Rural Chinese Adolescents
This study aims to evaluate the effectiveness of school-based psychological interventions in improving stress resilience and coping skills among adolescents in rural China.
- Trial name
- EASY (NCT07115186)
- Testing
- Psychoeducation, guided written therapy, wait-list condition
- Where
- China
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Peking University
Psychological Distress, Psychological Trauma
Implementing Psychosocial Interventions to Syrian Refugee Women Who Are Exposed to Psychological Trauma
This study assesses severity of trauma, depression and anxiety symptoms of Syrian women under temporary protection who reside in Istanbul and types of exposed trauma that they have experienced.
- Trial name
- NCT03912077
- Testing
- Culturally Adapted Cognitive Behavioural Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Istanbul Sehir University
Stress Disorders, Post-Traumatic
Pharmacologic Treatment of PTSD in Sexually Abused Children
This study will evaluate the benefit of adding sertraline (Zoloft®) to Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) for sexually abused children who have Posttraumatic Stress Disorder (PTSD).
- Trial name
- NCT00078767
- Testing
- Trauma-Focused Cognitive Behavioral Therapy, Sertraline Pill
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
PTSD, Depressive Symptoms
Studying the Effectiveness and Implementation of Sudarshan Kriya Yoga for Canadian Veterans With PTSD
We plan to study the reach, effectiveness, adoption, implementation, and maintenance of the virtually-delivered Sudarshan Kriya Yoga (v-SKY) intervention.
- Conditions
- PTSD, Depressive Symptoms, Anxiety, Pain
- Trial name
- NCT05235828
- Testing
- Sudarshan Kriya Yoga (SKY)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Mount Sinai Hospital, Canada
Post Traumatic Stress Disorder (PTSD), Anxiety
COVID-Impact "Psychological IMPACT of Covid-19 on AP-HP Staff"
The epidemic of coronavirus induces a major influx of patients implying a rapid modification of the organizations, a work overload and a significant stress for the care teams and supports of the hospitals of the Assistance…
- Conditions
- Post Traumatic Stress Disorder (PTSD), Anxiety, Depression, Epidemic Disease
- Trial name
- Covid-Impact (NCT04558437)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 20,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Major Depressive Disorder, Dysthymic Disorder
Quetiapine in Co-Morbid Depressive and Anxiety Disorders
This multi-centred study will be conducted at three centres. The design will be a randomized, placebo-controlled, parallel-group one.
- Conditions
- Major Depressive Disorder, Dysthymic Disorder, Anxiety Disorders, Generalized Anxiety Disorder
- Trial name
- NCT00688818
- Testing
- Quetiapine
- Where
- 4 sites in Canada
- Volunteers
- 108 people
- Sponsor
- Centre for Addiction and Mental Health
Post-Traumatic Stress Disorder
Bringing What Works to Youth in Corrections: A Trauma Intervention
Youth with mental illnesses are disproportionately represented in juvenile correctional facilities and limited evidence exists about effective treatments in this setting.
- Trial name
- NCT01560728
- Testing
- Trauma-Focused Cognitive Behavioral Therapy
- Where
- 3 sites in United States
- Volunteers
- 57 people
- Sponsor
- University of Texas at Austin
Miscarriage
Interest of a Short Early Psychological Care in Women With Miscarriage
Miscarriage is a very common complication of pregnancy, accounting for 15.3% (95% CI 12.5-18.7%) of diagnosed pregnancies. Miscarriage would affect one in ten women during her lifetime.
- Trial name
- MisTher (NCT05653414)
- Testing
- short early psychological care associated with encouragement of early support consultation with generalist practitioner or midwife, encouragement of early support consultation with generalist practitioner or midwife
- Volunteers
- 932 people, healthy volunteers welcome
- Sponsor
- Université de Reims Champagne-Ardenne
PTSD, Depression
Arts and Movement Therapies for Trauma
The current goal of this project is to subjectively and objectively assess the efficacy of arts and movement interventions--including dance/movement therapy, art therapy and mindful yoga for youth and adults exposed to trauma…
- Conditions
- PTSD, Depression, Anxiety, Stress
- Trial name
- NCT03515564
- Testing
- Dance/Movement Therapy, Art Therapy, Mindful Yoga
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- Wayne State University